Mitochondria targeting nano agents in cancer therapeutics.

abstract：:The aim of the present study was to evaluate the curative effect of fludeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT)-guided intensity-modulated radiotherapy (IMRT) for 42 patients with International Federation of Gynecology and Obstetrics (FIGO) stage III/IV ovarian cancer. Between Jan...

journal_title：Oncology letters

authors： Dang YZ,Li X,Ma YX,Li XL,Yang T,Lu WL,Huang SG

更新日期：2019-01-01 00:00:00

abstract：:Cancer affects multiple organs in the body Malignant melanoma involves the invasion of skin and occasionally mucosal membrane or eye choroidal tissues. The incidence of cutaneous malignant melanoma is on the increase worldwide and is a major concern in current research. The increase is associated with UV irradiation-i...

journal_title：Oncology letters

authors： Zhang XY,Zhang PY

更新日期：2016-11-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is rare in the adult population and even rarer with jaw involvement. The current study presents the case of a 39-year-old male who complained of recurrent pain, swelling of the gingiva and an occasional pus-like discharge in the right mandible for one year. The patient was previousl...

journal_title：Oncology letters

authors： Shi S,Liu Y,Fu T,Li X,Zhao S

更新日期：2014-09-01 00:00:00

abstract：:In the present study, the function and mechanism of cytokine-induced killer cells (CIK) combined with dendritic cells (DC-CIK) were examined in Lewis lung cancer (LLC) cells. Co-culture of CIK dendritic cells (DC) in vitro was used to investigate their proliferation and the antitumor effects on LLC cells. DC and CIK c...

journal_title：Oncology letters

authors： Hou Y,Zang D,Li X,Li F

更新日期：2018-08-01 00:00:00

abstract：:Inhibition of nuclear factor-κB (NF-κB) results in antitumor activity in leukemia cells, and may be a potential therapeutic strategy for the treatment of leukemia. However, a significant limitation of NF-κB inhibition in the treatment of leukemia is the low efficiency of this technique. NF-κB inhibitor treatment induc...

journal_title：Oncology letters

authors： Dong QM,Ling C,Chen X,Zhao LI

更新日期：2015-12-01 00:00:00

abstract：:The aim of the present study was to identify a specific biological marker for the diagnosis of colorectal adenomas through the analysis of variations in serum protein profiling in colorectal adenoma patients. The study was conducted at the Renmin Hospital of Wuhan University (Wuhan, China) between September 2011 and M...

journal_title：Oncology letters

authors： Zhou ZY,Tao DD,Cao JW,Luo HS

更新日期：2013-06-01 00:00:00

abstract：:Management of multinodular hepatocellular carcinoma (HCC) in the intermediate Barcelona Clinic Liver Cancer (BCLC)-B stage is controversial. The aim of the present study as to identify the subgroup of patients with BCLC-B HCC who could benefit from liver resection. The present study retrospectively analyzed the outcom...

journal_title：Oncology letters

authors： Matsukuma S,Sakamoto K,Tokuhisa Y,Tokumitsu Y,Matsui H,Kanekiyo S,Tomochika S,Iida M,Suzuki N,Takeda S,Ueno T,Wada H,Kobayashi S,Saeki I,Eguchi H,Sakon M,Sakaida I,Nagano H

更新日期：2018-11-01 00:00:00

abstract：:Ovarian cancer (OC) is the most common and lethal gynecologic malignancy. The pathophysiology of OC tumor development is complex and involves numerous biological pathways. Previous studies suggest that circular (circ)RNAs serve important roles in OC tumor pathology. In the present study, a re-annotation strategy was p...

journal_title：Oncology letters

authors： Guo Q,He Y,Sun L,Kong C,Cheng Y,Zhang G

更新日期：2019-04-01 00:00:00

abstract：:Intramuscular myxoma (IM) is a benign intramuscular neoplasm composed of fibroblasts and abundant myxoid stroma. IMs most commonly affect larger skeletal muscles, while those affecting the oral and maxillofacial regions are rare, with a small number of documented cases in the available literature. The aim of the prese...

journal_title：Oncology letters

authors： Li G,Jiang W,Li W,Li J

更新日期：2014-05-01 00:00:00

abstract：:In this study, we report the cytogenetic analysis of a 31-year-old male with a rare translocation between chromosomes 1 and 16 and inversion of chromosome 5 in CD99-positive soft tissue sarcoma of the thigh, which metastasized to the lung. Histologically, the tumor showed ovoid or short-spindle atypical cells with pos...

journal_title：Oncology letters

authors： Kanamori M,Suzuki K,Yasuda T,Hori T

更新日期：2012-06-01 00:00:00

abstract：:The occurrence of primary carcinoma of the ureteral stump following radical nephrectomy for renal cell carcinoma is extremely rare; 7 patients with the disease have been reported previously. All these patients were males with transitional cell carcinoma. The current study reports the case of a 61-year-old woman, who p...

journal_title：Oncology letters

authors： Jin S,Wang G,Yu C,Li N

更新日期：2016-05-01 00:00:00

abstract：:Polydatin, extracted from Polygonum cuspidatum, is known for its anti-platelet aggregation and anti-inflammatory effects. However, studies on the association of polydatin with cancer are limited, particularly with regards to epithelial-mesenchymal transition (EMT)-associated migration and invasion of cancer cells. The...

journal_title：Oncology letters

authors： Jiang J,Chen Y,Dong T,Yue M,Zhang Y,An T,Zhang J,Liu P,Yang X

更新日期：2019-05-01 00:00:00

abstract：:MicroRNA (miRNA/miR) dysfunction is a hallmark of lung cancer, and results in the dysregulation of tumor suppressors and oncogenes during lung cancer progression. Selection of the 5p and 3p arms of miRNA is a mechanism that improves the modulation of miRNA biological functions and complicates the regulatory network in...

journal_title：Oncology letters

authors： Lin MH,Chen YZ,Lee MY,Weng KP,Chang HT,Yu SY,Dong BJ,Kuo FR,Hung LT,Liu LF,Chen WS,Tsai KW

更新日期：2018-06-01 00:00:00

abstract：:5-lipoxygenase (5-LO) catalyzes the first step of arachidonic acid metabolism to inflammatory mediator leukotrienes. The present study assessed 5-LO expression in esophageal squamous cell carcinoma (ESCC) tissue specimens for associations with clinicopathological and survival data from patients, then explored 5-LO act...

journal_title：Oncology letters

authors： Bai CY,Zhang JY,Shi TW,Bai YQ,Wu BL,Du ZP,Wu ZY,Xu XE,Wang SH,Wu JY,Te RY,Zhang JY,Xu LY,Li EM

更新日期：2018-06-01 00:00:00

abstract：:Previous studies have demonstrated an association between human papillomavirus (HPV) and mutations in the epidermal growth factor receptor (EGFR) gene in lung cancer patients; however, few studies have investigated this association in advanced lung adenocarcinoma patients undergoing gefitinib treatment. The present st...

journal_title：Oncology letters

authors： Li M,Deng F,Qian LT,Meng SP,Zhang Y,Shan WL,Zhang XL,Wang BL

更新日期：2016-09-01 00:00:00

abstract：:While erlotinib is primarily administered to patients with non-small cell lung cancer with sensitizing epidermal growth factor receptor (EGFR) mutations, it is also prescribed to patients with wild type (wt) EGFR in higher lines of treatment. However, there is no predictive marker for erlotinib efficacy in patients wi...

journal_title：Oncology letters

authors： Svaton M,Fiala O,Krakorova G,Blazek J,Hurdalkova K,Barinova M,Mukensnabl P,Pesek M

更新日期：2020-08-01 00:00:00

abstract：:Evidence-based guidelines for the prevention of surgical site infection (SSI) have been published by the U.S. Centers for Disease Control and Prevention (CDC). According to these guidelines, a wound should usually be covered with a sterile dressing for 24 to 48 h when a surgical incision is closed primarily. However, ...

journal_title：Oncology letters

authors： Akagi I,Furukawa K,Miyashita M,Kiyama T,Matsuda A,Nomura T,Makino H,Hagiwara N,Takahashi K,Uchida E

更新日期：2012-07-01 00:00:00

abstract：:MicroRNA (miR)-204-5p was previously identified to be downregulated in melanoma compared with melanocytic nevi. This observation prompted a functional study on miR-204-5p and the newly-identified miR-3065-5p, two miRNAs suggested to be tumor-suppressive oncomiRs. Application of miR-204-5p mimics or inhibitors resulted...

journal_title：Oncology letters

authors： Palkina N,Komina A,Aksenenko M,Moshev A,Savchenko A,Ruksha T

更新日期：2018-06-01 00:00:00

abstract：:Lysine-specific demethylase 1 (LSD1) functions as a transcriptional coregulator by modulating histone methylation and has been associated with numerous high-risk cancers. Previously, our group and others identified LSD1 as an upregulated gene in ovarian cancer, and reported that the upregulation of LSD1 was associated...

journal_title：Oncology letters

authors： Shao G,Wan X,Lai W,Wu C,Jin J,Liu X,Wei Y,Lin Q,Zhang L,Shao Q

更新日期：2018-06-01 00:00:00

abstract：:Synovial sarcoma is a rare, highly malignant soft-tissue tumor that occurs primarily in the extremities. At present, there is no effective clinical treatment for this condition. The present study reports the case of a 49-year-old male who was diagnosed with pleural synovial sarcoma and treated with recombinant human e...

journal_title：Oncology letters

authors： Teng C,Li LI,Shen W,Li J,Liu Y,Jiang Q,Xin T,Huang D,Song X,Lv Y,Jin Y

更新日期：2015-08-01 00:00:00

abstract：:The incidence of breast cancer is increasing throughout the world. Although significant progress has been made in diagnostic techniques and targeted therapies, the prognosis of breast cancer remains poor. Regulator of differentiation 1 (ROD1) may inhibit the development of several types of cancer. However, the role of...

journal_title：Oncology letters

authors： Zhou Y,Zou H,Wu E,Huang L,Yin R,Mei Y,Zhu X

更新日期：2018-08-01 00:00:00

abstract：:Berberine is sourced from multiple medicinal herb resources and is easy to extract. With the advantages of low price, safety and convenience, berberine may have potential for wide clinical use. The present study aimed to investigate whether berberine inhibited the viability of colon cancer and whether it regulated the...

journal_title：Oncology letters

authors： Lü Y,Han B,Yu H,Cui Z,Li Z,Wang J

更新日期：2018-04-01 00:00:00

abstract：:Increasing evidence has indicated that the dysregulation of microRNA (miRNA) occur in the pathogenesis of retinoblastoma (RB). Aim of the present study was to investigate the possible role of miR-494 (miR-494-3p) in RB. It was demonstrated that miR-494 expression was increased in RB tissue samples and cell lines. Also...

journal_title：Oncology letters

authors： Xu F,Liu G,Wang L,Wang X,Jin X,Bo W

更新日期：2020-08-01 00:00:00

abstract：:Salidroside is one of the most potent compounds extracted from the plant Rhodiola rosea, and its cardiovascular protective effects have been studied extensively. However, the role of salidroside in human ovarian carcinoma remains unknown. The aim of the current study was to investigate the effects of salidroside on th...

journal_title：Oncology letters

authors： Yu G,Li N,Zhao Y,Wang W,Feng XL

更新日期：2018-05-01 00:00:00

abstract：:Targeted therapy of non-small cell lung cancer (NSCLC) patients with mutations in the epidermal growth factor receptor (EGFR) gene has been associated with improved prognosis. However, there is a shortage on data from real-world clinical practice in management of EGFR-positive NSCLC patients in Poland. The present stu...

journal_title：Oncology letters

authors： Ramlau R,Krawczyk P,Dziadziuszko R,Chmielewska I,Milanowski J,Olszewski W,Stencel K,Ramlau-Piątek K,Segiet A,Skroński M,Grudny J,Chorostowska-Wynimko J

更新日期：2017-11-01 00:00:00

abstract：:The talin proteins are a key component of the extracellular matrix-integrin-cytoskeleton system, and our previous study suggested that talin2 contributes to the tumor invasion and metastasis processes regulated by the tumor microenvironment. In the present study, the specific effects of talin2 on the invasive ability ...

journal_title：Oncology letters

authors： Wen Z,Liang Y,Deng S,Zou L,Xie X,Yang J,Wu Y

更新日期：2019-06-01 00:00:00

abstract：:The present study reported three rare cases of multicystic vestibular schwannoma with fluid-fluid levels. These three tumors exhibited apparent fluid-fluid levels that demonstrated a radiological appearance of two fluid levels in the cystic area. Two cases had an acute history, whereas one case presented with a chroni...

journal_title：Oncology letters

authors： Li P,Bi Z,Hao S,Zhang J

更新日期：2015-07-01 00:00:00

abstract：:The aim of the present study was to determine the impact of obesity on radiation-induced gastrointestinal (GI) and genitourinary (GU) toxicity. The cases of 54 patients with prostate cancer, treated with three-dimensional conformal radiation therapy (RT), were reviewed. For each patient, the body mass index (BMI), dis...

journal_title：Oncology letters

authors： Doi H,Ishimaru F,Tanooka M,Inoue H,Odawara S,Takada Y,Niwa Y,Fujiwara M,Kamikonya N,Yamamoto S,Hirota S

更新日期：2014-01-01 00:00:00

abstract：:Herpesvirus entry mediator (HVEM) displays dual signals in T-cell activation according to the ligands and intracytoplasmic effectors it interacts with. High HVEM expression may play an immunosuppressive role in several malignancies. The present study investigated the clinical impact of HVEM on intrahepatic cholangioca...

journal_title：Oncology letters

authors： Ma B,Meng H,Tian Y,Wang Y,Song T,Zhang T,Wu Q,Cui Y,Li H,Zhang W,Li Q

更新日期：2021-01-01 00:00:00

abstract：:The current study reports the case of a large retroperitoneal tumor treated with modified simultaneous integrated boost (SIB) radiotherapy. A 45-year-old female presented to the emergency department complaining of left abdominal pain and fever. A computed tomography scan detected a retroperitoneal tumor of 12×16×16 cm...

journal_title：Oncology letters

authors： Nomiya T,Akamatsu H,Harada M,Ota I,Hagiwara Y,Ichikawa M,Miwa M,Mizutani M,Kato T,Nagaoka A,Tomita Y,Nemoto K

更新日期：2015-06-01 00:00:00