Clinical applications of 124I-PET/CT in patients with differentiated thyroid cancer.

abstract：:The aim of this study was to describe the anatomical structures that show uptake of the somatostatin analogue octreotide in patients with thyroid-associated orbitopathy (TAO). The study population comprised a series of 20 TAO patients attending the out-patient thyroid clinic and 12 patients presenting head or neck tum...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kainz H,Bale R,Donnemiller E,Gabriel M,Kovacs P,Decristoforo C,Moncayo R

更新日期：2003-08-01 00:00:00

abstract：:The aim of this study was the development of a modelling approach for the analysis of the systemic kinetics of the tracer nitrogen-13 ammonia administered for dynamic liver scanning. The radioactive half-life of this tracer is 9.8 min, which limits the time span in which data are available in a positron emission tomog...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Weiss M,Roelsgaard K,Bender D,Keiding S

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess radiomics features on pre-treatment [18F]FDG positron emission tomography (PET) as potential biomarkers for response and survival in patients with metastatic colorectal cancer (mCRC). METHODS:Patients with mCRC underwent [18F]FDG PET/computed tomography (CT) prior to firs...

journal_title：European journal of nuclear medicine and molecular imaging

authors： van Helden EJ,Vacher YJL,van Wieringen WN,van Velden FHP,Verheul HMW,Hoekstra OS,Boellaard R,Menke-van der Houven van Oordt CW

更新日期：2018-12-01 00:00:00

abstract：:Physiologically increased pancreatic uptake at the head/uncinate process is observed in more than one-third of patients after injection of one of the three (68)Ga-labelled octreotide-based peptides used for somatostatin (sst) receptor (r) imaging. There are minor differences between these (68)Ga-sstr-binding peptides ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Virgolini I,Gabriel M,Kroiss A,von Guggenberg E,Prommegger R,Warwitz B,Nilica B,Roig LG,Rodrigues M,Uprimny C

更新日期：2016-10-01 00:00:00

abstract：PURPOSE:The effect of various doses of methylphenidate on the binding of [(123)I]iodobenzamide ([(123)I]IBZM) to the rat D(2) receptor was assessed using small animal SPECT. METHODS:D(2) receptor binding was measured at baseline and after pretreatment with various doses of methylphenidate. For baseline and methylpheni...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nikolaus S,Antke C,Beu M,Kley K,Wirrwar A,Huston JP,Müller HW

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:In Churg-Strauss syndrome (CSS) it is important to detect cardiac involvement, which predicts poor prognosis. This study evaluated whether (123)I-metaiodobenzylguanidine (MIBG) scintigraphy could detect cardiac damage and predict cardiac events in CSS. METHODS:(123)I-MIBG scintigraphy was performed in 28 patie...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Horiguchi Y,Morita Y,Tsurikisawa N,Akiyama K

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:In children with Hodgkin's disease and non-Hodgkin's lymphoma, the ability of (18)F-fluoro-2-deoxy-D-glucose PET/CT and conventional imaging (CI) to detect malignant lesions and predict poor lesion response to therapy was assessed and compared. METHODS:A retrospective review of findings reported on PET/CT and ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： London K,Cross S,Onikul E,Dalla-Pozza L,Howman-Giles R

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:We tested the hypothesis that lateralized hemispheric glucose metabolism may have diagnostic implications in Alzheimer's disease (AD) and mild cognitive impairment (MCI). METHODS:We performed FDG-PET/CT in 23 patients (mean age 63.7 years, range 50-78, 17 females) diagnosed with AD (n = 15) or MCI (n = 8) duri...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Segtnan EA,Majdi A,Constantinescu C,Grupe P,Gerke O,Dali HÍ,Strøm OE,Holm J,Alavi A,Sadigh-Eteghad S,Wermuth L,Hildebrandt MG,Gjedde A,Høilund-Carlsen PF

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:4-[(18)F]-ADAM is a potent serotonin transport imaging agent. We studied its toxicity in rats and radiation dosimetry in monkeys before human studies are undertaken. METHODS:Single and multiple-dosage toxicity studies were conducted in Sprague-Dawley rats. Male and female rats were injected intravenously with ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Huang YY,Ma KH,Tseng TW,Chou TK,Ng H,Mirsalis JC,Fu YK,Chu TC,Huang WS,Shiue CY

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:PET has been proven to be helpful in the delineation of gross tumour volume (GTV) for external radiation therapy in several tumour entities. The aim of this study was to determine if [(11)C]choline PET could be used to localize the carcinomatous tissue within the prostate in order to specifically target this ar...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bundschuh RA,Wendl CM,Weirich G,Eiber M,Souvatzoglou M,Treiber U,Kübler H,Maurer T,Gschwend JE,Geinitz H,Grosu AL,Ziegler SI,Krause BJ

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:PET is a powerful tool for assessing targeted therapy. Since (18)F-FDG shows a potential prognostic value in medullary thyroid carcinoma (MTC), this study evaluated (18)F-FDG PET alone and combined with morphological and biomarker evaluations as a surrogate marker of overall survival (OS) in patients with progr...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Salaun PY,Campion L,Ansquer C,Frampas E,Mathieu C,Robin P,Bournaud C,Vuillez JP,Taieb D,Rousseau C,Drui D,Mirallié E,Borson-Chazot F,Goldenberg DM,Chatal JF,Barbet J,Kraeber-Bodéré F

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:Multi-centre trials are an important part of proving the efficacy of procedures, drugs and interventions. Imaging components in such trials are becoming increasingly common; however, without sufficient control measures the usefulness of these data can be compromised. This paper describes a framework for perform...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Dickson JC,Tossici-Bolt L,Sera T,de Nijs R,Booij J,Bagnara MC,Seese A,Koulibaly PM,Akdemir UO,Jonsson C,Koole M,Raith M,Lonsdale MN,George J,Zito F,Tatsch K

更新日期：2012-01-01 00:00:00

abstract：:We present a system of image co-registration and its validation in phantom and volunteer studies. The system co-registered images via six novel non-invasive and non-radioactive external markers. The fiducial markers were attached with sponge bases on the skin surface of the phantom and the volunteers in a non-collinea...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wu TH,Wang JK,Lee JJ,Liu RS,Guo WY

更新日期：2003-06-01 00:00:00

abstract：PURPOSE:The purpose of this study was to design a fully automatic computer-assisted diagnostic system for early- and late-onset mild Alzheimer's disease (AD). METHODS:Glucose metabolic images were obtained from mild AD patients and normal controls using positron emission tomography (PET) and( 18)F-fluorodeoxyglucose (...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ishii K,Kono AK,Sasaki H,Miyamoto N,Fukuda T,Sakamoto S,Mori E

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:Modulation of the immune system by the CNS may involve serotonergic regulation via the brain serotonin transporters (SERT). This regulation may be disturbed in patients with CNS disorders including multiple sclerosis (MS). Central serotonergic mechanisms have not been investigated in MS by in vivo imaging. The ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hesse S,Moeller F,Petroff D,Lobsien D,Luthardt J,Regenthal R,Becker GA,Patt M,Thomae E,Seese A,Meyer PM,Bergh FT,Sabri O

更新日期：2014-05-01 00:00:00

abstract：:When projection data are incomplete for various technical reasons, artefacts may occur in the reconstructed images. This study examines whether an iterative reconstruction method, the ordered subsets implementation of the EM algorithm (OSEM), can improve reconstruction and minimise the artefacts compared to filtered b...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hatton RL,Hutton BF,Angelides S,Choong KK,Larcos G

更新日期：2004-06-01 00:00:00

abstract：PURPOSE:In recent decades, the use of radiopharmaceuticals in the assessment of hepatocellular carcinoma (HCC) has become established, and new findings indicate that radiolabelled choline has considerable potential in this setting. Therefore, in this study we aimed to assess the diagnostic role of (11)C-choline positro...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Lopci E,Torzilli G,Poretti D,de Neto LJ,Donadon M,Rimassa L,Lanza E,Sabongi JG,Ceriani R,Personeni N,Palmisano A,Pedicini V,Comito T,Scorsetti M,Chiti A

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:Brain serotonin 6 receptor (5-HT6) is one of the most recently identified serotonin receptors. It is a potent therapeutic target for psychiatric and neurological diseases, e.g. schizophrenia and Alzheimer's disease. Since no specific fluorinated radioligand has yet been successfully used to study this receptor ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Becker G,Colomb J,Sgambato-Faure V,Tremblay L,Billard T,Zimmer L

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To determine the metabolic profiles of the translocator protein ligands PBR102 and PBR111 in rat and human microsomes and compare their in vivo binding and metabolite uptake in the brain of non-human primates (Papio hamadryas) using PET-CT. METHODS:In vitro metabolic profiles of PBR102 and PBR111 in rat and hu...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Eberl S,Katsifis A,Peyronneau MA,Wen L,Henderson D,Loc'h C,Greguric I,Verschuer J,Pham T,Lam P,Mattner F,Mohamed A,Fulham MJ

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Although( 18)F-fluorodeoxyglucose (FDG) PET is an established imaging technique to assess brain glucose utilisation, accurate measurement of tracer concentration is confounded by the presence of partial volume effect (PVE) due to the limited spatial resolution of PET, which is particularly true in atrophic brai...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Samuraki M,Matsunari I,Chen WP,Yajima K,Yanase D,Fujikawa A,Takeda N,Nishimura S,Matsuda H,Yamada M

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:Several patients experience unexplained persistent symptoms after SARS-CoV-2 recovering. We aimed at evaluating if 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) was able to demonstrate a persistent inflammatory process. METHODS:Recovered adult COVID-19 patients, who complained unexplained persisting symptoms for ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sollini M,Ciccarelli M,Cecconi M,Aghemo A,Morelli P,Gelardi F,Chiti A

更新日期：2020-10-30 00:00:00

abstract：PURPOSE:This study proposes an automated prostate cancer (PC) lesion characterization method based on the deep neural network to determine tumor burden on 68Ga-PSMA-11 PET/CT to potentially facilitate the optimization of PSMA-directed radionuclide therapy. METHODS:We collected 68Ga-PSMA-11 PET/CT images from 193 patie...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zhao Y,Gafita A,Vollnberg B,Tetteh G,Haupt F,Afshar-Oromieh A,Menze B,Eiber M,Rominger A,Shi K

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:The objective of this study was to determine the incremental staging information provided by positron emission tomography/computed tomography (PET/CT) and its impact on management plans in patients with untreated stage III-IV head and neck squamous cell carcinoma (HNSCC). METHODS:We prospectively studied, betw...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Cacicedo J,Fernandez I,Del Hoyo O,Dolado A,Gómez-Suarez J,Hortelano E,Sancho A,Pijoan JI,Alvarez J,Espinosa JM,Gaafar A,Bilbao P

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:Levodopa and dopamine (DA) agonist therapy are two common treatments for Parkinson's disease (PD). There is controversy about the effects of these treatments on disease progression and imaging markers. Here we used multi-tracer positron emission tomography imaging and a unilateral 6-hydroxydopamine (6-OHDA) rat...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sossi V,Dinelle K,Schulzer M,Mak E,Doudet DJ,de la Fuente-Fernández R

更新日期：2010-12-01 00:00:00

abstract：PURPOSE:We investigated the potential value of (11)C-acetate (ACT) PET/CT in characterizing multiple myeloma (MM) compared with (18)F-FDG PET/CT. Bone marrow histological and whole-body (WB) MRI findings served as the reference standards. METHODS:In this prospective study, 15 untreated MM patients (10 men and 5 women,...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Lin C,Ho CL,Ng SH,Wang PN,Huang Y,Lin YC,Tang TC,Tsai SF,Rahmouni A,Yen TC

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:The goal of this study is to determine the technical accuracy of segmental perfusion parameters assessed with quantitative cardiac PET imaging in the evaluation of coronary artery disease (CAD) in patients with stable angina. METHODS:A cohort of patients who participated in the EVINCI protocol underwent an eva...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Berti V,Sciagrà R,Neglia D,Pietilä M,Scholte AJ,Nekolla S,Rouzet F,Pupi A,Knuuti J

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:Tau accumulation is a core pathologic change in various neurodegenerative diseases including Alzheimer's disease and frontotemporal lobar degeneration-tau. Recently, tau positron emission tomography tracers such as [18F] AV-1451 and [18F] THK5351 have been developed to detect tau deposition in vivo. In the pres...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Jang YK,Lyoo CH,Park S,Oh SJ,Cho H,Oh M,Ryu YH,Choi JY,Rabinovici GD,Kim HJ,Moon SH,Jang H,Lee JS,Jagust WJ,Na DL,Kim JS,Seo SW

更新日期：2018-03-01 00:00:00

abstract：:The aim of this study was to determine the yield of attenuation correction in myocardial perfusion imaging (MPI), before and after a 1-year experience period. In 48 consecutive patients referred for MPI, both non-corrected (NC) and attenuation-corrected (AC) images were analysed by three independent readers shortly af...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Slart RH,Que TH,van Veldhuisen DJ,Poot L,Blanksma PK,Piers DA,Jager PL

更新日期：2003-11-01 00:00:00

abstract：:This study investigated the feasibility of ordered subsets expectation maximisation (OS-EM) reconstruction of 180 degrees pinhole single-photon emission tomography (SPET) acquired in body contour mode (variable distance between the detector and the axis of rotation for each projection) with or without a tilted detecto...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Seret A,Flérès D,Firket O,Defrise M

更新日期：2003-09-01 00:00:00

abstract：INTRODUCTION:Vascular prosthesis infection (VPI) is a life-threatening complication that occurs in 0.5-5% of prostheses. Low-grade infections in non-acute patients are a diagnostic challenge requiring a new method with good diagnostic accuracy. The aim of this work was to define the accuracy of (18)F-FDG PET/CT in thes...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Spacek M,Belohlavek O,Votrubova J,Sebesta P,Stadler P

更新日期：2009-05-01 00:00:00