Electroacupuncture Pretreatment Alleviates Cerebral Ischemia-Reperfusion Injury by Increasing GSK-3β Phosphorylation Level via Adenosine A1 Receptor.

abstract：:Neonatal hyperbilirubinemia is a common problem with potentiality to cause irreversible brain damage. Reduction of serum bilirubin level is essential to minimize such damage. Compact fluorescent tubes, halogen bulbs, fiber optic blankets, and LEDs are commonly used light sources for phototherapy with varying efficacie...

journal_title：BioMed research international

authors： Gutta S,Shenoy J,Kamath SP,Mithra P,Baliga BS,Sarpangala M,Srinivasan M

更新日期：2019-04-11 00:00:00

abstract：UNLABELLED:The aims of this study were first to clearly define two different entities: locoregional recurrences and limited metastatic disease and secondly to evaluate the place of extensive surgery in these two types of recurrence. MATERIAL AND METHODS:Twenty-four patients were followed from June 2004 until May 2014....

journal_title：BioMed research international

authors： Berlière M,Duhoux FP,Taburiaux L,Lacroix V,Galant C,Leconte I,Fellah L,Lecouvet F,Bouziane D,Piette P,Lengele B

更新日期：2015-01-01 00:00:00

abstract：Background:BMPER has been reported to be associated with the biological behavior of a few malignant tumors, but the mechanism is still unclear. We aimed to detect BMPER expression in ovarian epithelial tumor tissues and its effects on their biological behaviors, as well as to elucidate the possible mechanism. Methods:...

journal_title：BioMed research international

authors： Xi Y,Nie X,Wang J,Gao L,Lin B

更新日期：2020-03-24 00:00:00

abstract：:Volatiles emitted by the host's food would be the first signals used by parasitoids in the host location process and are thought to play an important role in host habitat location. In this study, the olfactory responses of Theocolax elegans (Westwood), a Pteromalid wasp that parasitizes immature stages of stored-produ...

journal_title：BioMed research international

authors： Germinara GS,De Cristofaro A,Rotundo G

更新日期：2016-01-01 00:00:00

abstract：:ADP-glucose pyrophosphorylase (AGPase) is the first rate limiting enzyme of starch biosynthesis pathway and has been exploited as the target for greater starch yield in several plants. The structure-function analysis and substrate binding specificity of AGPase have provided enormous potential for understanding the rol...

journal_title：BioMed research international

authors： Sarma K,Sen P,Barooah M,Choudhury MD,Roychoudhury S,Modi MK

更新日期：2014-01-01 00:00:00

abstract：:Energy dispersive X-ray spectroscopy microanalysis (EDX), scanning electron microscopy (SEM), and Archimedes' Principle were used to determine the characteristics of inorganic filler particles in five dental alginates, including Cavex ColorChange (C), Hydrogum 5 (H5), Hydrogum (H), Orthoprint (O), and Jeltrate Plus (J...

journal_title：BioMed research international

authors： Guiraldo RD,Berger SB,Consani RL,Consani S,de Carvalho RV,Lopes MB,Meneghel LL,da Silva FB,Sinhoreti MA

更新日期：2014-01-01 00:00:00

abstract：:Mycobacterium bovis causes classic bovine tuberculosis, a zoonosis which is still a concern in Africa. Biofilm forming ability of two Mycobacterium bovis strains was assessed on coupons of cement, ceramic, or stainless steel in three different microbiological media at 37°C with agitation for 2, 3, or 4 weeks to determ...

journal_title：BioMed research international

authors： Adetunji VO,Kehinde AO,Bolatito OK,Chen J

更新日期：2014-01-01 00:00:00

abstract：:Periodontitis is an inflammatory disease involving complex interactions between oral microorganisms and the host immune response. Understanding the structure of the microbiota community associated with periodontitis is essential for improving classifications and diagnoses of various types of periodontal diseases and w...

journal_title：BioMed research international

authors： Chen WP,Chang SH,Tang CY,Liou ML,Tsai SJ,Lin YL

更新日期：2018-11-15 00:00:00

abstract：:The interaction of patulin with human serum albumin (HSA) was studied in vitro under normal physiological conditions. The study was performed using fluorescence, ultraviolet-visible spectroscopy (UV-Vis), circular dichroism (CD), atomic force microscopy (AFM), and molecular modeling techniques. The quenching mechanism...

journal_title：BioMed research international

authors： Yuqin L,Guirong Y,Zhen Y,Caihong L,Baoxiu J,Jiao C,Yurong G

更新日期：2014-01-01 00:00:00

abstract：:Preoperative 5-fluorouracil- (5-FU-) based chemoradiotherapy is a standard treatment for locally advanced colorectal cancer (CRC). However, the effect of 5-FU-based chemoradiotherapy on CRC is limited due to the development of chemoradiation resistance (CRR), and the molecular mechanisms underlying this resistance are...

journal_title：BioMed research international

authors： Xiong W,Ai YQ,Li YF,Ye Q,Chen ZT,Qin JY,Liu QY,Wang H,Ju YH,Li WH,Li YF

更新日期：2017-01-01 00:00:00

abstract：:Our previous studies have demonstrated that diabetes-induced oxidative stress alters homeostasis of retinal nerve growth factor (NGF) resulting in accumulation of its precursor, proNGF, at the expense of NGF which plays a critical role in preserving neuronal and retinal function. This imbalance coincided with retinal ...

journal_title：BioMed research international

authors： Mysona BA,Matragoon S,Stephens M,Mohamed IN,Farooq A,Bartasis ML,Fouda AY,Shanab AY,Espinosa-Heidmann DG,El-Remessy AB

更新日期：2015-01-01 00:00:00

abstract：:Gastric cancer is one of the most common cancers and the efficient therapeutic methods are limited. Further study of the exact molecular mechanism of gastric cancer to develop novel targeted therapies is necessary and urgent. We herein systematically examined that miR-204 suppressed both proliferation and metastasis o...

journal_title：BioMed research international

authors： Yuan X,Wang S,Liu M,Lu Z,Zhan Y,Wang W,Xu AM

更新日期：2017-01-01 00:00:00

abstract：:Objectives. Osteopontin (OPN) is overexpressed in breast cancers, while its clinical and prognostic significance remained unclear. This study aimed to assess the prognostic value of OPN, especially its splice variants, in breast cancers. Methods. Data were extracted from eligible studies concerning the OPN and OPN-c e...

journal_title：BioMed research international

authors： Hao C,Wang Z,Gu Y,Jiang WG,Cheng S

更新日期：2016-01-01 00:00:00

abstract：:Transient receptor potential polycystic 2 (TRPP2) exerts vital roles in various types of cancer; however, its underlying mechanisms remain largely unknown. This study is aimed at investigating whether knockdown of TRPP2 affected the AMP-activated protein kinase (AMPK)/acetyl-CoA carboxylase (ACC) signaling pathway and...

journal_title：BioMed research international

authors： Li K,Chen L,Lin Z,Zhu J,Fang Y,Du J,Shen B,Wu K,Liu Y

更新日期：2020-11-14 00:00:00

abstract：:Traumatic brain injury (TBI) leads to important and deleterious neuroinflammation, as evidenced by indicators such as edema, cytokine production, induction of nitric oxide synthase, and leukocyte infiltration. After TBI, cerebral vascular endothelial cells play a crucial role in the pathogenesis of inflammation. In ou...

journal_title：BioMed research international

authors： Wang KW,Wang HK,Chen HJ,Liliang PC,Liang CL,Tsai YD,Cho CL,Lu K

更新日期：2014-01-01 00:00:00

abstract：Background:Lung cancer is the leading cause of death worldwide. The treatment choice for advanced stage of lung cancer may depend on histotype, performance status (PS), age, and comorbidities. In the present study, we focused on the effect of metronomic vinorelbine treatment in elderly patients with advanced unresectab...

journal_title：BioMed research international

authors： D'Ascanio M,Pezzuto A,Fiorentino C,Sposato B,Bruno P,Grieco A,Mancini R,Ricci A

更新日期：2018-08-27 00:00:00

abstract：:Puffer fishes were collected from the central sea in Vietnam from spring to summer season. The eggs were incubated in MRS broth that was used to test the toxicity in mice and isolate the lactic acid bacteria community that could produce tetrodotoxin (TTX). Thin layer chromatography (TLC) and high performance lipid chr...

journal_title：BioMed research international

authors： Nguyen TH,Nguyen HN,Nghe DV,Nguyen KH

更新日期：2015-01-01 00:00:00

abstract：:Erythrocytes deformation is one of the exciting properties of erythrocytes. It is still under investigation by many of the researchers in different disciplines. The clinicians and researchers are still looking for a simple and efficient method to monitor and tracking the erythrocytes deformation. This research article...

journal_title：BioMed research international

authors： Elblbesy MA

更新日期：2018-10-24 00:00:00

abstract：:It is challenging and inspiring for us to achieve high spatiotemporal resolutions in dynamic cardiac magnetic resonance imaging (MRI). In this paper, we introduce two novel models and algorithms to reconstruct dynamic cardiac MRI data from under-sampled k - t space data. In contrast to classical low-rank and sparse mo...

journal_title：BioMed research international

authors： Xiu X,Kong L

更新日期：2015-01-01 00:00:00

abstract：:Subtle perturbations in intraglomerular VEGF/VEGFR-2 signaling or in the influencing microenvironment can profoundly affect renal function, resulting in the apparently paradoxical observation that VEGF blockade attenuates proteinuria development in experimental diabetes despite exerting the opposite effect under other...

journal_title：BioMed research international

authors： Advani A,Connelly KA,Advani SL,Thai K,Zhang Y,Kelly DJ,Gilbert RE

更新日期：2013-01-01 00:00:00

abstract：AIM:To evaluate the impact of SPARC on female sexual function. METHODS:151 women with a mean age of 60 ± 11.90 and SUI had a complete urodynamic investigation and underwent SPARC operation. 98 women completed the validated female sexual function index questionnaire (FSFI) at baseline and 94 women at follow-up. A minim...

journal_title：BioMed research international

authors： Al-Ali BM,Shamloul R,Hutterer GC,Puchwein E,Pummer K,Avian A,Primus G

更新日期：2013-01-01 00:00:00

abstract：:Variations in human genome (e.g., single nucleotide polymorphisms, SNPs) may be associated with hereditary diseases, their complications, comorbidities, and drug responses. Using Web service SNP_TATA_Comparator presented in our previous paper, here we analyzed immediate surroundings of known SNP markers of diseases an...

journal_title：BioMed research international

authors： Ponomarenko P,Rasskazov D,Suslov V,Sharypova E,Savinkova L,Podkolodnaya O,Podkolodny NL,Tverdokhleb NN,Chadaeva I,Ponomarenko M,Kolchanov N

更新日期：2016-01-01 00:00:00

abstract：:Estimation of the spread and advancement of Plasmodium falciparum artemisinin-resistant parasites can be done by probing polymorphisms in the kelch (Pfk13) domain (a validated molecular marker). This study aimed to provide baseline information for future artemisinin surveillance by analyzing the k13-propeller domain i...

journal_title：BioMed research international

authors： Rana R,Ranjit M,Bal M,Khuntia HK,Pati S,Krishna S,Das A

更新日期：2020-03-15 00:00:00

abstract：:Toll-like receptors (TLRs) play a key role in the innate immune response to numerous pathogens, including Acanthamoeba spp. The aim of this study was to determine the expression of TLR2 and TLR4 in the eyes of mice following intranasal infection with Acanthamoeba spp. in relation to the host's immunological status. Am...

journal_title：BioMed research international

authors： Kot K,Kosik-Bogacka D,Łanocha-Arendarczyk N,Wojtkowiak-Giera A,Kolasa-Wołosiuk A

更新日期：2019-06-12 00:00:00

abstract：:This study was performed to assess the efficacy and safety of a topical diclofenac solution in patients with knee osteoarthritis (OA). PubMed, Embase, Cochrane Library, Web of Science, and Scopus databases were searched for randomized controlled trials until June 2020. The WOMAC pain, stiffness, physical function subs...

journal_title：BioMed research international

authors： Ling T,Li JJ,Xu RJ,Wang B,Ge WH

更新日期：2020-11-24 00:00:00

abstract：:The intra- and extracellular accumulation of misfolded and aggregated amyloid proteins is a common feature in several neurodegenerative diseases, which is thought to play a major role in disease severity and progression. The principal machineries maintaining proteostasis are the ubiquitin proteasomal and lysosomal aut...

journal_title：BioMed research international

authors： Maiti P,Manna J,Veleri S,Frautschy S

更新日期：2014-01-01 00:00:00

abstract：:Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general population. We searc...

journal_title：BioMed research international

authors： Wang P,Wang J,Ma J,Jin G,Guan X

更新日期：2017-01-01 00:00:00

abstract：Results:The VMAT plans showed superior to PTV dose conformity index (CI), homogeneity index (HI), protection of the ipsilateral lung, monitor units (MUs), and maximum dose (Dmax) to the contralateral breast compared with TSP and 9FIMRT plans. The TSP provided better protection for Dmean of the heart and left ventricle ...

journal_title：BioMed research international

authors： Hu J,Han G,Lei Y,Xu X,Ge W,Ruan C,Chang S,Zhang A,Li X

更新日期：2020-03-26 00:00:00

abstract：:Ampelopsis brevipedunculata (Maxim.) Trautv. (AB), a traditional East Asian medicine, exhibits protective effects against several inflammatory diseases. Our search for an inhibitor of IL-6-induced JAK2/STAT3 activation revealed that AB ethanolic extract (ABE) had a significant inhibitory effect on IL-6-induced STAT3 e...

journal_title：BioMed research international

authors： Jang HJ,Lee SJ,Lim HJ,Jung K,Lee S,Park CS,Lee SW,Rho MC

更新日期：2018-06-10 00:00:00

abstract：:Integrin αIIbβ3 plays a crucial role in the process of platelet aggregation. Three integrin αIIbβ3 antagonists (abciximab, eptifibatide, and tirofiban) have been approved by FDA for clinical use. Unfortunately, they all showed severe side effects such as thrombocytopenia and bleeding risk. Thus, researches on the deve...

journal_title：BioMed research international

authors： Ding X,Liu TD,Xie ZL,Zhao Q,Cao Y,Liu XD,Wang CH,Gamariel RR,Ming X,Li ZY,Kong Y

更新日期：2016-01-01 00:00:00