Abstract:
:Synovial sarcoma is a rare, highly malignant soft-tissue tumor that occurs primarily in the extremities. At present, there is no effective clinical treatment for this condition. The present study reports the case of a 49-year-old male who was diagnosed with pleural synovial sarcoma and treated with recombinant human endostatin (Endostar) combined with chemotherapy for a total of six cycles, followed by sunitinib maintenance therapy. To the best of our knowledge, this is the first reported use of sunitinib for maintenance therapy in pleural synovial sarcoma. The patient survived for 25 months after the recurrence of the disease following surgery. The results indicate that this combination therapy was effective in the treatment of pleural synovial sarcoma. The present study also briefly reviews the literature on pleural synovial sarcoma, and the features and treatments for this rare case are discussed.
journal_name
Oncol Lettjournal_title
Oncology lettersauthors
Teng C,Li LI,Shen W,Li J,Liu Y,Jiang Q,Xin T,Huang D,Song X,Lv Y,Jin Ydoi
10.3892/ol.2015.3311subject
Has Abstractpub_date
2015-08-01 00:00:00pages
1141-1144issue
2eissn
1792-1074issn
1792-1082pii
OL-0-0-3311journal_volume
10pub_type
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