Multiple breath washout quality control in the clinical setting.

abstract：:Nicotine, 1 mg/kg body weight/day, was injected subcutaneously in 3 female rabbits during gestational and lactating periods, and the lungs of the offspring were studied by scanning and transmission electron microscopy (SEM and TEM) on days 5, 10, and 25 postpartum. Three other female rabbits served as controls. The si...

journal_title：Pediatric pulmonology

authors： Chen MF,Diotallevi MJ,Kimizuka G,King M,Wang NS

更新日期：1985-11-01 00:00:00

abstract：:Our objective was to review the clinical features and radiographic manifestations of chest wall lesions in a pediatric chest unit. Twenty-five patients (11 males and 14 females, aged 14 months to 15 years) were suspected of having a chest wall lesion on the basis of clinical examination and chest radiograph. A retrosp...

journal_title：Pediatric pulmonology

authors： Wong KS,Hung IJ,Wang CR,Lien R

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Consolidation on chest radiography is widely used as the reference standard for defining pneumonia and variability in interpretation is well known but not well explored or explained. METHODS:Three pediatric sub-specialists (infectious diseases, radiology and respiratory medicine) viewed 3,033 chest radiogra...

journal_title：Pediatric pulmonology

authors： Williams GJ,Macaskill P,Kerr M,Fitzgerald DA,Isaacs D,Codarini M,McCaskill M,Prelog K,Craig JC

更新日期：2013-12-01 00:00:00

abstract：:We previously demonstrated that infants with a history of bronchopulmonary dysplasia (BPD) exhibit airflow obstruction and air trapping. The purpose of this study was to assess longitudinal changes in pulmonary function in infants with a history of BPD over the first 3 years of life, and the relationship to somatic gr...

journal_title：Pediatric pulmonology

authors： Filbrun AG,Popova AP,Linn MJ,McIntosh NA,Hershenson MB

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Ivacaftor is a significant innovation in the treatment of cystic fibrosis (CF) with gating mutations. A substantial percentage of patients with CF have severe lung involvement, but these patients are usually excluded from phase III clinical trials. Thus, the effectiveness of ivacaftor in this population has ...

journal_title：Pediatric pulmonology

authors： Salvatore D,Carnovale V,Iacotucci P,Braggion C,Castellani C,Cimino G,Colangelo C,Francalanci M,Leonetti G,Lucidi V,Manca A,Vitullo P,Ferrara N

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess pulmonary function and its predictors in very low birth weight (birth weight ≤1,500 g) children (VLBWc) with or without bronchopulmonary dysplasia (BPD), born at gestational age ≤32 weeks at a single tertiary center during 1996-1999, after the introduction of surfactant the...

journal_title：Pediatric pulmonology

authors： Cazzato S,Ridolfi L,Bernardi F,Faldella G,Bertelli L

更新日期：2013-08-01 00:00:00

abstract：:Pulmonary hemangioma is a rare benign tumor of the lungs. Airway hemangiomas in particular may lead to feeding difficulties, barking cough, stridor, respiratory distress, and even acute airway obstruction. Hence, such hemangiomas usually require early and aggressive treatment; however, the treatment modalities employe...

journal_title：Pediatric pulmonology

authors： Emiralioğlu N,Oğuz B,Akyüz C,Yalçın B,Kiper N,Ersöz DD,Yalçın E,Özçelik U

更新日期：2014-08-01 00:00:00

abstract：:There is currently no validated scoring system for quantification of airway secretions in children. A user friendly, valid scoring system of airway secretions during flexible bronchoscopy (FB) would be useful for comparative purposes in clinical medicine and research. The objective of this study was to validate our br...

journal_title：Pediatric pulmonology

authors： Chang AB,Faoagali J,Cox NC,Marchant JM,Dean B,Petsky HL,Masters IB

更新日期：2006-09-01 00:00:00

abstract：:The introduction of NBS in Ireland in July 2011, provided a unique opportunity to investigate clinical outcomes using a comparative historical cohort study. Clinical cohort: children clinically diagnosed with CF born 1 July 2008 to 30 June 2011, and NBS cohort: children diagnosed with CF through NBS born 1 July 2011 t...

journal_title：Pediatric pulmonology

authors： Fitzgerald C,Linnane B,George S,Ni Chroinin M,Mullane D,Herzig M,Greally P,Elnazir B,Healy F,Mc Nally P,Javadpour S,Cox D,Fitzpatrick P

更新日期：2020-09-01 00:00:00

abstract：:The structure, distribution, and frequency of neuroendocrine (NE) cells in human fetal lung from early stages of development to term are described. Neuroendocrine cells were studied by electron microscopy and immunostaining for serotonin and bombesin, recently identified markers of these cells in human lung. The diffe...

journal_title：Pediatric pulmonology

authors： Cutz E,Gillan JE,Bryan AC

更新日期：1985-05-01 00:00:00

abstract：:The purpose of this study was to determine if the interrupter technique, a noninvasive method for measuring airflow resistance, could be used to assess airway obstruction in children. In 107 children (74 with asthma, 12 with cystic fibrosis, and 21 without lung disease) conductance (mostly of airways) measured with th...

journal_title：Pediatric pulmonology

authors： Carter ER,Stecenko AA,Pollock BH,Jaeger MJ

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Childhood wheeze is an important, well-known risk factor for asthma, yet little is known about the contribution of nocturnal dry cough. We investigated the association of nocturnal dry cough at ages 1-7 years with doctor-diagnosed asthma at 8 years of age, both in the presence and absence of wheeze. METHODS...

journal_title：Pediatric pulmonology

authors： Boudewijn IM,Savenije OE,Koppelman GH,Wijga AH,Smit HA,de Jongste JC,Gehring U,Postma DS,Kerkhof M

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:High-frequency (HF) oscillatory ventilation has been shown to improve carbon dioxide (CO2 ) clearance in premature infants. In a previous in vitro lung model with normal lung mechanics we demonstrated significantly improved CO2 washout by HF oscillation of bubble continuous positive airway pressure (BCPAP). ...

journal_title：Pediatric pulmonology

authors： Sivieri EM,Eichenwald EC,Rub D,Abbasi S

更新日期：2020-11-01 00:00:00

abstract：:Tracheoesophageal fistula (TEF) with esophageal atresia (EA) is a common congenital anomaly that is associated with significant respiratory morbidity throughout life. The objective of this document is to provide a framework for the diagnosis and management of the respiratory complications that are associated with the ...

journal_title：Pediatric pulmonology

authors： Koumbourlis AC,Belessis Y,Cataletto M,Cutrera R,DeBoer E,Kazachkov M,Laberge S,Popler J,Porcaro F,Kovesi T

更新日期：2020-10-01 00:00:00

abstract：:Environmental tobacco smoke, also called passive smoking, was shown to have adverse effects on the health of children. Hydrogen peroxide (H2O2) is proposed as a sensitive marker of oxidative injury and inflammatory processes in the airways, being increased in adult active cigarette smokers. We tested whether passive s...

journal_title：Pediatric pulmonology

authors： Doniec Z,Nowak D,Tomalak W,Pisiewicz K,Kurzawa R

更新日期：2005-01-01 00:00:00

abstract：:The gene that encodes for the cystic fibrosis transmembrane regulator protein (CFTR) was identified in 1989, yet major pathophysiologic questions remain unanswered. There is emerging evidence that CFTR is a bicarbonate channel, a driver of chloride-bicarbonate exchange and through its action on local pH, a regulator o...

journal_title：Pediatric pulmonology

authors： Borowitz D

更新日期：2015-10-01 00:00:00

abstract：:We report the case of a 4-year-old child with an atypical presentation of an aspirated unwitnessed foreign body in the airway. During an attempt to obtain a biopsy of what appeared to be a mucosal growth, the foreign body was removed. This may be the first report of foreign body removal in a child this young, using a ...

journal_title：Pediatric pulmonology

authors： Akhter J,Gaspar M,Bassuk A,Roberts J

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVES:The present pilot study was performed to evaluate the HPA axis and ANS activity by measuring salivary cortisol and α-amylase diurnal trajectory and production, respectively, in mild or moderate-to-severe (MS) OSA-affected, but otherwise healthy, children. Moreover, a correlative analysis was performed betwee...

journal_title：Pediatric pulmonology

authors： Patacchioli FR,Tabarrini A,Ghiciuc CM,Dima-Cozma LC,Prete A,Bianchini C,Nicoletti F,Gozal D,Villa MP

更新日期：2014-11-01 00:00:00

abstract：:Obstructive sleep apnea syndrome (OSAS) has been associated with reduced neurocognitive performance in children, but the underlying etiology is unclear. The aim of this study was to evaluate the relationship between hypoxemia, respiratory arousals, and neurocognitive performance in snoring children referred for adenot...

journal_title：Pediatric pulmonology

authors： Kennedy JD,Blunden S,Hirte C,Parsons DW,Martin AJ,Crowe E,Williams D,Pamula Y,Lushington K

更新日期：2004-04-01 00:00:00

abstract：:Aerosolized recombinant human DNase (dornase alfa) reduces mucus viscoelasticity in vitro and improves pulmonary function in patients with cystic fibrosis (CF). We postulated that if dornase alfa could be delivered more peripherally to small airways in the lung in the form of smaller aerosol droplets in patients with ...

journal_title：Pediatric pulmonology

authors： Geller DE,Eigen H,Fiel SB,Clark A,Lamarre AP,Johnson CA,Konstan MW

更新日期：1998-02-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) during early childhood may be associated with subsequent pulmonary sequelae, including recurrent wheezing and asthma. We undertook a systematic review to investigate the pulmonary function sequelae following RSV LRTI in the first 3 years of lif...

journal_title：Pediatric pulmonology

authors： Verwey C,Nunes MC,Dangor Z,Madhi SA

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:To describe the clinical course and treatment of an infant with acute pulmonary toxicity following intralesional administration of bleomycin for a lymphovenous malformation. DESIGN:Case report. SETTING:A tertiary care University-affiliated hospital. PATIENT, INTERVENTION, AND RESULTS:An 8-month-old girl de...

journal_title：Pediatric pulmonology

authors： Atwa K,Abuhasna S,Shihab Z,Hashaykeh N,Hasan R

更新日期：2010-02-01 00:00:00

abstract：:In children unable to perform reliable spirometry, the interrupter resistance (R(int) ) technique for assessing respiratory resistance is easy to perform. However, few data are available on the possibility to use R(int) as a surrogate for spirometry. We aimed at comparing R(int) and spirometry at baseline and after br...

journal_title：Pediatric pulmonology

authors： Beydon N,Mahut B,Maingot L,Guillo H,La Rocca MC,Medjahdi N,Koskas M,Boulé M,Delclaux C

更新日期：2012-10-01 00:00:00

abstract：:Severe bronchopulmonary dysplasia (BPD) is frequently associated with asthma. The combination is often severe enough to necessitate corticosteroid therapy. There are no commercially available nebulizer solutions of corticosteroids for use in infants and young children. Seven infants and small children with very severe...

journal_title：Pediatric pulmonology

authors： König P,Shatley M,Levine C,Mawhinney TP

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Children with adenoid hypertrophy (AH) have impaired respiratory system defense mechanisms, such as mucociliary clearance. We hypothesized that AH negatively affects one of the most important aspects of mucociliary clearance-ciliary beat frequency (CBF) and that adenoidectomy could potentially restore this e...

journal_title：Pediatric pulmonology

authors： Marusiakova L,Durdik P,Jesenak M,Bugova G,Kvassayova J,Oppova D,Banovcin P

更新日期：2020-03-01 00:00:00

abstract：:Eight patients with cystic fibrosis [CF] colonized with Pseudomonas aeruginosa (P. aeruginosa) had serial lung function, peripheral blood inflammatory markers, and serum IgG antibodies to Burkholderia cepacia (B. cepacia) lipopolysaccharide measured in the months preceding and following colonisation with B. cepacia. O...

journal_title：Pediatric pulmonology

authors： Hendry J,Nixon L,Dodd M,Elborn JS,Govan J,Shale DJ,Webb AK

更新日期：2000-01-01 00:00:00

abstract：:Lower respiratory tract infections (LRTI) are common in the first year of life and are mostly caused by viruses. Severity of LRTI in infants is associated with early-life environmental factors. Genetic association studies also suggest a role of heredity in susceptibility to acute bronchiolitis. We designed a case cont...

journal_title：Pediatric pulmonology

authors： Goetghebuer T,Kwiatkowski D,Thomson A,Hull J

更新日期：2004-10-01 00:00:00

abstract：INTRODUCTION:The efficacy of nebulized hypertonic saline (HS) therapy for shortening hospital length of stay (LOS) or improving bronchiolitic symptoms remains controversial. Most studies enrolled small numbers of subjects and did not consider the role of respiratory syncytial virus (RSV), the most common cause of acute...

journal_title：Pediatric pulmonology

authors： Morikawa Y,Miura M,Furuhata MY,Morino S,Omori T,Otsuka M,Chiga M,Obonai T,Hataya H,Kaneko T,Ishikura K,Honda M,Hasegawa Y,Tokyo Pediatric Clinical Research Network.

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:There are few published data on the efficacy of systemic corticosteroids in preterm infants with very severe forms of bronchopulmonary dysplasia (BPD), requiring respiratory support after 3 months of age. The aim of this study was to report the use of pulses of methylprednisolone in this population and its...

journal_title：Pediatric pulmonology

authors： Billion E,Hadchouel A,Garcelon N,Delacourt C,Drummond D

更新日期：2021-01-01 00:00:00

abstract：:Respiratory input impedance (Zin) is a potentially informative test of pulmonary function in infants who are unable to perform standard tests commonly performed in children and adults Analysis of Zin in dogs using the six-element model of DuBois et al. (J Appl Physiol 8:587, 1956) provides estimates of airways resista...

journal_title：Pediatric pulmonology

authors： Jackson AC,Neff KM,Dorkin HL,Lutchen KR

更新日期：1996-12-01 00:00:00