Abstract：
:Clinicians are less likely to recommend adjuvant chemotherapy for older adults based on their age alone. This study aimed to develop a mortality risk model to assist treatment decision making by identifying patients who are unlikely to live to benefit from chemotherapy. All lymph node-positive colon cancer patients ≥65 years who received surgery in New South Wales, Australia in 2007/2008 were identified using a linked population-based dataset (n = 1550). A model predicting 1-year all-cause mortality was built using multilevel logistic regression. Risk scores derived from model factors were summed for each patient. One-year mortality was 11.5%. The risk model consisted of 14 factors, including comorbidities, hospital admission factors and other markers of frailty or health status. People with a total score of 0, 1 or 2 were considered at low risk (predicted 1-year mortality of 2.9%), those scoring 3 to 8 at medium risk (7.4% mortality) and those scoring 9 or above at high risk (24.7% mortality). The model had good discrimination (area under the receiver operating characteristic curve = 0.788, 95% confidence interval: 0.752-0.825) and calibration (P = 0.46). The risk model accurately predicts mortality for this cohort and could be useful in shifting the emphasis in chemotherapy decision making from chronological age to the identification of those of any age who will benefit.
journal_name
Eur J Cancer Care (Engl)journal_title
European journal of cancer careauthors
Jorgensen ML,Young JM,Dobbins TA,Solomon MJdoi
10.1111/ecc.12288subject
Has Abstractpub_date
2015-03-01 00:00:00pages
179-88issue
2eissn
0961-5423issn
1365-2354journal_volume
24pub_type
杂志文章abstract：OBJECTIVE:Documentations of the experiences of patients with advanced prostate cancer and their partners are sparse. Views of care and treatment received for metastatic castrate-resistant prostate cancer (mCRPC) are presented here. METHODS:Structured interviews conducted within 14 days of a systemic therapy for mCRPC ...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.13140
更新日期：2019-11-01 00:00:00
abstract：:In order to improve outcomes, identification of the epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) genes has become crucial in advanced non-small-cell lung cancer (NSCLC). The aim of the present study is to analyse time trends and frequency of testing, factors affecting testing as well as...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12721
更新日期：2017-11-01 00:00:00
abstract：:Female partners of prostate cancer (PCa) survivors experience heightened psychological distress that may be greater than that expressed by PCa patients. However, optimal approaches to detect distressed, or at risk of distress, partners are unclear. This study applied receiver operating characteristics analysis to eval...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12924
更新日期：2019-01-01 00:00:00
abstract：:This systematic review and meta-analysis aimed to evaluate the effectiveness of psychological interventions in improving quality of life for head and neck cancer patients. Five databases were systematically searched in July 2016. Studies were included if they reported original empirical data from intervention studies ...
journal_title：European journal of cancer care
pub_type： 杂志文章,meta分析,评审
doi：10.1111/ecc.12789
更新日期：2018-01-01 00:00:00
abstract：:The purpose of this study was to examine the effect of a whole body exercise programme and dragon boat training on changes in arm volume in breast cancer survivors. A total of 16 female breast cancer survivors with no clinical history of lymphoedema volunteered. The 20-week exercise programme consisted of resistance a...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2005.00595.x
更新日期：2005-09-01 00:00:00
abstract：:Mirtazapine and olanzapine are easy-to-use psychiatric drugs with potent antinausea effects. Ondansetron and later members of the 'setron class are currently standard treatments for cancer chemotherapy-related nausea and emesis. They are potent 5-HT3 blockers, but it is often not appreciated that mirtazapine and olanz...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2006.00760.x
更新日期：2007-07-01 00:00:00
abstract：:Open learning is increasing in importance in nurse education. In this article the author considers open learning and discusses its use in palliative care education. Advantages and disadvantages of this learning method are considered and guidelines are offered to the teacher to assist them to evaluate existing learning...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.1994.tb00028.x
更新日期：1994-09-01 00:00:00
abstract：:This study was undertaken to gain insight in the views and experiences of oncology healthcare providers in Flanders, the Dutch-speaking part of Belgium, on caring for patients of non-Western descent. A qualitative research design with the constant comparative method was used. Data were collected through five focus gro...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12481
更新日期：2017-11-01 00:00:00
abstract：:The study aimed to evaluate cancer-targeting potential of a newly synthesised radiopharmaceutical, 99m Tc-resveratrol in vivo, using colon cancer model. Colon cancer was induced in 20 male Sprague-Dawley rats by subcutaneous administration of 1,2-dimethylhydrazine (DMH), dissolved in 1 mM EDTA-normal saline, at a dose...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12504
更新日期：2017-09-01 00:00:00
abstract：:Head and Neck (H&N) cancer treatment can have a major detrimental impact on patient lives, and these issues can go unrecognised and be inadequately addressed. The aim of this paper is to compare the Patient Concerns Inventory (PCI) responses across age groups attending routine H&N cancer follow-up clinics with particu...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12289
更新日期：2015-03-01 00:00:00
abstract：:This study was conducted to explore the interrelationships among caregiver burden, emotional status and quality of life (QoL) in caregivers of lung cancer patients, and to identify whether caregiver burden and health status are associated with patient emotional status and QoL. Forty-three dyads of lung cancer patients...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12691
更新日期：2018-01-01 00:00:00
abstract：:A moisturising micro-gel spray for prevention of dryness was compared with commercial products and artificial saliva in vitro and in a clinical setting in patients with cancer. Survival of cultured human gingival epithelial cells was evaluated after treatment with each product for 15 min. A dry test was performed for ...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2012.01349.x
更新日期：2012-11-01 00:00:00
abstract：:Fluconazole is recommended in the prophylaxis of oropharyngeal candidiasis (OPC) in patients undergoing radiotherapy for head-neck tumours; however, the actual effectiveness of fluconazole in this setting remains unclear. Adult patients with cervico-cephalic carcinoma submitted to radical or adjuvant radiotherapy were...
journal_title：European journal of cancer care
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1365-2354.2007.00855.x
更新日期：2008-05-01 00:00:00
abstract：:This narrative review of the literature examines the issues influencing chemotherapy treatment of older patients with cancer. Increasing age is associated with physical, social and psychological changes, but the rate of change differs widely between people, such that chronological age is not a good determinant of fitn...
journal_title：European journal of cancer care
pub_type： 杂志文章,评审
doi：10.1111/j.1365-2354.2011.01294.x
更新日期：2012-01-01 00:00:00
abstract：:The aim of this study was to describe family members' life situation and experiences of care in two different care settings, the patient's home or in hospital during the acute post-transplantation phase after allogeneic haematopoietic stem cell transplantation (HSCT). Data were collected through semi-structured interv...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12610
更新日期：2018-01-01 00:00:00
abstract：:Psychological factors, including distress and fears of recurrence, may be implicated in explaining why head and neck oncology patients continue or refrain from smoking. The aim was to determine the role of psychological factors in understanding smoking behaviour in a consecutive group of cancer patients attending a Re...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2004.00479.x
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVE:Gastroesophageal cancer has high mortality, and continuous assessment of patient-reported data is salient for optimisation of supportive care. We aimed to evaluate our multidisciplinary concept with respect to patient-reported variables. METHODS:At diagnosis and later during the treatment, three areas of pat...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.13200
更新日期：2020-03-01 00:00:00
abstract：:Adverse events (AEs) of epidermal growth factor inhibitors (EGFRi) influence well-being with a risk to dose modifications (DMs). Hereby, clinical benefit of treatment might be affected. This retrospective cohort study was set up to gain insight into the suitability and added value of a patient-reported outcome measure...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12800
更新日期：2018-03-01 00:00:00
abstract：:This study explored men's experiences of transrectal prostate biopsy. Fifty men who had had a prostate biopsy talked about the experience as part of an in-depth interview; 36 were interviewed in 2000 about all aspects of prostate cancer, and 14 in 2005 about their experience of prostate-specific antigen testing, subse...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2006.00766.x
更新日期：2007-05-01 00:00:00
abstract：OBJECTIVE:Surgery for paediatric cancer presents many stresses on patients and families. The authors aimed to understand the long-term impact of childhood cancer surgery on survivors and parents. METHODS:The study recruited participants from 11 Australia/New Zealand hospitals for telephone interviews. The authors used...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.13116
更新日期：2019-09-01 00:00:00
abstract：:Close monitoring of chemotherapy toxicity can be instrumental in ensuring prompt symptom management and quality care. Our aim was to develop a brief clinical tool to enable daily assessment of chemotherapy toxicity and investigate/establish its content validity, feasibility/applicability, internal consistency and stab...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12890
更新日期：2018-11-01 00:00:00
abstract：:Although several studies have reported the impact of oesophagectomy on health-related quality of life (HRQOL), none has objectively assessed its impact on physical fitness. This study aimed to evaluate the impact of oesophagectomy on physical fitness and HRQOL in patients with oesophageal cancer. In this prospective s...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12030
更新日期：2013-05-01 00:00:00
abstract：:It is estimated that 20-25% of cancer patients suffer often unrecognized and untreated long-term depression, a condition that can make life miserable. Symptoms can include: lack of sleep; loss of interest in life; anxiety; irritation; loss of concentration; and, in severe cases, thoughts of suicide; leading to an over...
journal_title：European journal of cancer care
pub_type： 杂志文章,评审
doi：10.1046/j.1365-2354.1998.00100.x
更新日期：1998-09-01 00:00:00
abstract：:The aim of the present study was to evaluate quality of life (QoL) parameters in patients with metastatic breast cancer (MBC) and assess the potential differences between patients receiving chemotherapy and those undergoing supportive care interventions. In total, 210 women with MBC were enrolled in this prospective, ...
journal_title：European journal of cancer care
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1365-2354.2006.00771.x
更新日期：2007-09-01 00:00:00
abstract：:Sarcomas often occur in patients' extremities and treatment typically involves bone resection/limb salvage surgery. Such treatments leave survivors with physical disfigurements, functional disabilities, and/or emotional traumas. Our post-surgery psychological intervention investigated how these experiences impinge on ...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12667
更新日期：2017-11-01 00:00:00
abstract：:A project was funded by the UK's Department of Health to develop national guidelines for breast cancer related lymphoedema using a Consensus Strategy. This involved the organization of a consensus conference with a multidisciplinary panel of experts, an extensive literature review, the production of clinical guideline...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.1996.tb00243.x
更新日期：1996-12-01 00:00:00
abstract：:Based on promising preclinical data, a progressive series of evaluations of the use of high-dose mitoxantrone-based chemotherapy was initiated in acute leukaemia patients. A preliminary phase I study demonstrated that up to 80 mg/m2 of mitoxantrone in combination with cytarabine 3 g/m2 daily for 5 days could be given ...
journal_title：European journal of cancer care
pub_type： 临床试验,杂志文章,随机对照试验,评审
doi：10.1111/j.1365-2354.1997.tb00322.x
更新日期：1997-12-01 00:00:00
abstract：INTRODUCTION:Mastectomy patients' satisfaction with reconstructive options has not been examined. METHODS:A national study measured 18-month satisfaction with reconstructive options and collected case-mix and reconstructive offer and uptake data on breast cancer patients having mastectomy with or without immediate rec...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.13362
更新日期：2020-11-10 00:00:00
abstract：:Previous research has reported that patients require specific information relating to radiotherapy; however, these studies fail to describe patients' specific information needs over time. The aims of this study were to determine the specific information needs of breast cancer patients who are receiving radiotherapy an...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2009.01090.x
更新日期：2010-07-01 00:00:00
abstract：:The aim was to explore what expectations patients have concerning the recovery period after completed curative cancer treatment and the degree to which these expectations were realized slightly more than 1 year later. A purposeful sample of 16 patients was selected from a larger study and those patients were interview...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2008.00933.x
更新日期：2009-11-01 00:00:00
