Abstract：
:Meningiomas are the most common primary extra-axial tumours of the central nervous system, however their metastatic spread beyond central nervous system is rare. Here we present the case of a 54-year-old male with anaplastic meningioma who, 1.5 years after initial diagnosis, developed a tumorous expansion in his left adrenal gland, showing octreotide uptake on scintigraphy. Clinical diagnosis of pheochromocytoma was made and left adrenalectomy performed. The tumour weighed 480 grams and measured up to 140 mm in diameter. On histologic examination, morphology consistent with the diagnosis of anaplastic meningioma was present, resembling the original central nervous system tumour. The tumour expressed strongly SSTR2A and focally epithelial membrane antigen, p63 and pancytokeratin (AE1/3). An extensive panel of neuronal and additional epithelial markers (SOX10, synaptophysin, chromogranin, inhibin, calretinin, BER-EP4, MOC31) was negative. The review of the literature on meningioma metastasising outside the central nervous system and on its differential diagnosis is provided.
journal_name
Folia Neuropatholjournal_title
Folia neuropathologicaauthors
Soukup J,Kasparova P,Vajda M,Ryska Adoi
10.5114/fn.2019.91195subject
Has Abstractpub_date
2019-01-01 00:00:00pages
366-372issue
4eissn
1641-4640issn
1509-572Xpii
39386journal_volume
57pub_type
杂志文章abstract：:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutations in the NOTCH3 gene. Pathophysiologically, there seems to be multimerization of the extracellular domain of the protein with a possible gain of function on vascular smooth muscular cells. However,...
journal_title：Folia neuropathologica
pub_type： 信件
doi：10.5114/fn.2015.52414
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abstract：:Electron microscopic immunocytochemical evaluation of localization and distribution of endothelins 1, 2 and 3 in the CA1 hippocampal sector in rats submitted to 10 min global cerebral ischemia was performed. The studies were done in different postischemic periods (10 min, 3, 6, 12 and 24 h) with postembedding immuno-g...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Unmethylated CpG DNA, as a stimulatory molecule, has potent pro-inflammatory effects in the central nervous system (CNS). Dexmedetomidine (DEX) has been confirmed to exert anti-inflammatory effects in CNS. Our study was aimed to explore the effects of DEX on tumor necrosis factor-α (TNF-α) expression in unmethylated C...
journal_title：Folia neuropathologica
pub_type： 杂志文章
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abstract：:The Warburg micro syndrome (WARBM) is a genetically heterogeneous syndrome linked to at least 4 loci. At the clinical level, WARBM is characterized by microcephaly, microphthalmia, microcornea, congenital cataracts, corpus callosum hypoplasia, severe mental retardation, and hypogonadism. In some families additional cl...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：10.5114/fn.2016.62537
更新日期：2016-01-01 00:00:00
abstract：:Introduction: Mixed dementia (MixD) refers to a combination of definite Alzheimer's disease (AD) and vascular encephalopathy. The existence of a "pure" type of vascular dementia (VaD) is controversial. There is a need to find magnetic resonance imaging (MRI) characteristics allowing the distinction between V...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：10.5114/fn.2017.66711
更新日期：2017-01-01 00:00:00
abstract：:The clinical and histological picture and immunocytochemical expression of some cytokines on infiltrates in the central nervous system of Lewis rats were studied in adult rats in the course of short-term therapy of acute experimental allergic encephalomyelitis with interferon beta 1a (IFN beta 1a). There was establish...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Cerebellar cortical biopsies of the peritumoural region of seven patients with cerebellar haemangioma, mesencephalic meningioma, cerebellopontine astrocytoma, cerebellopontine meningioma, and medulloblastoma of cerebellar vermis were examined by means of conventional transmission electron microscopy. Granule cells sho...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：10.5114/fn.2016.60057
更新日期：2016-01-01 00:00:00
abstract：:A case of 56-year-old male with sarcomatosis of leptomeninges as well as of the brain and spinal cord coexisting with Recklinghausen's neurofibromatosis is presented. Neurological and neurophysiological symptoms of the disease resembled those of amyotrophic lateral sclerosis (ALS). Patient died 7 months after onset of...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:We describe here a variety of autophagous forms encountered in the terminal stages of two models of scrapie in hamsters. We also show that the number of autophagic vacuoles increased through the incubation period in the 263K strain scrapie model. In addition, we demonstrated for the first time the presence of aggresom...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:The gerbils brains after 3- and 4-minute-long ischemia caused by bilateral common carotid artery occlusion and 14 days survival were investigated using lectin techniques. Chosen lectins, represented by synthetic plant glycoproteids, which are specifically bound to particular sugar residues (receptors) located on the c...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:The inflammatory process is a nonspecific complex, stereotype, coordinated response of tissues to injury. This process involves vascular permeability, active migration of blood cells, and passage of plasma constituents into the injurious tissue. The molecules that mediate the initial events of inflammation are the adh...
journal_title：Folia neuropathologica
pub_type： 杂志文章,评审
doi：
更新日期：1998-01-01 00:00:00
abstract：:Hyponatremia is a common disorder of water-electrolyte balance characterized by the decrease of plasma sodium ions concentration below 135 mM. Although water-electrolyte balance is regulated by a kidney, symptoms of hyponatremia are related to the disturbances of intracranial homeostasis and are attributed to brain sw...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：10.5114/fn.2013.37707
更新日期：2013-01-01 00:00:00
abstract：:Chemokines play an important role in pathogenesis of multiple sclerosis (MS), mediating migration of leukocytes into the central nervous system. CCL2 (MCP-1) chemokine is expressed in astrocytes in MS lesions. The aim of the study was to evaluate the effect of a two-year treatment with IFN-beta 1a on serum CCL2 level ...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:The qualitative analysis of changes in major nuclei (n. paranigralis left and right, n. interfascicularis) of the mesocorticolimbic system (ventral tegmental area-VTA) was carried out on 25 cases with Parkinson's disease (PD). The cellular depletion with insignificant gliosis without the presence of macrophages was fo...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:We demonstrate an unusually intensive accumulation of prion protein (PrP) on neuronal membranes in hamsters infected with the Echigo-1 panencephalopathic strain of Creutzfeldt-Jakob disease. This stands in strong contrast with the poor vacuolation in this model. Several distinct patterns of PrP(TSE) deposit were obser...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:Neuronal and axonal degenerative changes in motor vagal neurons (DMNV) and sensory vagal neurons (nTS) in the medulla oblongata in newborns were studied. Material was taken from the autopsies of newborns, live and dead newborns, in different gestational weeks (aborted, immature, premature and mature). 46 cases were st...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:A case of the 18-year-old boy suffering from epilepsy since 8 years and suspected of microangioma is presented. The craniotomy revealed left parietal parasagittal superficially located neoplasm and arteriovenous malformation beneath. Unexpected fibrillary astrocytoma associated with vascular tumor was the diagnostic p...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:The aim of the study was to analyse in TEM the evolution of changes in structural elements of synaptic junctions of the cerebellar cortex in rats in valproate encephalopathy induced by chronic 12-month administration of sodium valproate - VPA (once daily intragastrically, in a dose of 200 mg/kg b.w.) and after withdra...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:Tumours of astroglial origin, both malignant glioblastoma (GBM) and benign subependymal giant cell astrocytoma (SEGA), pose a serious medical problem. Casein kinase 2 (CK2), a member of the serine/threonine kinase family, has antiapoptotic properties and plays a vital role in glial tumour cell survival. It contributes...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：10.5114/fn.2019.88452
更新日期：2019-01-01 00:00:00
abstract：:Genetic variants that confer susceptibility to Parkinson's disease (PD) show unbalanced distribution among different populations; genetic predisposition to either familial or sporadic forms of PD in Mexican-mestizo population has not been comprehensively studied. The aim of the present study was to analyze genetic var...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：10.5114/fn.2014.41741
更新日期：2014-01-01 00:00:00
abstract：:The effect of transient, global cerebral ischemia on the distribution of endothelin (ET) in blood-brain barrier (BBB) in CA1 area of hippocampus long-time after ischemia was estimated using post-embedding immunogold technique. ET-like immunoreactivity as a gold particles was localized in all compartments of the blood-...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:We report here the first description of florid plaques--the hallmark of variant Creutzfeldt-Jakob disease (vCJD). These plaques are composed of broad bundles of amyloid, are highly neuritic and exhibited astrocytes and microglial cells. Collectively, they are more similar to neuritic plaques of Alzheimer's disease tha...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND AND STUDY PURPOSE:due to the fact that an interrelation between metastases of lung cancer to the brain and surroundings may influence the prognosis, we made attempts to answer the following questions: 1) how is the border between the tumour and its surroundings formed? 2) are there any differences in the gli...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
