Prevention of transplant renal artery stenosis.

Abstract:

:Transplant renal artery stenosis occurred in 17 of 142 consecutive transplants (12 percent). All stenoses were in the renal artery distal to the anastomosis and two separate forms are recognized: angulation and segmental stenosis. Successful surgical correction in 12 of 17 patients relieved the hypertension and resulted in improved renal function. No patients receiving dipyridamole, a drug which inhibits platelet aggregation and intravascular fibrin deposition, developed segmental renal artery stenosis. No other factors could be identified which were important in either causing or preventing renal artery stenosis. Since intrarenal vascular changes are an integral aspect of rejection, the protection afforded by dipyridamole against segmental renal artery stenosis indicates that segmental stenosis is probably a manifestation of rejection.

journal_name

Surgery

journal_title

Surgery

authors

Kauffman HM,Sampson D,Fox PS,Doyle TJ,Maddison FE

subject

Has Abstract

pub_date

1977-02-01 00:00:00

pages

161-7

issue

2

eissn

0039-6060

issn

1532-7361

pii

0039-6060(77)90188-X

journal_volume

81

pub_type

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