Abstract：
:Adolescence as highlighted in this special issue is a period of tremendous growth, synaptic exuberance, and plasticity, but also a period for the emergence of mental illness and addiction. This commentary aims to stimulate research on prevention science to reduce the impact of early life events that often manifest during adolescence. By promoting a better understanding of what creates a normal and abnormal trajectory, the reviews by van Duijvenvoorde et al., Kilford et al., Lichenstein et al., and Tottenham and Galvan in this special issue comprehensively describe how the adolescent brain develops under typical conditions and how this process can go awry in humans. Preclinical reviews also within this issue describe how adolescents have prolonged extinction periods to maximize learning about their environment (Baker et al.), whereas Schulz and Sisk focus on the importance of puberty and how it interacts with stress (Romeo). Caballero and Tseng then set the stage of describing the neural circuitry that is often central to these changes and psychopathology. Factors that affect the mis-wiring of the brain for illness, including prenatal exposure to anti-mitotic agents (Gomes et al.) and early life stress and inflammation (Schwarz and Brenhouse), are included as examples of how exposure to early adversity manifests. These reviews are synthesized and show how information from the maturational stages that precede or occur during adolescence is likely to hold the key towards optimizing development to produce an adolescent and adult that is resilient and well adapted to their environment.
journal_name
Neurosci Biobehav Revjournal_title
Neuroscience and biobehavioral reviewsauthors
Andersen SLdoi
10.1016/j.neubiorev.2016.07.012subject
Has Abstractpub_date
2016-11-01 00:00:00pages
329-333eissn
0149-7634issn
1873-7528pii
S0149-7634(16)30301-3journal_volume
70pub_type
杂志文章abstract：:Chronic pain and anxiety can be debilitating disorders and are often comorbid. There is significant overlap in the neural circuitry of pain and anxiety. Current treatments for these disorders are often ineffective and have negative side-effects, making further research into pain and anxiety circuitry crucial. The tech...
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journal_title：Neuroscience and biobehavioral reviews
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journal_title：Neuroscience and biobehavioral reviews
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pub_type： 杂志文章,meta分析,评审
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,meta分析
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journal_title：Neuroscience and biobehavioral reviews
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,meta分析,评审
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更新日期：2014-06-01 00:00:00
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pub_type： 杂志文章
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journal_title：Neuroscience and biobehavioral reviews
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journal_title：Neuroscience and biobehavioral reviews
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pub_type： 杂志文章,评审
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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journal_title：Neuroscience and biobehavioral reviews
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journal_title：Neuroscience and biobehavioral reviews
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pub_type： 杂志文章,评审
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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更新日期：2020-10-17 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/0149-7634(95)00055-0
更新日期：1996-10-01 00:00:00
abstract：:The prefrontal cortex (PFC) mediates a range of higher order 'executive functions' that subserve the selection and processing of information in such a way that behavior can be planned, controlled and directed according to shifting environmental demands. Impairment of executive functions typifies many forms of psychopa...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2008.11.005
更新日期：2009-06-01 00:00:00
abstract：:An increasing number of human electroencephalography (EEG) studies examining the earliest component of the visual evoked potential, the so-called C1, have cast doubts on the previously prevalent notion that this component is impermeable to top-down effects. This article reviews the original studies that (i) described ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/j.neubiorev.2010.12.011
更新日期：2011-04-01 00:00:00
