Abstract:
:Acute encephalitis is a severe neurologic syndrome. Determining etiology from among ≈100 possible agents is difficult. To identify infectious etiologies of encephalitis in Thailand, we conducted surveillance in 7 hospitals during July 2003-August 2005 and selected patients with acute onset of brain dysfunction with fever or hypothermia and with abnormalities seen on neuroimages or electroencephalograms or with cerebrospinal fluid pleocytosis. Blood and cerebrospinal fluid were tested for >30 pathogens. Among 149 case-patients, median age was 12 (range 0-83) years, 84 (56%) were male, and 15 (10%) died. Etiology was confirmed or probable for 54 (36%) and possible or unknown for 95 (64%). Among confirmed or probable etiologies, the leading pathogens were Japanese encephalitis virus, enteroviruses, and Orientia tsutsugamushi. No samples were positive for chikungunya, Nipah, or West Nile viruses; Bartonella henselae; or malaria parasites. Although a broad range of infectious agents was identified, the etiology of most cases remains unknown.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Olsen SJ,Campbell AP,Supawat K,Liamsuwan S,Chotpitayasunondh T,Laptikulthum S,Viriyavejakul A,Tantirittisak T,Tunlayadechanont S,Visudtibhan A,Vasiknanonte P,Janjindamai S,Boonluksiri P,Rajborirug K,Watanaveeradej V,Khetsurdoi
10.3201/eid2102.140291subject
Has Abstractpub_date
2015-02-01 00:00:00pages
280-9issue
2eissn
1080-6040issn
1080-6059journal_volume
21pub_type
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