Pre-endoscopic medication. A randomized double-blind trial of atropine and meperidine as a supplement to diazepam.

Abstract:

:The effects of an intramuscular injection of atropine (0.6 mg) and meperidine (1 mg/kg body weight) 30 min before topical benzocaine and intravenous diazepam administration were compared with those of a control group that received only benzocaine and intravenous diazepam in a randomized double-blind controlled trial of premedication for upper gastrointestinal endoscopy in 100 consecutive patients. Atropine and meperidine decreased the amount of salivation and gastric secretion (p less than 0.001 and p less than 0.001, respectively) and increased the period of sedation (p less than 0.001). The patients' and examiners' evaluation of the procedure was the same with either premedication regimen. Neither regimen affected the success rate of the endoscopy. Regardless of the regimen used, every patient who underwent endoscopy stated that they would consent to another examination, if necessary. Patients judged before endoscopy to be most apprehensive tolerated the procedure least, and those judged to be least apprehensive tolerated the procedure best, irrespective of premedication. The addition of meperidine and atropine to a premedication regimen of diazepam and topical benzocaine does not appear to be beneficial.

journal_name

Scand J Gastroenterol

authors

Schwartz SE,Fazio TL

doi

10.3109/00365527909181948

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

747-51

issue

6

eissn

0036-5521

issn

1502-7708

journal_volume

14

pub_type

临床试验,杂志文章,随机对照试验
  • A systematic approach to the preparation of 125I-labeled gastrointestinal regulatory peptides with high specific radioactivities.

    abstract::A systematic approach is outlined for the preparation of a whole series of immunoreactive 125I-labeled gastrointestinal regulatory peptides with high specific radioactivities. In our hands, the theoretically superior Iodo-gen method has no more to offer than the harsher chloramine-T method in the iodination of secreti...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528509089682

    authors: Burhol PG,Jorde R,Florholmen J,Jenssen TG,Vonen B

    更新日期:1985-05-01 00:00:00

  • Adhesion of bacteria to the human small-intestinal mucosa. A scanning electron microscopic study.

    abstract::During the period 1 January 1980 to 30 June 1986, a total of 543 small-intestinal biopsy specimens from adults with gastrointestinal symptoms were available for routine analysis with correlated scanning electron microscopy and light microscopy. Adhesion of microorganisms was found in 77 biopsy specimens. Microorganism...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528909089229

    authors: Hörstedt P,Danielsson A,Nyhlin H,Stenling R,Suhr O

    更新日期:1989-09-01 00:00:00

  • Colonic epithelial cell expression of ICAM-1 relates to loss of surface continuity: a comparative study of inflammatory bowel disease and colonic neoplasms.

    abstract:OBJECTIVE:Intercellular adhesion molecule-1 (ICAM-1) is important in ulcerative colitis (UC) by mediating the arrest and further migration of neutrophils. In vitro studies have shown that colonocytes from chronically inflamed colon and cultured colon cancer cells are capable of expressing ICAM-1. The aim of this study ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520510024241

    authors: Vainer B,Horn T,Nielsen OH

    更新日期:2006-03-01 00:00:00

  • Faecal calprotectin shedding after short-term treatment with non-steroidal anti-inflammatory drugs.

    abstract:BACKGROUND:Increased faecal calprotectin shedding indicates gastrointestinal mucosal inflammation. METHODS:We studied the effect of short-term treatment with non-steroidal anti-inflammatory drugs (NSAIDs) on faecal calprotectin shedding in two randomized crossover studies, with treatment regimens of indomethacin or na...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365529609006407

    authors: Meling TR,Aabakken L,Røseth A,Osnes M

    更新日期:1996-04-01 00:00:00

  • Role of aging in the expression of Helicobacter pylori gastritis in the antrum, corpus, and cardia.

    abstract:BACKGROUND:Earlier studies identified a pylorocardial expansion of chronic gastritis. We investigated the age-dependent changes in grading and topography of Helicobacter pylori gastritis. METHODS:Antral, corpus, and cardial biopsy specimens from 216 H. pylori-positive patients with no peptic ulcer disease (PUD), malig...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365529950172989

    authors: Hackelsberger A,Günther T,Schultze V,Peitz U,Malfertheiner P

    更新日期:1999-02-01 00:00:00

  • Role of anti-parietal cell antibody in Helicobacter pylori-associated atrophic gastritis: evaluation in a country of high prevalence of atrophic gastritis.

    abstract:BACKGROUND:Helicobacter pylori plays an important part in the progression of atrophic gastritis; however, markers for predicting the progression of atrophic gastritis remain unidentified. We investigated the relation between the degree of atrophic gastritis and the amount of anti-parietal cell antibodies (APCAs) presen...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655202317284183

    authors: Ito M,Haruma K,Kaya S,Kamada T,Kim S,Sasaki A,Sumii M,Tanaka S,Yoshihara M,Chayama K

    更新日期:2002-03-01 00:00:00

  • Extracellular vesicle-associated soluble CD163 and CD206 in patients with acute and chronic inflammatory liver disease.

    abstract::Background: Extracellular vesicles (EVs) are implicated in intercellular communication in liver diseases. An EV-associated fraction of the macrophage biomarker soluble CD163, denoted EV-CD163, was recently identified. EV-CD163 may be released during later phases of the inflammatory response as opposed to the acute she...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2020.1759140

    authors: Nielsen MC,Andersen MN,Grønbæk H,Damgaard Sandahl T,Møller HJ

    更新日期:2020-05-01 00:00:00

  • Genetic risk factors for serious infections in inflammatory bowel diseases.

    abstract:INTRODUCTION:Immunosuppression, the cornerstone of management of Crohn's disease (CD) and ulcerative colitis (UC) (inflammatory bowel diseases; IBD) is associated with an increased risk of serious infections that is inadequately predicted by clinical risk factors. The role of genetics in determining susceptibility to i...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1286381

    authors: Sasidharan S,Yajnik V,Khalili H,Garber J,Xavier R,Ananthakrishnan AN

    更新日期:2017-05-01 00:00:00

  • Changes in inflammatory bowel disease subtype during follow-up and over time in 44,302 patients.

    abstract:AIM:To investigate inflammatory bowel disease (IBD) register-based subtype classifications over a patient's disease course and over time. METHODS:We examined International Classification of Diseases coding in patients with ≥2 IBD diagnostic listings in the National Patient Register 2002-2014 (n = 44,302). RESULTS:18%...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1564361

    authors: Everhov ÅH,Sachs MC,Malmborg P,Nordenvall C,Myrelid P,Khalili H,Elmberg M,Ekbom A,Askling J,Jakobsson G,Halfvarson J,Ludvigsson JF,Olén O

    更新日期:2019-01-01 00:00:00

  • Cephalic phase of pancreatic-polypeptide secretion studied by sham feeding in man.

    abstract::The effect of sham feeding on pancreatic-polypeptide (PP) secretion was studied in 26 duodenal ulcer (DU) patients and in 8 healthy subjects. Modified sham feeding (MSF) by the 'chew and spit' technique induced a rapid increase in plasma concentrations of PP both in DU patients, 56 (2-138) pmol/l, and in the healthy s...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365527909179889

    authors: Schwartz TW,Stenquist B,Olbe L

    更新日期:1979-01-01 00:00:00

  • Effect of AndoSan™ on expression of adhesion molecules and production of reactive oxygen species in human monocytes and granulocytes in vivo.

    abstract:BACKGROUND:Oral intake (60 ml daily) over 12 days in eight healthy volunteers of an immunostimulatory extract based on the medicinal mushroom Agaricus blazei Murill (AbM (AndoSan™)), reduced the monocyte and granulocyte release of mainly proinflammatory cytokines in vivo, suggesting an anti-inflammatory effect. In this...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2012.660544

    authors: Johnson E,Førland DT,Hetland G,Sætre L,Olstad OK,Lyberg T

    更新日期:2012-09-01 00:00:00

  • Urinary prostaglandins and renal function in chronic liver diseases.

    abstract::Changes in urinary PGE2 and PGF2 alpha excretion in chronic liver diseases were observed in relation to renal hemodynamics and sodium balance. After equilibration on a 110-170-meq sodium diet, daily urine collections were analyzed for PGE2 and PGF2 alpha by a new extraction and radioimmunoassay method. PGE2 was signif...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528609034626

    authors: Uemura M,Tsujii T,Fukui H,Kita K,Takaya A,Tsukamoto N,Nakayama M,Matsumoto M,Tamura M

    更新日期:1986-01-01 00:00:00

  • Mortality associated with gastroesophageal reflux disease and its non-malignant complications: a systematic review.

    abstract:OBJECTIVE:The mortality associated with malignant complications of gastroesophageal reflux disease (GERD) is well recognized. The aim of this systematic review was to assess the less well-examined mortality associated with GERD and its non-malignant complications, including esophageal erosions, ulcers, bleeding, perfor...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1080/00365520701785475

    authors: Becher A,El-Serag HB

    更新日期:2008-01-01 00:00:00

  • Pancreatic duct changes are not associated with early signs of chronic pancreatitis at magnetic resonance imaging (MRI) in patients with primary sclerosing cholangitis.

    abstract:OBJECTIVE:The association between chronic pancreatitis (CP) and primary sclerosing cholangitis (PSC) has been reported previously. The aims of the present study were to evaluate the presence of early pancreatic abnormalities and duct changes, using MRCP/MRI in PSC and to evaluate possible risk factors for these changes...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521003793741

    authors: Said K,Albiin N,Lindberg B,Brismar TB,Karrar A,Permert J,Bergquist A

    更新日期:2010-08-01 00:00:00

  • Evaluation of the marker technique for measurement of exocrine pancreatic secretion rate.

    abstract::A secretin-cholecystokinin test was performed in 103 patients, representing both normal and reduced exocrine pancreatic function. The duodenum was intubated with a triple-lumen tube. The gastric and duodenal contents were aspirated separately and sampled in 10-min periods. An inert, water-soluble marker (58Co-vitamin ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3109/00365528509089691

    authors: Rune SJ,Worning H

    更新日期:1985-05-01 00:00:00

  • Association of beta-defensin 1 single nucleotide polymorphisms with Crohn's disease.

    abstract:OBJECTIVE:It has been suggested that deficient defensin expression is associated with the chronic inflammation of Crohn's disease. The regional localization of Crohn's disease, ileal or colonic disease can be linked to different defensin profiles. As constitutive beta-defensin 1 has a colonic expression, we considered ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520701682615

    authors: Kocsis AK,Lakatos PL,Somogyvári F,Fuszek P,Papp J,Fischer S,Szamosi T,Lakatos L,Kovacs A,Hofner P,Mándi Y

    更新日期:2008-03-01 00:00:00

  • Metronidazole in Crohn's disease. A double blind cross-over clinical trial.

    abstract::Twenty-two patients with active Crohn's disease treated with salazosulfapyridin or prednisone, were in addition given metronidazole 1.000 mg daily or placebo for two months each in a double-blind cross-over study. No statistically significant effect was observed on the overall clinical condition in the 20 patients who...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365527809179816

    authors: Blichfeldt P,Blomhoff JP,Myhre E,Gjone E

    更新日期:1978-01-01 00:00:00

  • Outpatient management of acute uncomplicated diverticulitis results in health-care cost savings.

    abstract:PURPOSE:Outpatient management without antibiotics has been shown to be safe for selected patients diagnosed with acute uncomplicated diverticulitis (AUD). The aim of this study was to evaluate the impact on admissions, complication rates and health-care costs of the policy of outpatient treatment without using antibiot...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1448887

    authors: Isacson D,Andreasson K,Nikberg M,Smedh K,Chabok A

    更新日期:2018-04-01 00:00:00

  • Gastric IgA in cystic fibrosis in relation to the migrating motor complex.

    abstract:BACKGROUND:Gastrointestinal symptoms in cystic fibrosis are frequent, but little is known about the underlying pathophysiology. Mucosal secretion of IgA is important for the immunologic function in the human gastrointestinal tract but has not been studied in cystic fibrosis. The aim of this study was to quantify the re...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655201750313379

    authors: Hallberg K,Mattsson-Rydberg A,Fändriks L,Strandvik B

    更新日期:2001-08-01 00:00:00

  • Short stricture of the rectum regressing on discontinuation of hormone replacement therapy: endoscopic appearance, multiple biopsies and clinical improvement insufficient for diagnosis.

    abstract::A short, benign-looking stricture of the rectum presented itself clinically as subileus in a middle-aged woman after 5 years on hormone replacement therapy (HRT) and 8 years after curative surgery for cancer of the ovaries. Radiological work-up and multiple, repeated biopsies supported the endoscopically appearing ben...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520510011614

    authors: Hoff G,Wiig J,Reed W,Hole KH,Scheistrøen M,Henriksen H

    更新日期:2005-03-01 00:00:00

  • The storage time of monoiodinated gastrin affects the biological activity and binding to rat fundic plasma membranes similarly, whereas the immunoreactivity is less affected.

    abstract::Monoiodinated gastrin was produced by a gentle Iodo-gen method, followed by gel and ion-exchange chromatography. During storage this tracer has previously been found to retain its immunological activity, whereas its specific binding to rat gastric fundic plasma membranes decreased rapidly. To examine whether the loss ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528708991480

    authors: Kleveland PM,Waldum HL

    更新日期:1987-05-01 00:00:00

  • The effect of cisapride and ranitidine as monotherapies and in combination in the treatment of uncomplicated gastric ulceration.

    abstract:BACKGROUND:Stimulation of gastric motility has been supposed to accelerate the healing of gastric ulcer. The combination of the prokinetic drug cisapride and the H2 blocker ranitidine was tested in the treatment of uncomplicated gastric ulcer. METHODS:Cisapride, 20 mg twice daily (Cis), and ranitidine, 150 mg twice da...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.3109/00365529509093246

    authors: Stubberöd A,Glise H,Hallerbäck B,Solhaug JH

    更新日期:1995-02-01 00:00:00

  • Depletion of enteric gonadotropin-releasing hormone is found in a few patients suffering from severe gastrointestinal dysmotility.

    abstract:OBJECTIVE:Many patients, especially women, suffer from severe gastrointestinal pain and dysmotility for several years without being diagnosed. Depletion of gonadotropin-releasing hormone (GnRH) in the enteric nervous system (ENS) has been described in some patients. The aim of this study was to examine the expression o...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2012.706826

    authors: Hammar O,Ohlsson B,Veress B,Alm R,Fredrikson GN,Montgomery A

    更新日期:2012-10-01 00:00:00

  • The effects of intravenous urea infusions on portal and arterial plasma ammonia and urea enrichment of jejunal and colonic infusions. Acute experiments with growing pigs.

    abstract::Six pigs (49-69 kg) were anaesthetized and fitted with cannulas in the brachiocephalic artery and portal and jugular veins. In addition, inlet-outlet perfusion cannulas were placed in segments of the small and large intestine. Intravenous infusion of urea for 2 h increased arterial plasma urea from a base-line level o...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529209000129

    authors: Malmlöf K,Simoes Nunes C

    更新日期:1992-07-01 00:00:00

  • Endogenous activation of prostaglandin synthesis in rabbit colonic explants cultured in vitro.

    abstract::Rabbit colonic biopsy specimens cultured in vitro showed an optimal release of prostaglandin E2 (PGE2) after 6-7 h of incubation. The amplitude but not the PGE2 production profile was dependent on stimuli applied--that is, A23187 greater than phorbol 12-myristate 13-acetate greater than control. This study was underta...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529109025029

    authors: Nygård G,Berglindh T

    更新日期:1991-02-01 00:00:00

  • Can famotidine and omeprazole be combined on a once-daily basis?

    abstract:OBJECTIVE:Prompt and long-standing acid control following once-daily administration of antisecretory drugs is desirable. The objective of this study was to determine whether co-administration of a well-characterized H2-receptor antagonist, famotidine, can be combined with the proton-pump inhibitor omeprazole. MATERIAL...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/00365520601026665

    authors: Fändriks L,Lönroth H,Pettersson A,Vakil N

    更新日期:2007-06-01 00:00:00

  • Mortality in high-risk patients with bleeding Mallory-Weiss syndrome is similar to that of peptic ulcer bleeding. Results of a prospective database study.

    abstract:OBJECTIVE:The aim of this study was to identify the predictive factors influencing mortality in patients with bleeding Mallory-Weiss syndrome in comparison with peptic ulcer bleeding. MATERIAL AND METHODS:Between January 2005 and December 2009, 281 patients with endoscopically confirmed Mallory-Weiss syndrome and 1530...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3109/00365521.2013.846404

    authors: Ljubičić N,Budimir I,Pavić T,Bišćanin A,Puljiz Z,Bratanić A,Troskot B,Zekanović D

    更新日期:2014-04-01 00:00:00

  • The impact of atopic disease on the risk of post-infectious fatigue and irritable bowel syndrome 3 years after Giardia infection. A historic cohort study.

    abstract:OBJECTIVE:To investigate whether atopic disease influences the prevalence of irritable bowel syndrome (IBS) and chronic fatigue (CF) after giardiasis. METHODS:A questionnaire was sent to all confirmed cases of giardiasis after a Norwegian outbreak, with response rate of 65.3% (817/1252). Controls were randomly selecte...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2012.696681

    authors: Hunskar GS,Langeland N,Wensaas KA,Hanevik K,Eide GE,Mørch K,Rortveit G

    更新日期:2012-09-01 00:00:00

  • Colorectal endoscopic submucosal dissection (ESD) in the West - when can satisfactory results be obtained? A single-operator learning curve analysis.

    abstract:OBJECTIVES:Up to date we lack a detailed description of the colorectal endoscopic submucosal dissection (ESD) learning curve, that would represent the experience of the Western center. The aim of this study was to define the critical points of the learning curve and to draw up lesions qualification guidelines tailored ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.1080/00365521.2017.1379557

    authors: Spychalski M,Skulimowski A,Dziki A,Saito Y

    更新日期:2017-12-01 00:00:00

  • The effect of proteolytic enzymes on the vitamin B12-binding proteins of human gastric juice and saliva.

    abstract::Pepsin had no effect on the vitamin B12 binder in human saliva (R-binder), while trypsin was found to reduce the apparent molecular weight of the R-binder and to release vitamin B12 from the R-B12complex of human saliva and human gastric juice (HGJ). Trypsin had no effect on the molecular weight and biological activit...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365527909181412

    authors: Andersen KJ,von der Lippe G

    更新日期:1979-01-01 00:00:00