Abstract:
BACKGROUND:Systemic bone loss has been proposed as a risk factor for periodontal disease; however, the relationship between these two diseases is still not clear. The objective of this study was to assess the relationship between systemic bone mineral density and periodontal disease, controlling for known confounders. METHODS:The study population included 70 postmenopausal Caucasian women aged 51 to 78 (mean +/- SD: 62.10 +/- 7.1 years). Skeletal bone mineral density (BMD) was assessed by dual energy x-ray absorptiometry (DXA) at the neck, trochanter, intertrochanter, Ward's triangle, and total regions of the femur, and from the anterior-posterior view of the lumbar spine. Periodontal disease severity was represented by clinical attachment loss (CAL) and interproximal alveolar bone loss (ABL). Other measures of periodontal status included probing depth (PD), supragingival plaque, gingival bleeding on probing, and calculus. DXA and oral examinations were performed by calibrated examiners. Partial correlation coefficients (r) were obtained from multiple linear regression analysis adjusting for age, age at menopause, estrogen supplementation, cigarette smoking, body mass index, and supragingival plaque. RESULTS:Mean ABL was significantly correlated with BMD of the trochanter (r =- 0.27), Ward's triangle (r = -0.26), and total regions of the femur (r = -0.25). Mean CAL appeared to be related to BMD consistently at all regions of the skeleton, although the association did not reach statistical significance. CONCLUSIONS:We can conclude that skeletal BMD is related to interproximal alveolar bone loss and, to a lesser extent, to clinical attachment loss, implicating postmenopausal osteopenia as a risk indicator for periodontal disease in postmenopausal Caucasian women.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Tezal M,Wactawski-Wende J,Grossi SG,Ho AW,Dunford R,Genco RJdoi
10.1902/jop.2000.71.9.1492subject
Has Abstractpub_date
2000-09-01 00:00:00pages
1492-8issue
9eissn
0022-3492issn
1943-3670journal_volume
71pub_type
杂志文章abstract::This investigation was conducted on seven individuals referred for treatment of moderate adult periodontitis. Twenty-eight sites with an average probing depth of 5.6 +/- 0.9 mm were evaluated. One tooth per jaw quadrant was randomly assigned to receive one of the following treatments: (I) no treatment, i.e., control; ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1988.59.5.301
更新日期:1988-05-01 00:00:00
abstract:BACKGROUND:The need for keratinized mucosa (KM) or immobile keratinized mucosa (i.e., attached mucosa [AM]) for the maintenance of osseointegrated endosseous dental implants has been controversial. The purpose of this study was to investigate the significance of KM in the maintenance of root-form dental implants with d...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050393
更新日期:2006-08-01 00:00:00
abstract::Plasma cells are widely distributed in inflamed periodontal tissues, the adjacent periodontal ligament and nearby alveolar bone spaces, of old rats (20 and 27 months) raised on a conventional diet in a normal laboratory environment. Electron microscopy revealed three morphologic types (or perhaps stages) of these cell...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1983.54.4.227
更新日期:1983-04-01 00:00:00
abstract:BACKGROUND:Periodontists have found the gingival autograft to be an effective and predictable technique to increase the amount of attached gingiva around teeth, but this technique requires the surgeon to harvest donor tissue from a remote surgical site. The present study seeks to evaluate the safety and effectiveness o...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2005.76.6.867
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:The aim of this study is to evaluate the levels of serum lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) and high-sensitivity C-reactive protein (hsCRP) in association with periodontal disease and hyperlipidemia. METHODS:A total of 123 subjects with hyperlipidemia and 68 systemically healthy controls ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100417
更新日期:2011-03-01 00:00:00
abstract::An increased incidence of antibiotic-resistant bacteria and yeast overgrowth has been reported following various periodontal treatments. The objective of this study was to detect possible overgrowth of opportunistic bacteria and fungi as well as changes in normal microbiota after application of a biodegradable deliver...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1995.66.10.870
更新日期:1995-10-01 00:00:00
abstract::T-cell subsets extracted from chronically inflamed periodontal tissues were identified using monoclonal antibodies, and their functional activity was analysed using the autologous mixed lymphocyte reaction (AMLR). Tissue was obtained from a total of 33 adult periodontitis (AP) patients and 6 normal/marginal gingivitis...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.8.569
更新日期:1987-08-01 00:00:00
abstract:BACKGROUND:The comparative treatment response of children and young adults with localized aggressive periodontitis treatment (LAgP) affecting primary and permanent dentition is unknown. The objective of this study is to evaluate the influence of non-surgical periodontal therapy with adjunctive systemic antibiotics on t...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.2014.140171
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Chronic exposure to occupational noise is reported to cause a wide range of health problems. But, there are no reports on studies investigating the association between noise exposure and periodontitis. The purpose of this study was to examine the relationship between occupational noise exposure and periodont...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.17-0484
更新日期:2018-04-01 00:00:00
abstract::A small laser doppler probe with an outside diameter comparable to a conventional periodontal probe (0.5 mm) was developed. The objectives of this investigation were to determine if intrasulcular laser doppler readings (LDR): 1) are reproducible; 2) can detect vascular changes associated with trauma from probe placeme...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1995.66.3.171
更新日期:1995-03-01 00:00:00
abstract::Despite the improvement in the patients' oral hygiene, there was no significant decrease in the frequency of bacteremia. There was no significant difference in bacteremia between brushing, flossing, or deplaquing either before or after initial periodontal preparation and plaque control in 21 healthy subjects. Utilizin...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1976.47.12.683
更新日期:1976-12-01 00:00:00
abstract:BACKGROUND:A specific composite genotype of the polymorphic interleukin-1 (IL-1) gene cluster has recently been associated with severe periodontitis. One polymorphism of the composite periodontitis-associated genotype (PAG) has been functionally linked with expression of high levels of IL-1. The purpose of this study w...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.6.567
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND:Hyperlipidemia is a known risk factor for cardiovascular diseases. A common biologic mechanism between systemic diseases, such as cardiovascular diseases, and periodontal diseases has been suggested. The aim of this study is to examine the association between blood lipid profile and periodontitis. METHODS:T...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2017.170111
更新日期:2018-01-01 00:00:00
abstract::The feasibility of a new combined collagen gel-autolysed antigen-extracted allogeneic bone implant was tested. Its effect on gaining new attachment in surgically created defects in four dogs was evaluated over 24 weeks. As controls, sites receiving implants of the bone implant alone, nonimplanted and untreated defects...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1986.57.2.84
更新日期:1986-02-01 00:00:00
abstract:BACKGROUND:Maintaining normal weight, engaging in the recommended level of exercise, and eating healthy food are known to improve general health. The impact of these behaviors on periodontal health is not well documented. This study is aimed at examining whether the increased number of these behaviors is associated wit...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.8.1362
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:Earlier publications from our laboratory described the use of guided bone regeneration to fill large bone voids in the mandible created through en bloc resection in primates. The present report describes placement of implants into the regenerated bone with subsequent prostheses construction and loading. MET...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2001.72.6.703
更新日期:2001-06-01 00:00:00
abstract::A case of osseous hyperplasia under the pontics of fixed partial dentures in right and left mandibular first molar regions is presented. Radiographs showed hemispherical radio-opacities on the alveolar ridges. Histologic examination revealed the lesions were composed of a dense mass of mature bone with well-developed ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.5.311
更新日期:1988-05-01 00:00:00
abstract:BACKGROUND:Alternative therapeutic approaches have been explored to modulate host response to periodontal disease. Knowledge of new strategies to treat periodontitis is particularly relevant in patients presenting augmented risk to periodontitis, such as smokers. The aim of this study is to investigate the impact of re...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2017.170025
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Previous studies have demonstrated that enamel matrix derivative (EMD) has the ability to improve clinical parameters when used to treat intraosseous defects. The purpose of the present study was to compare at 12 months postsurgery sites treated with open flap debridement (OFD) alone to those treated with OF...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2001.72.1.25
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:The aims of this study are to determine whether the antigen-inexperienced (naive, CD45RB high-density) T-cell (CD4(+)CD45RB(High) T-cell) transfer model is associated with alveolar bone resorption, to elucidate the local osteogenic/adipogenic potential of alveolar bone marrow stromal cells (ABCs) from T-cell...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2014.140077
更新日期:2014-09-01 00:00:00
abstract::Invasion of gingival tissues by bacteria is thought to be a major factor in development of periodontal lesions. Morphologic studies have revealed bacteria within the pocket epithelium, gingival connective tissues, alveolar bone, and oral epithelium. The current studies are intended to determine whether they are presen...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1990.61.1.35
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study is to evaluate the safety, patient acceptance, and short-term microbiologic effect of a new air-polishing device in subjects in maintenance care with residual pockets > or =5 mm. METHODS:This was an examiner-masked, randomized, split-mouth clinical trial. A new disposable nozzle, a...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2009.090394
更新日期:2010-01-01 00:00:00
abstract::In this investigation periodontal destruction was produced by a combination of inflammatory and traumatic factors. After the inflammation was resolved and the trama stopped, a significant amount of alveolar bone regeneration took place. The implications of these findings for the management of advanced periodontal dise...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1976.47.12.687
更新日期:1976-12-01 00:00:00
abstract::A multitude of new procedures and materials are being tested for their ability to promote periodontal wound healing. This review provides an overview of the most well-accepted methods for evaluating periodontal wound healing procedures/materials. Topics discussed include appropriate patient selection, general principl...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1992.63.12s.1085
更新日期:1992-12-01 00:00:00
abstract::The purpose of this investigation was to evaluate calcium hydroxide and potassium nitrate individually as densensitizing agents for hypersensitive root surfaces. The apparatus used in the experiment to measure hypersensitivity was (a) a thermo-electric stimulating device to measure hot and cold stimulation quantitativ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1977.48.10.667
更新日期:1977-10-01 00:00:00
abstract::This study examined histologic and histometric responses to 2 bioabsorbable membranes made from a synthetic copolymer of glycolide and lactide. They were tested for their biocompatibility, resorption characteristics, and ability to support periodontal regeneration. Expanded polytetrafluoroethylene (ePTFE) was used as ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1994.65.6.583
更新日期:1994-06-01 00:00:00
abstract:BACKGROUND:The goal of guided tissue regeneration-based root coverage (GTRC) is to repair gingival recession via new attachment formation. Numerous clinical trials have been conducted utilizing the concept of GTR to promote root coverage. Most GTRC studies have had relatively small sample sizes and have not utilized po...
journal_title:Journal of periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1902/jop.2003.74.10.1520
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Lingual plate perforation at the time of implant placement in posterior mandible is a potential surgical complication, and presence of a lingual concavity is considered a risk factor. Little is known about the spatial relationship between implant and lingual plate. The role of lingual concavity in the risk o...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100313
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Prefabricated implant abutments made of zirconium dioxide (yttria-stabilized polycrystalline tetragonal zirconia; Y-TZP) have proved to be useful in the esthetically demanding anterior region and may also be useful for premolar and molar replacement because of their obvious positive impact on the health of p...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2009.090274
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:This study evaluated patients who had been treated with recombinant human bone morphogenetic protein-2 (rhBMP-2) loaded in an absorbable collagen sponge (ACS) in human extraction sites or in sites that required alveolar ridge augmentation. An earlier report on the same patients revealed that after 4 months, ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.2000.71.8.1241
更新日期:2000-08-01 00:00:00