Abstract：
PURPOSE:The aim of this short communication is to outline our experience in policies and processes of a nuclear medicine service during the COVID-19 outbreak in Singapore. METHODS:We describe the key considerations of policies and processes that have been implemented in our nuclear medicine service since the first case of COVID-19 was confirmed in Singapore General Hospital on 23 January 2020, up to the present time. RESULTS:Infection control, screening of patients and visitors, segregation of risk groups, segregation of staff and service continuity plans, communication and staff welfare, using electronic platforms for multi-disciplinary meetings and tele-reporting are discussed. CONCLUSION:Since our hospital received the first patient with COVID-19 in Singapore, our centre has managed 16 COVID-19 cases to date. There has not been any healthcare worker in our institution who has contracted COVID-19 through patient contact. We have highlighted for discussion some of the policies and processes to prepare a nuclear medicine service for the COVID-19 threat.
journal_name
Eur J Nucl Med Mol Imagingauthors
Lam WW,Loke KS,Wong WY,Ng DCdoi
10.1007/s00259-020-04790-2subject
Has Abstractpub_date
2020-07-01 00:00:00pages
1645-1648issue
7eissn
1619-7070issn
1619-7089pii
10.1007/s00259-020-04790-2journal_volume
47pub_type
杂志文章abstract：PURPOSE:To examine the diagnostic performance of (18)F-fluorothymidine (FLT) PET/CT in primary and metastatic lymph node colorectal cancer foci in comparison with (18)F-fluorodeoxyglucose (FDG) PET/CT. METHODS:The study population comprised 28 patients with 30 newly diagnosed colorectal cancers who underwent surgical ...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-013-2424-9
更新日期：2013-08-01 00:00:00
abstract：PURPOSE:Artificial neural networks (ANN) might help to diagnose coronary artery disease. This study aimed to determine whether the diagnostic accuracy of an ANN-based diagnostic system and conventional quantitation are comparable. METHODS:The ANN was trained to classify potentially abnormal areas as true or false base...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章,多中心研究
doi：10.1007/s00259-017-3834-x
更新日期：2017-12-01 00:00:00
abstract：PURPOSE:Age-related values of (123)I-orthoiodohippurate (OIH) single kidney clearance rate (Cl) were estimated in a large cohort of likely normal children aged between 0 and 18 years. METHODS:Among 4,111 children examined in the past 10 years, 917 were selected with the following inclusion criteria: (a) mild ultrasono...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-006-0074-x
更新日期：2006-12-01 00:00:00
abstract：:The goal of this study was to perform a systematic, semi-quantitative analysis of limbic perfusion in patients with Alzheimer's disease (AD) using coregistered single-photon emission tomography (SPET) images aligned to magnetic resonance (MR) images. Limbic perfusion in 40 patients with mild to moderate AD was compare...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 临床试验,杂志文章
doi：10.1007/s00259-002-0816-3
更新日期：2002-07-01 00:00:00
abstract：PURPOSE:A pilot study was performed in patients with recurrent back pain after spinal fusion surgery to evaluate the ability of (18)F-NaF PET/CT imaging to correctly identify those requiring surgical intervention and to locate a site amenable to surgical intervention. METHODS:In this prospective study 22 patients with...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 临床试验,杂志文章
doi：10.1007/s00259-012-2196-7
更新日期：2012-11-01 00:00:00
abstract：PURPOSE:18-fluorodeoxyglucose positron emission tomography combined with computed tomography (FDG-PET/CT) is increasingly used to evaluate treatment response in head and neck squamous cell carcinoma (HNSCC). This analysis assessed the diagnostic value of FDG-PET/CT in detecting nodal disease within 6 months after treat...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章,meta分析
doi：10.1007/s00259-018-3978-3
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:We investigated the performance of the Inveon small-animal PET/SPECT/CT system and compared the imaging capabilities of the SPECT and PET components. METHODS:For SPECT, the energy resolution, tomographic spatial resolution and system sensitivity were evaluated with a (99m)Tc solution using a single pinhole col...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-010-1683-y
更新日期：2011-04-01 00:00:00
abstract：PURPOSE:(32)P-chromic phosphate colloid treatments of astrocytoma and craniopharyngioma cystic brain tumours in paediatric patients are conventionally based on a sphere model under the assumption of uniform uptake. The aims of this study were to determine the distribution of the absorbed dose delivered by (32)P on a pa...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-013-2451-6
更新日期：2013-10-01 00:00:00
abstract：PURPOSE:To determine clinical predictors and accuracy of (123)I-FP-CIT SPECT imaging in the differentiation of drug-induced parkinsonism (DIP) and Parkinson's disease (PD). METHODS:Several clinical features and (123)I-FP-CIT SPECT images in 32 patients with DIP, 25 patients with PD unmasked by antidopaminergic drugs (...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-009-1289-4
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:To evaluate the reproducibility of the combination of hybrid PET/MRI and the (68)Ga-PSMA-11 tracer in depicting lymph node (LN) and bone metastases of prostate cancer (PC) in comparison with that of PET/CT. MATERIALS AND METHODS:A retrospective analysis of 26 patients who were subjected to (68)Ga-PSMA PET/CTlo...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-015-3206-3
更新日期：2016-01-01 00:00:00
abstract：:Breast cancer is associated with increased glucose consumption and can therefore be visualised with the glucose analogue [(18)F]2-deoxy-2-fluoro-D-glucose (FDG) and positron emission tomography (PET). FDG uptake in the primary tumour can vary substantially, and specific tumour characteristics have been demonstrated to...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章,评审
doi：10.1007/s00259-004-1529-6
更新日期：2004-06-01 00:00:00
abstract：:Orthostatic hypotension (OH) can be present in idiopathic Parkinson's disease (IPD) as well as in atypical parkinsonian syndromes such as multiple system atrophy (MSA). According to clinical tests of sympathetic nerve function and histopathological data, OH is caused by primarily postganglionic sympathetic dysfunction...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 临床试验,杂志文章
doi：10.1007/s00259-002-1019-7
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:Here, the expression of F4/80 on the cell surface of murine macrophages was exploited to develop a novel imaging tracer that could visualize macrophages in vivo. METHODS:The immunoreactive fraction and IC50 of anti-F4/80-A3-1, conjugated with diethylenetriaminepentaacetic acid (DTPA) and radiolabelled with (11...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-015-3084-8
更新日期：2015-08-01 00:00:00
abstract：:This study was performed to prospectively investigate the impact of image fusion in resolving discrepant findings between fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) and magnetic resonance imaging (MRI) or X-ray computed tomography (CT) in patients with gynaecological cancers. Discrepant find...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 临床试验,杂志文章
doi：10.1007/s00259-003-1300-4
更新日期：2003-12-01 00:00:00
abstract：PURPOSE:According to the updated WHO classification of gliomas with its emphasis on molecular parameters, tumours with an IDH-wildtype status have a dismal prognosis. To ensure timely adjustment of treatment, demand for non-invasive prediction methods is high. 18F-FET PET has been shown to be an important diagnostic to...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-019-04477-3
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:The aim of this study was to define the impact of the presence of axillary nodal metastases on lymphatic mapping and sentinel lymph node (SLN) identification rate in patients with early breast cancer. METHODS:Two hundred and forty-six lymphatic mapping procedures were performed with both labelled nanocolloid a...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-005-1797-9
更新日期：2005-08-01 00:00:00
abstract：PURPOSE:The high failure rates in the radiotherapy (RT) target volume suggest that patients with locally advanced oesophageal cancer (LAOC) would benefit from increased total RT doses. High 2-deoxy-2-[(18)F]fluoro-D-glucose (FDG) uptake (hotspot) on pre-RT FDG positron emission tomography (PET)/CT has been reported to ...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-015-3004-y
更新日期：2015-05-01 00:00:00
abstract：:(124)I-PET/CT has a high clinical potential in patients with differentiated thyroid cancer (DTC). Two aspects deserve special mention: staging of recurrent or residual disease and pretherapy dosimetry. Used in combination (124)I-PET and CT allows foci of highly specific (124)I uptake to be localized with a low radiati...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章,评审
doi：10.1007/s00259-011-1773-5
更新日期：2011-05-01 00:00:00
abstract：PURPOSE:In vivo Alzheimer's disease (AD) biomarkers for tau pathology are cerebrospinal fluid (CSF) phosphorylated tau (p-tau) and [18F]flortaucipir positron emission tomography (PET). Our aim was to assess associations between CSF p-tau with [18F]flortaucipir PET and the associations of both tau biomarkers with cognit...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-020-04758-2
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:Quantitative image reconstruction in positron emission tomography (PET) requires an accurate attenuation map of the object under study for the purpose of attenuation correction. Current dual-modality PET/CT systems offer significant advantages over stand-alone PET, including decreased overall scanning time and ...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-006-0086-6
更新日期：2006-11-01 00:00:00
abstract：INTRODUCTION:Positron emission tomography (PET) is a fully quantitative technology for imaging metabolic pathways and dynamic processes in vivo. Attenuation correction of raw PET data is a prerequisite for quantification and is typically based on separate transmission measurements. In PET/CT attenuation correction, how...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章,评审
doi：10.1007/s00259-008-1007-7
更新日期：2009-03-01 00:00:00
abstract：PURPOSE:This study investigated the potential of deep convolutional neural networks (CNN) for automatic classification of FP-CIT SPECT in multi-site or multi-camera settings with variable image characteristics. METHODS:The study included FP-CIT SPECT of 645 subjects from the Parkinson's Progression Marker Initiative (...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-019-04502-5
更新日期：2019-12-01 00:00:00
abstract：PURPOSE:Radioligand therapy (RLT) using Lutetium-177 labeled PSMA-617 (Lu-PSMA) ligand is a new therapeutic option for salvage therapy in heavily pretreated patients with metastatic castration resistant prostate cancer. The aim of this retrospective study was to analyze response in patients receiving 3 cycles of Lu-PSM...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-017-3877-z
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:The washout rate (WR) has been used in (123)I-metaiodobenzylguanidine (MIBG) imaging to evaluate cardiac sympathetic innervation. However, WR varies depending on the time between the early and late MIBG scans. Late scans are performed at either 3 or 4 hours after injection of MIBG. The aim of this study was to ...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-015-3173-8
更新日期：2016-02-01 00:00:00
abstract：PURPOSE:Myocardial blood flow (MBF) measurement using positron emission tomography (PET) from the washout rate of (15)O-water is theoretically independent of tissue attenuation. The aim of this study was to evaluate the impact of not using attenuation correction in the assessment of coronary endothelial function and my...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-015-3163-x
更新日期：2016-02-01 00:00:00
abstract：PURPOSE:This meta-analysis summarized the accuracy of stress myocardial perfusion scintigraphy (MPS) and stress echocardiography for the diagnosis of coronary artery disease (CAD) in patients with arterial hypertension. METHODS:We searched for studies in which stress MPS or stress echocardiography were performed to de...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章,meta分析
doi：10.1007/s00259-011-1891-0
更新日期：2011-11-01 00:00:00
abstract：:This study assessed the clinical usefulness of a new technetium-99m labelled somatostatin analogue from the standpoint of oncological diagnostics. The study group comprised 40 patients in whom malignant neoplasms (32 primary and 8 metastatic) had been diagnosed. Among the primary tumours there were 21 cases of lung ca...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 临床试验,杂志文章
doi：10.1007/s00259-003-1254-6
更新日期：2003-10-01 00:00:00
abstract：PURPOSE:Investigate whether 18F-FDG PET-CT has the potential to predict the major pathologic response (MPR) to neoadjuvant sintilimab in resectable NSCLC patients, and the potential of sifting patients who probably benefit from immunotherapy. METHODS:Treatment-naive patients with resectable NSCLC (stage IA-IIIB) recei...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-020-04711-3
更新日期：2020-05-01 00:00:00
abstract：:Radionuclide imaging of cardiac function represents a number of well-validated techniques for accurate determination of right (RV) and left ventricular (LV) ejection fraction (EF) and LV volumes. These first European guidelines give recommendations for how and when to use first-pass and equilibrium radionuclide ventri...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章,实务指引
doi：10.1007/s00259-007-0694-9
更新日期：2008-04-01 00:00:00
abstract：PURPOSE:While methods for imaging tumor hypoxia with positron emission tomography (PET) have been developed, optimal methods for interpreting and utilizing these datasets in the clinic remain unclear. In this study, we analyzed hypoxia PET images of head and neck cancer patients and compared imaging metrics with human ...
journal_title：European journal of nuclear medicine and molecular imaging
pub_type： 杂志文章
doi：10.1007/s00259-015-3247-7
更新日期：2016-04-01 00:00:00
