Prognosis and Treatment of Visual Field Defects.

abstract：:Emery-Dreifuss muscular dystrophy (EDMD) is the third most common X-linked muscular dystrophy. This disorder is characterized by childhood onset of early contractures, humeroperoneal muscle atrophy, and cardiac conduction abnormalities. Weakness is slowly progressive, but there is a broad spectrum of clinical severity...

journal_title：Seminars in neurology

authors： Zacharias AS,Wagener ME,Warren ST,Hopkins LC

更新日期：1999-01-01 00:00:00

abstract：:Charcot-Marie-Tooth (CMT) disease is caused by mutations in several genes expressed in myelinating Schwann cells and the axons they ensheathe. Typical patients present with distally accentuated motor weakness, muscle wasting, and sensory loss leading to significant and progressive clinical morbidity and impaired quali...

journal_title：Seminars in neurology

authors： Jani-Acsadi A,Krajewski K,Shy ME

更新日期：2008-04-01 00:00:00

abstract：:Gastrointestinal motor dysfunctions result when extrinsic autonomic nerves are diseased and are unable to modulate the motor functions of the digestive tract, which depend on the enteric nervous system and the automaticity of the smooth muscles. Gut motor dysfunction may result from disorders at all anatomic levels of...

journal_title：Seminars in neurology

authors： Camilleri M,Bharucha AE

更新日期：1996-09-01 00:00:00

abstract：:Evaluation of patients with cranial neuropathies requires an understanding of brainstem anatomy and nerve pathways. Advances in neuroimaging, particularly high spatial resolution magnetic resonance imaging (MRI), have enabled visualization of these tiny structures and their related pathology. This review provides an a...

journal_title：Seminars in neurology

authors： Jha RM,Klein JP

更新日期：2012-09-01 00:00:00

abstract：:Cancer therapy can cause several neurotoxic syndromes that are associated with distinct findings on cranial imaging. With the use of more aggressive and combined treatment modalities in oncology and prolonged overall patient survival, neurotoxicity has been reported with increasing frequency in patients with brain can...

journal_title：Seminars in neurology

authors： Arrillaga-Romany IC,Dietrich J

更新日期：2012-09-01 00:00:00

abstract：:Physician-hastened-death remains a controversial topic for patients and those who care for them. It is a particularly relevant topic for neurologists who currently, or will in the future, reside in jurisdictions where physician-hastened-death is legal. In this article, I attempt to provide a comprehensive and contempo...

journal_title：Seminars in neurology

authors： Russell JA

更新日期：2018-10-01 00:00:00

abstract：:Immunotherapy of multiple sclerosis (MS) will continue to benefit from an increasing understanding of this disease. This knowledge results in newly defined targets for novel therapies. In this article the development of future immunotherapies will be discussed by classifying the approaches into three main types: (1) a...

journal_title：Seminars in neurology

authors： Blevins G,Martin R

更新日期：2003-06-01 00:00:00

abstract：:Pregnancy and the postpartum period confer an increased risk of stroke. The risk appears to be increased for all strokes during the puerperium and for hemorrhagic strokes during pregnancy. During pregnancy, physiologic systems are under increased stress to accommodate the growing fetus, which results in substantial he...

journal_title：Seminars in neurology

authors： Sells CM,Feske SK

更新日期：2017-12-01 00:00:00

abstract：:Blepharospasm is a focal dystonia characterized by involuntary, repetitive eye closure. Orofacial and oromandibular dystonia describe involuntary dystonic movements of orofacial and oromandibular musculature. Hemifacial spasm is characterized by repetitive synchronous contraction of facial nerve innervated muscles on ...

journal_title：Seminars in neurology

authors： Karp BI,Alter K

更新日期：2016-02-01 00:00:00

abstract：:Neuropathic pain management is challenging, and typically requires a multifaceted approach. There are several treatment options, both pharmacologic and nonpharmacologic. Of the available pharmacologic agents, those with the strongest supporting evidence include tricyclic antidepressants, serotonin-norepinephrine reupt...

journal_title：Seminars in neurology

authors： Macone A,Otis JAD

更新日期：2018-12-01 00:00:00

abstract：:Psychogenic (nonepileptic) seizures are among the most common and serious of all psychogenic neurological disorders. They account for approximately 20% of all intractable seizure disorders referred to comprehensive epilepsy centers and present with a reported annual incidence of approximately 4% that of true epilepsy....

journal_title：Seminars in neurology

authors： Krumholz A,Hopp J

更新日期：2006-07-01 00:00:00

abstract：:Headaches are a common complaint for most women during their lifetime, including gestation and puerperium. Tension-type headaches and migraine flare-ups are the most common headache complications after delivery, but the differential diagnosis of postpartum headache is broad. The clinician must distinguish common heada...

journal_title：Seminars in neurology

authors： Cardona L,Klein AM

更新日期：2011-09-01 00:00:00

abstract：:Both general neurologists and neurologists with a broad spectrum of subspecialty interests are often asked to evaluate patients with disorders of the spinal cord. Over the past decade, there have been significant advances in our understanding of a wide spectrum of immune-mediated, infectious, metabolic, hereditary, pa...

journal_title：Seminars in neurology

authors： Kumar N

更新日期：2010-02-01 00:00:00

abstract：:The diagnosis of inherited neuropathies can be challenging in several ways. First, a hereditary neuropathy must be suspected. Although some family histories are clear with multiple members affected, other families require directed inquiry. Second, even when a hereditary neuropathy is clear, it can be difficult to make...

journal_title：Seminars in neurology

authors： Lawson V,Gharibshahi S

更新日期：2010-09-01 00:00:00

abstract：:Diet may influence stroke risk via several mechanisms, but the optimal dietary habits for stroke prevention are not well established. We reviewed English-language MEDLINE publications from January 1979 through November 2004 for experimental, observational, and clinical studies of dietary factors (minerals, fats, chole...

journal_title：Seminars in neurology

authors： Ding EL,Mozaffarian D

更新日期：2006-02-01 00:00:00

abstract：:The clinical evaluation of peripheral neuropathies can be challenging. This article presents an approach based on a structured assessment that asks a series of yes or no questions during the history and examination that leads to localization and characterization of the neuropathy. The final assessment includes further...

journal_title：Seminars in neurology

authors： Bromberg MB

更新日期：2005-06-01 00:00:00

abstract：:In addition to sharing several clinical, pathologic, and molecular characteristics, many neurodegenerative disorders show extensive familial histories suggesting a substantial contribution of genetic factors to disease causation and progression. In this review, the authors provide overviews of the status of current ge...

journal_title：Seminars in neurology

authors： Lill CM,Bertram L

更新日期：2011-11-01 00:00:00

abstract：:Calcineurin inhibitor encephalopathy (CIE) is a rare condition occurring in patients who are undergoing treatment with drugs from the calcineurin inhibitor (CI) family of immunosuppressants, either cyclosporine (CsA) or tacrolimus (TAC, FK506). Generally acute in onset, the symptoms are commonly reversible if properly...

journal_title：Seminars in neurology

authors： Mammoser A

更新日期：2012-11-01 00:00:00

abstract：:Besides sleep apnea, the main disorders of excessive daytime sleepiness include narcolepsy and hypersomnia. Narcolepsy is characterized by periods of irresistible sleepiness and sleep attacks of brief duration and, most often, by one or more of the auxiliary symptoms: cataplexy, sleep paralysis, and hypnogogic halluci...

journal_title：Seminars in neurology

authors： Manfredi RL,Brennan RW,Cadieux RJ

更新日期：1987-09-01 00:00:00

abstract：:The human genome has become a roadmap for elucidation of the pathophysiology of disease. It is likely that mutations in more than 1000 of the approximately 30,000 human genes will lead to autonomic abnormalities, either directly or indirectly. This review highlights some of these, which exert major effects on catechol...

journal_title：Seminars in neurology

authors： Taneja I,Robertson D

更新日期：2003-12-01 00:00:00

abstract：:Parkinsonism is a clinical syndrome, which is characterized by bradykinesia, rigidity, rest tremor, and postural instability. Idiopathic Parkinson disease (PD) is the most common cause of this syndrome, though there are several other important etiologies that must be considered. These include the atypical Parkinsonian...

journal_title：Seminars in neurology

authors： Keener AM,Bordelon YM

更新日期：2016-08-01 00:00:00

abstract：:The field of neurocritical care has evolved tremendously in recent years, a development explained vastly by the advent of neurophysiological monitoring. From basic intracranial pressure measurements to brain tissue oxygenation, microdialysis, cerebral blood flow (CBF), and surface and intracortical electroencephalogra...

journal_title：Seminars in neurology

authors： Francoeur CL,Pain M,Mayer SA

更新日期：2016-12-01 00:00:00

abstract：:Neuroimaging is commonly utilized in the evaluation of post-cardiac arrest patients, providing a unique ability to visualize and quantify structural brain injury that can complement clinical and electrophysiologic data. Despite its lack of validation, we would advocate that neuroimaging is a valuable prognostication t...

journal_title：Seminars in neurology

authors： Greer DM,Wu O

更新日期：2017-02-01 00:00:00

abstract：:Treatment of dementias represents an important but relatively neglected part of neurological care of the elderly population. Individual therapeutic interventions may make only small changes to the quality of life of individuals afflicted with dementia, but when used in combination these interventions synergize and can...

journal_title：Seminars in neurology

authors： Tisher A,Salardini A

更新日期：2019-04-01 00:00:00

abstract：:The management of epilepsy in women encompasses a complex interplay between seizures, sex steroid hormones, and antiepileptic drugs (AEDs). These interactions impact every aspect of the sexual and reproductive health of women with epilepsy throughout their lifetimes. Neurologists comfortable treating seizures may feel...

journal_title：Seminars in neurology

authors： Noe KH

更新日期：2007-09-01 00:00:00

abstract：:Improved disease control is critical for enhancing the lives of those living with multiple sclerosis. With specific immunologic targets, monoclonal antibody (mAb) treatments are highly effective options for relapsing forms of multiple sclerosis. The mechanism, efficacy, and current safety profiles are detailed for the...

journal_title：Seminars in neurology

authors： Singer BA

更新日期：2016-04-01 00:00:00

abstract：:Pain is common but often underrecognized after stroke. Poststroke pain (PSP) hinders recovery, impairs quality of life, and is associated with the psychological state of patients with stroke. The most common subtypes of PSP include central PSP, complex regional pain syndrome, shoulder pain, spasticity-related pain, an...

journal_title：Seminars in neurology

authors： Yang S,Chang MC

更新日期：2021-01-14 00:00:00

abstract：:Lightning and electrical injuries have widespread manifestations involving almost all organ systems of the body, including the central nervous system (CNS) and the eye. This article considers the neuro-ophthalmologic effects of lightning and electrical injury. ...

journal_title：Seminars in neurology

authors： Grover S,Goodwin J

更新日期：1995-12-01 00:00:00

abstract：:Delusions may be the most prominent manifestations of brain dysfunction, and a host of medical and neurologic conditions can present with or produce delusions. Recognition of the underlying disorder frequently aids in successful treatment. Comparison of organic delusional syndromes with schizophrenia suggests that lim...

journal_title：Seminars in neurology

authors： Gorman DG,Cummings JL

更新日期：1990-09-01 00:00:00

abstract：:Reported PET findings in subcortical and corticobasal degenerations, and in dystonia, are summarized in Table 3. It can be seen that, although PET is not a diagnostic technique, clinical examination combined with PET findings can help to distinguish between the various akinetic-rigid syndromes, with the proviso that p...

journal_title：Seminars in neurology

authors： Brooks DJ

更新日期：1989-12-01 00:00:00