Abstract:
BACKGROUND:Blood transfusions in the neonatal patient population are common, but there are no established guidelines regarding transfusion thresholds. Little is known about postoperative outcomes in neonates who receive preoperative blood transfusions (PBTs). METHODS:Using the American College of Surgeons National Surgical Quality Improvement Program-Pediatric Participant Use Data Files from 2012 to 2015, we identified all neonates who underwent surgery. Mortality and composite morbidity (defined as any postoperative complication) in neonates who received a PBT within 48 hours of surgery were compared with that in neonates who did not receive a transfusion. RESULTS:A total of 12 184 neonates were identified, of whom 1209 (9.9%) received a PBT. Neonates who received a PBT had higher rates of preoperative comorbidities and worse postoperative outcomes when compared with those who did not receive a transfusion (composite morbidity: 46.2% vs 16.2%; P < .01). On multivariable regression analysis, PBTs were independently associated with increased 30-day morbidity (odds ratio [OR] = 1.90; 95% confidence interval [CI]: 1.63-2.22; P < .01) and mortality (OR = 1.98; 95% CI: 1.55-2.55; P < .01). In a propensity score-matched analysis, PBTs continued to be associated with increased 30-day morbidity (OR = 1.53; 95% CI: 1.29-1.81; P < .01) and mortality (OR = 1.58; 95% CI: 1.24-2.01; P = .01). CONCLUSIONS:In a propensity score-matched model, PBTs are independently associated with increased morbidity and mortality in neonates who undergo surgery. Prospective data are needed to better understand the potential effects of a red blood cell transfusion in this patient population.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Dukleska K,Vinocur CD,Brenn BR,Lim DJ,Keith SW,Dirnberger DR,Berman Ldoi
10.1542/peds.2019-3718subject
Has Abstractpub_date
2020-11-01 00:00:00issue
5eissn
0031-4005issn
1098-4275pii
peds.2019-3718journal_volume
146pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract::The movement of young adults with special health care needs from pediatric-oriented care to adult-oriented care has been a growing concern in the health care literature over the past 20 years. This article reviews the development and evaluation of health care transition policy over that period of time. These health ca...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:Circumstances surrounding parental availability and decision-making were examined in the setting of a research protocol involving newborn screening (NBS) for fragile X syndrome, in which the institutional review board (IRB) had determined that consent (permission) was required from both parents. METHODS:A su...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-1278
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Recommended durations of observation after anaphylaxis have been widely variable, with many ranging from 4 to 24 hours. Prolonged durations often prompt admission for ongoing observation. METHODS:In a multidisciplinary quality improvement initiative, we revised our emergency department (ED) anaphylaxis clin...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-1616
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:To assess the effects of electronic health record-based clinical decision support (CDS) and physician performance feedback on adherence to guidelines for acute otitis media (AOM) and otitis media with effusion (OME). METHODS:We conducted a factorial-design cluster randomized trial with primary care practices...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2012-1988
更新日期:2013-04-01 00:00:00
abstract::An 11-year-old boy had clinical signs of an acute inferior wall myocardial infarction. On echocardiography, a left atrial myxoma was demonstrated. Coronary artery embolization from myxoma was confirmed by selective coronary arteriography. The tumor was removed 12 days after acute coronary embolization. The clinical va...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1979-05-01 00:00:00
abstract:OBJECTIVES:To assess the annual prevalence of physical violence from dating partners among a representative sample of sexually experienced adolescent girls attending US public and private high schools, as well as sexual risk behaviors and pregnancy among this population. DESIGN, SETTING, PARTICIPANTS, AND MEASURES:Fem...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.114.2.e220
更新日期:2004-08-01 00:00:00
abstract::The epidemiology of Helicobacter pylori infection was studied in 245 healthy children (between 3 and 20 years of age) who presented for day surgery at Arkansas Children's Hospital. H pylori infection was identified serologically using an enzyme-linked immunosorbent assay to detect the presence of IgG against the high ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
abstract::Clostridium difficile was isolated from the feces of two infants who had developed watery diarrhea with blood-tinged stain. One child suffered from diarrhea after five days of parenteral oxacillin therapy; the diarrhea subsided within three days of cessation of therapy. The other infant developed diarrhea following fo...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract::The opportunity to improve health care using existing scientific knowledge is immense. Much is known that is not being used in routine care, leading to a large gap between knowledge and practice. Collaborative improvement models bring health care professionals together to focus on this gap and to accelerate the pace o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between local macroeconomic indicators and physical abuse admission rates to pediatric hospitals over time. METHODS:Retrospective study of children admitted to 38 hospitals in the Pediatric Hospital Information System database. Hospital data were linked to unemployment, mortgage d...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-3755
更新日期:2012-08-01 00:00:00
abstract::A sample of 90 children with Down's syndrome were measured for recumbent length and weight from birth to age 36 months at the Children's Hospital Medical Center in Boston. At birth, means for both length and weight were reduced by about 0.5 SDs from the control group means. By 36 months, mean recumbent length was grea...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract::Immersion in water has been suggested as a beneficial alternative for labor, delivery, or both and over the past decades has gained popularity in many parts of the world. Immersion in water during the first stage of labor may be associated with decreased pain or use of anesthesia and decreased duration of labor. Howev...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-3794
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of home intervention with drug-abusing women on parenting behavior and attitudes, and on children's development. DESIGN:A randomized, clinical trial of 60 drug-abusing women recruited prenatally and randomized into an intervention (n = 31) or comparison (n = 29) group. There were no ...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-10-01 00:00:00
abstract:OBJECTIVE:Previous studies demonstrate significant associations between dating-violence victimization and sexual risk behaviors among adolescent girls; however, a relationship between dating violence and actual sexually transmitted disease (STD)/HIV testing and diagnosis has yet to be investigated among a representativ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-0194
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVES:Inadequate sleep during infancy is associated with adverse outcomes for infants and families. We sought to improve sleep behaviors and duration through a responsive parenting (RP) intervention designed for obesity prevention. METHODS:The Intervention Nurses Start Infants Growing on Healthy Trajectories (INS...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2016-0762
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Parental smoking has been associated with increased rates of sudden infant death syndrome, low birth weight, otitis media, asthma, and decreased lung growth. No prior parent surveys have assessed national rates of screening and counseling for parental tobacco use in the context of their child's visit to prim...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.112.5.1146
更新日期:2003-11-01 00:00:00
abstract::Nonfamilial cardiomyopathies in childhood have been only sporadically ascribed to endocrine disorders. We report on a 4-month-old male infant presenting with Cushing's syndrome associated with excessive body weight (8.9 kg; >97th percentile) and features of virilization (Tanner stage 2 for pubic hair development). Abd...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-2692
更新日期:2013-08-01 00:00:00
abstract:INTRODUCTION:Renovascular disease accounts for the vast majority of cases of infantile hypertension with complications resulting from umbilical arterial catheterization predominating in the neonatal period and fibrodysplastic lesions of the renal artery predominating outside the neonatal period. We report a previously ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.103.5.e66
更新日期:1999-05-01 00:00:00
abstract::Venipuncture and intravenous cannulation are among the most common and widespread medical procedures performed on children today. Therefore, effective treatment of venous access pain can benefit from an integrated systems approach that enlists multiple players in the health care system. By using case studies that anal...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2008-1055i
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Maintaining adequate organ blood flow is the target of vasopressor treatment, but the impact of these measures on cerebral perfusion has not yet been evaluated systematically in a randomized, blinded, clinical trial. OBJECTIVES:To explore the effects on brain hemodynamics of 2 different inotropic agents use...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1542/peds.2004-1396
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVE:To compare early nondrinkers, experimenters, and drinkers on the prevalence of problem behaviors at grades 7 and 12 and at age 23 (N = 6338, 4265, and 3369, respectively). METHODS:Results are based on longitudinal self-report data from individuals who were originally recruited from 30 California and Oregon s...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.111.5.949
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:Our goal was to evaluate the applicability of a "wage-payment" model to inducements for children to participate in research. SUBJECTS AND METHODS:We interviewed 42 children and adolescents between the ages of 4 and 16 years who had diabetes, asthma, seizures, or no chronic medical condition. The interview ex...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-1813
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:Unintended variation in the care of patients with Crohn disease (CD) and ulcerative colitis (UC) may prevent achievement of optimal outcomes. We sought to improve chronic care delivery and outcomes for children with inflammatory bowel disease by using network-based quality improvement methods. METHODS:By us...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2011-1700
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:Siblings and other children who share a home with a physically abused child are thought to be at high risk for abuse, but rates of injury in these contact children are unknown and screening of contacts is highly variable. Our objective was to determine the prevalence of abusive injuries identified by a common...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-0085
更新日期:2012-08-01 00:00:00
abstract::Children who become overweight by age 2 years have significantly greater risks of long-term health problems, and children in low-income communities, where rates of low adult literacy are highest, are at increased risk of developing obesity. The objective of the Greenlight Intervention Study is to assess the effectiven...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2013-3867
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:To examine whether parenting styles or practices were associated with children's television (TV) viewing. METHODS:A total of 431 parent-child dyads (10- to 11-year-old children) from Bristol, United Kingdom, were included. Child and parent TV viewing were self-reported and categorized as <2, 2 to 4, or >4 ho...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-3664
更新日期:2011-09-01 00:00:00
abstract::Sudden infant death syndrome (SIDS) victims were regarded as normal as a matter of definition (Beckwith 1970) until 1952 when Kinney and colleagues argued for elimination of the clause, "unexpected by history." They argued that "not all SIDS victims were normal," and referred to their hypothesis that SIDS results from...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.110.5.e64
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:After licensure of the 7-valent pneumococcal conjugate vaccine (PCV7) in the United States in 2000, the incidence of pediatric pneumococcal meningitis decreased significantly. However, cases continue to occur. It is unknown whether meningitis due to PCV7 and non-PCV7 serotypes causes similar morbidity and mo...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-0621
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:The Parent Report of Children's Abilities-Revised (PARCA-R) is a questionnaire for assessing cognitive and language development in very preterm infants. Given the increased risk of developmental delay in infants born late and moderately preterm (LMPT; 32-36 weeks), this study aimed to validate this questionn...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-0266
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:Ataxia-telangiectasia (AT) is a rare, autosomal recessive neurodegenerative disorder in which the diagnosis is obvious when ataxia and telangiectasia are both present. However, the diagnosis can be made upon the onset of ataxia and before the appearance of telangiectasia if confirmed by laboratory tests. Ear...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.102.1.98
更新日期:1998-07-01 00:00:00