Abstract:
:A double-blind study was undertaken to determine the effects of megadose ascorbic acid supplementation on plasma ascorbate levels, polymorphonuclear neutrophil (PMN) chemotaxis and clinical and biochemical determinations of inflammatory progression in individuals with a mean daily ascorbate intake level of approximately twice the recommended daily allowances. Results indicate that although the group receiving ascorbate supplementation demonstrated a significant increase in plasma levels of the vitamin as compared to a placebo group, no significant differences with respect to PMN chemotaxis or responses to experimental gingivitis were found between the groups.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Vogel RI,Lamster IB,Wechsler SA,Macedo B,Hartley LJ,Macedo JAdoi
10.1902/jop.1986.57.8.472subject
Has Abstractpub_date
1986-08-01 00:00:00pages
472-9issue
8eissn
0022-3492issn
1943-3670journal_volume
57pub_type
临床试验,杂志文章abstract:BACKGROUND:Generalized aggressive periodontitis is described as a clinical entity affecting both deciduous and permanent dentition with extensive alveolar bone loss, mobility, and exfoliation of all or many teeth. Controversy exists on dental implant use to restore missing dentition in younger patients. METHODS:This c...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2001.72.3.411
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:Considering xenogeneic collagen matrix (CM) and enamel matrix derivative (EMD) characteristics, it is suggested that their combination could promote superior clinical outcomes in root coverage procedures. Thus, the aim of this parallel, double-masked, dual-center, randomized clinical trial is to evaluate cli...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2017.170126
更新日期:2017-12-01 00:00:00
abstract::Immunoglobulins in sera and in supernatant fluids of explant cultures of diseased gingival tissues from 20 rapidly progressive and 20 adult periodontitis sites were tested by an ELISA assay for reactivity with typed strains of Eubacterium alactolyticum, E. brachy, E. limosum and E. nodatum. Immunoglobulins present in ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.1.32
更新日期:1988-01-01 00:00:00
abstract::An intraindividual double-blind crossover study was designed in order to see if a 1% chlorhexidine gel used twice a day could substitute for ordinary toothpaste in group of maintenance-care patients with poor oral hygiene. Twenty patients from a student clinic participated, each with a long history of maintenance-care...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1986.57.6.364
更新日期:1986-06-01 00:00:00
abstract::Durapatite particles were employed along with autogenous bone chips to treat an extensive periodontal defect on a mandibular first molar which involved the bifurcation area and the distal root. Nine weeks after treatment the tooth was found to be cracked and was extracted along with tissue containing the grafted sites...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1983.54.8.455
更新日期:1983-08-01 00:00:00
abstract::Periodontal diseases are thought to result from inflammatory responses to bacterial challenges in the gingival crevicular area. Antibodies are a major host-protective mechanism in many bacterial infections. Consequently, the antibody responses to suspected periodontal pathogenic bacteria have been extensively measured...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1993.64.8s.807
更新日期:1993-08-01 00:00:00
abstract:BACKGROUND:The peri-implant soft tissue phenotype (PSP) encompasses the keratinized mucosa width (KMW), mucosal thickness (MT), and supracrestal tissue height (STH). Numerous approaches to augment soft tissue volume around endosseous dental implants have been investigated. To what extent PSP modification is beneficial ...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1002/JPER.19-0716
更新日期:2021-01-01 00:00:00
abstract::A 26-year-old hispanic male presented with a nonspecific gingival lesion initially presumed to be of infectious etiology. During continued follow-up over several weeks, the lesion evolved into one typical of desquamative gingivitis. Direct immunofluorescent testing and routine histopathology resulted in a diagnosis of...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.9.611
更新日期:1988-09-01 00:00:00
abstract::A retrospective study was conducted of 620 patients in a periodontal practice over the years 1960 to 1982. Various periodontal therapies were assessed by using careful office protocols, meticulous record-keeping and well-defined outcome criteria. Four treatment outcome categories were used: two representing satisfacto...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1985.56.5.253
更新日期:1985-05-01 00:00:00
abstract:BACKGROUND:Of the many forms of periodontal disease, refractory periodontal diseases are the least characterized. They are defined as the continued degeneration of the periodontium despite adequate management. This has led to the suggestion that there may be a systemic component that is a contributing factor to the dev...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050108
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to investigate the effect of two modes of delivery of non-surgical periodontal therapy on patient experience of pain and oral health-related quality of life (OHQoL). METHODS:Fifty-nine patients with mild to moderate periodontitis received non-surgical therapy using a piezo-cera...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2008.070394
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Recent research suggests that osteopenia may be a predisposing factor for periodontal tissue destruction. If so, then a relationship should exist between measures of systemic bone mineral density and periodontal tissue destruction. The purpose of the present cross-sectional study was to evaluate the associat...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1999.70.9.982
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:Efficient methods to treat persistent pockets during periodontal maintenance therapy (PMT) require further investigation. The hypothesis of this randomized controlled clinical trial was that local application of enamel matrix derivative (EMD) added to papilla reflection/root preparation (PR/RP) could enhance...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.19-0623
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Porphyromonas gingivalis has been implicated as an etiologic agent of rheumatoid arthritis (RA) because of the expression of peptidylarginine deiminase. The present study evaluates whether periodontal treatment may affect serum antibodies to P. gingivalis and citrulline levels in relation to disease activity...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2013.130079
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:The protease-induced cytotoxicity of P. gingivalis may partly result from alteration of the extracellular matrix and/or surface receptors that mediate interaction between the host cells and their matrix. While P. gingivalis-induced degradation of E-cadherin has been documented, there is no information on the...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2001.72.5.641
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:The minimum inhibitory concentration (MIC) does not provide information on the efficacy of antimicrobial agents against infections involving biofilms, which are many times more resistant than planktonic forms of bacteria. This report is on the design and initial trial of a device for growing standard biofilm...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.9.1443
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:This prospective and controlled study elucidates the impact of smoking on the salivary microbiome and its further influence on marginal bone loss (MBL) around an implant during a 3-month bone-healing period. METHODS:Saliva samples were collected preoperatively from 20 periodontally healthy patients with sin...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2017.160808
更新日期:2017-12-01 00:00:00
abstract::The clinical, histopathologic and functional consequences of the genetic deficiency of leukocyte Mac-1, LFA-1 and p150,95 were assessed among three affected patients, heterozygotes and unaffected individuals among two generations of a single kindred. Longitudinal assessments of this family afforded the unique opportun...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.6.400
更新日期:1987-06-01 00:00:00
abstract:BACKGROUND:The aim of this in vivo study was to evaluate the effects of plaque control on the patency of dentinal tubules using vital teeth of beagle dogs. METHODS:Class V cavities were prepared on the cervical areas of the mandibular and maxillary molars in each dog with a diamond point. To simulate the state of dent...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050159
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Crohn's disease is a chronic inflammatory bowel disease characterized by uncertainty in etiology and pathogenesis occasionally with manifestations in oral mucous membranes. This report reviews the literature on Crohn's disease and presents a patient with Crohn's disease on continuous anti-inflammatory and im...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2003.74.4.537
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Subantimicrobial-dose doxycycline (SDD) is widely used as an adjunctive treatment to scaling and root planing (SRP), but its long-term effectiveness remains controversial. The purpose of this systematic review was to assess the actual evidence of the effectiveness of SRP + SDD compared to SRP + placebo in th...
journal_title:Journal of periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1902/jop.2011.110026
更新日期:2011-11-01 00:00:00
abstract::A technique designed to utilize the autogenous free gingival graft without the use of sutures was demonstrated. Necessary objectives were maintained but achieved without unnecessarily piercing the graft, and in less time. The only variance in results would be due to the underlying physical properties of the recipient ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1979.50.2.75
更新日期:1979-02-01 00:00:00
abstract::The one-year results of a regenerative procedure in patients treated with or without antibiotics are presented. Expanded polytetrafluoroethylene (ePTFE) was placed over mandibular molar Class II furcation invasions and retained for four weeks. The patients in group 1 received no antibiotics; patients in group 2 receiv...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1994.65.7.713
更新日期:1994-07-01 00:00:00
abstract::The research reviewed in this paper constitutes a series of investigations intended to develop and evaluate a new membrane technique, which provides improved conditions for osteogenesis during healing of bone defects and restitution of earlier existing bone. The technique has also been shown to aid in bone grafting as...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1993.64.11s.1116
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:To determine the level of perceived pain after different types of periodontal/oral surgical procedures, and the differences in patients' selection of pain management, over the counter (OTC) versus opioid, based on procedure type. METHODS:Patients undergoing surgical procedures were asked to complete a pain ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.20-0315
更新日期:2020-11-05 00:00:00
abstract:BACKGROUND:Earlier studies have shown an association between obesity and periodontitis, which is mediated by cytokine production. The aim of this study is to assess the role of obesity as a modifying factor on periodontal clinical parameters and on circulating proinflammatory cytokine levels in subjects undergoing non-...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100545
更新日期:2011-05-01 00:00:00
abstract::This study investigated variations in occlusal prematurities and condylar positions using different methods of determining centric relation. Thirty patients were randomly placed into three groups of 10. In Group I a clinical analysis of occlusal patterns using bilateral mandibular manipulation (BMM) was compared to re...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1981.52.7.347
更新日期:1981-07-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to evaluate the effect of strict supragingival plaque control on the subgingival microbiota in smokers and never-smokers. Research into the impact of supragingival plaque control on the number of subgingival bacteria has resulted in contradictory findings. Real-time polymeras...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.2008.070558
更新日期:2008-12-01 00:00:00
abstract::This report describes the case of a 21-year-old female who presented with localized gingival ulceration that over a period of 4 weeks became generalized, affecting all the buccal gingiva as well as the lower lip. A detailed medical history suggested that the patient was generating the lesions herself. She was monitore...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1994.65.5.442
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:One endpoint of periodontal therapy is to regenerate the structure lost due to periodontal disease. In the periodontium, gingival epithelium is regenerated by oral epithelium. Underlying connective tissue, periodontal ligament, bone, and cementum are derived from connective tissue. Primitive connective tissu...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.12.2194
更新日期:2005-12-01 00:00:00