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Circulating cytokines in Alzheimer's disease.

Abstract：

:Immune factors may be involved in the pathophysiology of Alzheimer's disease (AD), a neurodegenerative disease. Since immune activation precedes immune-mediated processes, we measured plasma levels of four selective cytokines: interleukin-6 (IL-6), interleukin-12 (IL-12), interferon-alpha (IFN-alpha), and interferon-gamma (IFN-gamma). The level of IL-6, but not other cytokines, was significantly elevated. The increase of circulating IL-6 indicates immune activation presumably related to pathophysiology of the disease.

journal_name

J Psychiatr Res

journal_title

Journal of psychiatric research

authors

Singh VK,Guthikonda P

doi

10.1016/s0022-3956(97)00023-x

subject

Has Abstract

pub_date

1997-11-01 00:00:00

pages

657-60

issue

6

eissn

0022-3956

issn

1879-1379

pii

S002239569700023X

journal_volume

31

pub_type

杂志文章

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