Neuroprotective effects of Aceglutamide on motor function in a rat model of cerebral ischemia and reperfusion.

abstract：:Purpose: Damage of primary visual cortex in adult humans, monkeys and cats severely disrupts vision by disconnecting much of the cogni-tive processing machinery of extrastriate cortex from its source of visual signals in the retina. Equivalent lesions sustained early in life result in partial sparing of visual process...

journal_title：Restorative neurology and neuroscience

authors： Payne BR,Lomber SG

更新日期：2000-01-01 00:00:00

abstract：:It is widely accepted that the suprachiasmatic nuclei (SCN) of the hypothalamus serve as biological pacemakers, organizing daily activities. However some circadian rhythms are controlled by extra-SCN structures. Transplantation of fetal donor SCN in SCN-lesioned rodents induces recovery of rhythmic locomotor and drink...

journal_title：Restorative neurology and neuroscience

authors： Le Sauter J,Silver R

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:The aim of the present study was to explore the use of two-photon microscopy for investigating the therapeutic time window of methylprednisolone (MP) treatment after spinal cord injury (SCI). METHODS:Twenty-four YFP H-line mice were subjected to hemisection SCI and then divided into four groups. Group 1 receiv...

journal_title：Restorative neurology and neuroscience

authors： Zhang Y,Zhang L,Ji X,Pang M,Ju F,Zhang J,Li W,Zhang S,He Z,Gan WB,Tang P

更新日期：2015-01-01 00:00:00

abstract：:Following brain injury there is an excessive release of glutamate, a reduction in levels of cellular Mg+ +, and the generation of oxygen free radicals. These processes may contribute to the severity of the behavioral impairments seen following brain injury by leading to secondary neuronal degeneration. The present exp...

journal_title：Restorative neurology and neuroscience

authors： Hoane MR,Raad C,Barth TM

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Traumatic brain injury can result in lasting cognitive dysfunction due to degeneration of mature hippocampal neurons as well as the loss of immature neurons within the dentate gyrus. While endogenous neurogenesis affords a partial recovery of the immature neuron population, hippocampal neurogenesis may be en...

journal_title：Restorative neurology and neuroscience

authors： Sama DM,Carlson SW,Joseph B,Saenger S,Metzger F,Saatman KE

更新日期：2018-01-01 00:00:00

abstract：:Purpose: Caspase-3 is known as a crucial effector for apoptotic cell death. Apoptosis has recently been recognized as an important cell death mechanism after spinal cord injury (SCI). This study attempts to define the effect of methylprednisolone (MP) on the activation of caspase-3 in the lesioned area following SCI. ...

journal_title：Restorative neurology and neuroscience

authors： Li X,Oudega M,Dancausse HA,Levi AD

更新日期：2000-01-01 00:00:00

abstract：:Corticomotor excitability is reduced during rhythmic passive movement compared to rest, but it is not known whether the mechanism is purely segmental or includes a supraspinal pathway. To determine how interruption of sensory projections at a supraspinal level affects corticomotor excitability during passive movement,...

journal_title：Restorative neurology and neuroscience

authors： Edwards DJ,Mastaglia FL,Byrnes ML,Fregni F,Pascual-Leone A,Thickbroom GW

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:Understanding the neural mechanisms of stroke recovery is of paramount importance for neurorehabilitation. METHODS:For this purpose, we analyzed several TMS and EEG variables and their association with motor recovery. Thirty-five subjects with chronic stroke were recruited. The neurophysiological examination i...

journal_title：Restorative neurology and neuroscience

authors： Simis M,Doruk D,Imamura M,Anghinah R,Morales-Quezada L,Fregni F,Battistella LR

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Oxidative stress is an important factor in the pathophysiologic changes after traumatic brain injury (TBI). Connexin43 (Cx43) was reported to contribute to cerebral damage. However, the impacts of Cx40 have not been investigated in detail. OBJECTIVE:In the present study, we hypothesized that Cx40 was involv...

journal_title：Restorative neurology and neuroscience

authors： Chen W,Guo Y,Yang W,Zheng P,Zeng J,Tong W

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The patients with chronic Disorders of Consciousness (DoC) mostly present with extremely challenging differential diagnosis. The advanced analysis of electroencephalographic (EEG) signals induced by brain stimulation paradigms may provide an appropriate approach to differentiate patients with DoC, besides th...

journal_title：Restorative neurology and neuroscience

authors： Naro A,Leo A,Bruno R,Cannavò A,Buda A,Manuli A,Bramanti A,Bramanti P,Calabrò RS

更新日期：2017-01-01 00:00:00

abstract：:Melatonin (MLT) is a methoxyindole secreted principally by the pineal gland. It is synthesized at night under normal environmental conditions. The endogenous rhythm of secretion is generated by the suprachiasmatic nuclei and entrained by the light/dark cycle. Light is able to both suppress or synchronize melatonin pro...

journal_title：Restorative neurology and neuroscience

authors： Claustrat B,Brun J,Geoffriau M,Chazot G

更新日期：1998-06-01 00:00:00

abstract：:Administration of gangliosides accelerates recovery of function after entorhinal cortex lesions on open field activity and learned spatial alternation tasks. In the present study, we examined whether GM1 ganglioside might enhance recovery from bilateral entorhinal cortex lesions on a differential reinforcement of low-...

journal_title：Restorative neurology and neuroscience

authors： Ramirez JJ,MacDonald K,Mañibo J,Payne J,Tuite C

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:The illusory ownership of a fake hand as part the body follows synchronous tactile stimulation over a visible rubber hand and a covered hand. Whether brain plasticity mechanisms after sensory and motor disconnection modulates this illusion remain unexplored. METHODS:We tested a tetraplegic man after synchronou...

journal_title：Restorative neurology and neuroscience

authors： Tidoni E,Grisoni L,Liuzza MT,Aglioti SM

更新日期：2014-01-01 00:00:00

abstract：:Although neurotransmitter-based hypotheses still prevail current thinking about the mechanism of action of psychotropic drugs, recent insight into the pathophysiology of psychiatric disorders has unveiled a range of new therapeutic actions of the drugs used to treat those disorders. Especially antidepressants seem to ...

journal_title：Restorative neurology and neuroscience

authors： Paulzen M,Veselinovic T,Gründer G

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To assess whether insights from postural control without additional visual feedback (VFB) could be gained to explain the possible VFB effects (or non-effects) on upright stance performance. METHODS:The center-of-pressure (CP) displacements of 39 patients with a recent hemispheric stroke (93 days ± 56; mean ± s...

journal_title：Restorative neurology and neuroscience

authors： Rougier P,Boudrahem S

更新日期：2010-01-01 00:00:00

abstract：:The aim of this study was to gauge the possible sprouting of primary afferent fibers following dorsal rhizotomies using Fos-like immunoreactivity (Fos-LI) in order to label neurons activated by formalin injection into the rat forepaw. To assess the functional consequences of possible sprouting of fine diameter primary...

journal_title：Restorative neurology and neuroscience

authors： Abbadie C,Lombard MC,Morain F,Besson JM

更新日期：1994-01-01 00:00:00

abstract：:Many of the present limitations of peripheral nerve repair might be overcome by performing nerve repairs at the axon level. One approach to nerve repair at this level would be to implant a neuroprosthesis in the form of a microelectronic switchboard which could route the connections of regenerated axons to their corre...

journal_title：Restorative neurology and neuroscience

authors： Rosen JM,Grosser M,Hentz VR

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:Despite advances towards potential clinically viable therapies there has been only limited success in improving functional recovery following traumatic brain injury (TBI). In rats, exposure to an enriched environment (EE) improves learning and fosters motor skill development. Induced pluripotent stem cells (iPS...

journal_title：Restorative neurology and neuroscience

authors： Dunkerson J,Moritz KE,Young J,Pionk T,Fink K,Rossignol J,Dunbar G,Smith JS

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Multiple Sclerosis is a heterogeneous disorders involving in early stage gait and balance. Together with immunomodulating therapies, rehabilitation had a crucial role in improving motor tasks and quality of life. Between the emerging techniques, Focal Vibrations (FV) could play a role, but they have been use...

journal_title：Restorative neurology and neuroscience

authors： Spina E,Carotenuto A,Aceto MG,Cerillo I,Silvestre F,Arace F,Paone P,Orefice G,Iodice R

更新日期：2016-09-21 00:00:00

abstract：:In rat sciatic nerves, IGF-I or bFGF was applied distal to a crush to evaluate their effects upon the restoration of the neuromuscular function. In comparison with the recovery following a simple crush, treatment with growth factors resulted in (i) enhanced elongation of regenerating axons ( + 24%) up to day 3 post le...

journal_title：Restorative neurology and neuroscience

authors： Vergara J,Medina L,Maulén J,Inestrosa NC,Alvarez J

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Focal dystonia in musicians (MD) is a task-specific movement disorder with a loss of voluntary motor control during instrumental playing. Defective inhibition on different levels of the central nervous system is involved in the pathophysiology. Sensorimotor retraining is a therapeutic approach to MD and aims...

journal_title：Restorative neurology and neuroscience

authors： Buttkus F,Baur V,Jabusch HC,de la Cruz Gomez-Pellin M,Paulus W,Nitsche MA,Altenmüller E

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:Accurate coil placement over a target area is critical during transcranial magnetic stimulation (TMS), as small deviations can alter testing outcomes. Accordingly, frameless stereotaxic systems (FSS) are recommended for reliable coil placement during TMS applications. However, FSS is not practical due to the co...

journal_title：Restorative neurology and neuroscience

authors： Washabaugh EP,Krishnan C

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Several studies have shown that transcranial direct current stimulation (tDCS) is a useful tool to enhance language recovery in aphasia. It has also been suggested that modulation of the neurotrophin brain-derived neurotrophic factor (BDNF) might be part of the mechanisms involved in tDCS effects on synaptic co...

journal_title：Restorative neurology and neuroscience

authors： Marangolo P,Fiori V,Gelfo F,Shofany J,Razzano C,Caltagirone C,Angelucci F

更新日期：2014-01-01 00:00:00

abstract：:Embryonic stem (ES) cells have the ability to differentiate into a variety of cell lineages. We are examining ES cell differentiation in vitro by using cDNA microarrays to generate a molecular phenotype for each cell type. El4 ES cells induced by retinoic acid after forming embryoid bodies differentiate almost exclusi...

journal_title：Restorative neurology and neuroscience

authors： Loring JF,Porter JG,Seilhammer J,Kaser MR,Wesselschmidt R

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:Current models of intracerebral hematoma are difficult to use for neurotransplantation studies because of high mortality and important variations of morphology, size and location of blood deposits. We propose a modification of the autologous blood infusion technique in rats to reduce these limitations. METHODS...

journal_title：Restorative neurology and neuroscience

authors： Barth A,Guzman R,Andres RH,Mordasini P,Barth L,Widmer HR

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:Bacopa monnieri (L.) WETTST. is extensively used in traditional Indian medicine as a nerve tonic. The neuropharmacological properties of bacopaside I, an important component from B. monnieri, have not been studied so far. The present study investigated the effects and possible mechanisms of bacopaside I in a ra...

journal_title：Restorative neurology and neuroscience

authors： Liu X,Yue R,Zhang J,Shan L,Wang R,Zhang W

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:Immunomodulatory agents are often combined in organ transplantation to minimize toxicity and enhance therapeutic effect. We hypothesized that combining low-dose FK506 with anti-CD40 Ligand (anti-CD40L mAb) would enhance regeneration through peripheral nerve allografts while preserving immune unresponsiveness. ...

journal_title：Restorative neurology and neuroscience

authors： Brenner MJ,Mackinnon SE,Rickman SR,Jaramillo A,Tung TH,Hunter DA,Mohanakumar T

更新日期：2005-01-01 00:00:00

abstract：:The application of brain stimulation techniques for modulation of cortical excitability changes underlying spatial neglect following right-brain-damage has been the first application of brain stimulation in the rehabilitation setting. Several factors concur in making neglect a prototype of cognitive disorders that can...

journal_title：Restorative neurology and neuroscience

authors： Oliveri M

更新日期：2011-01-01 00:00:00

abstract：:Various basic qualitative and quantitative methods for the evaluation of sensorimotor functions after Traumatic Brain Injury (TBI) are introduced and discussed. Methodological aspects are illustrated by a single case follow-up study of a child after severe TBI (age 11; 7–12;1 yrs; 6, 8 and 12 month post TBI) in compar...

journal_title：Restorative neurology and neuroscience

authors： Jöhnk K,Kuhtz-Buschbeck JP,Stolze H,Serocki G,Kalwa S,Ritz A,Benz B,Illert M

更新日期：1999-01-01 00:00:00

abstract：:Animals with unilateral neurotoxic lesions in the striatum exhibit a stereotypical biased rotational behavior in response to dopamine agonists. We recently argued that the rotational test may be subject to sensitization effects of the drug. Accordingly, we proposed the drug-free elevated body swing test (EBST) as an a...

journal_title：Restorative neurology and neuroscience

authors： Borlongan CV,Cahill DW,Sanberg PR

更新日期：1995-01-01 00:00:00