Abstract：
:There is considerable variability among people in their response to bereavement. While most people adapt well to bereavement, some develop exaggerated and/or pathological responses and may meet criteria for a major depressive episode. Many studies have investigated the effect of psychosocial factors on bereavement outcome but biological factors have not received much attention, hence the focus of this paper. The biological factors studied to date in relation to bereavement outcomes include genetic polymorphisms, neuroendocrine factors, and immunologic/inflammatory markers. In addition, animal studies have shown the alterations of brain neurotransmitters as well as changes in the plasma levels of the neurotrophic growth factors under the influence of peer loss. Recent studies have also investigated the biological basis of stress resilience, and have found a few genetic polymorphisms and potential biomarkers as protective factors in the face of adversity. Longitudinal studies that include data collection prior to, and also after, bereavement and which chart both biological and psychological measures are needed to develop profiles for the prediction of response to bereavement and personalised interventions.
journal_name
Neurosci Biobehav Revjournal_title
Neuroscience and biobehavioral reviewsauthors
Assareh AA,Sharpley CF,McFarlane JR,Sachdev PSdoi
10.1016/j.neubiorev.2014.12.013subject
Has Abstractpub_date
2015-02-01 00:00:00pages
171-81eissn
0149-7634issn
1873-7528pii
S0149-7634(14)00352-2journal_volume
49pub_type
杂志文章,评审abstract：:An extensive body of research suggests the spontaneous eye blink rate (EBR) is a non-invasive indirect marker of central dopamine (DA) function, with higher EBR predicting higher DA function. In the present review we provide a comprehensive overview of this literature. We broadly divide the available research in studi...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2016.08.020
更新日期：2016-12-01 00:00:00
abstract：:Physiological and behavioral reproductive changes in the female rat which occur under constant bright illumination (LL) are examined. The development of LL-induced persistent estrus (PE) is discussed first in relation to other conditions in which PE is displayed. Next, mechanisms are reviewed which may account for the...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/0149-7634(82)90049-5
更新日期：1982-10-01 00:00:00
abstract：:The aim of this systematic review was to summarize the effects of physical exercise on neuropathic pain (NP) in animal models of SCI. The search was conducted in Medline and Science Direct to identify experimental preclinical studies involving animal models of SCI, physical exercise as an intervention and the assessme...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,meta分析
doi：10.1016/j.neubiorev.2019.12.016
更新日期：2020-01-01 00:00:00
abstract：:Deep brain stimulation (DBS) is remarkably effective for a range of neurological and psychiatric disorders that have failed pharmacological and cell transplant therapies. Clinical investigations are underway for a variety of other conditions. Yet, the therapeutic mechanisms of action are unknown. In addition, DBS rese...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2007.06.003
更新日期：2008-01-01 00:00:00
abstract：:The phenomenology and underlying pathophysiology of bipolar disorder (BD) are heterogeneous. The identification of putative endophenotypes for BD can aid in the investigation of unique patho-etiological pathways, which may lead to the development of personalised preventative and therapeutic approaches for this multi-f...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2016.12.011
更新日期：2017-02-01 00:00:00
abstract：:One of the core diagnostic criteria for Dementia with Lewy Bodies (DLB) is the presence of visual hallucinations. The presence of hallucinations, along with fluctuations in the level of arousal and sleep disturbance, point to potential pathological mechanisms at the level of the thalamus. However, the potential role o...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2019.06.006
更新日期：2019-08-01 00:00:00
abstract：:Experimental evidence is reviewed for the implication in aversive learning of the catecholamines, in particular noradrenaline and dopamine and the pituitary-adrenocortical system, in particular adrenocorticotrophic hormone and corticosterone. Depending on task difficulty peripheral neural noradrenaline may be an impor...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/0149-7634(80)90014-7
更新日期：1980-07-01 00:00:00
abstract：:It has long been known that the estrogen, 17β-estradiol (17β-E), plays a central role for female reproductive physiology and behavior. Numerous studies have established the neurochemical and molecular basis of estrogenic induction of female sexual behavior, i.e., lordosis, in animal models. In addition, 17β-E also reg...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2018.10.012
更新日期：2020-03-01 00:00:00
abstract：:Insulin receptors are known to be located on nerve cells in mammalian brain. The binding of insulin to dimerized receptors stimulates specialized transporter proteins that mediate the facilitated influx of glucose. However, neurons possess other mechanisms by which they obtain glucose, including transporters that are ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(00)00040-3
更新日期：2000-12-01 00:00:00
abstract：:Although human aggression is frequently inferred to parallel aggression based on testosterone in nonprimate mammals, there is little concrete support for this position. High- and low-aggression individuals do not consistently differ in serum testosterone. Aggression does not change at puberty when testosterone levels ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(05)80117-4
更新日期：1993-01-01 00:00:00
abstract：:The possible implication of 5-HT2 receptors in CNS disorders such as schizophrenia, anxiety and depression suggests that 5-HT2 antagonists may be useful in the treatment of these disorders. The present review examines behavioral procedures used to characterize 5-HT2 antagonist properties of compounds and behavioral mo...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(05)80056-9
更新日期：1992-04-01 00:00:00
abstract：:In ingestive taste reactivity analysis, the rhythmic oral motor responses observed during intraoral infusion of fluids normally ingested by rats are categorized and counted. These rhythmic movements can be likened to spout-licking in several respects. Both are emitted in the same frequency range (5-8 Hz), organized in...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/0149-7634(94)00023-t
更新日期：1995-04-01 00:00:00
abstract：:There are roughly 30-40 million HIV-infected individuals in the world as of December 2007, and drug abuse directly contributes to one-third of all HIV infections in the United States. Antiretroviral therapy has increased the lifespan of HIV-seropositives, but CNS function often remains diminished, effectively decreasi...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2008.01.004
更新日期：2008-07-01 00:00:00
abstract：:Maternal obesity in pregnancy is associated with neurobehavioral problems in the offspring. Establishing causality has been challenging in existing human studies, due to confounding by genetic and postnatal environment. Animal experiments can improve our understanding of this association. This systematic review examin...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/j.neubiorev.2018.12.023
更新日期：2019-03-01 00:00:00
abstract：:Human infants are particularly responsive to olfactory cues emanating from their mother's nipple/areola region. Beginning within minutes after birth, maternal breast odors elicit preferential head orientation by neonates and help guide them to the nipple. Such odors also influence babies' general motor activity and ar...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(98)00044-x
更新日期：1999-01-01 00:00:00
abstract：:The thalamus, with its cortical, subcortical, and cerebellar connections, is a critical node in networks supporting cognitive functions known to decline in normal aging, including component processes of memory and executive functions of attention and information processing. The macrostructure, microstructure, and neur...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2015.03.008
更新日期：2015-07-01 00:00:00
abstract：:Dopamine hypotheses of several psychiatric disorders are based upon the clinical benefits of drugs affecting dopamine transporter or receptors, and have prompted intensive candidate gene research within the dopaminergic system during the last two decades. The aim of this review is to survey the most important findings...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2011.04.002
更新日期：2011-08-01 00:00:00
abstract：:Yawning is a phylogenetically old behaviour that can be observed in most vertebrate species from foetal stages to old age. The origin and function of this conspicuous phenomenon have been subject to speculations for centuries. Here, we review the experimental evidence for each of these hypotheses. It is found that the...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2010.03.008
更新日期：2010-07-01 00:00:00
abstract：:Adolescence as highlighted in this special issue is a period of tremendous growth, synaptic exuberance, and plasticity, but also a period for the emergence of mental illness and addiction. This commentary aims to stimulate research on prevention science to reduce the impact of early life events that often manifest dur...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/j.neubiorev.2016.07.012
更新日期：2016-11-01 00:00:00
abstract：:Response inhibition has been shown to be associated with monoamine-related gene polymorphisms, although evidence is inconclusive. To comprehensively examine these genotype effects on behavioural correlates of response inhibition in non-clinical adult populations, we performed a two-step approach. A systematic review o...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.neubiorev.2017.11.009
更新日期：2018-01-01 00:00:00
abstract：:Handedness is a dynamic and complex aspect of human behavior. Changing it through practice, either willingly or obliged by some reason, requires a considerable amount of effort. Analyzing studies that presented handedness shifts may expand our comprehension of this phenomenon, since knowing how to change it might prov...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2019.09.019
更新日期：2019-12-01 00:00:00
abstract：:Prompted by recent findings suggesting that the basal ganglia and possibly the limbic midbrain area and brainstem reticular formation may be represented within the general learning system of the rat brain, the current study was undertaken to assess the learning ability of different groups of young rats prepared with b...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/s0149-7634(87)80011-8
更新日期：1987-01-01 00:00:00
abstract：:The gene coding for the dopamine transporter (DAT), SLC6A3, contains a 40-base pair variable number of tandem repeats (VNTR) polymorphism (rs28363170) in its 3' untranslated region. This VNTR has been associated with attention deficit hyperactivity disorder (ADHD) and has been investigated in relation to cognition and...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.neubiorev.2015.09.021
更新日期：2016-01-01 00:00:00
abstract：:The effect of adding 0.125% saccharin to 3% or 32% solutions of Polycose, sucrose and glucose on the fluid intake and preference of adult female rats was examined. In Experiment 1, the rats consumed more of a 3% Polycose + 0.125% saccharin solution (P + s) than of either a 3% Polycose or 0.125% saccharin solution; sim...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/s0149-7634(87)80030-1
更新日期：1987-07-01 00:00:00
abstract：:The study of 5-hydroxytryptamine (5-HT) system has benefited from the identification, classification and cloning of multiple 5-HT receptors (5-HT1 to 5-HT7). Growing evidence suggests that 5-HT is important in learning and memory and all its receptors might be implicated in this. Actually, 5-HT pathways, 5-HT reuptake...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(99)00067-6
更新日期：1999-12-01 00:00:00
abstract：:Clinical and pre-clinical evidence has implicated neuregulin 1 (NRG1) as a critical component in the pathophysiology of schizophrenia. However, the arrival of the genome-wide association study (GWAS) era has yielded results that challenge the relevance of NRG1 in schizophrenia due to the absence of a genome-wide signi...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2016.06.001
更新日期：2016-09-01 00:00:00
abstract：:Two major consequences of placentophagia, the ingestion of afterbirth materials that occurs usually during mammalian parturition, have been uncovered in the past several years. The first is that increased contact, associated with ingesting placenta and amniotic fluid from the surface of the young, causes an accelerate...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(05)80035-1
更新日期：1991-10-01 00:00:00
abstract：:In Parkinson's disease, together with the classic loss of dopamine neurons of the substantia nigra pars compacta, neuropathological studies and biochemical findings documented the occurrence of a concomitant significant cell death in the locus coeruleus. This review analyzes the latest data obtained from experimental ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(00)00028-2
更新日期：2000-08-01 00:00:00
abstract：:Males of many animal species perform specialized courtship behaviours to gain copulations with females. Identifying physiological and anatomical specializations underlying performance of these behaviours helps clarify mechanisms through which sexual selection promotes the evolution of elaborate courtship. Our knowledg...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2014.07.017
更新日期：2014-10-01 00:00:00
abstract：:Risk assessment is the attempt to characterize the chance of obtaining an adverse effect after exposure to an agent. Traditionally, high levels of an agent have been used to estimate the likelihood a lower dose might have an effect either by using low-dose extrapolation models or by attempting to establish a dose with...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/s0149-7634(05)80108-3
更新日期：1991-04-01 00:00:00
