Value of shear wave elastography in the diagnosis and evaluation of cervical cancer.

abstract：:The clinical significance of the proteasome inhibitor MG132 has been examined in numerous human cancer types; however, its influence on the metastasis and progression of pancreatic cancer is yet to be determined. In the present study, the effect of MG132 treatment on pancreatic ductal adenocarcinoma (PDAC) cell lines ...

journal_title：Oncology letters

authors： Jin F,Xiao D,Zhao T,Yu M

更新日期：2020-01-01 00:00:00

abstract：:This study investigated the mRNA levels of thymidylate synthetase (TYMS) and dihydropyrimidine dehydrogenase (DPYD) in esophageal squamous cell carcinoma (ESCC). TYMS and DPYD gene expression was quantified using real-time RT-PCR in 56 patients with ESCC, co-amplified with glyceraldehyde-3-phosphate dehydrogenase as a...

journal_title：Oncology letters

authors： Kimura M,Kuwabara Y,Mitsui A,Ishiguro H,Sugito N,Tanaka T,Shiozaki M,Naganawa Y,Takeyama H

更新日期：2011-03-01 00:00:00

abstract：:This study aims to comparatively analyze the impact of laparoscopic myomectomy (LM) and transcervical resection of myoma (TCRM) on ovarian function, immune function and quality of sexual life of patients with hysteromyoma. Two hundred and forty patients with hysteromyoma admitted into the Second Affiliated Hospital of...

journal_title：Oncology letters

authors： Zhang Y,Gu X,Meng Y,Guo H,Du J,Xing W

更新日期：2018-03-01 00:00:00

abstract：:A 39-year-old female presented to The First Affiliated Hospital of Jishou University (Jishou, Hunan) with a fever of unknown origin and progressive abdominal distension. Physical examination revealed generalized lymphadenopathy, multiple non-tender cutaneous nodules, hepatomegaly, splenomegaly and abdominal edema. An ...

journal_title：Oncology letters

authors： Song K,Li M

更新日期：2015-05-01 00:00:00

abstract：:The expression of macrophage inhibitory cytokine-1 (MIC-1) of early gastric cancer treated using endoscopic mucosal resection (EMR) and its correlation with prognosis were investigated. One hundred and forty-seven patients with early gastric cancer (less than 20 mm in diameter) were recruited and assigned into an obse...

journal_title：Oncology letters

authors： Zhang N,Lu B

更新日期：2017-08-01 00:00:00

abstract：:SIRT6, is a member of the NAD-dependent sirtuin family of enzymes, and has been reported as a novel tumor suppressor gene or oncogene, dependent on the type of cancer. However, the role of SIRT6 in osteosarcoma has not been investigated. The present study demonstrated that the expression of SIRT6 was downregulated in ...

journal_title：Oncology letters

authors： Gao Y,Qu Y,Zhou Q,Ma Y

更新日期：2019-01-01 00:00:00

abstract：:A 72-year-old man initially presented with lumbar and right chest pain, but was later found out to also have an elevated prostate-specific antigen (PSA) level at 2,000.0 ng/ml. Further evaluation disclosed metastatic prostate cancer involving the bones and lymph nodes. The patient was initially treated with combined a...

journal_title：Oncology letters

authors： Kato T,Komiya A,Yuasa J,Kaga K,Kaga M,Kojima S,Naya Y,Isaka S

更新日期：2018-02-01 00:00:00

abstract：:Breast cancer is a highly heterogeneous disease at the molecular level and >90% of mortalities are due to metastasis and its associated complications. The present study determined the impact of molecular subtypes on metastatic behavior and overall survival (OS) of patients with metastatic breast cancer. The influence ...

journal_title：Oncology letters

authors： Yang H,Wang R,Zeng F,Zhao J,Peng S,Ma Y,Chen S,Ding S,Zhong L,Guo W,Wang W

更新日期：2020-10-01 00:00:00

abstract：:The purpose of this study was to present the results of fertility-sparing treatment using medroxyprogesterone acetate (MPA) for endometrial carcinoma (EC), and to clarify patient characteristics by investigating patient background factors. A total of 59 patients with EC, who received MPA as fertility-sparing therapy a...

journal_title：Oncology letters

authors： Fujiwara H,Jobo T,Takei Y,Saga Y,Imai M,Arai T,Taneichi A,Machida S,Takahashi Y,Suzuki M

更新日期：2012-05-01 00:00:00

abstract：:Colon cancer is the second most common type of cancer in females and the third in males, worldwide. The most common sites of colon cancer metastasis are the regional lymph nodes, liver, lung, bone and brain. In this study, an extremely rare case of colon adenocarcinoma with extensive metastasis to the mediastinal lymp...

journal_title：Oncology letters

authors： El-Halabi MM,Chaaban SA,Meouchy J,Page S,Salyers WJ Jr

更新日期：2014-11-01 00:00:00

abstract：:Breast cancer is a leading cause of cancer-associated mortality in females worldwide and evidence suggests that human cytomegalovirus (HCMV) infection may be implicated in the progress of breast cancer. HCMV glycoprotein B (gB) is the most abundant envelope protein and serves an important role in host cell entry. The ...

journal_title：Oncology letters

authors： Yang R,Liang J,Xu GX,Ding LM,Huang HM,Su QZ,Yan J,Li YC

更新日期：2018-05-01 00:00:00

abstract：:Peroxiredoxin (Prx) II is an imperative member of the superfamily of peroxidases. It serves an essential role in scavenging organic hydroperoxide and H2O2. It is involved in the development of various malignant tumors. In order to investigate the significance of Prx II expressions level in gastric cancer (GC), downreg...

journal_title：Oncology letters

authors： Niu L,Liu A,Xu W,Yang L,Zhu W,Gu Y

更新日期：2018-10-01 00:00:00

abstract：:Chronic myelogenous leukemia (CML) is a common hematological malignancy. Some patients progressing to the blast phase develop chemotherapeutic drug resistance. In the authors' previous study, it was found that the mammalian target of rapamycin (mTOR) pathway was activated in CML and that rapamycin inhibited the prolif...

journal_title：Oncology letters

authors： Li J,Liu W,Hao H,Wang Q,Xue L

更新日期：2019-09-01 00:00:00

abstract：:The geldanamycin derivative 17-allylamino-17-demethoxygeldanamycin (17-AAG) is known to induce internalisation and degradation of the otherwise internalisation-resistant human epidermal growth factor receptor 2 (HER2) receptor. In the present study, 17-AAG was used to increase internalisation of the HER2-specific Affi...

journal_title：Oncology letters

authors： Göstring L,Lindegren S,Gedda L

更新日期：2016-10-01 00:00:00

abstract：:It is crucial to classify cervical lesions into high-grade squamous intraepithelial lesions (HSILs) and low-grade SILs (LSILs), as LSILs are conservatively treated by observation, based on an expectation of natural regression, whereas HSILs usually require electrosurgical excision. In the present study, peripheral blo...

journal_title：Oncology letters

authors： Zou C,Lyu Y,Jiang J,Cao Y,Wang M,Sang C,Zhang R,Li H,Liew CC,Cheng C,Zhao S

更新日期：2020-09-01 00:00:00

abstract：:The primary goal of radiotherapy in oncology is to enhance the efficacy of tumor cell death while decreasing damage to surrounding normal cells. Positive therapeutic outcomes may be accomplished by improved targeting, precisely targeting tumor cells or protecting normal cells against radiation-induced damage. The pote...

journal_title：Oncology letters

authors： Kim W,Kang J,Lee S,Youn B

更新日期：2017-06-01 00:00:00

abstract：:Clear cell myoepithelial carcinoma is a very rare disease which develops primarily in the parotid gland. To date, only 17 cases of clear cell myoepithelial carcinoma have been reported worldwide. Among them, only three cases developed in the minor salivary gland in the oral cavity. No cases developed in the base of th...

journal_title：Oncology letters

authors： Park JH,Choi JY,Hong R,DO NY

更新日期：2012-12-01 00:00:00

abstract：:Application of dexmedetomidine combined with sufentanil in colon cancer resection and its effect on immune and coagulation function of patients was studied. Colon cancer cases (n=176) admitted to Xiangya Hospital Central South University were selected into the study. They were divided into group A (n=92) and group B (...

journal_title：Oncology letters

authors： Zhao L,Li Y

更新日期：2020-08-01 00:00:00

abstract：:Rare types of cancer are often not effectively treated by approaches such as chemotherapy and radio-therapy, although their side-effects persist. Immunotherapy has been gaining attention worldwide with growing examples of its anticancer activity demonstrated in vivo. This case report describes a 35-year-old male who s...

journal_title：Oncology letters

authors： Ratnavelu K,Subramani B,Pullai CR,Krishnan K,Sugadan SD,Rao MS,Veerakumarasivam A,Deng X,Hiroshi T

更新日期：2013-05-01 00:00:00

abstract：:Natural products are a promising source for the development of novel cancer therapies, due to their potential effectiveness and low toxicity profiles. As a main component of Herba oxytropis, 2',4'-dihydroxychalcone (TFC) is known to demonstrate anti-tumor activity in vitro. In the present study, TFC was found to potent...

journal_title：Oncology letters

authors： Sheng Y,Zou M,Wang Y,Li Q

更新日期：2015-12-01 00:00:00

abstract：:Abnormal glucose metabolism is critical in colorectal cancer (CRC) development. Expression of the pyruvate kinase (PK) M2 isoform, rather than the PKM1 isoform, serves important functions in reprogramming the glucose metabolism of cancer cells. Preferential expression of PKM2 is primarily driven by alternative splicin...

journal_title：Oncology letters

authors： Sun Y,Luo M,Chang G,Ren W,Wu K,Li X,Shen J,Zhao X,Hu Y

更新日期：2017-12-01 00:00:00

abstract：:Integrin signaling may modulate several different functions involved in cell migration, invasion, proliferation and motility, and is a potential candidate biomarker for oral cancer. In the present study, a total of four integrin genes were evaluated as potential biomarkers of oral squamous cell carcinoma (OSCC). Gene ...

journal_title：Oncology letters

authors： Chang HW,Yen CY,Chen CH,Tsai JH,Tang JY,Chang YT,Kao YH,Wang YY,Yuan SF,Lee SY

更新日期：2018-10-01 00:00:00

abstract：:Ameloblastoma is the most common and clinically relevant type of odontogenic tumor. Clear cell odontogenic carcinoma is histologically characterized by solid sheets and nests of clear cells, whereas clear cell ameloblastoma (CCAM) is histologically characterized by an ameloblastomatous component intermixed with an ext...

journal_title：Oncology letters

authors： Gamoh S,Wato M,Akiyama H,Tsuji K,Ishikawa H,Naruse K,Yoshida H,Morita S,Tanaka A,Shimizutani K

更新日期：2017-12-01 00:00:00

abstract：:The purpose of the present study was to evaluate the newest status of patients diagnosed Burkitt lymphoma (BL), an aggressive lymphoma subset with a high cure rate. Furthermore, the study aimed to create prognostic nomograms to consider various prognostic factors and estimate patient survival, paving the way for clini...

journal_title：Oncology letters

authors： Lu J,Tan H,Li B,Chen S,Xu L,Zou Y

更新日期：2020-01-01 00:00:00

abstract：:Dysregulated expression of long non-coding RNAs has been determined to be important in cancer development; however, their role in tongue squamous cell carcinoma (TSCC) progression and carcinogenesis, to the best of our knowledge, is yet to be elucidated. The present study revealed that long intergenic non-coding RNA 0...

journal_title：Oncology letters

authors： Li X,Rui B,Cao Y,Gong X,Li H

更新日期：2020-03-01 00:00:00

abstract：:Lung cancer is the most common cause of cancer-related mortality in men and women. Non-small cell lung cancer (NSCLC) represents close to 90% of all lung cancers. When diagnosed, >50% of patients are >65 years old. Through an improved understanding of the molecular mechanisms involved in lung oncogenesis, molecular-ta...

journal_title：Oncology letters

authors： Antonelli G,Libra M,Panebianco V,Russo AE,Vitale FV,Colina P,D'Angelo A,Rossello R,Ferraù F

更新日期：2016-01-01 00:00:00

abstract：:Osteosarcoma (OS) is the third most frequent type of cancer in adolescents and represents >56% of all bone tumors. In addition, metastatic OS frequently demonstrates resistance to conventional chemotherapy; thus, the development of novel therapeutic agents for the treatment of patients with metastatic OS is warranted....

journal_title：Oncology letters

authors： Li X,Yan ML,Yu Q

更新日期：2017-06-01 00:00:00

abstract：:Pituitary tumor transforming gene 1 (PTTG11) is abundantly expressed in glioma. Our previous study demonstrated that the downregulation of PTTG11 gene expression significantly inhibited the proliferation, migration and invasion ability, and increased the apoptosis of SHG44 glioma cells. However, the molecular mechanis...

journal_title：Oncology letters

authors： Cui L,Xu L,Wang G,Wen J,Luo L,Zhao H,Chen S,Zheng M,Sun C,Jin X,Yang L

更新日期：2020-10-01 00:00:00

abstract：:Decreased expression of ten-eleven translocation (TET1, TET2 and TET3) proteins has been reported in various types of cancer. However, the expression levels of TET proteins in cervical cancer (CC) remain to be elucidated. The present study determined the levels of TET1, TET2 and TET3 transcripts in cancerous (n=80) an...

journal_title：Oncology letters

authors： Bronowicka-Kłys DE,Roszak A,Pawlik P,Sajdak S,Sowińska A,Jagodziński PP

更新日期：2017-05-01 00:00:00

abstract：:Bladder cancer is one of the most common forms of malignancies involving the urinary system and multiple risk factors have been associated with its etiology. The most common of which include cigarette smoking and various occupational or chemical exposures. It is usually diagnosed in older individuals with an average a...

journal_title：Oncology letters

authors： Khan R,Ibrahim H,Tulpule S,Iroka N

更新日期：2016-05-01 00:00:00