Abstract:
:The results of the International Collaborative Study of Maternal phenylketonuria have shown that dietary phenylalanine restriction of women with hyperphenylalaninemia during pregnancy decreases the incidence of mental retardation, microcephaly, congenital heart disease, and intrauterine growth retardation in their offspring. The best results are achieved when treatment is initiated before conception. Psychosocial problems are the most pervasive obstacle to the achievement of optimum dietary treatment. Novel, nondietary approaches to the treatment of maternal phenylketonuria are under development.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Clarke JTsubject
Has Abstractpub_date
2003-12-01 00:00:00pages
1584-7issue
6 Pt 2eissn
0031-4005issn
1098-4275journal_volume
112pub_type
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