Abstract：
:Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2, is a disaster due to not only its psychosocial impact but it also to its direct effects on the brain. The latest evidence suggests it has neuroinvasive mechanisms, in addition to neurological manifestations, and as seen in past pandemics, long-term sequelae are expected. Specific and well-structured interventions are necessary, and that's why it's important to ensure a continuity between primary care, emergency medicine, and psychiatry. Evidence shows that 2003 SARS (Severe Acute Respiratory Syndrome) survivors developed persistent psychiatric comorbidities after the infection, in addition to Chronic Fatigue Syndrome. A proper stratification of patients according not only to psychosocial factors but also an inflammatory panel and SARS-Cov-2's direct effects on the central nervous system (CNS) and the immune system, may improve outcomes. The complexity of COVID-19's pathology and the impact on the brain requires appropriate screening that has to go beyond the psychosocial impact, taking into account how stress and neuroinflammation affects the brain. This is a call for a clinical multidisciplinary approach to treat and prevent Sars-Cov-2 mental health sequelae.
journal_name
J Psychiatr Resjournal_title
Journal of psychiatric researchauthors
Pallanti S,Grassi E,Makris N,Gasic GP,Hollander Edoi
10.1016/j.jpsychires.2020.08.008subject
Has Abstractpub_date
2020-11-01 00:00:00pages
215-217eissn
0022-3956issn
1879-1379pii
S0022-3956(20)30919-5journal_volume
130pub_type
杂志文章,评审abstract：:Generalized anxiety disorder (GAD) is highly prevalent among adolescents. An early detection of individuals at risk may prevent later psychiatric condition. Genome-wide studies investigating single nucleotide polymorphisms (SNPs) concluded that a focus on epigenetic mechanisms, which mediate the impact of environmenta...
journal_title：Journal of psychiatric research
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更新日期：2018-07-01 00:00:00
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journal_title：Journal of psychiatric research
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journal_title：Journal of psychiatric research
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2017.02.018
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journal_title：Journal of psychiatric research
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doi：10.1016/j.jpsychires.2012.09.002
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journal_title：Journal of psychiatric research
pub_type： 杂志文章,评审
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2020.06.002
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2006.04.008
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2011.10.004
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/0022-3956(95)00009-t
更新日期：1995-05-01 00:00:00
abstract：BACKGROUND:Although, a large population-based literature exists on the relationship between childhood adversity and Axis I mental disorders, research on the link between childhood adversity and Axis II personality disorders (PDs) relies mainly on clinical samples. The purpose of the current study was to examine the rel...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2010.11.008
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/s0022-3956(01)00017-6
更新日期：2001-05-01 00:00:00
abstract：:Schizophrenic patients are known to experience difficulties in emotional information processing, yet knowledge of their physiological responsivity to emotional stimuli is limited. The purpose of this study was to investigate the physiological reactions of schizophrenic patients to emotional stimuli. We presented pictu...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2004.11.004
更新日期：2005-09-01 00:00:00
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2005.10.009
更新日期：2007-01-01 00:00:00
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2008.10.009
更新日期：2009-05-01 00:00:00
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2020.02.006
更新日期：2020-04-01 00:00:00
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/0022-3956(91)90022-3
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2017.04.010
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2010.03.015
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2020.11.017
更新日期：2020-11-09 00:00:00
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2015.05.018
更新日期：2015-09-01 00:00:00
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2006.02.010
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abstract：:Cannabis use is associated with onset of psychosis in individuals vulnerable for developing schizophrenia-spectrum disorders. The present study addressed three knowledge gaps pertaining to this issue: 1) clarifying the incidence of cannabis use in schizotypal individuals, 2) examining how cannabis use is related to ps...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2010.08.013
更新日期：2011-04-01 00:00:00
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2018.09.001
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abstract：:HLA antigens were typed among 24 schizophrenic, 13 schizoaffective and 246 control subjects. Schizoaffective patients showed significantly decreased incidence of A2 compared with schizophrenic patients or controls. ...
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pub_type： 杂志文章
doi：10.1016/0022-3956(85)90076-7
更新日期：1985-01-01 00:00:00
abstract：:Deficits in sensorimotor gating, as measured with prepulse inhibition (PPI), have been considered an endophenotype of schizophrenia. However, the question remains whether these deficits are related to current symptoms. This single site study aimed to explore clinical features related to the modulation of startle refle...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2016.07.026
更新日期：2016-11-01 00:00:00
