Supernatant hemoglobin determinations after prolonged blood storage.

abstract：:We evaluated an immunoradiometric assay for serum TSH (IRMA-TSH) and compared it with established indices of thyroid function in 208 patients with either frank thyroid disease, conditions of abnormal thyroxine protein binding, or conditions which are known to produce discordant thyroid results, viz. pregnancy or estro...

journal_title：Pathology

authors： McLellan GH,Riley WJ,Summers MB,Sudholz P,Hickman PE

更新日期：1987-07-01 00:00:00

abstract：:Decreased neutrophil alkaline phosphatase (NAP) synthesis is a classical feature of Philadelphia (Ph) positive chronic phase chronic myeloid leukemia (CML). Whether this aberration is an integral leukemic property of the cell or results from mediation by other factors is unclear. During alpha-interferon (alpha-IFN) ba...

journal_title：Pathology

authors： Taylor DL,Kerwick AM,Elliott SL,Rodwell RL,Wright SJ,Marlton PV,Veleba AR,Taylor KM

更新日期：1993-10-01 00:00:00

abstract：:HLA-B27 is a risk marker for ankylosing spondylitis and other associated seronegative spondyloarthropathies. We compared three methods of HLA-B*27 typing in a New South Wales (NSW) population: flow cytometry, rs4349859 single nucleotide polymorphism (SNP) detection assay, and allele-specific real-time polymerase chain...

journal_title：Pathology

authors： Jang HS,Proos A,Koe L,Anderson J,Fulton R,Fernando SL

更新日期：2020-02-01 00:00:00

abstract：:E-cadherin mediated intercellular adhesion is regulated by a family of cytoplasmic proteins that include alpha-, beta- and gamma-catenin and p120cas. Changes in expression of E-cadherin are believed to be an early event in melanoma development. Recent studies have also drawn attention to the over-expression of beta-ca...

journal_title：Pathology

authors： Zhang XD,Hersey P

更新日期：1999-08-01 00:00:00

abstract：:This review will focus on the molecular biology of lymphoproliferative disorders with emphasis on lymphomas. The spectrum of known recurrent gene rearrangements found in lymphomas will be outlined and their relevance to diagnosis and subclassification of disease will be discussed. Finally, a survey of the current tren...

journal_title：Pathology

authors： Catalano A,Iland H

更新日期：2005-12-01 00:00:00

abstract：:Micropapillary carcinoma of the colon and rectum is associated with an adverse prognosis. This tumour type displays reverse polarity of the tumour cells and is stated to be characterised by an inside-out epithelial membrane antigen (EMA)/MUC1 staining. Nine cases of primary colorectal carcinoma and one omental metasta...

journal_title：Pathology

authors： Cserni G

更新日期：2014-10-01 00:00:00

abstract：:A 59 yr old male presented with abdominal pain and jaundice. CT scan showed a tumor in the pancreas with secondaries in the liver, peri-pancreatic lymph nodes, vertebral bone marrow and subcutaneous tissue of the neck together with a cervical lymph node. The patient died after 2 wks and autopsy revealed complete repla...

journal_title：Pathology

authors： Chetty R,Clark SP,Pitson GA

更新日期：1993-07-01 00:00:00

abstract：:Deregulation of the receptors of TNF-related apoptosis inducing ligand (TRAIL) has been reported in various cancers. In an effort to define the role of these receptors we profiled their expression in gallbladder cancer (GBC) and explored their clinical significance. Expression of TRAIL receptors' mRNA in GBC was analy...

journal_title：Pathology

authors： Singh D,Prasad CB,Biswas D,Tewari M,Kar AG,Ansari MA,Singh S,Narayan G

更新日期：2020-04-01 00:00:00

abstract：:The performance of the Hemalog D on routine blood samples from patients was assessed over a 6 wk period, 500 samples being studied in detail. The performance of the Hematrak was assessed on 85 routine blood samples. It was found that in our hospital population at least 58% of blood samples counted by the Hemalog D wou...

journal_title：Pathology

authors： Bain BJ,Scott D,Scott TJ

更新日期：1980-01-01 00:00:00

abstract：:We report here on the usefulness of the 14C-serotonin release assay for the laboratory confirmation of the clinical diagnosis of heparin-induced thrombocytopenia syndrome (HITS). Over the past 3 yrs, some 140 individual serum samples have been tested in our laboratory for heparin-associated anti-platelet activity ('he...

journal_title：Pathology

authors： Favaloro EJ,Bernal-Hoyos E,Exner T,Koutts J

更新日期：1992-07-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is currently regarded as a myeloid neoplasm, with remarkably broad clinical spectrum, ranging from isolated skin or bone lesions to a disseminated disease that can involve nearly any organ. LCH is generally regarded as a sporadic disease that occurs predominantly in the paediatric p...

journal_title：Pathology

authors： El Demellawy D,Young JL,de Nanassy J,Chernetsova E,Nasr A

更新日期：2015-06-01 00:00:00

abstract：:Gram negative anaerobic organisms are important pathogens in a range of clinical infections, and susceptibility testing is not commonly performed in the microbiology laboratory. We performed anaerobic susceptibility testing on 70 clinically relevant Gram negative anaerobes isolated from routine cultures in a busy diag...

journal_title：Pathology

authors： Hughes C,Ashhurst-Smith C,Ferguson JK

更新日期：2018-06-01 00:00:00

abstract：:Recently developed antibodies against uroplakin II and ΔNp63 (p40) show utility in diagnosing primary bladder urothelial carcinoma, although application in metastatic bladder cancer and patient outcomes has been less well defined. We evaluated these antibodies by immunostain intensity and H-score, in conjunction with ...

journal_title：Pathology

authors： Leivo MZ,Elson PJ,Tacha DE,Delahunt B,Hansel DE

更新日期：2016-10-01 00:00:00

abstract：:A patient with cerebral strokes had a cardiac tumour excised. Histologically, it was an infarcted myxoma with features of a Gamna body. Findings are compared with other cardiac Gamna bodies reported in the literature. Most probably represent unusual degenerative changes in a myxoma. ...

journal_title：Pathology

authors： Coard KC,Silver MD

更新日期：1984-10-01 00:00:00

abstract：:Semen analysis is the most important laboratory investigation for men when assessing the infertile couple. Advances in in vitro fertilisation (IVF) techniques, particularly intracytoplasmic sperm injection (ICSI) involving the direct injection of a single spermatozoon into an egg, have not diminished the role of semen...

journal_title：Pathology

authors： McLachlan RI,Baker HW,Clarke GN,Harrison KL,Matson PL,Holden CA,de Kretser DM,Andrology Australia Australian Centre of Excellence in Male Reproductive Health.,Fertility Society of Australia Scientists in Reproductive Technology Subcommit

更新日期：2003-02-01 00:00:00

abstract：AIMS:Mounting evidence indicates that deregulation of apoptosis is involved in the mechanisms of cancer development. Bax-interacting factor-1 (Bif-1) interacts with both Bax and Bak that are crucial for the intrinsic apoptosis signalling. Functionally, loss of Bif-1 expression has been proven to enhance tumorigenesis. ...

journal_title：Pathology

authors： Kim SY,Oh YL,Kim KM,Jeong EG,Kim MS,Yoo NJ,Lee SH

更新日期：2008-10-01 00:00:00

abstract：AIMS:We aimed to evaluate the effects of caffeic acid phenethyl ester (CAPE) on lithium (Li)-induced lung toxicity. METHODS:Twenty-two adult male Wistar albino rats weighing between 280 and 300 g were used. The rats were randomly divided into three groups: control, Li and Li+CAPE groups. Li and CAPE were co-administer...

journal_title：Pathology

authors： Sahin O,Sulak O,Yavuz Y,Uz E,Eren I,Ramazan Yilmaz H,Malas MA,Altuntas I,Songur A

更新日期：2006-02-01 00:00:00

abstract：AIM:1) To determine the prevalence of hepatitis B in Sydney autopsies and 2) to determine the relationship between seroprevalence, hepatitis B risk factors and histological changes in the liver. METHODS:One hundred autopsy subjects were studied for evidence of past or present hepatitis B infection, using RIA to detect...

journal_title：Pathology

authors： Ashwell MJ,Cossart YE

更新日期：1995-01-01 00:00:00

abstract：:The results of semi-solid cultures of fresh biopsy material from 86 primary human melanomas are reported. Detailed histological assessments by Professor McGovern were available for 80 of the 86 melanomas, and these were compared with the growth characteristics of each specimen. Significant correlations were found betw...

journal_title：Pathology

authors： Vincent PC,Joyce RM,Croaker G,Young GA,Milton GW,McCarthy WH

更新日期：1985-04-01 00:00:00

abstract：AIMS:The increasing importance of cardiac disease has generated an interest in improved screening strategies regarding preclinical cardiac abnormalities and employing measurement of circulating biomarkers. This review focuses on the utility of the B-type natriuretic peptides (NP) and the cardiac troponins (cTns) for th...

journal_title：Pathology

authors： Eggers KM,Venge P

更新日期：2012-02-01 00:00:00

abstract：:Sera from 82 patients with acute or chronic hepatitis and 40 chronic carriers of hepatitis B were examined by ELISA and immunoblotting for reactivity with the glycolytic enzyme aldolase. The results of the ELISA tests, expressed as a percentage of a positive control, were compared to those obtained with sera from 39 p...

journal_title：Pathology

authors： Brown C,Toh BH,Pedersen JS,Clarke FM,Mackay IR,Gust I

更新日期：1987-10-01 00:00:00

abstract：AIMS:It is currently accepted that primary ovarian tumours rarely, if ever, give rise to mucinous ascites/pseudomyxoma peritonei (PMP) which most commonly results from the intra-abdominal spread of an appendiceal mucinous neoplasm. However, primary ovarian mucinous tumours of appendiceal type arising within mature cyst...

journal_title：Pathology

authors： Stewart CJ,Tsukamoto T,Cooke B,Leung YC,Hammond IG

更新日期：2006-12-01 00:00:00

abstract：:Recent controversies both in Australia and overseas have focused public attention on autopsy practice. It has become apparent that there is an increasing expectation amongst the public for more detailed information concerning autopsy procedures and, in particular, tissue retention. This article attempts to review the ...

journal_title：Pathology

authors： Lynch MJ

更新日期：2002-02-01 00:00:00

abstract：:Isolation of the new pandemic virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for diagnostic and research purposes including assessment of novel therapeutics. Several primary and continuous cell lines are currently used, and new organoid and engineered cell lines are being developed for...

journal_title：Pathology

authors： Stelzer-Braid S,Walker GJ,Aggarwal A,Isaacs SR,Yeang M,Naing Z,Ospina Stella A,Turville SG,Rawlinson WD

更新日期：2020-12-01 00:00:00

abstract：:The aim of the present study is to describe the histological and mutational characteristics of a series of both large and small bowel adenocarcinomas in patients with Crohn's disease from a tertiary referral centre of inflammatory bowel disease. Bowel adenocarcinoma was diagnosed in 11 (1.7%) of 660 consecutive patien...

journal_title：Pathology

authors： Malvi D,Vasuri F,Mattioli B,Gruppioni E,Fiorentino M,Gionchetti P,Grigioni WF,Poggioli G,D'Errico-Grigioni A

更新日期：2014-08-01 00:00:00

abstract：:The current public health emergency surrounding the COVID-19 pandemic, that is the illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in thousands of cases in Australia since 25 January 2020 when the first case was diagnosed. This emerging virus presents particular hazards to ...

journal_title：Pathology

authors： Kaufer AM,Theis T,Lau KA,Gray JL,Rawlinson WD

更新日期：2020-12-01 00:00:00

abstract：:The estimation of plasma alanine aminotransferase (ALT) has been proposed as a surrogate test to identify potential non-A, non-B hepatitis carriers in blood donor populations. This report describes an ALT screening procedure which uses wells of microtitration trays as reactant vessels. The method utilizes a rate readi...

journal_title：Pathology

authors： Hyland CA,Douglas R,Mazzocchi R,Young IF

更新日期：1988-07-01 00:00:00

abstract：:Rare tumours are a heterogeneous group of conditions that encompass benign to malignant lesions both of stromal and epithelial origin. Here some of these tumours are described, in which the authors have most familiarity. An outline of medullary carcinoma is also presented. ...

journal_title：Pathology

authors： Foschini MP,Eusebi V

更新日期：2009-01-01 00:00:00

abstract：:Pseudomonas aeruginosa is a common pathogen causing nosocomial infection. In particular, bloodstream infection (BSI) is associated with a high rate of morbidity and mortality. Ceftolozane/tazobactam is a new β-lactam/β-lactamase antimicrobial with activity against P. aeruginosa as well as multidrug resistant (MDR) Gra...

journal_title：Pathology

authors： Henderson A,Tan E,McCarthy KL,Paterson DL

更新日期：2018-12-01 00:00:00

abstract：:The recent upsurge in the association of congenital neurological disorders and infection by the Zika virus (ZIKV) has resulted in increased research focus on the biology of this flavivirus. Studies in animal models indicate that ZIKV can breach the placental barrier and selectively infect and deplete neuroprogenitor c...

journal_title：Pathology

authors： Gharbaran R,Somenarain L

更新日期：2017-12-01 00:00:00