Electrical impedance myography discriminates congenital muscular dystrophy from controls.

abstract：:Skeletal muscle fibers from dystrophic mice and littermate controls (ReJ-129) were characterized electrically and then injected with an intracellular marker. In this way they could be identified for examination with an electron microscope to correlate the relative time course of electrical and ultrastructural alterati...

journal_title：Muscle & nerve

authors： Kerr LM,Sperelakis N

更新日期：1983-01-01 00:00:00

abstract：:n-Hexane neuropathy was studied in 20 workers exposed for prolonged periods to this solvent, and with urinary 2,5-hexanedione concentrations exceeding the biological exposure index recommended by the American Conference of Governmental Industrial Hygienists (5 mg/L) with a mean of 11.02 mg/L (range 5.3-24.2 mg/L). Alt...

journal_title：Muscle & nerve

authors： Pastore C,Marhuenda D,Marti J,Cardona A

更新日期：1994-09-01 00:00:00

abstract：INTRODUCTION:While current exercise guidelines recommend progressive, high-intensity resistance training (RT) to promote muscle hypertrophy and strength gains, controversy exists regarding the efficacy of lighter-load RT. We compared 2 work-matched RT interventions that differed in training intensity. METHODS:Fifteen ...

journal_title：Muscle & nerve

authors： Alegre LM,Aguado X,Rojas-Martín D,Martín-García M,Ara I,Csapo R

更新日期：2015-01-01 00:00:00

abstract：:Type-specific antibodies to the polymorphic types of collagen have been used to study their distribution in polymyositis. Dramatic increases were observed in the staining with antibodies to Type III collagen and, to a lesser extent, with antibodies to Types I, IV, and V. The changes in capillary and endomysial basemen...

journal_title：Muscle & nerve

authors： Duance VC,Black CM,Dubowitz V,Hughes GR,Bailey AJ

更新日期：1980-11-01 00:00:00

abstract：INTRODUCTION:Mutations in gap junction protein beta 1 (GJB1) on the X chromosome represent one of the most common causes of hereditary neuropathy. We assessed manifestations associated with a rare 3' untranslated region mutation (UTR) of GJB1 in a large family with X-linked Charcot-Marie-Tooth disease (CMTX). METHODS:...

journal_title：Muscle & nerve

authors： Chen DH,Ma M,Scavina M,Blue E,Wolff J,Karna P,Dorschner MO,Raskind WH,Bird TD

更新日期：2018-05-01 00:00:00

abstract：:The frequency of a recently described point mutation of the ciliary neurotrophic factor (CNTF) gene was investigated in a population of 154 German patients with motor neuron disease (MND). Twenty-two percent of the patients were heterozygous, 2% homozygous for the CNTF mutation. Since the gene defect is per se not lin...

journal_title：Muscle & nerve

authors： Giess R,Goetz R,Schrank B,Ochs G,Sendtner M,Toyka K

更新日期：1998-02-01 00:00:00

abstract：INTRODUCTION:Magnetic resonance imaging (MRI) is an excellent imaging modality for soft tissues. Magnetization transfer (MT) imaging is an MRI technique that is sensitive to the bound protons of macromolecules and therefore can aid in the assessment of nerve damage. METHODS:Measurements of the MT ratio (MTR), which pr...

journal_title：Muscle & nerve

authors： Gambarota G,Krueger G,Theumann N,Mekle R

更新日期：2012-01-01 00:00:00

abstract：:Motor involvement in acute herpes zoster is considered rare, but its incidence is unknown. In a sample of 40 patients with acute herpes zoster of varying severity, an abnormal electromyogram (EMG) (fibrillation, positive waves, high-frequency discharges) was found in 21 (53%), suggesting extension of inflammation to t...

journal_title：Muscle & nerve

authors： Haanpää M,Häkkinen V,Nurmikko T

更新日期：1997-11-01 00:00:00

abstract：:The origins of impaired finger and hand function were examined in 10 stroke survivors with chronic spastic hemiparesis, with the intent of assessing whether mechanical restraint or altered neurophysiological control mechanisms are responsible for the well-known impairment of finger extension. Simultaneous extension of...

journal_title：Muscle & nerve

authors： Kamper DG,Harvey RL,Suresh S,Rymer WZ

更新日期：2003-09-01 00:00:00

abstract：INTRODUCTION:Despite structural distinction between the transverse and oblique heads of the adductor pollicis, in vivo testing continues to consider the adductor pollicis as functionally simplistic. As a muscle's architecture is a strong indicator of function, in this study we aimed to determine whether the physiologic...

journal_title：Muscle & nerve

authors： Stamenkovic A,Munro BJ,Peoples GE

更新日期：2014-03-01 00:00:00

abstract：:As caveolin-3 deficiencies may explain persistent hyper-CK-emia, we performed CAV3 gene mutation analysis and immunohistochemistry for caveolin-3 in 31 patients with idiopathic hyper-CK-emia. In 2 of 29 patients who donated blood, variants in the CAV3 gene were detected. Although immunohistochemical analysis strongly ...

journal_title：Muscle & nerve

authors： Reijneveld JC,Ginjaar IB,Frankhuizen WS,Notermans NC

更新日期：2006-11-01 00:00:00

abstract：:Microdrop samples of endoneurial fluid and serum from galactosemic rats were analyzed with energy dispersive spectrometry (EDS). The sodium concentration of endoneurial fluid from galactose-fed rats (295 meq/liter) was nearly twice that of age-matched controls (152 meq/liter) and indicates that sodium is present in an...

journal_title：Muscle & nerve

authors： Mizisin AP,Myers RR,Powell HC

更新日期：1986-06-01 00:00:00

abstract：:Sucrose gap and intra-axonal recording techniques were used to identify the types of ion channels and inward rectification that are present in regenerated axons of adult (greater than 8 weeks) rat sciatic nerve after crush injury. In sucrose gap recordings, 4-aminopyridine (4-AP) led to slight broadening of the compou...

journal_title：Muscle & nerve

authors： Gordon TR,Kocsis JD,Waxman SG

更新日期：1991-07-01 00:00:00

abstract：:The presence of differences in motor unit activity across contraction types and between hands suggests that the magnitude of fluctuations in motor output is only weakly related when these conditions are compared. Twenty right-handed young (24.1 +/- 5.3 years) and old (72.5 +/- 4.9 years) adults performed three levels ...

journal_title：Muscle & nerve

authors： Shinohara M,Keenan KG,Enoka RM

更新日期：2005-06-01 00:00:00

abstract：:The selection of patients who will benefit from peripheral nerve surgery continues to evolve. The evaluation of patients with peripheral nerve problems, and the indications and timing of surgery are reviewed. This includes patients with transections, lesions in continuity, entrapments, tumors, injection injuries, and ...

journal_title：Muscle & nerve

authors： Spinner RJ,Kline DG

更新日期：2000-05-01 00:00:00

abstract：INTRODUCTION:Onabotulinum toxin serotype A (BT-A) is used for a variety of motor and sensory disorders related to abnormal muscle activity. METHODS:We developed a high-resolution rodent model to allow precise determination of the effect of BT-A dose (measured in units) and injectate volume (measured in μl) on the effi...

journal_title：Muscle & nerve

authors： Hulst JB,Minamoto VB,Lim MB,Bremner SN,Ward SR,Lieber RL

更新日期：2014-05-01 00:00:00

abstract：:A treatment has been developed to alleviate muscle weakness in murine dystrophy. Cultured myoblasts from genetically normal mouse embryos were injected into the right soleus of 20-day-old normal or dystrophic mice. Hosts and donors were immunocompatible but exhibited different genotype markers. Donor cells produced GP...

journal_title：Muscle & nerve

authors： Law PK,Goodwin TG,Wang MG

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:In adult males, cross-sectional area (CSA) for type II muscle fibers is generally larger than for type I fibers. In this cross-sectional study the aim was to compare sex-related CSAs of various muscle fiber types during childhood-to-adulthood transition. METHODS:Percutaneous biopsy samples were obtained fro...

journal_title：Muscle & nerve

authors： Esbjörnsson ME,Dahlström MS,Gierup JW,Jansson EC

更新日期：2020-12-21 00:00:00

abstract：INTRODUCTION:The objective of this study was to identify the pattern of neurological deficits and document electrophysiological changes in women with macromastia. METHODS:Patients with macromastia and neurological complaints underwent clinical evaluation and electrodiagnostic (EDx) studies of the upper limbs. RESULTS...

journal_title：Muscle & nerve

authors： Ansell JR,Buchholz MC

更新日期：2013-02-01 00:00:00

abstract：:Left spinal accessory nerve palsy occurred in a young man when he quickly turned his head to the right while his shoulders were pulled down by heavy hand-held objects. Electrophysiologic studies demonstrated partial axonotmesis of the spinal accessory nerve branches innervating the sternocleidomastoid and upper and mi...

journal_title：Muscle & nerve

authors： Logigian EL,McInnes JM,Berger AR,Busis NA,Lehrich JR,Shahani BT

更新日期：1988-02-01 00:00:00

abstract：INTRODUCTION:Stroke-related changes in maximal dynamic hip flexor muscle fatigability may be more relevant functionally than isometric hip flexor fatigability. METHODS:Ten chronic stroke survivors performed 5 sets of 30 hip flexion maximal dynamic voluntary contractions (MDVC). A maximal isometric voluntary contractio...

journal_title：Muscle & nerve

authors： Kuhnen HR,Rybar MM,Onushko T,Doyel RE,Hunter SK,Schmit BD,Hyngstrom AS

更新日期：2015-03-01 00:00:00

abstract：:Data are scarce relating to the plasticity with strength training of dynamic muscle performance in older humans. Hence, we investigated alterations in the torque-velocity relation with strength training in old age, and their origin. Knee extension and leg-press exercises were performed three times per week for 14 week...

journal_title：Muscle & nerve

authors： Reeves ND,Maganaris CN,Narici MV

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:Nebulin is a giant actin-binding protein in the thin filament of the skeletal muscle sarcomere. Studies of nebulin interactions are limited by the size, complexity, and poor solubility of the protein. We divided the nebulin super-repeat region into a super-repeat panel, and studied nebulin/actin interactio...

journal_title：Muscle & nerve

authors： Laitila J,Lehtonen J,Lehtokari VL,Sagath L,Wallgren-Pettersson C,Grönholm M,Pelin K

更新日期：2019-01-01 00:00:00

abstract：:Acetylcholine receptor (AChR) metabolism was studied in muscle from juvenile and adult dogs with congenital myasthenia gravis (CMG) and their unaffected littermates. Although the amount of AChR in the junctional region of innervated CMG muscle fibers was 25% of normal, or less, denervation of CMG fibers resulted in th...

journal_title：Muscle & nerve

authors： Oda K,Lennon VA,Lambert EH,Palmer AC

更新日期：1984-11-01 00:00:00

abstract：:A 3-month-old boy with hypotonia at birth succumbed to a congenital myopathy. The major finding in his muscle biopsy corresponded to I-Z-I complexes described previously in embryonic skeletal muscle. A few previous myopathy cases have described findings suggestive of I-Z-I-like complexes. A mutation affecting mononucl...

journal_title：Muscle & nerve

authors： Rhodes RH,Sharer LR

更新日期：2010-05-01 00:00:00

abstract：INTRODUCTION:The radial nerve and posterior interosseous nerve (PIN) are prone to injury at multiple sites. Electrodiagnostic (EDx) studies may only identify the most proximal lesion. Nerve ultrasound could augment EDx by visualizing additional pathology. METHODS:This investigation was a retrospective examination of u...

journal_title：Muscle & nerve

authors： Dietz AR,Bucelli RC,Pestronk A,Zaidman CM

更新日期：2016-03-01 00:00:00

abstract：:Muscle of donor origin was formed after implantation of H-2Kb-tsA58 muscle precursor cells (mpc) into irradiated mdx nu/nu mouse muscles. A series of injections of the myotoxin, notexin, which destroys mature muscle fibers but spares muscle precursor cells and other tissues, was made into the mpc-injected muscles, lea...

journal_title：Muscle & nerve

authors： Gross JG,Morgan JE

更新日期：1999-02-01 00:00:00

abstract：:The lack of effective therapy for many of the chronic neuromuscular diseases such as amyotrophic lateral sclerosis, hereditary motor sensory neuropathy (Charcot-Marie-Tooth disease), spinocerebellar degenerations and idiopathic polyneuropathy has led to a search for substances that may stimulate peripheral nerve regen...

journal_title：Muscle & nerve

authors： Bradley WG

更新日期：1990-09-01 00:00:00

abstract：:Electromyographic (EMG) recordings may serve an important role in predicting torque during repetitive activation of paralyzed muscle. We compared the initial M-wave to the subsequent M-waves of the same train under fatigued and recovered conditions in the paralyzed human soleus muscle. Sixteen individuals with chronic...

journal_title：Muscle & nerve

authors： Chang YJ,Shields RK

更新日期：2002-11-01 00:00:00

abstract：INTRODUCTION:Cachexia increases morbidity and mortality of cancer patients. The progressive loss of muscle mass negatively affects physical function and quality of life. We previously showed reduced muscle insulin-like growth factor-1 (IGF-1) expression and enhanced myostatin signaling in tumor-bearing animals. This st...

journal_title：Muscle & nerve

authors： Bonetto A,Penna F,Aversa Z,Mercantini P,Baccino FM,Costelli P,Ziparo V,Lucia S,Rossi Fanelli F,Muscaritoli M

更新日期：2013-09-01 00:00:00