Abstract:
:The one-year results of a regenerative procedure in patients treated with or without antibiotics are presented. Expanded polytetrafluoroethylene (ePTFE) was placed over mandibular molar Class II furcation invasions and retained for four weeks. The patients in group 1 received no antibiotics; patients in group 2 received amoxicillin/clavulanate potassium during the first 10 post-operative days. The initial differences in tested microorganisms and post-surgical inflammation indicated that the use of the antibiotic might enhance the long-term outcome. After one year, the reduction in mean probing depth of the furcation invasions was 2.0 +/- 1.2 mm for group 1 and 1.8 +/- 1.1 mm for group 2. An overall gain of 0.8 mm of clinical attachment was found. Twenty-two of the 24 sites were re-entered. Wide individual variations were found but the changes between pre-treatment and one-year data for any of 6 linear measurements of hard tissue landmarks did not differ between groups or between pre-treatment and re-entry. A combination of an overall loss of 0.4 mm alveolar bone at the crest and 0.3 mm gain of bone at the bottom of the furcation defects was found. Volumetric analysis indicated an average 32% bone fill for both groups, ranging from a decrease in defect volume by 84% (gain) to an increase of the size of the furcation invasion by 66% (loss). A decrease in defect volume > 30% was found at 7 sites from each group. The antibiotic may have controlled initial inflammation, but 12 months later it had no direct effect on bone regeneration or soft tissue attachment.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Demolon IA,Persson GR,Ammons WF,Johnson RHdoi
10.1902/jop.1994.65.7.713subject
Has Abstractpub_date
1994-07-01 00:00:00pages
713-7issue
7eissn
0022-3492issn
1943-3670journal_volume
65pub_type
临床试验,杂志文章abstract::The aim of the present study was to clinically and radiographically compare guided tissue regeneration (GTR) therapy with bioabsorbable polyglactin 910 barriers and conventional periodontal surgery in intrabony defects. In 26 patients with advanced periodontitis, 29 teeth exhibiting interproximal intrabony defects wer...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1998.69.11.1210
更新日期:1998-11-01 00:00:00
abstract:BACKGROUND:A disintegrin and metalloproteinase 28 (ADAM28) is considered to be the possible virulence gene for congenital hypoplasia of tooth root. Periodontal ligament stem cells (PDLSCs) are regarded as playing crucial roles in the developing process of the periodontium and are generally used in dental regenerative m...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.090703
更新日期:2010-06-01 00:00:00
abstract::The sensitivity to tetracycline of 345 bacterial isolates from periodontal lesions was determined. Most species of bacteria, including those thought to be involved in the initiation and progress of destructive periodontal disease, were inhibited in vitro by tetracycline concentrations of 4 to 8 micrograms/ml. This con...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1981.52.10.613
更新日期:1981-10-01 00:00:00
abstract::The autogenous tooth transplantation approach to replace missing teeth has been in use for a long time. Different surgical techniques have been developed to improve prognosis and longevity of transplanted teeth with complete root formation. Many factors reportedly affected short- and long-term success of the procedure...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2017.160820
更新日期:2017-06-01 00:00:00
abstract::The report is a review of the literature related to hepatitis B and its implications for dental practitioners. Hepatitis B represents a serious health risk among dentists and simple preventive measures can greatly reduce the risk of transmission or contraction of the disease. Certain positive findings in a healthy his...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1980.51.3.162
更新日期:1980-03-01 00:00:00
abstract::The purpose of this investigation was to evaluate calcium hydroxide and potassium nitrate individually as densensitizing agents for hypersensitive root surfaces. The apparatus used in the experiment to measure hypersensitivity was (a) a thermo-electric stimulating device to measure hot and cold stimulation quantitativ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1977.48.10.667
更新日期:1977-10-01 00:00:00
abstract:BACKGROUND:It has been shown that different implant designs and different vertical implant positions have an influence on crestal bone levels. The aim of the present study was to evaluate radiographic crestal bone changes around experimental dental implants with non-matching implant-abutment diameters placed submucosal...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.070132
更新日期:2008-02-01 00:00:00
abstract::This study investigates the effects of the placement of a bioresorbable Type I collagen barrier on clinically healthy sites. Ten human subjects, with at least one pair of matched periodontal defects included in a previous study, were investigated for the effect of guided tissue regeneration (GTR) membrane placement on...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.1.57
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:This cross-sectional study assesses cytokine levels in peri-implant crevicular fluid (PICF)/gingival crevicular fluid (GCF) and a selection of subgingival/submucosal plaque bacteria from clinically healthy or diseased sites in the same individuals. METHODS:Samples from 97 implants/teeth (58 implants [19 hea...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2017.160751
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:This study aims to identify predictors of performed oral hygiene behaviors (OHBs) based on the Theory of Planned Behavior (TPB), oral health knowledge, and demographic factors. METHODS:Using a questionnaire, 381 participants in three general dental offices and one hospital dental department in York, Pennsyl...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2015.150239
更新日期:2016-03-01 00:00:00
abstract::Interleukin-1 beta (IL-1 beta) is the predominant form of IL-1 produced by macrophages. IL-1 beta possesses numerous and diverse biological activities. Several of these activities, including fibroblast proliferation, potentiation of the immune response, and stimulation of bone resorption may be of relevance to the pat...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1991.62.1.36
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Periodontitis is an infection with an episodic pattern of tissue-support destruction. During the generation of a primary CD4(+) T helper 1 (Th1) response, interferon-gamma (IFN-gamma) acts as a positive regulator by selectively inducing Th1 differentiation through increased transcription of T-bet. The aims o...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2009.080287
更新日期:2009-02-01 00:00:00
abstract::Gingival biopsies of the mesial papilla area of the first molar were obtained from each patient at 0-, 14- and 21-day intervals during plaque formation. The biopsies were fixed, serially sectioned, and Gram-stained. The incidence and distribution of the bacteria-like structures were studied by microscopy. In all the s...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.12.837
更新日期:1987-12-01 00:00:00
abstract::An increasing body of evidence supports the concept that host-produced PGE2 mediates much of the tissue destruction that occurs in periodontal disease. PGE2 levels within the crevicular fluid can serve as a static assessment of ongoing disease activity; i.e., rate of attachment loss and bone resorption. New insights i...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.5s.432
更新日期:1993-05-01 00:00:00
abstract::THE MAXILLARY anterior region presents a difficult and unique therapeutic challenge to both the periodontist and restorative dentist. Although access for surgical and prosthetic procedures is certainly easiest in this part of the mouth, the problem of esthetics, in terms of increased tooth length and loss of interdent...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1981.52.4.208
更新日期:1981-04-01 00:00:00
abstract:BACKGROUND:Reparative tissue of extraction sockets was proposed as grafting material in the treatment of periodontal defects. Our hypothesis was that the addition of growth factors to extraction sockets improves the regenerative potential of this tissue when used as a graft. The objective of the present study was to an...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.10.1681
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Ossifying fibromyxoid tumors (OFTs) are uncommon soft tissue neoplasms. Only one case arising in the gingiva has been described. METHODS:A 21-year-old woman presented with a painless exophytic mass located in the right posterior mandibular gingiva, which was identified 6 months earlier. Radiographs showed i...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2009.080535
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:This study evaluated patients who had been treated with recombinant human bone morphogenetic protein-2 (rhBMP-2) loaded in an absorbable collagen sponge (ACS) in human extraction sites or in sites that required alveolar ridge augmentation. An earlier report on the same patients revealed that after 4 months, ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.2000.71.8.1241
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Osteoblasts and periodontal ligament stem cells (PDLSCs) play an important role in maintaining physiologic function of periodontal tissues and participating in periodontal regeneration. Elucidation of interactions between osteoblasts and PDLSCs will aid understanding of periodontal regeneration mechanisms. T...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2017.170016
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Simvastatin has been shown to stimulate new bone growth on rat mandibles, but much of the bone is lost over time. The purpose of this study is to evaluate the impact of a locally or systemically applied antiresorptive agent (alendronate) on simvastatin-induced bone formation in and adjacent to a rat periodon...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.110683
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Some studies have advocated marrow penetration in guided bone augmentation (GBA), whereas others have shown that bone can be generated without marrow penetration. This study examined the effect of marrow penetration and the optimal rate of penetration. METHODS:In 10 rabbits, the calvarium was exposed, and c...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.070086
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Periodontitis and osteoporosis are characterized by the loss of bone mass. Osteocalcin levels have been postulated as a marker of inhibition of bone formation. The aim of the present study was to assess plasma, saliva, and gingival crevicular fluid (GCF) levels of osteocalcin and correlate them with periodon...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.4.513
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:Smoking is a major risk factor for periodontal disease. Conventional oral epidemiology approaches have found strong, consistent associations between chronic smoking and periodontal attachment loss (AL) through ages 26, 32, and 38 years, but those statistical methods disregarded the data's hierarchical struct...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2014.130577
更新日期:2014-10-01 00:00:00
abstract::There are only a few long-term investigations on root-resected teeth in the literature. This article is a 10-year review of 28 root-resection cases, which mainly had been used as bridge abutments. The periodontal, prosthetic, and endodontic problems were evaluated. After 10 years a total failure rate of 32% was observ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.12.805
更新日期:1988-12-01 00:00:00
abstract:BACKGROUND:Systemic bone loss has been proposed as a risk factor for periodontal disease; however, the relationship between these two diseases is still not clear. The objective of this study was to assess the relationship between systemic bone mineral density and periodontal disease, controlling for known confounders. ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.9.1492
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Mechanical periodontal therapy consists of a non-surgical course, followed by surgical treatment to eliminate or reduce remaining pathological pockets. Only if diligent mechanical therapy fails are additional measures considered. It has been documented that smoking interferes with the host defense mechanisms...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.10.1166
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the total antioxidant capacity, superoxide dismutase and glutathione peroxidase activities, and malondialdehyde levels in serum, saliva, and gingival crevicular fluid (GCF) in preeclamptic and normotensive pregnant women with and without periodontal disease. METHODS:...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.060469
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Periodontitis is a suspected environmental risk factor for the development of rheumatoid arthritis (RA). However, correlation mechanisms between the two pathologies remain elusive. This study examined potential correlations between detached subgingival bacteria collected in gingival crevicular fluid (GCF) an...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.20-0295
更新日期:2020-07-31 00:00:00
abstract:BACKGROUND:There has been an explosion in research into possible associations between periodontitis and various systemic diseases and conditions. AIM:To review the evidence for associations between periodontitis and various systemic diseases and conditions, including chronic obstructive pulmonary disease (COPD), pneum...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.1340020
更新日期:2013-04-01 00:00:00
abstract::Palatal groove is a rare morphological defect of upper incisors, frequently associated with localized destruction of periodontal tissue with endodontic complications. In this study, a sample of 1,081 male, young adult subjects, aged 20 to 22, palatal grooving was recorded in 11 (1.01%) subjects, affecting 15 incisors....
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1990.61.3.197
更新日期:1990-03-01 00:00:00