Albuterol protects against exercise-induced asthma longer than metaproterenol sulfate.

Abstract:

:Both metaproterenol sulfate and albuterol are inhaled medications commonly used to prevent exercise-induced bronchospasm. Their efficacy and duration of action in controlling exercise-induced bronchospasm were compared with placebo in 18 asthmatic children (age range: 12 to 17 years) in a single-blind randomized crossover study. Standardized treadmill exercise challenges were repeated every two hours for up to six hours following the initial exercise test. With the initial exercise challenge, both active medications blocked exercise-induced bronchospasm with equal efficacy. On the other hand, when the duration of action of the medications was compared: albuterol blocked exercise-induced bronchospasm longer than metaproterenol sulfate in eight subjects, the reverse was true in only one patient, and the medications blocked for equal duration in nine subjects. Thus, although both active agents were equally efficacious in blocking exercise-induced bronchospasm initially, the duration of action of albuterol was significantly (P less than .05) longer on serial testing than that of metaproterenol sulfate. Both medications were significantly better than placebo in efficacy and duration of action.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Berkowitz R,Schwartz E,Bukstein D,Grunstein M,Chai H

subject

Has Abstract

pub_date

1986-02-01 00:00:00

pages

173-8

issue

2

eissn

0031-4005

issn

1098-4275

journal_volume

77

pub_type

临床试验,杂志文章,随机对照试验
  • Physician Communication Training and Parental Vaccine Hesitancy: A Randomized Trial.

    abstract:BACKGROUND AND OBJECTIVES:Physicians have a major influence on parental vaccine decisions. We tested a physician-targeted communication intervention designed to (1) reduce vaccine hesitancy in mothers of infants seen by trained physicians and (2) increase physician confidence in communicating about vaccines. METHODS:W...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2014-3199

    authors: Henrikson NB,Opel DJ,Grothaus L,Nelson J,Scrol A,Dunn J,Faubion T,Roberts M,Marcuse EK,Grossman DC

    更新日期:2015-07-01 00:00:00

  • Coarctation of the abdominal aorta and renal artery stenosis related to an umbilical artery catheter placement in a neonate.

    abstract::Umbilical artery catheters have been associated with thrombotic complications, such as partial or complete occlusion in the aorta, the renal arteries, and other blood vessels. There have been few reports of the long-term consequences of either symptomatic or asymptomatic thrombi. We report a patient, now 22 years of a...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.106.3.e36

    authors: Adelman RD,Morrell RE

    更新日期:2000-09-01 00:00:00

  • Translating child abuse research into action.

    abstract::The Child Abuse Recognition Experience Study revealed that primary care clinicians did not always follow the legal mandate to report suspected child abuse to child protective services. National child abuse experts representing different disciplines met in a 2-day conference in January 2007 to discuss and develop new s...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-0715c

    authors: Flaherty EG,Sege RD,Hurley TP

    更新日期:2008-09-01 00:00:00

  • Blueprint for Action: Visioning Summit on the Future of the Workforce in Pediatrics.

    abstract::The Federation of Pediatric Organizations engaged members of the pediatric community in an 18-month process to envision the future of the workforce in pediatrics, culminating in a Visioning Summit on the Future of the Workforce in Pediatrics. This article documents the planning process and methods used. Four working g...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2014-3493

    authors: Sectish TC,Hay WW Jr,Mahan JD,Mendoza FS,Spector ND,Stanton B,Szilagyi PG,Turner TL,Walker LR,Slaw K,members of the Federation of Pediatric Organizations' Visioning Summit Working Groups and Planning Committee.

    更新日期:2015-07-01 00:00:00

  • Fibromyalgia syndrome in children and adolescents: clinical features at presentation and status at follow-up.

    abstract:OBJECTIVES:To 1) describe the characteristic features of fibromyalgia syndrome (FS) in a pediatric population, 2) note similarities and differences with FS in adults, and 3) determine outcome after treatment. SETTING AND DESIGN:The Pediatric Rheumatology Clinic at the University of Rochester Medical Center is staffed ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.101.3.377

    authors: Siegel DM,Janeway D,Baum J

    更新日期:1998-03-01 00:00:00

  • A systematic review of vocational interventions for young adults with autism spectrum disorders.

    abstract:BACKGROUND AND OBJECTIVE:Many individuals with autism spectrum disorders (ASDs) are approaching adolescence and young adulthood; interventions to assist these individuals with vocational skills are not well understood. This study systematically reviewed evidence regarding vocational interventions for individuals with A...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2012-0682

    authors: Taylor JL,McPheeters ML,Sathe NA,Dove D,Veenstra-Vanderweele J,Warren Z

    更新日期:2012-09-01 00:00:00

  • Simulation in Pediatric Emergency Medicine Fellowships.

    abstract:BACKGROUND AND OBJECTIVES:Graduate medical education faces challenges as programs transition to the next accreditation system. Evidence supports the effectiveness of simulation for training and assessment. This study aims to describe the current use of simulation and barriers to its implementation in pediatric emergenc...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2014-4158

    authors: Doughty CB,Kessler DO,Zuckerbraun NS,Stone KP,Reid JR,Kennedy CS,Nypaver MM,Auerbach MA

    更新日期:2015-07-01 00:00:00

  • Practice parameter: long-term treatment of the child with simple febrile seizures. American Academy of Pediatrics. Committee on Quality Improvement, Subcommittee on Febrile Seizures.

    abstract::The Committee on Quality Improvement, Subcommittee on Febrile Seizures, of the American Academy of Pediatrics, in collaboration with experts from the Section on Neurology, general pediatricians, consultants in the fields of child neurology and epilepsy, and research methodologists, developed this practice parameter. T...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章,实务指引

    doi:10.1542/peds.103.6.1307

    authors:

    更新日期:1999-06-01 00:00:00

  • Defining successful performance among pediatric residents.

    abstract::The pediatric literature has documented a growing attention to defining the nature and quality of residency training. The critical incident technique, a method widely accepted in industrial settings, was used in this study to determine attitudes and behaviors deemed critical for successful performance of residents in ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Altmaier EM,McGuinness G,Wood P,Ross RR,Bartley J,Smith W

    更新日期:1990-02-01 00:00:00

  • Deep venous thrombosis complicating myelomeningocele: report of three cases.

    abstract::Deep venous thrombosis is a frequent, well-recognized complication of spinal cord injury. Patients with myelomeningocele often have similar weakness of the lower extremities. Following orthopedic surgery, they may also be immobilized at a time when they are hypercoagulable. In addition, as with patients with spinal co...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Bernstein ML,Esseltine D,Azouz EM,Forbes P

    更新日期:1989-11-01 00:00:00

  • Wide variation in reference values for aluminum levels in children.

    abstract:BACKGROUND:Some parents are requesting aluminum testing in their children with developmental issues. Although aluminum can be measured in plasma, serum, or urine, there is scant scientific information about normal ranges. We sought to determine the basis for laboratory reference ranges and whether these ranges are appl...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-3481

    authors: Zeager M,Woolf AD,Goldman RH

    更新日期:2012-01-01 00:00:00

  • Family history predicts stress fracture in active female adolescents.

    abstract:OBJECTIVE:Increased physical activity and menstrual irregularity have been associated with increased risk for stress fracture among adult women active in athletics. The purposes of this study were to determine whether menstrual irregularity is also a risk factor for stress fracture in active female adolescents and to e...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-2145

    authors: Loud KJ,Micheli LJ,Bristol S,Austin SB,Gordon CM

    更新日期:2007-08-01 00:00:00

  • Hypoxic arousal responses in infants with bronchopulmonary dysplasia.

    abstract::Infants with bronchopulmonary dysplasia have a high incidence of sudden, unexplained death in the postneonatal period, yet the cause of these deaths is unknown. Frequent episodes of clinically unsuspected arterial oxygen desaturation have recently been described in infants with bronchopulmonary dysplasia. We hypothesi...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Garg M,Kurzner SI,Bautista D,Keens TG

    更新日期:1988-07-01 00:00:00

  • Applicability of the Denver Prescreening Developmental Questionnaire in a low-income population.

    abstract::A prospective study was conducted to assess the applicability of the Denver Prescreening Developmental Questionnaire (DPDQ) in a predominantly black, low-income population in Mobile, Alabama. The effect of an educational intervention designed to increase the accuracy of parental responses to the DPDQ was also assessed...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Rosenbaum MS,Chua-Lim C,Wilhite J,Mankad VN

    更新日期:1983-03-01 00:00:00

  • Missed opportunities for childhood vaccinations in office practices and the effect on vaccination status.

    abstract::To determine the rate of childhood under-vaccination, rate and types of missed opportunities (MOs) for vaccinations, and the contribution of MOs to the undervaccination of preschool-age children, the authors conducted a retrospective medical chart review in seven primary care settings in the Rochester, NY, area: a hos...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Szilagyi PG,Rodewald LE,Humiston SG,Raubertas RF,Cove LA,Doane CB,Lind PH,Tobin MS,Roghmann KJ,Hall CB

    更新日期:1993-01-01 00:00:00

  • Clinical profile of 30 infants with acute pulmonary hemorrhage in Cleveland.

    abstract::Between 1993 and 2000, 30 infants were hospitalized with acute pulmonary hemorrhage at Rainbow Babies and Children's Hospital in Cleveland. Most infants presented with severe pulmonary symptoms requiring intensive support, but a few infants had less severe hemorrhage. Three quarters of the patients required ventilator...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.110.3.627

    authors: Dearborn DG,Smith PG,Dahms BB,Allan TM,Sorenson WG,Montana E,Etzel RA

    更新日期:2002-09-01 00:00:00

  • Hypocalcemic coma following two pediatric phosphate enemas.

    abstract::Coma, tetany, dehydration, hypotension, tachycardia, and hyperpyrexia developed in a 2 1/2-year-old girl following two hypertonic phosphate pediatric enemas. She had marked hyperphosphatemia, hypocalcemia, hypernatremia, and acidosis. Hypocalcemia due to hyperphosphatemia can explain all of these findings. Calculation...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Sotos JF,Cutler EA,Finkel MA,Doody D

    更新日期:1977-09-01 00:00:00

  • When is lack of supervision neglect?

    abstract::Occasionally, pediatricians become aware of children who are inadequately supervised. More frequently, pediatricians treat children for traumatic injuries or ingestions that they suspect could have been prevented with better supervision. This clinical report contains guidance for pediatricians considering a referral t...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章

    doi:10.1542/peds.2006-1780

    authors: Hymel KP,Committee on Child Abuse and Neglect.

    更新日期:2006-09-01 00:00:00

  • Effect of iron therapy on behavior performance in nonanemic, iron-deficient infants.

    abstract::In an effort to determine whether iron deficiency, in the absence of anemia (hemoglobin greater than 11.0 g/dL), might produce alterations in behavioral development, four groups of nonanemic infants, 9 to 12 months of age, with varying degrees of iron deficiency were studied. Infants were classified as iron sufficient...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Oski FA,Honig AS,Helu B,Howanitz P

    更新日期:1983-06-01 00:00:00

  • Clinical value of immunoglobulin A antitransglutaminase assay in the diagnosis of celiac disease.

    abstract:OBJECTIVES:Our goal was to evaluate the possible correspondence between antitissue transglutaminase of immunoglobulin A class levels and stage of mucosal damage in patients affected by celiac disease. In addition, we assessed clinical use of antitissue transglutaminase values to predict biopsy results. METHODS:One tho...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-0604

    authors: Diamanti A,Colistro F,Calce A,Devito R,Ferretti F,Minozzi A,Santoni A,Castro M

    更新日期:2006-12-01 00:00:00

  • Addressing parental smoking in pediatrics and family practice: a national survey of parents.

    abstract:BACKGROUND:Parental smoking has been associated with increased rates of sudden infant death syndrome, low birth weight, otitis media, asthma, and decreased lung growth. No prior parent surveys have assessed national rates of screening and counseling for parental tobacco use in the context of their child's visit to prim...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.112.5.1146

    authors: Winickoff JP,McMillen RC,Carroll BC,Klein JD,Rigotti NA,Tanski SE,Weitzman M

    更新日期:2003-11-01 00:00:00

  • The changing role and responsibilities of chairmen in clinical academic departments: the transition from autocracy.

    abstract::There is considerable literature dealing with the responsibilities of clinical department chairmen, which primarily emphasizes the importance of developing a sound and facilitating administration. This is dependent on the hiring of appropriate support personnel, developing a representative committee structure, being a...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Brent RL

    更新日期:1992-07-01 00:00:00

  • Ifosfamide-induced nephrotoxicity in children: critical review of predictive risk factors.

    abstract::Ifosfamide is widely used in the treatment of pediatric solid tumors. Its main adverse effects are various forms of renal tubular and glomerular damage. Many risk factors have been proposed to play a role in the development and severity of nephrotoxicity in children receiving ifosfamide, among which are 1) patient's a...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.101.6.e8

    authors: Loebstein R,Koren G

    更新日期:1998-06-01 00:00:00

  • Clinical and virologic features of hepatitis C virus infection associated with intravenous immunoglobulin.

    abstract:OBJECTIVE:To characterize the clinical features of hepatitis C virus (HCV) infection associated with the administration of intravenous immunoglobulin (IVIG) in patients with varied immunodeficiencies. DESIGN:Prospective collection of clinical and virologic data in patients determined to have HCV exposure associated wi...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Jonas MM,Baron MJ,Bresee JS,Schneider LC

    更新日期:1996-08-01 00:00:00

  • Mortality and morbidity of 500- to 1,499-gram birth weight infants live-born to residents of a defined geographic region before and after neonatal intensive care.

    abstract::All very low-birth-weight infants live-born to residents of an urban southern Ontario county were studied before (1964 to 1969) and after (1973 to 1977) the introduction of neonatal intensive care. Mortality at hospital discharge decreased from 89.4% to 77.6% among infants whose birth weights were 500 to 999 gm and fr...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Horwood SP,Boyle MH,Torrance GW,Sinclair JC

    更新日期:1982-05-01 00:00:00

  • Comparison of perinatal outcomes among TennCare managed care organizations.

    abstract:OBJECTIVE:To compare perinatal outcomes among the managed care organizations (MCOs) providing care to beneficiaries enrolled in TennCare, Tennessee's capitated Medicaid managed care program. DESIGN:Retrospective cohort analysis. SUBJECTS:Infants born in Tennessee during 1995 to women enrolled in TennCare. PRIMARY OU...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.104.3.525

    authors: Cooper WO,Hickson GB,Mitchel EF Jr,Ray WA

    更新日期:1999-09-01 00:00:00

  • Policy statement--Expert witness participation in civil and criminal proceedings.

    abstract::The interests of the public and both the medical and legal professions are best served when scientifically sound and unbiased expert witness testimony is readily available in civil and criminal proceedings. As members of the medical community, patient advocates, and private citizens, pediatricians have ethical and pro...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-1132

    authors: Committee on Medical Liability and Risk Management.

    更新日期:2009-07-01 00:00:00

  • Mechanical vibration in neonatal transport.

    abstract::Mechanical vibration encountered in land transports was assessed objectively through measurement of vertical acceleration experienced by neonates in transit. Vibration was most predominant in the hazardous low frequency range of 3 to 18 Hz. The peak acceleration amplitudes (intermittent thrusts) ranged from 5 to 13 m/...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Shenai JP,Johnson GE,Varney RV

    更新日期:1981-07-01 00:00:00

  • Screening for congenital adrenal hyperplasia: the Delfia Screening Test overestimates serum 17-hydroxyprogesterone in preterm infants.

    abstract:OBJECTIVE:To compare 17-hydroxyprogesterone (17-OHP) levels measured by quantitative serum radioimmunoassay (RIA), including an extraction step, and by screening fluoroimmunoassay (FIA) on blood spots in preterm infants. METHODS:Subjects were 39 healthy infants born at less than 31 weeks' gestational age. Each infant ...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:

    authors: al Saedi S,Dean H,Dent W,Stockl E,Cronin C

    更新日期:1996-01-01 00:00:00

  • Assessment of stress in mothers of children with severe breath-holding spells.

    abstract:BACKGROUND:Severe breath-holding spells (BHS) in children consist of a stereotypical sequence of provocation to cry, noiseless expiration, color change, and loss of consciousness. Parenting a child who exhibits BHS is likely more stressful than parenting a healthy child, owing to this additional medical concern. It is ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.106.1.1

    authors: Mattie-Luksic M,Javornisky G,DiMario FJ

    更新日期:2000-07-01 00:00:00