Abstract:
:Karanjin [IUPAC: 3-methoxy-2-phenylfuro-(2,3-h-chrome-4-ol)], a bioactive furanoflavonoid and a potent biomolecule, was first isolated from Pongamia pinnata (L.). The crude extracts from root, leaf and seed having active constituent karanjin is highly valued in both traditional and modern knowledge systems. This review highlights, critically assesses, and presents the probable biosynthetic pathways of karanjin and its isolation methodologies with a view to actualizing its full potential. Karanjin exhibits multiple health benefits and applications, with evident anti-diabetic, anti-cancer, anti-inflammatory, anti-hyperglycemic, antioxidant, anti-colitis, anti-ulcer, and anti-Alzheimer properties. Consequently, the physiochemical properties and biological effects of karanjin have been detailed and analyzed. The efficacy of karanjin has been attenuated by toxicological studies that have proven karanjin to be non-toxic at physiological conditions as substantiated by in vitro and in vivo studies. In addition, the multiple insect repellent/insecticidal properties of karanjin and its availability as an acaricide/bio-insecticide have been reviewed. This review article underscores and endorses the immense potential for novel drug leads in various medicinal and industrial applications, suggesting a deeper insight into its metabolic fate, bioavailability, and cellular effects that await further investigations.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Singh A,Bhatt G,Gujre N,Mitra S,Swaminathan R,Limaye AM,Rangan Ldoi
10.1016/j.phytochem.2020.112641subject
Has Abstractpub_date
2021-01-06 00:00:00pages
112641eissn
0031-9422issn
1873-3700pii
S0031-9422(20)31256-5journal_volume
183pub_type
杂志文章,评审相关文献
PHYTOCHEMISTRY文献大全abstract::The effects of sewage sludges were investigated on the symbiotic interactions between the model plant Medicago truncatula and the arbuscular mycorrhizal fungus Glomus mosseae or the rhizobial bacteria Sinorhizobium meliloti. By comparison to a control sludge showing positive effects on plant growth and root symbioses,...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2004.04.037
更新日期:2004-06-01 00:00:00
abstract::The secondary metabolite contents and genetic profiles of six Hypericum species (H. barbatum Jacq., H. hirsutum L., H. linarioides Bosse, H. maculatum Crantz, H. rumeliacum Boiss. and H. tetrapterum Fries), collected from different locations in Serbia, have been analyzed. Methanol extracts of the aerial parts of the p...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2005.10.021
更新日期:2006-01-01 00:00:00
abstract::Four coumaronochromones, formosanatins A-D (-4), and a flavanone, euchrenone a(16), along with four known compounds, euchretins E and G, euchrestaflavanone A, and daidzein, were isolated from the roots of Euchresta formosana. The structures of - were established by spectroscopic analyses. ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/s0031-9422(02)00017-1
更新日期:2002-08-01 00:00:00
abstract::Two new furostanol saponins, named chinenosides II and III, were isolated along with seven known compounds, from the bulbs of Allium chinese G. Don by a combination of silica gel, Diaion HP-20, and octadecylsilanized (ODS) silica gel column chromatographies and preparative HPLC. On the basis of chemical and spectrosco...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/0031-9422(95)00553-6
更新日期:1996-01-01 00:00:00
abstract::Nine new bidesmosidic 3-O-glucuronide oleanane triterpenoid saponins were isolated from the stem bark of Symplocos glomerata King along with two known saponins, salsoloside C and copteroside E, and two major lignans, (-)-pinoresinol and (-)-pinoresinol-4'-O-beta-D-glucopyranoside. The structures of the new saponins we...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2004.01.012
更新日期:2004-03-01 00:00:00
abstract::Two new ent-labdane glycosides, one known furano-ent-labdane and a new hydroxylated fatty acid were isolated from the dichloromethane extract of the freshwater aquatic plant Potamogeton lucens. The new compounds were assigned the structures of beta-d-glucopyranosyl-8(17),13-ent-labdadien-16,15-olid-18-oate, 18-beta-d-...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2004.01.018
更新日期:2004-04-01 00:00:00
abstract::Examination of the bulbs of Bessera elegans (Liliaceae) led to isolation of nine new and five known steroidal glycosides. The structures of the nine compounds were determined based on the results of spectroscopic analysis, including two-dimensional NMR, and hydrolysis followed by chromatographic and spectroscopic anal...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2013.09.023
更新日期:2013-12-01 00:00:00
abstract::The structure of four diterpenoid glucosides, designated as salvigresides A-D (1-4), isolated from the aerial parts of Salvia greggii, have been confirmed by spectroscopic and chemical investigation. ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2004.08.012
更新日期:2004-09-01 00:00:00
abstract::From the MeOH extract of the leaves of W. japonica, seven phenylpropanoid gentiobiosides (1-7) were isolated along with eight known phenylpropanoids (8-15). Structures of 1-7 were determined based on spectroscopic data and chemical evidence. The activity of compounds 1-15 to scavenge superoxide anion radicals was inve...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2007.08.021
更新日期:2008-02-01 00:00:00
abstract::The fatty acid compositions of 22 species of marine macrophytes, belonging to the Ceramiales, Cryptonemiales, Nemalionales, Laminariales, Chordariales, Scytosiphonales, Desmarestiales, Dictyosiphonales, Fucales, Dictyotales and Ulvales and collected from the Bohai Sea, were determined by capillary gas chromatography. ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/s0031-9422(01)00437-x
更新日期:2002-01-01 00:00:00
abstract::Cinnamyl alcohol dehydrogenase (CAD) (EC 1.1.1.195) from a dicot, Aralia cordata, was purified to homogeneity and its properties were characterized. The enzyme shows a preference for cinnamyl alcohols and cinnamyl aldehydes as substrates. The M(r) is estimated at 72,000. The enzyme is composed of two heterogeneous sub...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/s0031-9422(00)95137-9
更新日期:1993-02-01 00:00:00
abstract::The role and fate of Jasmonoyl-Phenylalanine (JA-Phe), an understudied conjugate in the jasmonate pathway remain to be unraveled. We addressed here the possibility of JA-Phe oxidative turnover by cytochrome P450s of the CYP94 family. Leaf wounding or fungal infection in Arabidopsis resulted in accumulation of JA-Phe, ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2015.06.027
更新日期:2015-09-01 00:00:00
abstract::Three undescribed aporphine alkaloids laurodionine B (1), illigerine A (2), and N-formyl-laurolitsine (3) were isolated from the methanolic extracts of the Chinese medicinal plant, Illigera aromatica, together with three known analogues (4-6). The chemical structures of 1-6 were identified by spectroscopic methods inc...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2018.06.017
更新日期:2018-10-01 00:00:00
abstract::Crotaoprostrin, a chalcone not yet known as a plant constituent, was isolated from the aerial parts of the Indian medicinal plant Crotalaria prostrata. The structures of the chalcone polyarvin and the partially hydrogenated naturally occurring derivatives crotaramin, crotaramosmin, and crotin were confirmed by chemica...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/s0031-9422(02)00475-2
更新日期:2002-12-01 00:00:00
abstract::The effects of exogenous silicon (Si) on plant growth, activities of superoxide dismutase (SOD), guaiacol peroxidase (GPX), ascorbate peroxidase (APX), dehydroascorbate reductase (DHAR), glutathione reductase (GR) and catalase, and concentrations of ascorbate and glutathione were investigated in cucumber (Cucumis sati...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2005.05.006
更新日期:2005-07-01 00:00:00
abstract::Eight previously undescribed ditepenoids, including four oxygenated abietanes (roscotanes A-D) and four oxygenated pimaranes (roscoranes A-D), along with twelve known diterpenoids were isolated from the whole plants of Kaempferia roscoeana. Their structures were elucidated by extensive spectroscopic analysis, and the ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2017.07.008
更新日期:2017-11-01 00:00:00
abstract::Silene species are known for their use in traditional medicine in treating several diseases. To the authors' knowledge there is no report on the chemical composition of S. odontopetala. Therefore, the phytochemical investigation of the methanol extract of S. odontopetala was carried out, leading to the isolation of si...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2020.112404
更新日期:2020-08-01 00:00:00
abstract::The incomplete structure proposed in 1972 for a unique "flavone-polysaccharide" compound, MF-1, from the liverwort Monoclea forsteri, has been re-examined. Rather than the proposed 8-methoxyluteolin structure with polysaccharides attached to the 7- and 4'-hydroxyls, MF-1 has been shown to be primarily a mixture of pen...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/s0031-9422(03)00199-7
更新日期:2003-07-01 00:00:00
abstract::Leaves, stem bark and root of Lonchocarpus xuul and Lonchocarpus yucatanensis were studied separately. A chalcone, 2',4-dimethoxy-6'-hydroxylonchocarpin (), and the flavones 5,4'-dihydroxy-3'-methoxy-(6:7)-2,2-dimethylpyranoflavone (2) and 5,4'-dimethoxy-(6:7)-2,2-dimethylpyrano-flavone (3), together with the known ca...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/s0031-9422(02)00131-0
更新日期:2002-07-01 00:00:00
abstract::The patterns of secondary metabolites in leaves of yeast invertase-transgenic tobacco plants (Nicotiana tabacum L. cv. Samsun NN) were analyzed. Plants expressing cytosolic yeast-derived invertase (cytInv) or apoplastic (cell wall associated) yeast invertase (cwInv) showed a characteristic phytochemical phenotype comp...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/s0031-9422(00)00422-2
更新日期:2001-03-01 00:00:00
abstract::The rare series of (4-->5)-linked proteracacinidins is extended by identification of oritin-(4alpha-->5)-epioritin-4beta-ol, ent-epioritin-(4alpha-->5)-epioritin-4beta-ol, epioritin-(4beta-->5)-epioritin-4alpha-ol and ent-oritin-(4beta-->5)-epioritin-4alpha-ol from the heartwoods of Acacia galpinii and Acacia caffra. ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/s0031-9422(02)00010-9
更新日期:2002-03-01 00:00:00
abstract::Phytochemical investigation of the flowers of Inula japonica led to isolation of nine sesquiterpenoids, inujaponins A-I, as well as eighteen known ones. These sesquiterpenoids belong to six skeletal-types, including eudesmane, 1,10-seco-eudesmane, germacrane, guaiane, 4,5-seco-guaiane, and pseudoguaiane sesquiterpenoi...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2016.07.008
更新日期:2016-09-01 00:00:00
abstract::Poliumoside, forsythoside B, echinacoside and arenarioside, caffeic glycoside esters, were isolated from several species of Oleaceae. The poliumoside/forsythoside ratio distinguishes Jasminum nudiflorum from J. mesnyi. Arenarioside and forsythoside B act in Forsythia species as good hybridization markers. ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/0031-9422(92)80032-a
更新日期:1992-03-01 00:00:00
abstract::Chemical investigation of the glandular trichome exudate from Silene gallica L. (Caryophyllaceae) resulted in isolation of 10 cyclic fatty acyl glycosides (gallicasides A-J). The cyclic structures were characterized by a glycosidic linkage of the glucose moiety to either the C-12 or the C-13 position of the octadecano...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2010.05.008
更新日期:2010-08-01 00:00:00
abstract::Five labdane diterpenoids, (3-5), zambesiacolactone A (7) and zambesiacolactone B (8), were isolated from the seeds of Aframomum zambesiacum (Baker) K. Schum., along with five known labdanes and a linear sesquiterpene, nerolidol. Their structures were elucidated by spectroscopic analysis. Their antiplasmodial activity...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2005.10.015
更新日期:2006-03-01 00:00:00
abstract::Haplophyllum buxbaumii has yielded a new diphyllin glycoside, which was characterized as 4-O-{bis-alpha-L-xylopyranosyl (1-->2, 1-->5) beta-D-apiofuranosyloxy}-6,7-dimethoxy-1-(3,4-methylenedioxyphenyl)-3-hydroxymethyl naphthalene-2-carboxylic acid lactone. Taiwanin-H is also reported for the first time from a member ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/s0031-9422(98)00222-2
更新日期:1998-11-20 00:00:00
abstract::Carrageenans extracted from gametophytic and sporophytic Chondrus crispus were analysed by hydrolysis, KCl fractionation and 1H NMR spectroscopy. The carrageenan from gametophytic plants is composed predominantly of two KCl insoluble fractions which contain kappa-carrageenan as the major component with 1-carrageenan a...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/0031-9422(92)90032-l
更新日期:1992-02-01 00:00:00
abstract::Non-targeted LC-MS metabolomics on fruit of three wild and domesticated apple species (Malus sylvestris, M. sieversii and M. domestica) showed that two crab apple (M. sylvestris) accessions were distinguished by high concentrations of an ascorbic acid glycoside (AAG). This was partly purified, but key NMR signals were...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2020.112297
更新日期:2020-05-01 00:00:00
abstract::A new highly oxygenated triterpene named ganoderic acid alpha has been isolated from a methanol extract of the fruiting bodies of Ganoderma lucidum together with twelve known compounds. The structures of the isolated compounds were determined by spectroscopic means including 2D-NMR. Ganoderiol F and ganodermanontriol ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/s0031-9422(98)00254-4
更新日期:1998-11-01 00:00:00
abstract::Plants have developed a plethora of signals to interact with other organisms, finally building up a sophisticate language for communication. In this context, we investigated Salvia verticillata L. (Lamiaceae), with the primary goal to link secondary metabolites and actual biotic relationships. We specifically analysed...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2018.07.016
更新日期:2018-11-01 00:00:00