Human milk-derived growth factor prevents duodenal ulcer formation.

abstract：:Uteroplacental insufficiency increases the risk of perinatal and long-term neurologic morbidity by depriving the fetus of oxidative substrate and causing intrauterine growth retardation. Skeletal muscle and liver from growth retarded fetal and juvenile rats respond to this deprivation by altering mitochondrial gene ex...

journal_title：Pediatric research

authors： Lane RH,Tsirka AE,Gruetzmacher EM

更新日期：2000-06-01 00:00:00

abstract：:To determine the pathophysiologic significance of pertussis toxin (PT) on the human beta-adrenergic system, beta-adrenoceptor (beta-R)-density and cyclic AMP response of peripheral mononuclear blood cells (MN leukocytes) were studied in children during the paroxysmal stage of natural pertussis infection, after vaccina...

journal_title：Pediatric research

authors： Griese M,Sideropoulou O,Reinhardt D

更新日期：1989-02-01 00:00:00

abstract：:Epidermal growth factor (EGF) and transforming growth factor-alpha (TGF-alpha) are mitogenic to the intestinal epithelium. To further clarify their role in the developing human fetal gut, their expression was studied in fetuses at 15 to 20 wk of gestation. TGF-alpha mRNA was present throughout the gastrointestinal tra...

journal_title：Pediatric research

authors： Miettinen PJ

更新日期：1993-05-01 00:00:00

abstract：:We measured the changes in tidal volume, duration of the various phases of the respiratory cycle, and peak nasal pressure during elastic and resistive loading in preterm infants. Values were calculated during the first loaded breath, when chemical drive was unchanged. Tidal volume decreased by equivalent percentages w...

journal_title：Pediatric research

authors： Boychuk RB,Seshia MM,Rigatto H

更新日期：1977-04-01 00:00:00

abstract：:The worldwide burden of disease due to Epstein-Barr virus (EBV) infection is enormous. Diseases include endemic Burkitt lymphoma, infectious mononucleosis, cancers after transplantation, Hodgkin lymphoma, and nasopharyngeal carcinoma. A prophylactic EBV vaccine has the potential to significantly reduce the incidence a...

journal_title：Pediatric research

authors： Balfour HH Jr,Schmeling DO,Grimm-Geris JM

更新日期：2020-01-01 00:00:00

abstract：:Preterm infants are more prone to bone mineral deficiency the lower their birth weight. To achieve the intrauterine bone mineral accretion rate postnatally, 74 low-birth-weight infants (median birth weight, 980 g; range 430-1.580 g) were each supplemented enterally and/or parenterally with calcium and/or phosphorus in...

journal_title：Pediatric research

authors： Pohlandt F

更新日期：1994-01-01 00:00:00

abstract：:Shigellosis in children can cause growth retardation, worsening of malnutrition, and hypoproteinemia. To assess the effects of ingestion of a protein-rich diet during convalescence, 22 children aged 2 to 4 y with culture-proven shigellosis were randomly assigned after 5 d of antibiotic treatment to 21-d feeding regime...

journal_title：Pediatric research

authors： Kabir I,Butler T,Underwood LE,Rahman MM

更新日期：1992-12-01 00:00:00

abstract：:In eight newborn lambs, the adaption of blood to acidosis was studied by sequential measurements of P50 in vitro (pH 7.4; 37 degrees C) and P50 in vivo (animal's pH and temperature, 39 degrees C) during the course of HCl-induced metabolic acidosis. The benefit of the change in both P50 on tissue oxygen tension was stu...

journal_title：Pediatric research

authors： Berthiaume Y,Bureau MA,Bégin R

更新日期：1981-05-01 00:00:00

abstract：:The influence of maternal stress during pregnancy on the postpartum iron status and immune maturation of infants was investigated in a nonhuman primate model. Forty infant rhesus monkeys were generated from two types of disturbed pregnancies, early or late gestation stress, and compared with 24 undisturbed controls. P...

journal_title：Pediatric research

authors： Coe CL,Lubach GR,Shirtcliff EA

更新日期：2007-05-01 00:00:00

abstract：:Neonatal group B streptococcal (GBS) sepsis produces pulmonary arterial hypertension and hypoxemia that are preventable by pretreatment with the selective thromboxane A2 synthase inhibitor, dazmegrel. In the present experiment we administered dazmegrel (8 mg/kg) 2 h after the initiation of a 2 1/2 h infusion of 5 X 10...

journal_title：Pediatric research

authors： Truog WE,Gibson RL,Juul SE,Henderson WR,Redding GJ

更新日期：1988-04-01 00:00:00

abstract：:We measured the cortisol and corticosterone responses to insulin-induced hypoglycemia in 13 growth hormone (GH)-deficient children and 30 short children without GH deficiency. Although there was no difference between the two groups in degree of hypoglycemia attained, baseline cortisol, baseline corticosterone, or cort...

journal_title：Pediatric research

authors： Chasalow FI,Blethen SL

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Encephalopathic neonates undergoing therapeutic hypothermia have increased risk for coagulopathy secondary to perinatal asphyxia and effects of cooling on the coagulation enzyme cascade. Thromboelastography (TEG) allows for a comprehensive assessment of coagulation that can be regulated for temperature. TEG ...

journal_title：Pediatric research

authors： Forman KR,Wong E,Gallagher M,McCarter R,Luban NL,Massaro AN

更新日期：2014-05-01 00:00:00

abstract：:Escherichia coli which elaborate heat stable enterotoxin (ST) are a major cause of endemic diarrhea in infants. The reason(s) for this increased susceptibility of infants to ST-mediated diarrhea is unknown. We investigated the possibility that the immature (14 and 21 day old) rat small intestine is more sensitive to S...

journal_title：Pediatric research

authors： Cohen MB,Moyer MS,Luttrell M,Giannella RA

更新日期：1986-06-01 00:00:00

abstract：:Hypoxic-ischemic injuries can evolve over several days, and recent studies suggest that further neuronal death may occur 6 to 72 h later. Because cerebral temperature is an important determinant of outcome during the primary injury, we investigated the effect of temperature, on outcome, during the later phases of inju...

journal_title：Pediatric research

authors： Sirimanne ES,Blumberg RM,Bossano D,Gunning M,Edwards AD,Gluckman PD,Williams CE

更新日期：1996-04-01 00:00:00

abstract：:BackgroundPost-hemorrhagic ventricular dilatation (PHVD) is predictive of mortality and morbidity among very-low-birth-weight preterm infants. Impaired cerebral blood flow (CBF) due to elevated intracranial pressure (ICP) is believed to be a contributing factor.MethodsA hyperspectral near-infrared spectroscopy (NIRS) ...

journal_title：Pediatric research

authors： McLachlan PJ,Kishimoto J,Diop M,Milej D,Lee DSC,de Ribaupierre S,St Lawrence K

更新日期：2017-10-01 00:00:00

abstract：:Early-onset neonatal group B beta-hemolytic streptococcus (GBS) infection exhibits pathophysiologic characteristics of a toxic shock syndrome, in which a cascade of inflammatory mediators are involved. Thromboxane A2 (TXA2) is thought to play an important role as a mediator of the pulmonary response to GBS toxin, beca...

journal_title：Pediatric research

authors： Sandberg K,Edberg KE,Fish W,Parker RA,Hellerqvist C,Sundell H

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:To investigate whether the YAP/TAZ (Yes-associated protein/transcriptional coactivator with PDZ binding motif) pathway contributes to the pathogenesis of lymphatic malformations (LMs). METHODS:YAP, TAZ, CTGF (connective tissue growth factor), and Ki-67 were detected in LMs by immunohistochemistry. The coloc...

journal_title：Pediatric research

authors： Zhong W,Jiang H,Zou Y,Ren J,Li Z,He K,Zhao J,Zhou X,Mou D,Cai Y

更新日期：2020-04-12 00:00:00

abstract：:The ontogenetic renal responsiveness to exogenous cortisol was examined in the chronically cannulated ovine fetus. The contribution of effects at proximal and distal tubule of the kidney were studied also. Cortisol (81.5 micrograms/h) was infused into immature ovine fetuses (mean gestational age -113.9 days) on five o...

journal_title：Pediatric research

authors： Towstoless MK,McDougall JG,Wintour EM

更新日期：1989-07-01 00:00:00

abstract：:The development of amniotic fluid turbidity during the third trimester is a known marker of fetal lung maturity. We hypothesized that this turbidity results from detachment of vernix caseosa from the fetal skin secondary to interaction with pulmonary-derived phospholipids in the amniotic fluid. To test this hypothesis...

journal_title：Pediatric research

authors： Narendran V,Wickett RR,Pickens WL,Hoath SB

更新日期：2000-07-01 00:00:00

abstract：:BackgroundPoor aerobic fitness is associated with worsening of asthma symptoms, and fitness training may improve asthma control. The mechanism linking fitness with asthma is not known. We hypothesized that repeated bouts of exercise would lead to a downregulation of glucocorticoid receptor (GR) expression on circulati...

journal_title：Pediatric research

authors： Lu KD,Cooper D,Haddad F,Zaldivar F,Kraft M,Radom-Aizik S

更新日期：2017-08-01 00:00:00

abstract：:Premature newborns are highly susceptible to severe bacterial infections. This is partially due to their immature innate immune system, characterized by decreased neutrophil and monocyte activity as well as by reduced concentrations of complement factors. However, additional mechanisms might be important for innate im...

journal_title：Pediatric research

authors： Förster-Waldl E,Sadeghi K,Tamandl D,Gerhold B,Hallwirth U,Rohrmeister K,Hayde M,Prusa AR,Herkner K,Boltz-Nitulescu G,Pollak A,Spittler A

更新日期：2005-07-01 00:00:00

abstract：:Newborn piglets exposed to acute hypoxia-ischemia (HI) received i.v. cannabidiol (HI + CBD) or vehicle (HI + VEH). In HI + VEH, 72 h post-HI brain activity as assessed by amplitude-integrated EEG (aEEG) had only recovered to 42 ± 9% of baseline, near-infrared spectroscopy (NIRS) parameters remained lower than normal, ...

journal_title：Pediatric research

authors： Lafuente H,Alvarez FJ,Pazos MR,Alvarez A,Rey-Santano MC,Mielgo V,Murgia-Esteve X,Hilario E,Martinez-Orgado J

更新日期：2011-09-01 00:00:00

abstract：:Bronchopulmonary dysplasia (BPD) is a common pulmonary complication in preterm infants that leads to fibrosis of the bronchoalveolar walls and often to severe clinical consequences. Type III collagen is deposited early in progressive fibrosis. Because the N-terminal propeptide of type III collagen (PIIINP), a by-produ...

journal_title：Pediatric research

authors： Heikinheimo M,Halila R,Marttinen E,Raivio K

更新日期：1992-04-01 00:00:00

abstract：:Kawasaki disease, which is characterized by systemic vasculitis causing coronary arterial involvement in childhood, shows a variety of immunoregulatory abnormalities. Especially the direct or indirect deleterious effects on endothelial cells of cytokines and anti-endothelial cell antibodies (AECA) are considered to be...

journal_title：Pediatric research

authors： Sakata K,Kita M,Imanishi J,Onouchi Z,Liu Y,Mitsui Y

更新日期：1995-10-01 00:00:00

abstract：:Cancer stem cells (CSC) are recently proposed to be the cancer initiating cells responsible for tumorigenesis and contribute to cancer resistance. Advances have been made in identifying and enriching CSC in leukemia and several solid tumors, including breast, brain and lung cancers. These studies suggest that, like no...

journal_title：Pediatric research

authors： Guo W,Lasky JL 3rd,Wu H

更新日期：2006-04-01 00:00:00

abstract：:Five enzymes were measured in 50 liver specimens (18 normal liver, 20 Reye liver, 12 diverse liver disorders other than Reye syndrome). The enzymes were: glutamic dehydrogenase (E.C. 1.4.1.3), monoamine oxidase (E.C. 1.4.3.4), lactate dehydrogenase (E.C. 1.1.1.27), D-glucose-6-phosphate dehydrogenase (E.C. 1.1.1.49), ...

journal_title：Pediatric research

authors： Mitchell RA,Arcinue EL,Partin JC,Partin JS,Ram ML,Chang CH,Smialek J,Sarnaik A

更新日期：1985-01-01 00:00:00

abstract：:A male child presented on the first day of life with metabolic acidosis with elevated blood lactate (15 mM), pyruvate (0.4 mM), and free fatty acid (1.3 mM) levels and a blood pH of 7.16. The severity of the acidosis was diminished by intravenous administration of glucose in large doses and by bicarbonate. On two occa...

journal_title：Pediatric research

authors： Robinson BH,Sherwood WG

更新日期：1975-12-01 00:00:00

abstract：OBJECTIVES:(1) Examine associations of a branched-chain amino acid (BCAA) metabolite pattern with metabolic risk across adolescence; (2) use Least Absolute Shrinkage and Selection Operator (LASSO) to identify novel metabolites of metabolic risk. METHODS:We used linear regression to examine associations of a BCAA score...

journal_title：Pediatric research

authors： Perng W,Tang L,Song PXK,Tellez-Rojo MM,Cantoral A,Peterson KE

更新日期：2019-02-01 00:00:00

abstract：:Increased expression of CD38 on CD8(+) T cells is associated with activation of the immune system, progression of HIV disease, and death in adults. The prognostic significance of these cells in HIV-infected children, where the picture is complicated by age-related differences in CD38 expression, remains controversial....

journal_title：Pediatric research

authors： Sherman GG,Scott LE,Galpin JS,Kuhn L,Tiemessen CT,Simmank K,Meddows-Taylor S,Meyers TM

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:The prevalence of vitamin D (vitD) deficiency presenting as rickets is increasing worldwide. Insufficient sun exposure, vitD administration, and/or calcium intake are the main causes. However, vitD system-related genes may also have a role. METHODS:Prospective study: 109 rachitic children completed a 6-mo s...

journal_title：Pediatric research

authors： El Kholy M,Elsedfy H,Fernández-Cancio M,Hamza RT,Amr NH,Ahmed AY,Toaima NN,Audí L

更新日期：2017-02-01 00:00:00