Abstract:
:Research into the mechanisms regulating bacterial cell size has its origins in a single paper published over 50 years ago. In it Schaechter and colleagues made the observation that the chemical composition and size of a bacterial cell is a function of growth rate, independent of the medium used to achieve that growth rate, a finding that is colloquially referred to as 'the growth law'. Recent findings hint at unforeseen complexity in the growth law, and suggest that nutrients rather than growth rate are the primary arbiter of size. The emerging picture suggests that size is a complex, multifactorial phenomenon mediated through the varied impacts of central carbon metabolism on cell cycle progression and biosynthetic capacity.
journal_name
Curr Opin Microbioljournal_title
Current opinion in microbiologyauthors
Vadia S,Levin PAdoi
10.1016/j.mib.2015.01.011subject
Has Abstractpub_date
2015-04-01 00:00:00pages
96-103eissn
1369-5274issn
1879-0364pii
S1369-5274(15)00012-0journal_volume
24pub_type
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