当前位置： SCI文献检索 > EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING期刊下所有文献 > Clinical usefulness of 99mTc-EDDA/HYNIC-TOC scintigraphy in oncological diagnostics: a preliminary communication.

Clinical usefulness of 99mTc-EDDA/HYNIC-TOC scintigraphy in oncological diagnostics: a preliminary communication.

Abstract：

:This study assessed the clinical usefulness of a new technetium-99m labelled somatostatin analogue from the standpoint of oncological diagnostics. The study group comprised 40 patients in whom malignant neoplasms (32 primary and 8 metastatic) had been diagnosed. Among the primary tumours there were 21 cases of lung cancer (2 small cell and 19 non-small cell), seven pituitary adenomas (five hormonally active and two inactive), one liposarcoma, two carcinoids and one breast carcinoma. The metastatic tumours consisted of three malignant melanomas, one phaeochromocytoma, one prostatic cancer, one leiomyosarcoma, one pancreatic carcinoma ectopically secreting ACTH and one carcinoid of the thymus. The radiopharmaceutical 99mTc-EDDA/HYNIC-Tyr3-octreotide was administered i.v. at an activity of 740-925 MBq. The imaging comprised a whole-body scan and a single-photon emission tomography acquisition. Positive scintigrams were obtained in all cases of small cell and non-small cell lung cancer, four out of five hormonally active pituitary adenomas, one out of two cases of carcinoid, the liposarcoma and the breast cancer. Neoplastic metastases were visualised in two out of three patients with melanoma and in patients with phaeochromocytoma, ACTH-secreting pancreatic carcinoma and thymic carcinoid. Scintigrams were negative in both hormonally inactive pituitary adenomas, in one case of metastatic malignant melanoma, in the leiomyosarcoma and in the case of metastasis from prostatic carcinoma. The results of this pilot study indicate that 99mTc-EDDA/HYNIC-TOC is a potentially useful radiopharmaceutical for imaging of a wide range of primary and metastatic tumours. Special attention should be paid to the successful imaging of all cases of non-small cell lung cancer.

journal_name

Eur J Nucl Med Mol Imaging

journal_title

European journal of nuclear medicine and molecular imaging

authors

Płachcińska A,Mikołajczak R,Maecke HR,Młodkowska E,Kunert-Radek J,Michalski A,Rzeszutek K,Kozak J,Kuśmierek J

doi

10.1007/s00259-003-1254-6

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

1402-6

issue

10

eissn

1619-7070

issn

1619-7089

journal_volume

30

pub_type

临床试验,杂志文章

相关文献

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING文献大全
  • Direct comparison of (68)Ga-DOTA-TOC and (18)F-FDG PET/CT in the follow-up of patients with neuroendocrine tumour treated with the first full peptide receptor radionuclide therapy cycle.

    abstract：PURPOSE:To determine the value of (68)Ga-DOTA-TOC and (18)F-FDG PET/CT for initial and follow-up evaluation of patients with neuroendocrine tumour (NET) treated with peptide receptor radionuclide therapy (PRRT). METHODS:We evaluated 66 patients who had histologically proven NET and underwent both PRRT and three combin...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-016-3328-2

    authors： Nilica B,Waitz D,Stevanovic V,Uprimny C,Kendler D,Buxbaum S,Warwitz B,Gerardo L,Henninger B,Virgolini I,Rodrigues M

    更新日期：2016-08-01 00:00:00

  • PET-MR image fusion in soft tissue sarcoma: accuracy, reliability and practicality of interactive point-based and automated mutual information techniques.

    abstract：:The fusion of functional positron emission tomography (PET) data with anatomical magnetic resonance (MR) or computed tomography images, using a variety of interactive and automated techniques, is becoming commonplace, with the technique of choice dependent on the specific application. The case of PET-MR image fusion i...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00259-002-0994-z

    authors： Somer EJ,Marsden PK,Benatar NA,Goodey J,O'Doherty MJ,Smith MA

    更新日期：2003-01-01 00:00:00

  • Automated analysis of small animal PET studies through deformable registration to an atlas.

    abstract：PURPOSE:This work aims to develop a methodology for automated atlas-guided analysis of small animal positron emission tomography (PET) data through deformable registration to an anatomical mouse model. METHODS:A non-rigid registration technique is used to put into correspondence relevant anatomical regions of rodent C...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-012-2188-7

    authors： Gutierrez DF,Zaidi H

    更新日期：2012-11-01 00:00:00

  • Diagnostic value of kinetic analysis using dynamic FDG PET in immunocompetent patients with primary CNS lymphoma.

    abstract：PURPOSE:The purpose of this study was to investigate the accumulation of FDG in immunocompetent patients with primary central nervous system (CNS) lymphoma using qualitative and quantitative PET images and to compare baseline with follow-up PET after therapy. METHODS:Twelve immunocompetent patients with CNS lymphoma w...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-006-0153-z

    authors： Nishiyama Y,Yamamoto Y,Monden T,Sasakawa Y,Kawai N,Satoh K,Ohkawa M

    更新日期：2007-01-01 00:00:00

  • Validation of the dual-table autoradiographic method to quantify two sequential rCBFs in a single SPET session with N-isopropyl-[123I] p-iodoamphetamine.

    abstract：:We evaluated an autoradiographic (ARG) method to calculate regional cerebral blood flow (rCBF) sequentially before and after an acetazolamide (ACZ) challenge in a single session of single-photon emission tomography (SPET) with two injections of N-isopropyl-[(123)I] p-iodoamphetamine (IMP). The method uses a table look...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00259-003-1180-7

    authors： Nishizawa S,Iida H,Tsuchida T,Ito H,Konishi J,Yonekura Y

    更新日期：2003-07-01 00:00:00

  • Non-invasive imaging of cardiac transgene expression with PET: comparison of the human sodium/iodide symporter gene and HSV1-tk as the reporter gene.

    abstract：PURPOSE:Genes encoding for intracellular enzymes or transmembrane proteins are suitable as reporters, but may differ in terms of applicability for cardiac imaging. The aim of this study was to compare the human sodium iodide symporter gene (hNIS) with the herpes simplex virus type 1 thymidine kinase gene (HSV1-tk) as t...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-005-1854-4

    authors： Miyagawa M,Anton M,Wagner B,Haubner R,Souvatzoglou M,Gansbacher B,Schwaiger M,Bengel FM

    更新日期：2005-09-01 00:00:00

  • 18F-FDG PET in drug-resistant epilepsy due to focal cortical dysplasia type 2: additional value of electroclinical data and coregistration with MRI.

    abstract：PURPOSE:To assess the localizing value of 18F-FDG PET in patients operated on for drug-resistant epilepsy due to focal cortical dysplasia type 2 (FCD2). METHODS:We analysed 18F-FDG PET scans from 103 consecutive patients (52 males, 7-65 years old) with histologically proven FCD2. PET and MRI data were first reviewed b...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-018-3994-3

    authors： Desarnaud S,Mellerio C,Semah F,Laurent A,Landre E,Devaux B,Chiron C,Lebon V,Chassoux F

    更新日期：2018-07-01 00:00:00

  • Are [O-methyl-11C]derivatives of ICI 89,406 beta1-adrenoceptor selective radioligands suitable for PET?

    abstract：PURPOSE:Radioligand binding studies show that beta(1)-adrenoceptor (beta(1)-AR) density may be reduced in heart disease without down regulation of beta(2)-ARs. Radioligands are available for measuring total beta-AR density non-invasively with clinical positron emission tomography (PET) but none are selective for beta(1...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-007-0553-8

    authors： Law MP,Wagner S,Kopka K,Pike VW,Schober O,Schäfers M

    更新日期：2008-01-01 00:00:00

  • Improved kinetic stability of DTPA- dGlu as compared with conventional monofunctional DTPA in chelating indium and yttrium: preclinical and initial clinical evaluation of radiometal labelled minigastrin derivatives.

    abstract：:The development of monofunctional DTPA derivatives has been a major breakthrough in the labelling of proteins or peptides with a variety of radiometals. Although this methodology is simple and useful for indium-111 labelling, the stability of these conjugates is too low for most therapeutic nuclides. Cyclic chelators,...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00259-003-1178-1

    authors： Béhé M,Becker W,Gotthardt M,Angerstein C,Behr TM

    更新日期：2003-08-01 00:00:00

  • Favourable course of disease after incomplete remission on (131)I therapy in children with pulmonary metastases of papillary thyroid carcinoma: 10 years follow-up.

    abstract：PURPOSE:The aim of this study is to report on a collective of 20 children from Belarus who had developed papillary thyroid carcinoma with pulmonary metastases after the Chernobyl disaster. In all children fractionated radioiodine therapy (RIT) was ceased before achieving complete remission due to a lack of further effe...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00259-010-1669-9

    authors： Biko J,Reiners C,Kreissl MC,Verburg FA,Demidchik Y,Drozd V

    更新日期：2011-04-01 00:00:00

  • Prognostic value of lymph node-to-primary tumor standardized uptake value ratio in endometrioid endometrial carcinoma.

    abstract：PURPOSE:To determine whether the relative metabolic activity of pelvic or para-aortic LN compared with that of primary tumor measured by preoperative [18F]FDG PET/CT scan has prognostic value in patients with endometrioid endometrial carcinoma. METHODS:We retrospectively reviewed patients with endometrioid endometrial...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-017-3805-2

    authors： Chung HH,Cheon GJ,Kim JW,Park NH,Song YS

    更新日期：2018-01-01 00:00:00

  • Automated assessment of FDG-PET for differential diagnosis in patients with neurodegenerative disorders.

    abstract：PURPOSE:To review literature until November 2015 and reach a consensus on whether automatic semi-quantification of brain FDG-PET is useful in the clinical setting for neurodegenerative disorders. METHODS:A literature search was conducted in Medline, Embase, and Google Scholar. Papers were selected with a lower limit o...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章,评审

    doi：10.1007/s00259-018-4030-3

    authors： Nobili F,Festari C,Altomare D,Agosta F,Orini S,Van Laere K,Arbizu J,Bouwman F,Drzezga A,Nestor P,Walker Z,Boccardi M,EANM-EAN Task Force for the Prescription of FDG-PET for Dementing Neurodegenerative Disorders.

    更新日期：2018-07-01 00:00:00

  • The effect of 18F-florbetapir dose reduction on region-based classification of cortical amyloid deposition.

    abstract：UNLABELLED:There are specific dose recommendations for diagnostic amyloid PET imaging with 18F-florbetapir, but they may not apply to research studies using regional quantitative analysis. We, therefore, studied the effect of tracer dose reduction on the discriminative power of regional analysis. METHODS:Using bootstr...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-014-2842-3

    authors： Herholz K,Evans R,Anton-Rodriguez J,Hinz R,Matthews JC

    更新日期：2014-11-01 00:00:00

  • Memory-provoked rCBF-SPECT as a diagnostic tool in Alzheimer's disease?

    abstract：PURPOSE:Alzheimer's disease (AD) is a primary degenerative disease that progressively affects all brain functions, with devastating consequences for the patient, the patient's family and society. Rest regional cerebral blood flow (rCBF) could have a strategic role in differentiating between AD patients and normal contr...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-005-1874-0

    authors： Sundström T,Elgh E,Larsson A,Näsman B,Nyberg L,Riklund KA

    更新日期：2006-01-01 00:00:00

  • Facing a disruptive threat: how can a nuclear medicine service be prepared for the coronavirus outbreak 2020?

    abstract：PURPOSE:The aim of this short communication is to outline our experience in policies and processes of a nuclear medicine service during the COVID-19 outbreak in Singapore. METHODS:We describe the key considerations of policies and processes that have been implemented in our nuclear medicine service since the first cas...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-020-04790-2

    authors： Lam WW,Loke KS,Wong WY,Ng DC

    更新日期：2020-07-01 00:00:00

  • Clinical response assessment on DW-MRI compared with FDG-PET/CT after neoadjuvant chemoradiotherapy in patients with oesophageal cancer.

    abstract：PURPOSE:In about 30% of patients treated with neoadjuvant chemoradiotherapy (nCRT) followed by surgical resection for locally advanced oesophageal cancer no vital tumour is found in the resection specimen. Accurate clinical response assessment is critical if deferral from surgery is considered in complete responders. O...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-020-04917-5

    authors： Vollenbrock SE,Voncken FEM,Lambregts DMJ,Maas M,Donswijk ML,Vegt E,Ter Beek LC,van Dieren JM,van Sandick JW,Aleman BMP,Beets-Tan RGH,Bartels-Rutten A

    更新日期：2021-01-01 00:00:00

  • Disseminated iodine-avid lung metastases in differentiated thyroid cancer: a challenge to 124I PET.

    abstract：AIM:This study assessed the ability of visual and quantitative 124-iodine positron emission tomography ((124)I PET) data to detect disseminated iodine-avid lung metastases (DILM) of differentiated thyroid cancer (DTC). MATERIALS AND METHODS:Using "post-therapy" 131-iodine ((131)I) whole-body scintigraphy (TxWBS) and t...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-007-0601-4

    authors： Freudenberg LS,Jentzen W,Müller SP,Bockisch A

    更新日期：2008-03-01 00:00:00

  • Should PET/CT be implemented in the routine imaging work-up of locally advanced head and neck squamous cell carcinoma? A prospective analysis.

    abstract：PURPOSE:The objective of this study was to determine the incremental staging information provided by positron emission tomography/computed tomography (PET/CT) and its impact on management plans in patients with untreated stage III-IV head and neck squamous cell carcinoma (HNSCC). METHODS:We prospectively studied, betw...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-015-3071-0

    authors： Cacicedo J,Fernandez I,Del Hoyo O,Dolado A,Gómez-Suarez J,Hortelano E,Sancho A,Pijoan JI,Alvarez J,Espinosa JM,Gaafar A,Bilbao P

    更新日期：2015-08-01 00:00:00

  • Response to neoadjuvant chemotherapy for breast cancer judged by PERCIST - multicenter study in Japan.

    abstract：PURPOSE:The purpose of this study was to evaluate therapeutic response to neoadjuvant chemotherapy (NAC) and predict breast cancer recurrence using Positron Emission Tomography Response Criteria in Solid Tumors (PERCIST). MATERIALS AND METHODS:Fifty-nine breast cancer patients underwent fluorodeoxyglucose-positron emi...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00259-018-4008-1

    authors： Kitajima K,Nakatani K,Yamaguchi K,Nakajo M,Tani A,Ishibashi M,Hosoya K,Morita T,Kinoshita T,Kaida H,Miyoshi Y

    更新日期：2018-09-01 00:00:00

  • The added value of SPECT-CT for the identification of sentinel lymph nodes in early stage oral cancer.

    abstract：PURPOSE:To assess the role of single-photon emission computed tomography with computed tomography (SPECT-CT) for the identification of sentinel lymph nodes (SLNs) in patients with early stage (T1-T2) oral cancer and a clinically negative neck (cN0). METHODS:In addition to planar lymphoscintigraphy, SPECT-CT was perfor...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-017-3613-8

    authors： den Toom IJ,van Schie A,van Weert S,Karagozoglu KH,Bloemena E,Hoekstra OS,de Bree R

    更新日期：2017-06-01 00:00:00

  • Altered serotonin transporter availability in patients with multiple sclerosis.

    abstract：PURPOSE:Modulation of the immune system by the CNS may involve serotonergic regulation via the brain serotonin transporters (SERT). This regulation may be disturbed in patients with CNS disorders including multiple sclerosis (MS). Central serotonergic mechanisms have not been investigated in MS by in vivo imaging. The ...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-013-2636-z

    authors： Hesse S,Moeller F,Petroff D,Lobsien D,Luthardt J,Regenthal R,Becker GA,Patt M,Thomae E,Seese A,Meyer PM,Bergh FT,Sabri O

    更新日期：2014-05-01 00:00:00

  • Whole-body voxel-based internal dosimetry using deep learning.

    abstract：PURPOSE:In the era of precision medicine, patient-specific dose calculation using Monte Carlo (MC) simulations is deemed the gold standard technique for risk-benefit analysis of radiation hazards and correlation with patient outcome. Hence, we propose a novel method to perform whole-body personalized organ-level dosime...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-020-05013-4

    authors： Akhavanallaf A,Shiri I,Arabi H,Zaidi H

    更新日期：2020-09-01 00:00:00

  • Radiomics in nuclear medicine: robustness, reproducibility, standardization, and how to avoid data analysis traps and replication crisis.

    abstract：:Radiomics in nuclear medicine is rapidly expanding. Reproducibility of radiomics studies in multicentre settings is an important criterion for clinical translation. We therefore performed a meta-analysis to investigate reproducibility of radiomics biomarkers in PET imaging and to obtain quantitative information regard...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章,评审

    doi：10.1007/s00259-019-04391-8

    authors： Zwanenburg A

    更新日期：2019-12-01 00:00:00

  • [N-methyl 11C]meta-Hydroxyephedrine positron emission tomography in Parkinson's disease and multiple system atrophy.

    abstract：:Orthostatic hypotension (OH) can be present in idiopathic Parkinson's disease (IPD) as well as in atypical parkinsonian syndromes such as multiple system atrophy (MSA). According to clinical tests of sympathetic nerve function and histopathological data, OH is caused by primarily postganglionic sympathetic dysfunction...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00259-002-1019-7

    authors： Berding G,Schrader CH,Peschel T,van den Hoff J,Kolbe H,Meyer GJ,Dengler R,Knapp WH

    更新日期：2003-01-01 00:00:00

  • The prognostic and predictive value of sstr2-immunohistochemistry and sstr2-targeted imaging in neuroendocrine tumors.

    abstract：PURPOSE:Our aim was to assess the prognostic and predictive value of somatostatin receptor 2 (sstr2) in neuroendocrine tumors (NETs). METHODS:We established a tissue microarray and imaging database from NET patients that received sstr2-targeted radiopeptide therapy with yttrium-90-DOTATOC, lutetium-177-DOTATOC or alte...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-016-3486-2

    authors： Brunner P,Jörg AC,Glatz K,Bubendorf L,Radojewski P,Umlauft M,Marincek N,Spanjol PM,Krause T,Dumont RA,Maecke HR,Müller-Brand J,Briel M,Schmitt A,Perren A,Walter MA

    更新日期：2017-03-01 00:00:00

  • Value of (18)F-FDG PET/CT for therapeutic assessment of patients with polymyalgia rheumatica receiving tocilizumab as first-line treatment.

    abstract：PURPOSE:To evaluate the use of (18)F-FDG PET/CT for the assessment of tocilizumab (TCZ) as first-line treatment in patients with polymyalgia rheumatica (PMR). METHODS:Patients with PMR were prospectively enrolled in a multicentre clinical trial assessing TCZ therapy (the TENOR trial). The patients underwent FDG PET/CT...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00259-015-3287-z

    authors： Palard-Novello X,Querellou S,Gouillou M,Saraux A,Marhadour T,Garrigues F,Abgral R,Salaün PY,Devauchelle-Pensec V

    更新日期：2016-04-01 00:00:00

  • A critical review of radiotracers in the positron emission tomography imaging of traumatic brain injury: FDG, tau, and amyloid imaging in mild traumatic brain injury and chronic traumatic encephalopathy.

    abstract：PURPOSE:Positron emission tomography (PET) has been widely utilized in the study of traumatic brain injury (TBI) for decades. While most applications of PET have attempted to assess neuronal function after TBI, more recently, novel radiotracers have sought to image biomarkers in the context of TBI and chronic traumatic...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章,评审

    doi：10.1007/s00259-020-04926-4

    authors： Ayubcha C,Revheim ME,Newberg A,Moghbel M,Rojulpote C,Werner TJ,Alavi A

    更新日期：2021-02-01 00:00:00

  • Uptake kinetics and biodistribution of 14C-D-luciferin--a radiolabeled substrate for the firefly luciferase catalyzed bioluminescence reaction: impact on bioluminescence based reporter gene imaging.

    abstract：PURPOSE:Firefly luciferase catalyzes the oxidative decarboxylation of D: -luciferin to oxyluciferin in the presence of cofactors, producing bioluminescence. This reaction is used in optical bioluminescence-based molecular imaging approaches to detect the expression of the firefly luciferase reporter gene. Biokinetics a...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-008-0870-6

    authors： Berger F,Paulmurugan R,Bhaumik S,Gambhir SS

    更新日期：2008-12-01 00:00:00

  • Non-small-cell lung cancer resectability: diagnostic value of PET/MR.

    abstract：PURPOSE:To assess the diagnostic performance of PET/MR in patients with non-small-cell lung cancer. METHODS:Fifty consecutive consenting patients who underwent routine (18)F-FDG PET/CT for potentially radically treatable lung cancer following a staging CT scan were recruited for PET/MR imaging on the same day. Two exp...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-014-2873-9

    authors： Fraioli F,Screaton NJ,Janes SM,Win T,Menezes L,Kayani I,Syed R,Zaccagna F,O'Meara C,Barnes A,Bomanji JB,Punwani S,Groves AM

    更新日期：2015-01-01 00:00:00

  • The efficiency of 18F-FDG PET-CT for predicting the major pathologic response to the neoadjuvant PD-1 blockade in resectable non-small cell lung cancer.

    abstract：PURPOSE:Investigate whether 18F-FDG PET-CT has the potential to predict the major pathologic response (MPR) to neoadjuvant sintilimab in resectable NSCLC patients, and the potential of sifting patients who probably benefit from immunotherapy. METHODS:Treatment-naive patients with resectable NSCLC (stage IA-IIIB) recei...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-020-04711-3

    authors： Tao X,Li N,Wu N,He J,Ying J,Gao S,Wang S,Wang J,Wang Z,Ling Y,Tang W,Zhang Z

    更新日期：2020-05-01 00:00:00