Altered serotonin transporter availability in patients with multiple sclerosis.

abstract：:Transmission measurement is recommended in order to accurately correct for attenuation in myocardial single-photon emission tomography (SPET) studies. It is important that transmission studies are artefact-free, otherwise the attenuation-corrected SPET studies may also be affected. An assumption in transmission studie...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Evans SG,Hutton BF

更新日期：2004-05-01 00:00:00

abstract：:It has been suggested that determination of differential renal function (DRF)using technetium-99m dimercaptosuccinic acid (DMSA) may lead to overestimation of the function of an obstructed kidney in patients with excretion abnormalities owing to pelvic retention of DMSA. Recently published guidelines have recommended ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kabasakal L,Turkmen C,Ozmen O,Alan N,Onsel C,Uslu I

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:No data are yet available in the literature concerning 3-D [(123)I]-meta-iodobenzylguanidine ([(123)I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [(123)I]-MIBG kinetic analysis using a CZT ultrafast camera. METHODS:The study group comprised 16 patients consecutively sc...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Tinti E,Positano V,Giorgetti A,Marzullo P

更新日期：2014-01-01 00:00:00

abstract：:As measurement of glomerular filtration rate (GFR) is now generally the responsibility of departments of nuclear medicine, it is important for nuclear medicine physicians and scientists to understand the pharmacokinetics of the indicators and radiotracers that are used, generally known as filtration markers. The singl...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Peters AM

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:We compared the prognostic value of 99mTc-tetrofosmin single-photon emission computed tomography (SPECT) after nitrate administration and positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) in patients with ischaemic left ventricular (LV) dysfunction. METHODS:Eighty-nine patients with previous...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sorrentino AR,Acampa W,Petretta M,Mainolfi C,Salvatore M,Cuocolo A

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:High-energy gamma probes have recently become commercially available, developed for (18)F-FDG probe-guided surgery. The radiation received by the staff in the operating room might limit the use of it, but has never been determined. We therefore wanted to measure the absorbed staff doses at operations where pati...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Andersen PA,Chakera AH,Klausen TL,Binderup T,Grossjohann HS,Friis E,Palnaes Hansen C,Schmidt G,Kjaer A,Hesse B

更新日期：2008-03-01 00:00:00

abstract：PURPOSE:An image-based scatter correction (IBSC) method was developed to convert scatter-uncorrected into scatter-corrected SPECT images. The purpose of this study was to validate this method by means of phantom simulations and human studies with 99mTc-labeled tracers, based on comparison with the conventional triple e...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Shidahara M,Watabe H,Kim KM,Kato T,Kawatsu S,Kato R,Yoshimura K,Iida H,Ito K

更新日期：2005-10-01 00:00:00

abstract：INTRODUCTION:Tumor hypoxia is a centerpiece of disease progression mechanisms such as neoangiogenesis or aggressive hypoxia-resistant malignant cells selection that impacts on radiotherapy strategies. Early identification of regions at risk for recurrence and prognostic-based classification of patients is a necessity t...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Leimgruber A,Hickson K,Lee ST,Gan HK,Cher LM,Sachinidis JI,O'Keefe GJ,Scott AM

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:The aims of this study were (1) to evaluate FDG PET/CT and CT for the detection of axillary lymph node metastases in breast cancer (BC) patients and (2) to evaluate FDG PET/CT as a pre-test for the triage to sentinel lymph node biopsy (SLNB) versus axillary lymph node dissection (ALND). METHODS:The sensitivity...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Heusner TA,Kuemmel S,Hahn S,Koeninger A,Otterbach F,Hamami ME,Kimmig KR,Forsting M,Bockisch A,Antoch G,Stahl A

更新日期：2009-10-01 00:00:00

abstract：:This review summarises the evidence for the role of myocardial perfusion scintigraphy (MPS) in patients with known or suspected coronary artery disease. It is the product of a consensus conference organised by the British Cardiac Society, the British Nuclear Cardiology Society and the British Nuclear Medicine Society ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Underwood SR,Anagnostopoulos C,Cerqueira M,Ell PJ,Flint EJ,Harbinson M,Kelion AD,Al-Mohammad A,Prvulovich EM,Shaw LJ,Tweddel AC,British Cardiac Society.,British Nuclear Cardiology Society.,British Nuclear Medicine Society.,Ro

更新日期：2004-02-01 00:00:00

abstract：:Physiologically increased pancreatic uptake at the head/uncinate process is observed in more than one-third of patients after injection of one of the three (68)Ga-labelled octreotide-based peptides used for somatostatin (sst) receptor (r) imaging. There are minor differences between these (68)Ga-sstr-binding peptides ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Virgolini I,Gabriel M,Kroiss A,von Guggenberg E,Prommegger R,Warwitz B,Nilica B,Roig LG,Rodrigues M,Uprimny C

更新日期：2016-10-01 00:00:00

abstract：PURPOSE:To evaluate, in patients with chest pain, the diagnostic value of ST elevation (STE) in lead aVR during stress testing prior to (99m) Tc-sestamibi scanning correlating ischaemic territory with angiographic findings. METHODS:Consecutive patients attending for (99m) Tc-sestamibi myocardial perfusion imaging (MPI...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Neill J,Shannon HJ,Morton A,Muir AR,Harbinson M,Adgey JA

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:(18)F-8-cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine ((18)F-CPFPX) is a potent radioligand to study human cerebral A(1) adenosine receptors and their neuromodulatory and neuroprotective functions with positron emission tomography (PET). The purpose of this study was to determine the biodistribution and the r...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Herzog H,Elmenhorst D,Winz O,Bauer A

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:The presence of lymph node involvement (N) and distant metastasis (M) in patients with invasive bladder carcinoma is a major determinant of survival and, therefore, a pivotal element in the therapeutic management. The aim of this prospective study was to evaluate the use of( 18)F-fluorodeoxyglucose positron emi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Drieskens O,Oyen R,Van Poppel H,Vankan Y,Flamen P,Mortelmans L

更新日期：2005-12-01 00:00:00

abstract：PURPOSE:The aim of the study was to assess the role of CA 15.3, CT and positron emission tomography (PET)/CT in patients with breast cancer and suspected disease relapse after primary treatment. METHODS:We studied 111 consecutive patients (mean age 61 ± 12 years) with previous breast cancer, already treated and with c...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Evangelista L,Baretta Z,Vinante L,Cervino AR,Gregianin M,Ghiotto C,Saladini G,Sotti G

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:While methods for imaging tumor hypoxia with positron emission tomography (PET) have been developed, optimal methods for interpreting and utilizing these datasets in the clinic remain unclear. In this study, we analyzed hypoxia PET images of head and neck cancer patients and compared imaging metrics with human ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Graves EE,Hicks RJ,Binns D,Bressel M,Le QT,Peters L,Young RJ,Rischin D

更新日期：2016-04-01 00:00:00

abstract：:We present a system of image co-registration and its validation in phantom and volunteer studies. The system co-registered images via six novel non-invasive and non-radioactive external markers. The fiducial markers were attached with sponge bases on the skin surface of the phantom and the volunteers in a non-collinea...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wu TH,Wang JK,Lee JJ,Liu RS,Guo WY

更新日期：2003-06-01 00:00:00

abstract：:Radiomics in nuclear medicine is rapidly expanding. Reproducibility of radiomics studies in multicentre settings is an important criterion for clinical translation. We therefore performed a meta-analysis to investigate reproducibility of radiomics biomarkers in PET imaging and to obtain quantitative information regard...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zwanenburg A

更新日期：2019-12-01 00:00:00

abstract：:The human cardiac nervous system consists of a sympathetic and a parasympathetic branch with (-)-norepinephrine and acetylcholine as the respective endogenous neurotransmitters. Dysfunction of the cardiac nervous system is implicated in various types of cardiac disease, such as heart failure, myocardial infarction and...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Langer O,Halldin C

更新日期：2002-03-01 00:00:00

abstract：PURPOSE:Investigate whether 18F-FDG PET-CT has the potential to predict the major pathologic response (MPR) to neoadjuvant sintilimab in resectable NSCLC patients, and the potential of sifting patients who probably benefit from immunotherapy. METHODS:Treatment-naive patients with resectable NSCLC (stage IA-IIIB) recei...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Tao X,Li N,Wu N,He J,Ying J,Gao S,Wang S,Wang J,Wang Z,Ling Y,Tang W,Zhang Z

更新日期：2020-05-01 00:00:00

abstract：:The biodistribution of radioactivity after the administration of a new tracer for alpha4beta2 nicotinic acetylcholine receptors (nAChRs), [123I]5-iodo-3-[2(S)-2-azetidinylmethoxy]pyridine (5-I-A-85380), was studied in ten healthy human subjects. Following administration of 98+/-6 MBq [123I]5-I-A-85380, serial whole-bo...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Fujita M,Seibyl JP,Vaupel DB,Tamagnan G,Early M,Zoghbi SS,Baldwin RM,Horti AG,KoreN AO,Mukhin AG,Khan S,Bozkurt A,Kimes AS,London ED,Innis RB

更新日期：2002-02-01 00:00:00

abstract：PURPOSE:The dopamine transporter (DAT) is a plasma membrane protein of central interest in the pathophysiology of neuropsychiatric disorders and is known to be a target for psychostimulant drugs. [(11)C]PE2I is a new radioligand which binds selectively and with moderate affinity to central DAT, as has been demonstrated...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Jucaite A,Odano I,Olsson H,Pauli S,Halldin C,Farde L

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:PET is a powerful tool for assessing targeted therapy. Since (18)F-FDG shows a potential prognostic value in medullary thyroid carcinoma (MTC), this study evaluated (18)F-FDG PET alone and combined with morphological and biomarker evaluations as a surrogate marker of overall survival (OS) in patients with progr...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Salaun PY,Campion L,Ansquer C,Frampas E,Mathieu C,Robin P,Bournaud C,Vuillez JP,Taieb D,Rousseau C,Drui D,Mirallié E,Borson-Chazot F,Goldenberg DM,Chatal JF,Barbet J,Kraeber-Bodéré F

更新日期：2014-08-01 00:00:00

abstract：:The trade-off between resolution and count sensitivity dominates the performance of standard gamma cameras and dictates the need for relatively high doses of radioactivity of the used radiopharmaceuticals in order to limit image acquisition duration. The introduction of cadmium-zinc-telluride (CZT)-based cameras may o...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Agostini D,Marie PY,Ben-Haim S,Rouzet F,Songy B,Giordano A,Gimelli A,Hyafil F,Sciagrà R,Bucerius J,Verberne HJ,Slart RH,Lindner O,Übleis C,Hacker M,Cardiovascular Committee of the European Association of Nuclear Medicine (E

更新日期：2016-12-01 00:00:00

abstract：:In locally advanced head and neck squamous cell carcinoma (HNSCC), the role of imaging becomes more and more critical in the management process. In this framework, molecular imaging techniques such as PET allow noninvasive assessment of a range of tumour biomarkers such as metabolism, hypoxia and proliferation, which ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Differding S,Hanin FX,Grégoire V

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:Focal congenital hyperinsulinism (CHI) is curable by surgery, which is why identification of the focal lesion is crucial. We aimed to determine the use of 18F-fluoro-dihydroxyphenylalanine (18F-DOPA) PET/CT vs. 68Ga-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic-acid-1-Nal3-octreotide (68Ga-DOTANOC) PET/CT...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Christiansen CD,Petersen H,Nielsen AL,Detlefsen S,Brusgaard K,Rasmussen L,Melikyan M,Ekström K,Globa E,Rasmussen AH,Hovendal C,Christesen HT

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:The future significance of peptide radiopharmaceuticals in diagnostic imaging with PET will be dependent on methodological aspects, as well as other requirements such as availability of the radionuclide and cost-effectiveness of its production. The aim of this study was to evaluate whether recent improvements i...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Henriksen G,Schottelius M,Poethko T,Hauser A,Wolf I,Schwaiger M,Wester HJ

更新日期：2004-12-01 00:00:00

abstract：:Cardiac sarcoidosis (CS) is a rare and potentially life-threatening disease that causes conduction disturbance, systolic dysfunction, and most notably sudden cardiac death. Accurate diagnosis of CS is thus mandatory; however, a reliable approach that enables diagnosis of CS with high sensitivity and specificity has ye...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ohira H,Tsujino I,Yoshinaga K

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:It has been shown that some primary human tumours and their metastases, including prostate and breast tumours, overexpress gastrin-releasing peptide (GRP) receptors. Bombesin (BN) is a neuropeptide with a high affinity for these GRP receptors. We demonstrated successful scintigraphic visualisation of BN recepto...

journal_title：European journal of nuclear medicine and molecular imaging

authors： de Visser M,Bernard HF,Erion JL,Schmidt MA,Srinivasan A,Waser B,Reubi JC,Krenning EP,de Jong M

更新日期：2007-08-01 00:00:00

abstract：UNLABELLED:The aim of this study was to evaluate the feasibility of using [(18)F] 3'-deoxy-3'-fluorothymidine (FLT) positron emission tomography (PET) for the diagnosis and grading of brain tumors. METHODS:The patient population comprised 26 patients (15 males, 11 females) with brain tumors (n=18) or nontumorous lesio...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Choi SJ,Kim JS,Kim JH,Oh SJ,Lee JG,Kim CJ,Ra YS,Yeo JS,Ryu JS,Moon DH

更新日期：2005-06-01 00:00:00