Abstract:
:This narrative review of the literature examines the issues influencing chemotherapy treatment of older patients with cancer. Increasing age is associated with physical, social and psychological changes, but the rate of change differs widely between people, such that chronological age is not a good determinant of fitness for treatment. Changes in old age can affect disease processes and treatments that are offered. Clinical trials suggest that older patients gain benefits from chemotherapy, but with increased toxicity profile. Dose reductions may be required, but the effect on outcome is not known. Adjuvant chemotherapy is likely to benefit patients with a life expectancy over 5 years, although mortality benefits become less pronounced with increasing age. Older patients want chemotherapy, as long as side effects do not reduce quality of life or ability to function independently. Older patients face barriers to communication with professionals, including sensory and memory problems and poorer health literacy. Patients should be assessed covering functional, physiological and socio-economic domains that identify significant comorbid disease and frailty, to ensure that planned chemotherapy is appropriate. Successful treatment of older patients with chemotherapy may require interventions to support them to ensure all patients who may derive benefit can undergo treatment, if they so wish.
journal_name
Eur J Cancer Care (Engl)journal_title
European journal of cancer careauthors
Johnson Mdoi
10.1111/j.1365-2354.2011.01294.xsubject
Has Abstractpub_date
2012-01-01 00:00:00pages
3-9issue
1eissn
0961-5423issn
1365-2354journal_volume
21pub_type
杂志文章,评审abstract::For blood cancer patients, haematopoietic stem cells (HSC) donated by a relative can be lifesaving. However, related donors can face significant physical and psychosocial challenges. As the demand for adult-related HSC donors is increasing, it is important to review our understanding of adult-related HSC donors' need ...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12932
更新日期:2019-05-01 00:00:00
abstract::This study aimed to examine the sensory descriptors used by women undergoing their first ever colposcopy examination as part of cervical cancer screening. Immediately following colposcopy, women were asked to provide detailed information about the sensory, affective, evaluative and intensity properties of the colposco...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12343
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Prehabilitation is increasingly being used to mitigate treatment-related complications and enhance recovery. An individual's state of health at diagnosis, including obesity, physical fitness and comorbidities, are influencing factors for the occurrence of adverse effects. This review explores whether prehabil...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.13023
更新日期:2019-07-01 00:00:00
abstract::This study aimed to identify high support needs and their socio-demographic predictors to improve supportive care for newly diagnosed breast cancer patients. A cross-sectional study measured patients' needs and unsatisfied support needs by the supportive care needs survey (SCNS-34), administered after surgery, chemoth...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2010.01190.x
更新日期:2011-07-01 00:00:00
abstract::This paper compares quality of life in breast and rectal cancer patients. The Munich Cancer Registry records clinical details of all cancer patients in the region. Over a 2-year period, cooperating clinicians recruited patients who were sent quality of life questionnaires, including the European Organization for Resea...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1046/j.1365-2354.2003.00414.x
更新日期:2003-09-01 00:00:00
abstract::The aim of this study was to conduct a systematic review of the literature on the needs of adolescents and young adults (AYAs) who have survived cancer. PRISMA recommendations for systematic reviews were followed, and the quality of the studies reviewed was also assessed with a specific checklist. The following databa...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12558
更新日期:2018-11-01 00:00:00
abstract::The aim of this study was to describe the information and support needs of women who have primary relatives with breast cancer. The Information and Support Needs Questionnaire (ISNQ) was developed and revised from previous qualitative and pilot studies. The ISNQ addressed concepts of the importance of, and the degree ...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1046/j.1365-2354.2003.00330.x
更新日期:2003-03-01 00:00:00
abstract::Cancer-related pain (CRP) is common and many patients continue to experience pain in spite of advances in pain management modalities. The lack of knowledge, inadequate assessment of CRP and/or organisational factors, such as lack of time due to heavy workload, can be a barrier to effective pain management of healthcar...
journal_title:European journal of cancer care
pub_type: 杂志文章,评审
doi:10.1111/ecc.12625
更新日期:2017-11-01 00:00:00
abstract::This systematic review and meta-analysis aimed to evaluate the effectiveness of psychological interventions in improving quality of life for head and neck cancer patients. Five databases were systematically searched in July 2016. Studies were included if they reported original empirical data from intervention studies ...
journal_title:European journal of cancer care
pub_type: 杂志文章,meta分析,评审
doi:10.1111/ecc.12789
更新日期:2018-01-01 00:00:00
abstract::While colorectal cancer is the most common cancer affecting both men and women in Australia, disease-specific peer support services are lacking. This study examined the acceptability and preferred models of peer support among people with colorectal cancer. First, a mixed-method study examined enablers and barriers to ...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2010.01218.x
更新日期:2011-07-01 00:00:00
abstract::Cancer is difficult for people from ethnically diverse communities to cope with, because there is inequality in getting information and services to meet their needs for prevention, prompt diagnosis, treatment, care and support. Research with black minority ethnic (BME) communities indicates a lack of knowledge about c...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2006.00719.x
更新日期:2007-03-01 00:00:00
abstract::A moisturising micro-gel spray for prevention of dryness was compared with commercial products and artificial saliva in vitro and in a clinical setting in patients with cancer. Survival of cultured human gingival epithelial cells was evaluated after treatment with each product for 15 min. A dry test was performed for ...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2012.01349.x
更新日期:2012-11-01 00:00:00
abstract::To investigate health professionals' perspectives about factors that impede or facilitate cancer care for Indigenous people. Semi-structured interviews with 22 health professionals involved in Indigenous cancer care. Data were interpreted using an inductive thematic analysis approach. Participants presented their pers...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12467
更新日期:2016-03-01 00:00:00
abstract::Although several studies have reported the impact of oesophagectomy on health-related quality of life (HRQOL), none has objectively assessed its impact on physical fitness. This study aimed to evaluate the impact of oesophagectomy on physical fitness and HRQOL in patients with oesophageal cancer. In this prospective s...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12030
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:Fear of cancer recurrence (FCR) is the most commonly reported problem and unmet need among breast cancer survivors. The aim of this qualitative study was to explore the experience of recurrence fears among Taiwanese breast cancer survivors. METHODS:Three focus groups were included in this study. A purposive ...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.13113
更新日期:2019-09-01 00:00:00
abstract::No instrument is available to assess the impact of faecal incontinence (FI) of quality of life for Chinese-speaking population. The purpose of the study was to adapt the Faecal Incontinence Quality of Life Scale (FIQL) for patients with colorectal cancer, assess the factor structure and reduce the items for brevity. A...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12547
更新日期:2017-09-01 00:00:00
abstract::The concept of clinical supervision has received considerable attention in the nursing literature of late, enjoying favour not only with many practitioners and managers, but academics and policy makers alike. The following paper considers the utility of clinical supervision within the cancer nursing setting, concentra...
journal_title:European journal of cancer care
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2354.1996.tb00205.x
更新日期:1996-03-01 00:00:00
abstract::Based on promising preclinical data, a progressive series of evaluations of the use of high-dose mitoxantrone-based chemotherapy was initiated in acute leukaemia patients. A preliminary phase I study demonstrated that up to 80 mg/m2 of mitoxantrone in combination with cytarabine 3 g/m2 daily for 5 days could be given ...
journal_title:European journal of cancer care
pub_type: 临床试验,杂志文章,随机对照试验,评审
doi:10.1111/j.1365-2354.1997.tb00322.x
更新日期:1997-12-01 00:00:00
abstract::Informational need assessment has become an important part of health care in order to provide information effectively in clinical settings. Literature on information needs in the West suggests that breast cancer (BC) patients needed more information than doctors had provided, and information that fully met their needs...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2008.00936.x
更新日期:2009-03-01 00:00:00
abstract::Lack of understanding or knowledge of research among patients participating in randomized clinical trials (RCTs) is common. However, there is a lack of validated measures to assess the extent of the problem. The aim of this study was to develop and pilot a questionnaire to assess knowledge and understanding of RCTs in...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2006.00732.x
更新日期:2007-03-01 00:00:00
abstract::Previous reports on the patient perspective of daily life during a 1-year high-grade glioma (HGG) trajectory from the time of diagnosis are sparse. The aim of this longitudinal mixed methods study is to identify the specific needs and preferences for rehabilitation and supportive care and how it links with physical ac...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12806
更新日期:2018-03-01 00:00:00
abstract::Head and Neck (H&N) cancer treatment can have a major detrimental impact on patient lives, and these issues can go unrecognised and be inadequately addressed. The aim of this paper is to compare the Patient Concerns Inventory (PCI) responses across age groups attending routine H&N cancer follow-up clinics with particu...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12289
更新日期:2015-03-01 00:00:00
abstract::During 2008-2009, only 4% of women targeted for cervical screening were screened in Tshwane, South Africa. The purpose of the study was to determine whether cervical screening uptake could be improved when breast and cervical screening are combined. An intervention research design was used. The intervention was assess...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2011.01292.x
更新日期:2012-01-01 00:00:00
abstract::Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a benign self-limiting disorder of unknown aetiology, which is frequently mistaken for lymphoma. There is no consensus as to the proper management of this disorder. In the past, potentially harmful treatments, such as antin...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2006.00746.x
更新日期:2007-05-01 00:00:00
abstract::Patients with lung cancer who undergo surgery may potentially be cured. The resulting pathological staging gives an indication of 5-year survival and whether further treatment is recommended. To date, there is little research evidence regarding the way potential recurrence is communicated to patients by staff. This qu...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12870
更新日期:2018-09-01 00:00:00
abstract::The fear of cancer recurrence is cited as a motivator of women's preferences between routine monitoring and contralateral prophylactic mastectomy (CPM) as methods of managing ongoing breast cancer risk. We conducted a discrete choice experiment among a general community sample of women who completed 12 hypothetical ch...
journal_title:European journal of cancer care
pub_type: 杂志文章,随机对照试验
doi:10.1111/ecc.13058
更新日期:2019-07-01 00:00:00
abstract::The aim of this pilot study was to assess the effectiveness of using progressive muscle relaxation training (PMRT) in the management of chemotherapy-related nausea and vomiting in Chinese breast cancer patients receiving doxorubicin and cyclophosphamide as well as feasibility issues for a larger study. Eight patients ...
journal_title:European journal of cancer care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2354.2000.00220.x
更新日期:2000-12-01 00:00:00
abstract::As part of a major study of the impact of childhood cancer on Chinese families, 17 families agreed to be interviewed after the death of their child from cancer. They convey what happens to the child's body after death and what remembrances the family has kept of their child's belongings. They share how they have adjus...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.1993.tb00192.x
更新日期:1993-12-01 00:00:00
abstract::The aim of the study was to investigate the management and outcome of inguinal recurrence in vulvar carcinoma patients. A retrospective chart review was conducted on 140 patients with squamous cell carcinoma of the vulva treated between 1994 and 2006. Twenty-one patients were found to have groin recurrence. Median int...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2008.01011.x
更新日期:2010-05-01 00:00:00
abstract::The purpose of this study is to document infection and to better understand current practice relating to antibiotic use and its effect in terminal cancer patients. We retrospectively reviewed patients with terminal stage cancer who were admitted to Seoul National University Boramae Hospital for symptom control only, a...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2005.00603.x
更新日期:2006-03-01 00:00:00