Effect of storage processes on the bacterial growth-inhibiting activity of human breast milk.

Abstract:

:Human breast milk samples were collected from lactating mothers, and aliquots were maintained at room temperature, frozen, and pasteurized. Samples were inoculated with 10 to 50 colony-forming units per milliliter (cfu/ml) of Escherichia coli or group B streptococcus, and incubated at 37 C. Quantitative growth was measured at eight and 24 hours. No inhibitory activity was demonstrated by control broth, commercial formula, and pasteurized breast milk, which had a rapid logarithmic growth to a maximum of 10(8) to 10(9) cfu/ml at 24 hours. Compared with these controls, fresh breast milk, fresh frozen breast milk, and breast milk frozen for 21 days demonstrated a significant inhibition of bacteria growth. A trend toward gradual loss of inhibiting activity was noted with prolonged freezing of breast milk. Although freezing may quantitativly decrease the amount of some breast milk host-defense factors, it cannot be assumed that comparable functional reductions will necessarily result.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Hernandez J,Lemons P,Lemons J,Todd J

subject

Has Abstract

pub_date

1979-04-01 00:00:00

pages

597-601

issue

4

eissn

0031-4005

issn

1098-4275

journal_volume

63

pub_type

杂志文章
  • Pharmacologic compliance with antibiotic therapy for acute otitis media: influence on subsequent middle ear effusion.

    abstract::The frequency of otitis media with effusion (serous otitis media, secretory otitis media) detected after conventional antibiotic treatment of acute otitis media is approximately 50%. The relationship between pharmacologic compliance and the frequency of otitis media with effusion was studied. A Micrococcus lutea bioin...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Schwartz RH,Rodriquez WJ,Grundfast KM

    更新日期:1981-11-01 00:00:00

  • Fatal and nonfatal farm injuries to children and adolescents in the United States.

    abstract::Agriculture is the second most dangerous occupation in the United States, and unlike other occupations, children make up a significant portion of the work force. This study presents national data on the morbidity and mortality due to farm injuries to children and adolescents less than or equal to 19 years of age. Data...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Rivara FP

    更新日期:1985-10-01 00:00:00

  • Enterovirus 71 infection: report of an outbreak with two cases of paralysis and a review of the literature.

    abstract::Enterovirus 71 (E-71) infection was first reported in 19745 in the United States; subsequent outbreaks were reported in worldwide distribution. In the summer of 1977, we identified 12 patients, mostly children, with E-71 infection. The striking feature of this outbreak is the occurrence of two cases with polio-like pa...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Chonmaitree T,Menegus MA,Schervish-Swierkosz EM,Schwalenstocker E

    更新日期:1981-04-01 00:00:00

  • Cerebral oxygenation in preterm infants.

    abstract:BACKGROUND AND OBJECTIVE:Prone sleeping is a major risk factor for sudden infant death syndrome (SIDS) and preterm infants are at significantly increased risk. In term infants, prone sleeping is associated with reduced mean arterial pressure (MAP) and cerebral tissue oxygenation index (TOI). However, little is known ab...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2014-0773

    authors: Fyfe KL,Yiallourou SR,Wong FY,Odoi A,Walker AM,Horne RS

    更新日期:2014-09-01 00:00:00

  • Fat-soluble vitamin concentrations in hypercholesterolemic children treated with colestipol.

    abstract::In summary: (1) Colestipol therapy plus diet reduced total cholesterol 19 +/- 3% in 11 hypercholesterolemic children after two months and 13 +/- 5% after two years in five children. (2) Diet therapy did not significantly reduce serum concentration of any of the fat-soluble vitamins or folate. (3) During 24 months of c...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Schwarz KB,Goldstein PD,Witztum JL,Schonfeld G

    更新日期:1980-02-01 00:00:00

  • Massachusetts Metabolic Disorders Screening Program: III. Sarcosinemia.

    abstract::Sarcosinemia has been detected by routine screening of urine for metabolic and transport disorders in Massachusetts. Three infants who had sarcosinemia were detected through the neonatal urine specimen, an observed incidence of 1:350,000. A fourth child had sarcosinemia detected through family screening after his brot...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Levy HL,Coulombe JT,Benjamin R

    更新日期:1984-10-01 00:00:00

  • Research Gaps in Primary Pediatric Hypertension.

    abstract::Hypertension affects >40% of the US population and is a major contributor to cardiovascular-related morbidity and mortality. Although less common among children and adolescents, hypertension affects 1% to 5% of all youth. The 2017 Clinical Practice Guideline for the Diagnosis and Management of High Blood Pressure in C...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2018-3517

    authors: Taylor-Zapata P,Baker-Smith CM,Burckart G,Daniels SR,Flynn JT,Giacoia G,Green D,Kelly AS,Khurana M,Li JS,Pratt C,Urbina EM,Zajicek A

    更新日期:2019-05-01 00:00:00

  • Premedication for nonemergent neonatal intubations: a randomized, controlled trial comparing atropine and fentanyl to atropine, fentanyl, and mivacurium.

    abstract:OBJECTIVE:The purpose of this work was to investigate whether using a muscle relaxant would improve intubation conditions in infants, thereby decreasing the incidence and duration of hypoxia and time and number of attempts needed to successfully complete the intubation procedure. PATIENTS/METHODS:This was a prospectiv...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2006-0590

    authors: Roberts KD,Leone TA,Edwards WH,Rich WD,Finer NN

    更新日期:2006-10-01 00:00:00

  • Improving the quality of discharge communication with an educational intervention.

    abstract:BACKGROUND:Communication between hospital providers and primary care physicians at the time of hospital discharge is necessary for optimal patient care and safety. Content of the inpatient discharge summary (DS) is not uniformly addressed by residency programs. OBJECTIVE:To improve DSs quality through a brief educatio...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-0884

    authors: Key-Solle M,Paulk E,Bradford K,Skinner AC,Lewis MC,Shomaker K

    更新日期:2010-10-01 00:00:00

  • Infection prevention and control in pediatric ambulatory settings.

    abstract::Since the American Academy of Pediatrics published a statement titled "Infection Control in Physicians' Offices" (Pediatrics. 2000;105[6]:1361-1369), there have been significant changes that prompted this updated statement. Infection prevention and control is an integral part of pediatric practice in ambulatory medica...

    journal_title:Pediatrics

    pub_type: 杂志文章,实务指引

    doi:10.1542/peds.2007-1734

    authors: American Academy of Pediatrics Committee on Infectious Diseases.

    更新日期:2007-09-01 00:00:00

  • Athletic participation by children and adolescents who have systemic hypertension. American Academy of Pediatrics Committee on Sports Medicine and Fitness.

    abstract::Children and adolescents who have systemic hypertension may be at risk for complications when exercise causes their blood pressures to rise even higher. The purpose of this statement is to make recommendations concerning the athletic participation of individuals with hypertension using the 26th Bethesda Conference on ...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章,实务指引

    doi:10.1542/peds.99.4.637

    authors:

    更新日期:1997-04-01 00:00:00

  • Children in alcohol-related motor vehicle crashes.

    abstract::Review of North Carolina traffic crash data revealed that alcohol use, although associated with 7.9% of motor vehicle crashes involving children, accounted for 15.4% of the motor vehicle-related deaths and 10.4% of the injuries. The largest proportion of these deaths were child passengers in a vehicle in which the dri...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Margolis LH,Kotch J,Lacey JH

    更新日期:1986-06-01 00:00:00

  • Pediatrician Perspectives on Feasibility and Acceptability of the MOCA-Peds 2017 Pilot.

    abstract:BACKGROUND AND OBJECTIVES:The American Board of Pediatrics (ABP) certifies that general and subspecialty pediatricians meet standards of excellence established by their peers, immediately after training and over the course of their careers (ie, Maintenance of Certification [MOC]). In 2015-2016, the ABP developed the Ma...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-2303

    authors: Leslie LK,Turner AL,Smith AC,Dounoucos V,Olmsted MG,Althouse L

    更新日期:2019-12-01 00:00:00

  • Use of bacterial antigen detection in the diagnosis of pediatric lower respiratory tract infections.

    abstract::Two immunochemical methods were used to identify Haemophilus influenzae and Streptococcus pneumoniae capsular antigens in the urine and serum of 162 children with acute lower respiratory tract infection. These methods were compared with standard bacterial blood culture. Viral and mycoplasma cultures of respiratory sec...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Ramsey BW,Marcuse EK,Foy HM,Cooney MK,Allan I,Brewer D,Smith AL

    更新日期:1986-07-01 00:00:00

  • A scoring system for early prognostic assessment after neonatal seizures.

    abstract:OBJECTIVE:The aim of this study was to devise a scoring system that could aid in predicting neurologic outcome at the onset of neonatal seizures. METHODS:A total of 106 newborns who had neonatal seizures and were consecutively admitted to the NICU of the University of Parma from January 1999 through December 2004 were...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-2087

    authors: Pisani F,Sisti L,Seri S

    更新日期:2009-10-01 00:00:00

  • Detection of Kingella kingae osteoarticular infections in children by oropharyngeal swab PCR.

    abstract:OBJECTIVE:The purpose of this study was to investigate if oropharyngeal swab polymerase chain reaction (PCR) could predict osteoarticular infection (OAI) due to Kingella kingae in young children. METHODS:One hundred twenty-three consecutive children aged 6 to 48 months presenting with atraumatic osteoarticular complai...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-0810

    authors: Ceroni D,Dubois-Ferriere V,Cherkaoui A,Gesuele R,Combescure C,Lamah L,Manzano S,Hibbs J,Schrenzel J

    更新日期:2013-01-01 00:00:00

  • Hospital-acquired urinary tract infection.

    abstract::From 16,534 admissions, 60 patients, 4 days to 15 years of age, with one or more hospital-acquired urinary tract infections were identified during a 5-year period by a prospective surveillance system. The patient charts were subsequently reviewed to characterize the population at risk for such infections and to descri...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Lohr JA,Donowitz LG,Sadler JE 3rd

    更新日期:1989-02-01 00:00:00

  • Goat's milk as a substitute for cow's milk in undernourished children: a randomized double-blind clinical trial.

    abstract:OBJECTIVE:This paper compares the effects of goat's milk and cow's milk on weight gain and fat absorption, in children with overt malnutrition. METHODS:Thirty hospitalized malnourished children aged from 1 to 5 years were included in a randomized double-blind trial. The children were fed either goat or cow's milk with...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Razafindrakoto O,Ravelomanana N,Rasolofo A,Rakotoarimanana RD,Gourgue P,Coquin P,Briend A,Desjeux JF

    更新日期:1994-07-01 00:00:00

  • Sleep deprivation for pediatric sedated procedures: not worth the effort.

    abstract:OBJECTIVE:Sleep deprivation is commonly used to enhance the effectiveness of pediatric sedation and to decrease sedation failures. We reviewed our sedation database to evaluate the efficacy of sleep deprivation. METHODS:The entire pediatric sedation unit database (n = 5640) was reviewed retrospectively. Patients witho...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.113.5.1204

    authors: Shields CH,Johnson S,Knoll J,Chess C,Goldberg D,Creamer K

    更新日期:2004-05-01 00:00:00

  • Obesity rather than severity of sleep-disordered breathing as the major determinant of insulin resistance and altered lipidemia in snoring children.

    abstract:OBJECTIVE:Sleep-disordered breathing (SDB) is associated with insulin resistance and dyslipidemia in adults and in obese children. However, the prevalence of such metabolic abnormalities among snoring children is unknown. This study was done to prospectively assess the relative contribution of SDB and obesity to metabo...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-2527

    authors: Tauman R,O'Brien LM,Ivanenko A,Gozal D

    更新日期:2005-07-01 00:00:00

  • Growth and fat-free mass gain in preterm infants after discharge: a randomized controlled trial.

    abstract:OBJECTIVE:To investigate whether the consumption of a nutrient-enriched formula after hospital discharge determines different growth and weight gain composition in preterm infants according to intra- and extrauterine growth pattern. METHODS:Two hundred seven preterm infants were randomized at term-corrected age to rec...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2012-1193

    authors: Roggero P,Giannì ML,Amato O,Liotto N,Morlacchi L,Orsi A,Piemontese P,Taroni F,Morniroli D,Bracco B,Mosca F

    更新日期:2012-11-01 00:00:00

  • Effects of nurse home visiting on maternal and child functioning: age-9 follow-up of a randomized trial.

    abstract:OBJECTIVE:Our goal was to test the effect of prenatal and infancy home visits by nurses on mothers' fertility and children's functioning 7 years after the program ended at child age 2. METHODS:We conducted a randomized, controlled trial in a public system of obstetric and pediatric care. A total of 743 primarily black...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2006-2111

    authors: Olds DL,Kitzman H,Hanks C,Cole R,Anson E,Sidora-Arcoleo K,Luckey DW,Henderson CR Jr,Holmberg J,Tutt RA,Stevenson AJ,Bondy J

    更新日期:2007-10-01 00:00:00

  • Preoperative Blood Transfusions and Morbidity in Neonates Undergoing Surgery.

    abstract:BACKGROUND:Blood transfusions in the neonatal patient population are common, but there are no established guidelines regarding transfusion thresholds. Little is known about postoperative outcomes in neonates who receive preoperative blood transfusions (PBTs). METHODS:Using the American College of Surgeons National Sur...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-3718

    authors: Dukleska K,Vinocur CD,Brenn BR,Lim DJ,Keith SW,Dirnberger DR,Berman L

    更新日期:2020-11-01 00:00:00

  • Detection of human immunodeficiency virus type 1 (HIV-1) DNA and p24 antigen in breast milk of HIV-1-infected Ugandan women and vertical transmission.

    abstract:OBJECTIVE:To determine the correlation between the detection of human immunodeficiency virus type 1 (HIV-1) in breast milk, the duration of breastfeeding, and vertical transmission of HIV-1 infection in Ugandan women. METHODS:A prospective study of HIV-1 infection in pregnant Ugandan women and their infants has been o...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Guay LA,Hom DL,Mmiro F,Piwowar EM,Kabengera S,Parsons J,Ndugwa C,Marum L,Olness K,Kataaha P,Jackson JB

    更新日期:1996-09-01 00:00:00

  • Cost-effectiveness analysis of bicycle helmet subsidies in a defined population.

    abstract:OBJECTIVE:To examine the potential effects of bicycle safety helmet cost subsidy on bicycle head injury rates and costs. DESIGN:Using empiric data on the incidence and costs of bicycle injuries to children, we examined the hypothetical effects of various bicycle helmet subsidies in a cost-effectiveness analysis. A hyp...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Thompson RS,Thompson DC,Rivara FP,Salazar AA

    更新日期:1993-05-01 00:00:00

  • Mortality risk in children with epilepsy: the Dutch study of epilepsy in childhood.

    abstract:OBJECTIVE:Long-term follow-up studies of patients with epilepsy have revealed an increased mortality risk compared with the general population. Mortality of children who have epilepsy in modern times is as yet unknown. Therefore, the objective of this study was to determine mortality of children who have epilepsy in co...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.107.6.1259

    authors: Callenbach PM,Westendorp RG,Geerts AT,Arts WF,Peeters EA,van Donselaar CA,Peters AC,Stroink H,Brouwer OF

    更新日期:2001-06-01 00:00:00

  • Characteristics of pediatric and adolescent patients attending a naturopathic college clinic in Canada.

    abstract:OBJECTIVES:The use of complementary and alternative medicine (CAM) has grown substantially in North America and has drawn the attention of conventional-medicine practitioners. Conventional-medicine practitioners have expressed concern about the potential for unregulated CAM therapies to cause harm, the sometimes-uncert...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1901

    authors: Wilson K,Busse JW,Gilchrist A,Vohra S,Boon H,Mills E

    更新日期:2005-03-01 00:00:00

  • The national immunization program of The Netherlands.

    abstract::After a brief explanation of the immunization policy in the Netherlands, the national immunization program is described, with special attention given to coupling of the municipal population records with a computerized database of individual immunization records at the provincial level. The Dutch program achieves cover...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Verbrugge HP

    更新日期:1990-12-01 00:00:00

  • Successive multisite peripheral nerve catheters for treatment of complex regional pain syndrome type I.

    abstract::Complex regional pain syndrome (CRPS) type I is a painful and disabling syndrome that is accompanied by physical changes in the affected extremity. It generally occurs after trauma, manifesting as pain that is out of proportion to the inciting event. Treatment of the disorder is difficult, with many patients being ref...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-3779

    authors: Martin DP,Bhalla T,Rehman S,Tobias JD

    更新日期:2013-01-01 00:00:00

  • Mitomycin C test for diagnostic differentiation of idiopathic aplastic anemia and Fanconi anemia.

    abstract::A cytogenetic test was developed to enable the diagnostic differentiation between Fanconi anemia and the group of disorders classified as "idiopathic" aplastic anemia. The method is based on the effect of the bifunctional alkylating agent mitomycin C (MMC) on chromosomes of peripheral lymphocytes in culture 92 to 96 h...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Cervenka J,Arthur D,Yasis C

    更新日期:1981-01-01 00:00:00