Abstract:
:Advances in radiation techniques and increased dosage have improved the cure rate of patients with cancer of the cervix to 65 percent. Associated with this increased dosage (betatron, 5,250 r and intracavitary 137-cesium, 4,000 r at point A) has been a serious complication incidence of 10 percent. Major intestinal complications usually become manifest within an 8 to 24 month period following radiation. Few are associated with tumor and the majority are amenable to surgical correction. Rectosigmoid stenosis is a common and frequently unrecognized complication. The 8 to 12 cm. segment of rectosigmoid, with its rigid wall and narrowed lumen, can be recognized on barium examination. The symptoms are those on incomplete obstruction and deterioration, frequently confused with tumor progression. Thirty-one patients have been treated by resection and low anterior anastomosis with relief of symptoms. Rectosigmoid stenosis progressing to necrosis, perforation, or fistula (an additional 29 patients) is treated best by the Hartmann operation as a first stage. This procedure has been less complicated than either colostomy alone or resection and anastomosis. Fifteen patients with low level rectovaginal fistula or stenosis were treated by defunctioning sigmoid colostomy. A loop transverse colostomy was unsatisfactory. Ileorectovaginal fistulas occurred in an additional six patients. Preoperative investigation should establish the presence or absence of an ileal component in all fistulas. Radiation ileitis is rare as an isolated finding but frequently is associated with severe rectosigmoid damage. Surgical treatment is seldom necessary but, if indicated (ten patients), resection appears to be preferable to bypass.
journal_name
Surgeryjournal_title
Surgeryauthors
Palmer JA,Bush RSsubject
Has Abstractpub_date
1976-10-01 00:00:00pages
458-64issue
4eissn
0039-6060issn
1532-7361journal_volume
80pub_type
杂志文章相关文献
SURGERY文献大全abstract::The findings of decreased adenosine triphosphate (ATP) levels in liver, kidney, and other tissues of animals in hemorrhagic shock were the rationale for previous experimental attempts to improve cell function by administration of fluids that contained high concentrations of ATP. The beneficial effects of this resuscit...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1987-09-01 00:00:00
abstract:BACKGROUND:We hypothesized that intraoperative parathyroid hormone monitoring (IOPTH) reliably would detect double parathyroid adenomas. METHODS:This was a retrospective study of 20 patients undergoing conventional parathyroidectomy with resection of exactly 2 abnormal glands. Full exploration was performed regardless...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2001.118385
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Our ability to predict respiratory compromise during general anesthesia in a child with an anterior mediastinal mass is limited. Two prior reports have found a correlation between adequacy of ventilation during general anesthesia and the tracheal cross-sectional area obtained from computed tomograms (compute...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/s0039-6060(05)80360-5
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND:The surgical workforce particularly in rural regions needs novel approaches to reinforce the skills and confidence of health practitioners. Although conventional telementoring systems have proven beneficial to address this gap, the benefits of platforms of augmented reality-based telementoring in the coachin...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2019.11.008
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Although the price hospitals charge for operations has broad financial implications, hospital pricing is not subject to regulation. We sought to characterize national variation in hospital price markup for major cardiothoracic and gastrointestinal operations and to evaluate perioperative outcomes of hospital...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2016.03.014
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:To assess trainee satisfaction in their surgery residency with a validated instrument and identify the contributing factors. BACKGROUND:Currently, surgery is deemed unattractive by medical students and ignored by many candidates planning to enter an academic career. New insights on the rational for such lack...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.07.037
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:There is currently little information regarding the impact of procedure volume on outcomes after open inguinal hernia repair in the United States. Our hypothesis was that increasing procedure volume is associated with lesser rates of reoperation and resource use. METHODS:The database of the Statewide Planni...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2015.03.058
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Interleukin 12 (IL-12) p70 is a heterodimeric protein (p35, p40 subunits) that promotes T-helper TH1-type cytokine response. In critically ill patients, after severe trauma or sepsis, IL-12 production is markedly impaired. We tested the hypothesis that deficiency of the transcription factor c-fos will increa...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:The current study was designed to determine the effects of antibody blockade of mucosal addressin cell adhesion molecule-1 (MAdCAM-1) on the proinflammatory activity of mesenteric lymph after hemorrhagic shock and resuscitation (HS/R). METHODS:Rats were subjected to HS/R with or without treatment with MAdCA...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2015.12.013
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Nosocomial pneumonia (NP) in injured patients is a significant clinical problem. We hypothesize that the pathogenesis of NP in injured patients involves an imbalanced cytokine response within the alveolar airspace that may inhibit effector cell function. METHODS:Proinflammatory (IL-8) and anti-inflammatory ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2001.117105
更新日期:2001-10-01 00:00:00
abstract::The systolic blood pressure measured in the fingers and wrists by the spectroscopic method and in the arm by auscultation were correlated with angiographic evidence of organic arterial obstruction in 29 patients. The pressures also were measured in 14 normal people. Results in the normal people suggest that a differen...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1975-04-01 00:00:00
abstract:BACKGROUND:Tumor-associated lymphatic networks are the primary routes for tumor cell dissemination and metastasis. Behind the background of possible lymphangiogenesis-associated therapies, the clinical impact of lymphangiogenesis (measured by lymphatic microvessel density [LMVD]) and specific lymphovascular invasion (L...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2012.10.007
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:This study examines factors associated with the performance of orthotopic liver transplantation (OLT) without red blood cell (RBC) transfusion. METHODS:Between January 1992 and December 1994, 306 primary OLTs were performed with recipients divided into two groups: group 1 patients (61 recipients, 20% of tot...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/s0039-6060(96)80019-5
更新日期:1996-10-01 00:00:00
abstract::We have investigated the effect of bile on fat-stimulated release and basal plasma levels of cholecystokinin-33/39 (CCK) and neurotensin in six awake dogs prepared with chronic gastric and duodenal cannulas. Experimental bile diversion was achieved by catheterization of the common bile duct through the duodenal cannul...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1986-08-01 00:00:00
abstract:BACKGROUND:Estrogen receptor (ER)-positive breast carcinomas possess a less aggressive phenotype than ER-negative breast carcinomas. We hypothesize that a set of genes exists that is expressed only in ER-negative breast carcinomas, which account for the more malignant phenotypic characteristics of these tumors. METHOD...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1998-08-01 00:00:00
abstract::The experience with 14 patients with infected aortic bifurcation grafts has been reviewed. Factors which appeared to predispose to infection in 11 patients included "re-do" operations, concomitant cholecystectomy or gastrostomy, and ruptured abdominal aneurysm. A mixture of gastrointestinal organisms was responsible f...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1976-11-01 00:00:00
abstract:BACKGROUND:Plasma from laparotomized mice has been shown to stimulate in vitro tumor growth when compared to results with preoperative plasma. This study assessed the effect of plasma from patients who underwent major open (OS) or laparoscopic surgery (LS) on in vitro tumor cell growth. METHODS:Eighty-four patients un...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2002.125308
更新日期:2002-08-01 00:00:00
abstract::The exact role that the American Board of Surgery In-Training Examination plays in resident evaluation remains poorly defined. We have required that all residents take the In-Training Examination annually. An analysis was performed of the results of the In-Training Examination and the Qualifying Examination of the Ame...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1984-07-01 00:00:00
abstract::Severe abdominal pain was the major indication for operation in 85 patients with chronic pancreatitis. Preoperative endoscopic retrograde cholangiopancreatography (50 patients) or intraoperative pancreatic ductograms (44 patients) demonstrated dilated or obstructed major pancreatic ducts in 50 patients (59%), nonvisua...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1984-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Laparoscopic surgery for colorectal cancer is currently being evaluated in humans. The aim of this study was to examine the effect of laparoscopy on intraperitoneal tumor growth and distant metastases in an animal model. We also examined the effect of combining laparotomy with laparoscopy and on inf...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.1999.99056
更新日期:1999-07-01 00:00:00
abstract::Pancreatic polypeptide (PP) deficiency has been associated with impaired hepatic sensitivity to insulin and pancreatogenic diabetes in chronic pancreatitis. Since pancreatic resection might also result in PP deficiency, hepatic responses to insulin infusion (0.25 mU/kg/min) were determined by the euglycemic glucose cl...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
abstract:BACKGROUND:In the developmental stage, pancreas derives from the endodermal cells where the transcription factor, pancreatic duodenal homeobox gene-1 (pdx-1) is expressed. In adulthood, pdx-1 expression is localized to pancreatic beta cells, which is necessary for maintenance of beta cell function. Recently, ectopic ex...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2006.06.014
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:Failure to achieve primary fascial closure (PFC) after damage control laparotomy is costly and carries great morbidity. We hypothesized that time from the initial laparotomy to the first take-back operation would be predictive of successful PFC. METHODS:Trauma patients managed with open abdominal techniques...
journal_title:Surgery
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.surg.2014.04.019
更新日期:2014-08-01 00:00:00
abstract::Perirectal and perineal infections represent a life-threatening complication of hematologic diseases associated with granulocytopenia. Early and aggressive surgical management is essential. This should include hemodynamic support and monitoring, broad-spectrum antibiotics, wide surgical debridement, and a totally dive...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1986-11-01 00:00:00
abstract::A case of paraprosthetic-enteric fistula is presented and the total reported literature of 21 cases is reviewed. Paraprosthetic-enteric fistula is a complication of aortic revascularization with synthetic prostheses. The entity is characterized by erosion of the gastrointestinal tract by an underlying prosthesis but a...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1977-05-01 00:00:00
abstract::Twenty-six cases of carcinoid-related mesenteric angiopathy and intestinal infarction (three from our institution and 23 previously reported cases) were reviewed. Twenty patients presented with acute abdominal findings, including peritonitis (13 cases), intestinal obstruction (five cases), and bleeding per rectum (two...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1981-10-01 00:00:00
abstract:BACKGROUND:Postoperative cervical hemorrhage is a rare but life-threatening complication that can cause severe morbidity. Different mechanisms leading to asphyxia have been described based only on clinical observation. METHODS:We performed a series of in vivo animal studies simulating post-thyroidectomy hemorrhage and...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2018.05.022
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Interleukin (IL)-18 is a proinflammatory cytokine involved in the regulation of cell-mediated and innate immune responses to infection, trauma, and inflammation. Elevated levels of IL-18 have been noted to correlate with organ dysfunction after injury. This study evaluates the relationship between IL-18 prom...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2003.248
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the genotype-phenotype relationship of pancreatic neuroendocrine tumors in patients with multiple endocrine neoplasia type 1 treated at our institution. METHODS:We conducted a retrospective chart review of all patients with multiple endocrine neoplasia type 1 treated...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2017.04.044
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:We have developed a novel molecular method of diagnosis using the technique of transcriptase-reverse transcriptase concerted reaction (TRC) for the detection of cancer micrometastasis. This study prospectively examined the clinical importance of the TRC diagnosis with peritoneal lavage fluids collected from gas...
journal_title:Surgery
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.surg.2013.10.004
更新日期:2014-03-01 00:00:00