Abstract:
:Neurologic abnormalities were seen in 13 of 20 patients with a history of chronic solvent vapor (primarily toluene) abuse for 2 or more years. The patients were evaluated after an abstinence period of at least 4 weeks, to avoid neurologic effects of acute intoxication. Neurologic signs included cognitive (60%), pyramidal (50%), cerebellar (45%), and brainstem/cranial nerve (25%) findings. Eight of nine CTs revealed diffuse atrophy of cerebral hemispheres, cerebellum, and brainstem. BAERs were abnormal in three of four patients, and EEG abnormalities were seen in three of seven patients. Chronic exposure to solvent vapor may cause persistent neurologic impairment.
journal_name
Neurologyjournal_title
Neurologyauthors
Hormes JT,Filley CM,Rosenberg NLdoi
10.1212/wnl.36.5.698subject
Has Abstractpub_date
1986-05-01 00:00:00pages
698-702issue
5eissn
0028-3878issn
1526-632Xjournal_volume
36pub_type
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