A scoring system for early prognostic assessment after neonatal seizures.

Abstract:

OBJECTIVE:The aim of this study was to devise a scoring system that could aid in predicting neurologic outcome at the onset of neonatal seizures. METHODS:A total of 106 newborns who had neonatal seizures and were consecutively admitted to the NICU of the University of Parma from January 1999 through December 2004 were prospectively followed-up, and neurologic outcome was assessed at 24 months' postconceptional age. We conducted a retrospective analysis on this cohort to identify variables that were significantly related to adverse outcome and to develop a scoring system that could provide early prognostic indications. RESULTS:A total of 70 (66%) of 106 infants had an adverse neurologic outcome. Six variables were identified as the most important independent risk factors for adverse outcome and were used to construct a scoring system: birth weight, Apgar score at 1 minute, neurologic examination at seizure onset, cerebral ultrasound, efficacy of anticonvulsant therapy, and presence of neonatal status epilepticus. Each variable was scored from 0 to 3 to represent the range from "normal" to "severely abnormal." A total composite score was computed by addition of the raw scores of the 6 variables. This score ranged from 0 to 12. A cutoff score of > or =4 provided the greatest sensitivity and specificity. CONCLUSIONS:This scoring system may offer an easy, rapid, and reliable prognostic indicator of neurologic outcome after the onset of neonatal seizures. A final assessment of the validity of this score in routine clinical practice will require independent validation in other centers.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Pisani F,Sisti L,Seri S

doi

10.1542/peds.2008-2087

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

e580-7

issue

4

eissn

0031-4005

issn

1098-4275

pii

peds.2008-2087

journal_volume

124

pub_type

杂志文章
  • Growth and development in a child with resistance to thyroid hormone and ectopic thyroid gland.

    abstract::Resistance to thyroid hormone is an uncommon problem, which has rarely been associated with thyroid dysgenesis. We report a case with both thyroid gland ectopy and resistance to thyroid hormone and, thus, a reduced capacity to produce and respond to thyroid hormone. The patient presented at 2 years of age with develop...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-0634

    authors: Heather N,Hall K,Neas K,Potter H,Wiltshire E

    更新日期:2012-03-01 00:00:00

  • Sexual history documentation in adolescent emergency department patients.

    abstract:OBJECTIVES:To determine the frequency of physician-documented sexual histories in female adolescents who presented to an emergency department (ED) with symptoms suggestive of a sexually transmitted infection (STI). Our secondary objectives were to determine if physician-documented sexual history is associated with incr...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-1775

    authors: Goyal M,McCutcheon M,Hayes K,Mollen C

    更新日期:2011-07-01 00:00:00

  • Severe renal osteodystrophy without elevated serum immunoreactive parathyroid hormone concentrations in hypomagnesemia due to renal magnesium wasting.

    abstract::An 8 1/2-year-old girl presented with a long history of seizures, growth retardation, muscle weakness, gait disturbance, and hearing loss. Her evaluation revealed chronic moderate renal failure (serum creatinine 2.2 mg/dL), severe hypocalcemia (5 mg/dL), hyperphosphatemia (8.1 mg/dL), hypomagnesemia (1.5 mg/dL), incre...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Zelikovic I,Dabbagh S,Friedman AL,Goelzer ML,Chesney RW

    更新日期:1987-03-01 00:00:00

  • Using mass media to reduce adolescent involvement in drug trafficking.

    abstract:OBJECTIVE:Drug trafficking among adolescents is a newly recognized high-risk behavior that seems to be involving large numbers of youths. Strategies to prevent and/or alter this behavior must be developed and evaluated. In view of the high exposure of adolescents to the mass media, interventionists seeking to reduce ad...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Romer D

    更新日期:1994-06-01 00:00:00

  • Epidemiology of juvenile chronic arthritis in southwestern Sweden: a 5-year prospective population study.

    abstract::Previous epidemiological studies of juvenile chronic arthritis (JCA) report divergent results owing to differences in diagnostic criteria, patient retrieval, and study designs. To investigate incidence and prevalence of JCA in a total population, this prospective survey was performed in southwestern Sweden between 198...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gäre BA,Fasth A

    更新日期:1992-12-01 00:00:00

  • Treatment outcomes of overweight children and parents in the medical home.

    abstract:OBJECTIVE:To test in the primary care setting the short- and long-term efficacy of a behavioral intervention that simultaneously targeted an overweight child and parent versus an information control (IC) targeting weight control only in the child. METHODS:Two- to 5-year-old children who had BMI ≥85th percentile and an...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2013-4084

    authors: Quattrin T,Roemmich JN,Paluch R,Yu J,Epstein LH,Ecker MA

    更新日期:2014-08-01 00:00:00

  • Telemedicine for evaluation of retinopathy of prematurity.

    abstract::Retinopathy of prematurity (ROP) remains a significant threat to vision for extremely premature infants despite the availability of therapeutic modalities capable, in most cases, of managing this disorder. It has been shown in many controlled trials that application of therapies at the appropriate time is essential to...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2014-0978

    authors: Fierson WM,Capone A Jr,American Academy of Pediatrics Section on Ophthalmology.,American Academy of Ophthalmology, American Association of Certified Orthoptists.

    更新日期:2015-01-01 00:00:00

  • Children Exposed to Maltreatment: Assessment and the Role of Psychotropic Medication.

    abstract::Pediatricians regularly care for children who have experienced child maltreatment. Child maltreatment is a risk factor for a broad range of mental health problems. Issues specific to child maltreatment make addressing emotional and behavioral challenges among maltreated children difficult. This clinical report focuses...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-3751

    authors: Keeshin B,Forkey HC,Fouras G,MacMillan HL,AMERICAN ACADEMY OF PEDIATRICS, COUNCIL ON CHILD ABUSE AND NEGLECT, COUNCIL ON FOSTER CARE, ADOPTION, AND KINSHIP CARE, AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, COMMITTEE ON CHILD MALTREATMEN

    更新日期:2020-02-01 00:00:00

  • Vaccination and Risk of Childhood IgA Vasculitis.

    abstract:BACKGROUND AND OBJECTIVES:Immunoglobulin A vasculitis (IgAV) might develop after vaccination. However, this potential relationship is essentially based on case reports, and robust pharmaco-epidemiologic data are scarce. We aimed to investigate the effect of vaccination on short-term risk of IgAV in children. METHODS:W...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2018-0841

    authors: Piram M,Gonzalez Chiappe S,Madhi F,Ulinski T,Mahr A

    更新日期:2018-11-01 00:00:00

  • Physician advice to adolescents about drinking and other health behaviors.

    abstract:BACKGROUND:This report assessed the proportion of US 10th graders (average age, 16) who saw a physician in the past year and were asked and given advice about their drinking. We hypothesized that advice would vary by whether students were asked about drinking and their drinking, bingeing, and drunkenness frequency. ME...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-1496

    authors: Hingson RW,Zha W,Iannotti RJ,Simons-Morton B

    更新日期:2013-02-01 00:00:00

  • Wide variation in reference values for aluminum levels in children.

    abstract:BACKGROUND:Some parents are requesting aluminum testing in their children with developmental issues. Although aluminum can be measured in plasma, serum, or urine, there is scant scientific information about normal ranges. We sought to determine the basis for laboratory reference ranges and whether these ranges are appl...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-3481

    authors: Zeager M,Woolf AD,Goldman RH

    更新日期:2012-01-01 00:00:00

  • Obesity at the onset of diabetes in an ethnically diverse population of children: what does it mean for epidemiologists and clinicians?

    abstract:OBJECTIVE:It is often difficult to determine the pathophysiology of childhood diabetes at onset, particularly in overweight children, because obesity has been associated with both type 1 and type 2 diabetes. We compared children at the diagnosis of diabetes in a multiethnic population-based registry to understand the e...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1448

    authors: Lipton RB,Drum M,Burnet D,Rich B,Cooper A,Baumann E,Hagopian W

    更新日期:2005-05-01 00:00:00

  • Prolonged mechanical ventilation and intracranial hemorrhage: impact on developmental progress through 18 months in infants weighing 1,200 grams or less at birth.

    abstract::In this prospective, longitudinal study, the relative impact of intracranial hemorrhage and prolonged mechanical ventilation on developmental progress during the first 18 months of life of infants weighing 1,200 g or less at birth was examined. A total of 159 surviving infants were divided into two groups: infants wit...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Bozynski ME,Nelson MN,Matalon TA,O'Donnell KJ,Naughton PM,Vasan U,Meier WA,Ploughman L

    更新日期:1987-05-01 00:00:00

  • Cognitive outcomes after neonatal encephalopathy.

    abstract:OBJECTIVES:To describe the spectrum of cognitive outcomes of children with and without cerebral palsy (CP) after neonatal encephalopathy, evaluate the prognostic value of early developmental testing and report on school services and additional therapies. METHODS:The participants of this study are the school-aged survi...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2014-1566

    authors: Pappas A,Shankaran S,McDonald SA,Vohr BR,Hintz SR,Ehrenkranz RA,Tyson JE,Yolton K,Das A,Bara R,Hammond J,Higgins RD,Hypothermia Extended Follow-up Subcommittee of the Eunice Kennedy Shriver NICHD Neonatal Research Network.

    更新日期:2015-03-01 00:00:00

  • Please Test My Child for a Cancer Gene, but Don't Tell Her.

    abstract::A 38-year-old woman is diagnosed with Li-Fraumeni syndrome, an autosomal dominant genetic condition that predisposes to a variety of cancers. The woman has an 11-year-old daughter. The geneticist recommends that the child be tested for the Li-Fraumeni genetic variant. The mother is concerned about the impact of testin...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-2238

    authors: Bester J,Sabatello M,van Karnebeek CDM,Lantos JD

    更新日期:2018-04-01 00:00:00

  • Translating child abuse research into action.

    abstract::The Child Abuse Recognition Experience Study revealed that primary care clinicians did not always follow the legal mandate to report suspected child abuse to child protective services. National child abuse experts representing different disciplines met in a 2-day conference in January 2007 to discuss and develop new s...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-0715c

    authors: Flaherty EG,Sege RD,Hurley TP

    更新日期:2008-09-01 00:00:00

  • Utilization of pediatric hospitals in New York State.

    abstract:BACKGROUND:Little published information is available regarding the proportion of hospitals that offer pediatric services at specified levels, or the actual utilization of such services. OBJECTIVE:To determine if an existing national accreditation process created for educational purposes identifies hospitals with a dis...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.111.5.1068

    authors: Kanter RK,Egan M

    更新日期:2003-05-01 00:00:00

  • Predicting time to hospital discharge for extremely preterm infants.

    abstract:BACKGROUND:As extremely preterm infant mortality rates have decreased, concerns regarding resource use have intensified. Accurate models for predicting time to hospital discharge could aid in resource planning, family counseling, and stimulate quality-improvement initiatives. OBJECTIVES:To develop, validate, and compa...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-0810

    authors: Hintz SR,Bann CM,Ambalavanan N,Cotten CM,Das A,Higgins RD,Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.

    更新日期:2010-01-01 00:00:00

  • Healing of hymenal injuries in prepubertal and adolescent girls: a descriptive study.

    abstract:OBJECTIVE:The objective of this study was to identify the healing process and outcome of hymenal injuries in prepubertal and adolescent girls. METHODS:This multicenter, retrospective project used photographs to document the healing process and outcome of hymenal trauma that was sustained by 239 prepubertal and puberta...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2006-0964

    authors: McCann J,Miyamoto S,Boyle C,Rogers K

    更新日期:2007-05-01 00:00:00

  • Screening and counseling associated with obesity diagnosis in a national survey of ambulatory pediatric visits.

    abstract:OBJECTIVE:To examine clinician-reported diagnosis of obesity and frequency of blood pressure assessment and diet and exercise counseling during ambulatory visits made by children and adolescents. METHODS:The National Ambulatory Medical Care Survey and National Hospital Ambulatory Medical Care Survey 1997 to 2000 were ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1517

    authors: Cook S,Weitzman M,Auinger P,Barlow SE

    更新日期:2005-07-01 00:00:00

  • Hepatitis C Testing Among Perinatally Exposed Infants.

    abstract:BACKGROUND:Hepatitis C virus (HCV) prevalence doubled among pregnant women from 2009 to 2014, reaching 3.4 per 1000 births nationwide. Infants exposed to HCV may acquire HCV by vertical transmission. National guidelines recommend that infants exposed to HCV be tested; however, it is unclear if these recommendations are...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-2482

    authors: Lopata SM,McNeer E,Dudley JA,Wester C,Cooper WO,Carlucci JG,Espinosa CM,Dupont W,Patrick SW

    更新日期:2020-03-01 00:00:00

  • Athletic participation by children and adolescents who have systemic hypertension. American Academy of Pediatrics Committee on Sports Medicine and Fitness.

    abstract::Children and adolescents who have systemic hypertension may be at risk for complications when exercise causes their blood pressures to rise even higher. The purpose of this statement is to make recommendations concerning the athletic participation of individuals with hypertension using the 26th Bethesda Conference on ...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章,实务指引

    doi:10.1542/peds.99.4.637

    authors:

    更新日期:1997-04-01 00:00:00

  • Use of wireless capsule endoscopy in the management of severe Henoch-Schonlein purpura.

    abstract::Henoch-Schonlein purpura is a multisystem vasculitis that primarily affects children. Characteristic symptoms include purpura of the lower extremities and buttocks, abdominal pain, arthralgias, and hematuria. Gastrointestinal bleeding occurs in approximately 50% of children and, although often self-limiting, can be si...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-3111

    authors: Preud'Homme DL,Michail S,Hodges C,Milliken T,Mezoff AG

    更新日期:2006-09-01 00:00:00

  • Psychosocial outcomes of fetal alcohol syndrome in adulthood.

    abstract:BACKGROUND AND OBJECTIVE:Primary disabilities in children prenatally exposed to alcohol have a major impact on their daily life. It is suggested that these issues persist into adulthood, but few studies have addressed the outcome in adults with prenatal exposure, especially those with fetal alcohol syndrome (FAS). The ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2014-1915

    authors: Rangmar J,Hjern A,Vinnerljung B,Strömland K,Aronson M,Fahlke C

    更新日期:2015-01-01 00:00:00

  • Recent trends in waist circumference and waist-height ratio among US children and adolescents.

    abstract:OBJECTIVES:Abdominal obesity may be a better predictor than overall obesity for the risk of cardiovascular disease and type 2 diabetes. Waist circumference and waist-height ratio are 2 simple, yet effective, surrogate measures of abdominal obesity. We sought to examine the recent trends in mean waist circumference and ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-1062

    authors: Li C,Ford ES,Mokdad AH,Cook S

    更新日期:2006-11-01 00:00:00

  • Obesity risk for female victims of childhood sexual abuse: a prospective study.

    abstract:OBJECTIVE:Efforts are under way to articulate environmental, psychosocial, and biological conditions that may predispose the development and maintenance of obesity. There is increasing evidence that adverse childhood experiences such as childhood abuse may be implicated in the development of obesity. Given the dearth o...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-3058

    authors: Noll JG,Zeller MH,Trickett PK,Putnam FW

    更新日期:2007-07-01 00:00:00

  • Insulin receptors in cystic fibrosis: increased receptor number and altered affinity.

    abstract::Patients with cystic fibrosis are known to have pancreatic disorganization with associated pancreatic exocrine insufficiency. Endocrine hormonal secretion is also affected but diminution in insulin secretion is rarely accompanied by overt diabetes. We studied seven patients with cystic fibrosis to determine their carb...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Lippe BM,Kaplan SA,Neufeld ND,Smith A,Scott M

    更新日期:1980-05-01 00:00:00

  • The Maternal Phenylketonuria Project: a summary of progress and challenges for the future.

    abstract::The results of the International Collaborative Study of Maternal phenylketonuria have shown that dietary phenylalanine restriction of women with hyperphenylalaninemia during pregnancy decreases the incidence of mental retardation, microcephaly, congenital heart disease, and intrauterine growth retardation in their off...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Clarke JT

    更新日期:2003-12-01 00:00:00

  • Overweight among low-income preschool children associated with the consumption of sweet drinks: Missouri, 1999-2002.

    abstract:OBJECTIVE:To examine the association between sweet drink consumption and overweight among preschool children. METHODS:A retrospective cohort design was used to examine the association between sweet drink consumption and overweight at follow-up among 10904 children who were aged 2 and 3 years and had height, weight, an...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1148

    authors: Welsh JA,Cogswell ME,Rogers S,Rockett H,Mei Z,Grummer-Strawn LM

    更新日期:2005-02-01 00:00:00

  • Predictability of esophageal injury from signs and symptoms: a study of caustic ingestion in 378 children.

    abstract::The accuracy of signs and symptoms as predictors of the presence and severity of esophageal injury was evaluated in 378 children admitted to three pediatric hospitals between 1970 and 1980. The signs and symptoms analyzed included nausea, vomiting, dysphagia, refusal to drink, abdominal pain, increased salivation, oro...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gaudreault P,Parent M,McGuigan MA,Chicoine L,Lovejoy FH Jr

    更新日期:1983-05-01 00:00:00