Abstract:
OBJECTIVES:The aim of this study was to investigate the bone regenerative properties of a heat treated cross-linked GBR membrane with zinc hydroxyapatite powders in the rat calvarial defect model over a 6-week period. MATERIAL AND METHODS:In vitro physio-chemical characterization involved X-ray diffraction analysis, surface topology by scanning electron microscopy, and zinc release studies in physiological buffers. Bilateral rat calvarial defects were used to compare the Zn-HAp membranes against the commercially available collagen membranes and the unfilled defect group through radiological and histological evaluation. RESULTS:The synthesized Zn-MEM (100 μm thick) showed no zinc ions released in the phosphate buffer solution (PBS) buffer, but zinc was observed under acidic conditions. At 6 weeks, both the micro-CT and histological analyses revealed that the Zn-MEM group yielded significantly greater bone formation with 80 ± 2% of bone filled, as compared with 60 ± 5% in the collagen membrane and 40 ± 2% in the unfilled control group. CONCLUSION:This study demonstrated the use of heat treatment as an alternative method to cross-linking the Zn-MEM to be applied as a GBR membrane. Its synthesis and production are relatively simple to fabricate, and the membrane had rough surface features on one side, which might be beneficial for cellular activities. In a rat calvarial defect model, it was shown that new bone formation was accelerated in comparison with the collagen membrane and the unfilled defect groups. These results would suggest that Zn-MEM has the potential for further development in dental applications.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Chou J,Komuro M,Hao J,Kuroda S,Hattori Y,Ben-Nissan B,Milthorpe B,Otsuka Mdoi
10.1111/clr.12520subject
Has Abstractpub_date
2016-03-01 00:00:00pages
354-60issue
3eissn
0905-7161issn
1600-0501journal_volume
27pub_type
杂志文章abstract::Bovine mineral spongiosa block (B-SB) was used as a bone substitute in sinus augmentation procedures in 10 consecutive patients. Implants were placed during the same session. The purpose of this study was to histopathologically examine the healing of the grafted site around the implants at 12 months. Radiographic foll...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130411.x
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:The placement of different graft materials and/or the use of occlusive membranes to cover the extraction socket entrance are techniques aimed at preserving/reducing alveolar ridge resorption. The use of grafting materials in fresh extraction sockets has, however, been questioned because particles of the graf...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1034/j.1600-0501.2003.00970.x
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVES:Collagen membranes are not limited to be occlusive barriers as they actively support bone regeneration. However, the impact of bone-derived growth factors on their osteoconductive competence has not been examined. METHODS:Twenty adult Sprague Dawley rats were included in the study. Calvaria defects with a d...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13133
更新日期:2018-04-01 00:00:00
abstract::The study aimed to examine the relationship between the subgingival flora around implants and their periodontal parameters. Plaque samples from 561 implants (279 patients) were analyzed by means of differential phase contrast microscopy and compared with the sample site's probing depth, bleeding tendency on probing, a...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1995.060401.x
更新日期:1995-12-01 00:00:00
abstract:AIM:To test whether an equine bone substitute block used for guided bone regeneration (GBR) of peri-implant defects differs from bovine block or particulate bone substitutes regarding the hard and soft tissue contours of the augmented ridge. MATERIAL & METHODS:Two semi-saddle bone defects were prepared in each side of...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13011
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:To assess the impact of collagen membrane application on bone formation surrounding implants placed simultaneously with the bone ring technique. MATERIAL AND METHODS:Dental implants were inserted simultaneously with the bone ring technique in standardized, vertical alveolar bony defects in the mandible of d...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13543
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:To determine attitudes of general dental practitioners in a community where provision dental implants is a well-known treatment modality; and to identify variations in the attitudes with respect to dentists' factors, training factors and implant provision factors. METHODS:A questionnaire survey to a random ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02537.x
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:To evaluate the potential influence of different cone-beam computed tomography (CBCT) devices on the transfer accuracy of an open-source system for computer-aided implantology (CAI). MATERIAL AND METHODS:A total of 108 implants in 18 partially edentulous patient-equivalent models were planned and fully guid...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02272.x
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:This study aimed to evaluate histologic and histomorphometric bone characteristics with a focus on vitality after lateral alveolar ridge augmentation using an autogenous bone graft as a block covered by either a platelet-rich fibrin (PRF) membrane (test group) or a standard procedure involving coverage of th...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13605
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to histologically compare the dynamics of bone healing response between calcium sulphate (CaS) and deproteinized bovine bone mineral (DBBM) particles in guided bone regeneration utilizing an extracellular matrix membrane (ECM) as barrier. MATERIALS AND METHODS:Eighteen rabbits were...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12425
更新日期:2015-05-01 00:00:00
abstract::Maxillary sinus floor augmentation with autogenous bone has become a widely accepted procedure in implant dentistry. The use of osteoconductive bone substitutes in this indication is controversial, since their use can lead to a prolonged healing time, inhomogenous ossification, foreign body reaction, migration of part...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1999.100609.x
更新日期:1999-12-01 00:00:00
abstract:AIM:Titanium dental implants are an important treatment option in the replacement of missing teeth. Implant failures can, however, occur and may be promoted by the loss of tissue as a result of local bacterial infection (peri-implantitis). OBJECTIVES:Bacterial adherence to implant surfaces is believed to be influenced...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2006.01274.x
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:This systematic review was initiated to explore the critical horizontal interproximal and buccal bone dimensions around implants for an optimal aesthetic outcome. MATERIALS AND METHODS:Pubmed, the Cochrane and the ISI web of Science databases were searched to identify eligible human studies that reflect on t...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2009.01782.x
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to evaluate and compare naturally occuring and ligature-induced peri-implantitis bone defects in humans and dogs. MATERIAL AND METHODS:Twenty-four partially and fully edentulous patients undergoing peri-implant bone augmentation procedures due to advanced peri-implant infect...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2006.01320.x
更新日期:2007-04-01 00:00:00
abstract::The aim of the present study was to evaluate the effect of augmenting the maxillary alveolar ridge and the lateral aspect of the mandible with onlay autogeneic cortico-cancellous bone grafts that were covered with e-PTFE membranes. The experiment was carried out in 51 rats. In 15 rats, the edentulous maxillary jaw bet...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130210.x
更新日期:2002-04-01 00:00:00
abstract::The purpose of this study was to investigate the possibility of antimicrobial treatment of peri-implant infections associated with a periodontitis-like subgingival microbiota. Nine partially or fully edentulous patients with titanium hollow cylinder implants were selected which showed loss of bone and probing depths >...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1992.030402.x
更新日期:1992-12-01 00:00:00
abstract::The purpose of this study was to compare the clinical and microbiological (microscopic) parameters during the development of experimental gingivitis and experimental peri-implant mucositis. Twenty partially edentulous patients were treated for moderate to advanced periodontal disease. Following active periodontal ther...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1994.050409.x
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of immortalized hypertrophic chondrocytes extracellular matrix (HCM) with or without the use of guided bone regeneration (GBR) on the healing of critical-size calvarial defects. MATERIAL AND METHODS:In 42 rats, 5 mm critical-size calvarial defects were surgically created. The animals ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02120.x
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the effect of topical applications of melatonin and apigenin (4',5,7-trihydroxyflavone) on new bone formation in post-extraction sockets after 30, 60 and 90 days. MATERIALS AND METHODS:Six American fox hounds were used in the study, extracting mandibular premolars (P2, P...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12866
更新日期:2018-11-01 00:00:00
abstract:AIM:The purpose of this in vitro study was to investigate the influence of degree of stiffness of implant-abutment connection of a Brånemark implant system on load- deflection ratios in three dimensions of the beam-end of a screw-retained stiff cantilever beam when subjected to vertically directed loads. MATERIAL AND ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02563.x
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:Zirconia powder in nanometers can be fabricated into inter-joined abutment of dental implant system with the injection shaping technique. This study was to detect the resistance of inter-joined zirconia abutment with different angle loading for clinical applications. MATERIALS AND METHODS:The inter-joined a...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02539.x
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:The aim of this prospective study was to evaluate the Nobel Direct and Nobel Perfect one-piece implants (OPIs) when used for immediate function. MATERIAL AND METHODS:Forty-eight patients were provided with 115 OPIs for loading with a provisional crown or a bridge within 24 h and followed for at least 12 mon...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01346.x
更新日期:2007-08-01 00:00:00
abstract:PURPOSE:To compare: (i) the incidence of soft tissue dehiscences; (ii) bone resorption before and after implant placement; and (iii) the survival and success rates of implants placed in two groups of patients with severe bone defects of the jaws reconstructed with autogenous onlay bone grafts alone (control group) or i...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02485.x
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Alumina-toughened zirconia (ATZ) is a possible alternative material to titanium for oral implants. No data are available on the fracture strength of ATZ oral implants. PURPOSE:The purpose of this study was to examine one-piece implants made of ATZ ceramic under artificial loading conditions and to compare t...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.01954.x
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVES:(1) To assess whether there is evidence of an association between the number of peri-implant tissue complications and patient characteristics such as gender, diabetes status, smoking status, and bite force; (2) To assess whether there is evidence of an association between the number of peri-implant tissue co...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12484
更新日期:2015-12-01 00:00:00
abstract:INTRODUCTION:Available literature suggests there is a transient drop in implant stability from approximately week 0 to week 3-4 as a result of peri-implant bone remodeling as it transitions from a primary, mechanical stability to a secondary, biological stability. Research investigating the influence of macro-thread de...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12945
更新日期:2017-10-01 00:00:00
abstract::Mandibular bone density, vertebral density and resorption of the edentulous ridge were correlated in a group of 17 partially edentulous subjects. Bone density was quantified by Quantitative Computerized Tomography; resorption was evaluated on panoramic radiographs. Mean bone density in dentate areas was significantly ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1999.100503.x
更新日期:1999-10-01 00:00:00
abstract:INTRODUCTION:Maxillary sinus augmentation is a predictable implant site development technique, although several local and systemic factors may influence outcomes. The aim of this study was to evaluate healing patterns and bone remodeling activity following the use of two different graft mixtures for maxillary sinus aug...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0501.2010.02073.x
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:During the fourth Summer Camp (SC) held by the European Association of Osseointegration (EAO), 20 junior representatives from various European and non-European universities and associations were selected to partake in oral presentation and communication skill development. AIMS:The aim of the EAO Summer Camp...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13625
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:The objectives of this systematic review were to assess the 5-year survival of resin-bonded bridges (RBBs) and to describe the incidence of technical and biological complications. METHODS:An electronic Medline search complemented by manual searching was conducted to identify prospective and retrospective co...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2007.01527.x
更新日期:2008-02-01 00:00:00