Abstract：
:The purpose of this study was to investigate the possibility of antimicrobial treatment of peri-implant infections associated with a periodontitis-like subgingival microbiota. Nine partially or fully edentulous patients with titanium hollow cylinder implants were selected which showed loss of bone and probing depths > or = 5 mm on one or several implants after at least 6 months following installation. They also yielded subgingival microbial samples with > or = 10(6) CFU/ml, including > or = 20% gram-negative anaerobic bacteria. The treatment included mechanical cleaning, irrigation of all peri-implant pockets > 3 mm with 0.5% chlorhexidine and systemic antimicrobial therapy (1000 mg ornidazole for 10 consecutive days). After therapy, bleeding scores decreased immediately and, over a one-year observation period, remained significantly lower than before treatment. A significant gradual reduction in mean probing depths was detected over this one-year period; only one case showed no improvement of local probing depth. Microbiological parameters indicated an instantaneous quantitative and qualitative change following treatment. Subsequently, several of these parameters tended to shift back towards pretreatment values. In the second half of the observation period, however, this tendency was reversed, and levels significantly different from baseline were eventually established. This study demonstrated that treatment aiming at reducing the subgingival bacterial mass and suppressing the anaerobic segment had a beneficial effect in patients suffering from peri-implantitis.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Mombelli A,Lang NPdoi
10.1034/j.1600-0501.1992.030402.xsubject
Has Abstractpub_date
1992-12-01 00:00:00pages
162-8issue
4eissn
0905-7161issn
1600-0501journal_volume
3pub_type
杂志文章abstract：:The aim of this study was to investigate whether a new connective tissue attachment can occur on a surface of hydroxyapatite (HA) when periodontal ligament (PDL)-derived cells with the ability to form new connective tissue attachment are allowed to populate the surface of HA. Six maxillary canines from 3 cats were use...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.1993.040303.x
更新日期：1993-09-01 00:00:00
abstract：:A clinical and radiographical study was performed to evaluate the treatment outcome of single tooth replacements with artificial crowns retained to implants installed according to a 1-stage surgical procedure and immediate loading (Experimental Group = EG) in comparison to the original 2-stage concept (Control Group =...
journal_title：Clinical oral implants research
pub_type： 临床试验,杂志文章
doi：10.1034/j.1600-0501.2000.011001026.x
更新日期：2000-02-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the effect of scan mode of the cone beam computed tomography (CBCT) in the preoperative dental implant measurements. MATERIAL AND METHODS:Completely edentulous mandibles with entirely resorbed alveolar processes were selected for this study. Five regions were selected (i...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/clr.12080
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:There are various alternatives for the management of oral conditions that may lead to or already have lead to partial or full edentulism. Economic evaluations measure the efficiency of alternative healthcare interventions and provide useful information for decision-making and the allocation of scarce resource...
journal_title：Clinical oral implants research
pub_type： 共识发展会议,杂志文章,评审
doi：10.1111/clr.12630
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVES:Compare clinical outcomes of two types of dental implants with non-matching implant-abutment junctions loaded with fixed implant-borne reconstructions at 5 years of loading. MATERIALS AND METHODS:In 64 patients, one of two implant systems (S1, S2) was randomly used to support fixed dental prostheses (FDP). ...
journal_title：Clinical oral implants research
pub_type： 杂志文章,随机对照试验
doi：10.1111/clr.13526
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVES:Electrospun cotton wool-like nanocomposite (ECWN) is a novel synthetic bone substitute that incorporates amorphous calcium phosphate nanoparticles into a biodegradable synthetic copolymer poly(lactide-co-glycolide). The objectives of this study were to develop a tooth extraction socket model in sheep for bon...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/clr.12673
更新日期：2016-07-01 00:00:00
abstract：:Non-submerged ITI Bonefit implants (ITI Dental Implant System) were inserted in edentulous lower jaws of 46 patients. The patients were provided with either a fixed prosthesis or an overdenture, and has been followed during a 2-year-period. At the 1-year examination, the suprastructures were removed permitting test of...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.1996.070406.x
更新日期：1996-12-01 00:00:00
abstract：OBJECTIVES:Diabetes mellitus is currently classified as a relative contraindication for implant treatment because of microangiopathies with the consequence of impaired bone regeneration and higher rates of implant failure. The study aim was to investigate peri-implant bone formation in a diabetic animal model in compar...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2011.02380.x
更新日期：2013-02-01 00:00:00
abstract：OBJECTIVES:To investigate the role of different levels of pH of artificial saliva under simulated oral environment on the corrosion behavior of commercially pure titanium (cp-Ti) and Ti-6Al-4V alloy. Special attention is given to understand the changes in corrosion kinetics and surface characterization of Ti by using e...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2011.02265.x
更新日期：2012-09-01 00:00:00
abstract：OBJECTIVES:To evaluate the effect of immortalized hypertrophic chondrocytes extracellular matrix (HCM) with or without the use of guided bone regeneration (GBR) on the healing of critical-size calvarial defects. MATERIAL AND METHODS:In 42 rats, 5 mm critical-size calvarial defects were surgically created. The animals ...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2010.02120.x
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVE:Estimate changes in augmentation height and volume after lateral guided bone regeneration (GBR) augmentation with different ratios of deproteinized bovine bone mineral (DBBM) and particulate autogenous bone (PAB) and autogenous bone block (ABB), at different time points. MATERIAL AND METHODS:Twenty-four mini...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/clr.13687
更新日期：2020-11-20 00:00:00
abstract：AIM:This study compared the effects of Escherichia-coli-produced recombinant human bone morphogenetic protein 2 (ErhBMP-2) with a biphasic calcium phosphate (BCP) carrier to those of deproteinized bovine bone in human maxillary sinus floor augmentation. MATERIAL AND METHODS:Screening for this clinical trial selected 5...
journal_title：Clinical oral implants research
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/clr.12471
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:To analyze the outcomes of static computer-aided implant placement (sCAIP) compared to partially guided (PGIP) and free-handed (FHIP) implant placement. MATERIAL AND METHODS:This study was registered in PROSPERO (CRD42019131397). A comprehensive literature search was performed by two independent examiners. O...
journal_title：Clinical oral implants research
pub_type： 杂志文章,meta分析
doi：10.1111/clr.13635
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVES:(1) To assess whether there is evidence of an association between the number of peri-implant tissue complications and patient characteristics such as gender, diabetes status, smoking status, and bite force; (2) To assess whether there is evidence of an association between the number of peri-implant tissue co...
journal_title：Clinical oral implants research
pub_type： 杂志文章,随机对照试验
doi：10.1111/clr.12484
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVES:To evaluate the effect of vertical and periosteal-releasing incisions (PRI) on the extension of the buccal flap in a trapezoidal flap design. MATERIAL AND METHODS:Thirty patients scheduled for implant surgery accompanied by bone augmentation were recruited. The amount of flap extension pulled with a minimal...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2011.02244.x
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVES:This study evaluated the influence of oestrogen deficiency and its therapies on bone tissue around osseointegrated implants. METHODS:Implants were placed in 66 female rats tibiae. The animals were assigned into five groups: control (CTL), sham, ovariectomy (OVX), oestrogen (EST), and alendronate (ALE). Whil...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2010.01989.x
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVES:To compare the effectiveness of free-handed (FH), pilot-drill guided (PG) and fully guided (FG) implant surgery by means of the apical global deviation (AGD) in relation to the additional financial cost and time spent. MATERIALS AND METHODS:Thirty-three partially edentulous patients in need of ≥2 implants i...
journal_title：Clinical oral implants research
pub_type： 杂志文章,随机对照试验
doi：10.1111/clr.13399
更新日期：2019-02-01 00:00:00
abstract：:The aim of this study was to determine the cell characteristics that regulate implant osseointegration. The heterogeneity of bone marrow stromal cells obtained from 11 donors was assessed by measuring the expression of a large panel of adhesion molecules. Large differences in expression of adhesion molecules were dete...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.2003.00949.x
更新日期：2003-10-01 00:00:00
abstract：:The objective of the present investigation was to characterize the cellular composition of the soft tissues surrounding consecutively retrieved late failures of Brånemark implants. Criteria for implant failure were signs of loss of osseointegration (radiographic peri-fixtural radiolucency and mobility). The clinical h...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.1997.080502.x
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:Graft consolidation follows a gradient that reflects the properties of bone substitutes at sites of sinus augmentation. Here we present an analytical method to investigate the process of graft consolidation taking the distance from the maxillary host bone into account. MATERIAL AND METHODS:We therefore evalu...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2009.01733.x
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVE:Crestal bone loss around dental implants is a criterion for success as this could prevent loss of implant and superstructure. The macrogeometry of the implant could influence bone remodelling when the implant-abutment connection is placed at crestal bone level or above. The aim of this study was to evaluate c...
journal_title：Clinical oral implants research
pub_type： 杂志文章,随机对照试验
doi：10.1111/clr.12581
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVES:To compare the effect of two surgical techniques, lateral condensation and bone drilling, on changes in temperature of the adjacent low-density bone during implant placement into posterior maxilla and to investigate the influence of the host factors - age, gender, region of implantation, bone density, and th...
journal_title：Clinical oral implants research
pub_type： 杂志文章,随机对照试验
doi：10.1111/clr.12191
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND:Different therapeutic concepts and methods have been proposed for improving dental implant outcomes in three specific clinical situations: (i) the fresh extraction socket with alveolar ridge preservation protocols; (ii) the posterior maxilla with limited bone height with either the placement of regular-sized...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/clr.12674
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:After implant insertion and loading, crestal bone usually undergoes remodeling and resorption. If the horizontal relationship between the outer edge of the implant and a smaller-diameter component ('platform switching') is altered, there seems to be reduced crestal bone loss. Immediate loading allows immedia...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2007.01449.x
更新日期：2008-03-01 00:00:00
abstract：:Maxillary sinus floor augmentation with autogenous bone has become a widely accepted procedure in implant dentistry. The use of osteoconductive bone substitutes in this indication is controversial, since their use can lead to a prolonged healing time, inhomogenous ossification, foreign body reaction, migration of part...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.1999.100609.x
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to radiologically and histologically evaluate the graft healing and volumetric changes after lateral augmentation with two different compositions of deproteinized bovine bone (DPBB) and autogenous bone (AB). MATERIAL AND METHODS:Thirteen patients with a mean age of 59.6 ± 12.1 years ...
journal_title：Clinical oral implants research
pub_type： 杂志文章,随机对照试验
doi：10.1111/clr.12143
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVES:The aim of this prospective study was to evaluate the 5-year performance and success rate of titanium screw-type implants with the titanium plasma spray (TPS) or the sand-blasted, large grit, acid-etched (SLA) surface inserted in a two-stage sinus floor elevation (SFE) procedure in the posterior maxilla. MA...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2008.01573.x
更新日期：2008-10-01 00:00:00
abstract：:The aim of this study was to investigate the effect of calcium phosphate coating crystallinity and composition on the proliferation and differentiation of rat bone marrow (RBM) cells. Grit-blasted titanium substrates were provided with thin sputter-coated calcium phosphate (Ca-P) films of different composition. The Ca...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.2003.00886.x
更新日期：2003-08-01 00:00:00
abstract：OBJECTIVES:The aim of this prospective pilot study was to evaluate the prosthodontic maintenance as well as the implant outcome of single implant-retained mandibular overdentures over an observation period of 6 years. METHODS:Eleven edentulous patients received one single implant in the midline of the mandible. Dentur...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/clr.12427
更新日期：2015-10-01 00:00:00
abstract：OBJECTIVE:Using computed tomography, to compare vertical and volumetric bone augmentation after interposition grafting with bovine bone mineral matrix (GEISTLICH BIO-OSS® ) or hydroxyapatite/tricalcium phosphate (STRAUMANN® BONECERAMIC) for atrophic posterior mandible reconstruction through segmental osteotomy. MATERI...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/clr.12985
更新日期：2017-10-01 00:00:00
