Abstract:
OBJECTIVES:This study evaluated the influence of oestrogen deficiency and its therapies on bone tissue around osseointegrated implants. METHODS:Implants were placed in 66 female rats tibiae. The animals were assigned into five groups: control (CTL), sham, ovariectomy (OVX), oestrogen (EST), and alendronate (ALE). While CTL was sacrificed 60 days after implant placement, other groups were subjected to ovariectomy or sham surgery according to group and euthanized after 90 days. Blood and urine samples were collected at sacrifice day for osteocalcin (OCN) and deoxypyridinoline (DPD) quantification. Densitometry of femur and lumbar vertebrae was performed in order to evaluate rats' skeletal impairment. Non-decalcified sections were referred to fluorescent and light microscopy for analyses of mineral apposition rate (MAR), eroded and osteoclastic surfaces, bone-to-implant contact (BIC), and bone area fraction occupancy (BAFO). RESULTS:Results from the OVX group showed significantly lower bone mineral density (BMD), BIC, BAFO, and MAR, while OCN, deoxipiridinoline, eroded surface and ostecoclastic surface were increased compared with the other groups of the study. ALE reduced OCN and DPD concentrations, MAR, osteoclastic and eroded surfaces, and no difference was in BIC and BAFO relative to SHAM. EST and CTL showed similar results to SHAM for measurements. CONCLUSIONS:Oestrogen deficiency exerted a negative influence on bone tissue around implants, while oestrogen replacement therapy and alendronate were effective against its effects. Although alendronate therapy maintained the quantity of bone around implants, studies evaluating bone turnover kinetics are warranted.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Giro G,Coelho PG,Pereira RM,Jorgetti V,Marcantonio E Jr,Orrico SRdoi
10.1111/j.1600-0501.2010.01989.xsubject
Has Abstractpub_date
2011-03-01 00:00:00pages
259-64issue
3eissn
0905-7161issn
1600-0501journal_volume
22pub_type
杂志文章abstract:OBJECTIVES:The goal of this study was to enhance the blood responses to titanium (Ti) surfaces used for dental implant application through the formation of a TiO2 nano-mesh surface layer produced by a fast electrochemical anodization treatment. MATERIAL AND METHODS:Electrochemical anodization treatments with different...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02152.x
更新日期:2012-03-01 00:00:00
abstract::Four different surface modifications were designed. Forty screw-shaped implants were divided into 4 groups, 10 screws in each. Every screw was prepared with 2 different surface topographies. The surface topography was measured with a confocal laser scanning profilometer and the surface roughness was characterized usin...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1998.090102.x
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVES:This study aimed at evaluating the biological response of titanium implants coated with UV-irradiated 7-dehydrocholesterol (7-DHC) and vitamin E (VitE) in vivo and analyzing the effects of aging on their stability and bioactivity in vitro. MATERIAL AND METHODS:Titanium surfaces were coated with 7-DHC and Vi...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12815
更新日期:2017-04-01 00:00:00
abstract::The objective of the present investigation was to characterize the cellular composition of the soft tissues surrounding consecutively retrieved late failures of Brånemark implants. Criteria for implant failure were signs of loss of osseointegration (radiographic peri-fixtural radiolucency and mobility). The clinical h...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1997.080502.x
更新日期:1997-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to test the retention of metal copings fabricated to fit on the one-groove, one flat-sided solid titanium abutment using six different cements. MATERIALS AND METHODS:Ten hollow screw 3.8 mm ITI implants were mounted in acrylic resin blocks. A solid titanium abutment was placed o...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130401.x
更新日期:2002-08-01 00:00:00
abstract::The information concerning the molecular events taking place in onlay bone grafts are still incipient. The objective of the present study is to correlate the effects of perforation of resident bone bed on (1) the timing of onlay autogenous graft revascularization; (2) the maintenance of volume/density of the graft (as...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01485.x
更新日期:2008-04-01 00:00:00
abstract::The purpose of this study was to compare the clinical and microbiological (microscopic) parameters during the development of experimental gingivitis and experimental peri-implant mucositis. Twenty partially edentulous patients were treated for moderate to advanced periodontal disease. Following active periodontal ther...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1994.050409.x
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVE:Using computed tomography, to compare vertical and volumetric bone augmentation after interposition grafting with bovine bone mineral matrix (GEISTLICH BIO-OSS® ) or hydroxyapatite/tricalcium phosphate (STRAUMANN® BONECERAMIC) for atrophic posterior mandible reconstruction through segmental osteotomy. MATERI...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12985
更新日期:2017-10-01 00:00:00
abstract:UNLABELLED:To evaluate volumetric changes (VC) of pontic sites with or without soft tissue grafting over 5 years. MATERIAL AND METHODS:Twelve patients participating in a prospective clinical trial evaluating fixed dental prostheses (FDPs) were selected on the basis of having received a subepithelial connective tissue ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12743
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:A precise and scientifically established method for the evaluation of the bone quality/primary stability is the measure of the insertion torque (IT). The aim of this study was a comparison between the IT values and the bone-implant contact percentage (BIC) of human implants retrieved after a 4/8-week healing ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01599.x
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to radiologically and histologically evaluate the graft healing and volumetric changes after lateral augmentation with two different compositions of deproteinized bovine bone (DPBB) and autogenous bone (AB). MATERIAL AND METHODS:Thirteen patients with a mean age of 59.6 ± 12.1 years ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12143
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVES:The objectives of this systematic review were to assess the 5-year survival of resin-bonded bridges (RBBs) and to describe the incidence of technical and biological complications. METHODS:An electronic Medline search complemented by manual searching was conducted to identify prospective and retrospective co...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2007.01527.x
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVES:This prospective clinical study investigates long-term survival and clinical parameters of non-submerged implants with large buccal dehiscences treated with a deproteinized bovine bone mineral xenograft and a non-resorbable membrane in a one-stage approach. MATERIAL AND METHODS:Sixteen consecutive non-subme...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01154.x
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVES:To analyze the relationships between peri-implant conditions and periodontal conditions in Chinese patients with dental implants in place for at least 1 year. MATERIAL AND METHODS:Seventy-six patients (mean age, 41 ± 10 years; range, 21-69 years) who received placement of 120 dental implants (Straumann(®) )...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12114
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:A systematic review and meta-analysis are carried out to assess the scientific evidence that bisphosphonate therapy can decrease the success rate of dental implants. MATERIAL AND METHODS:The PubMed (Medline) database was used to search for articles published up until February 22, 2014. The meta-analysis was ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,meta分析,评审
doi:10.1111/clr.12526
更新日期:2016-02-01 00:00:00
abstract::The presence of certain glycosaminoglycans in peri-implant sulcus fluid may be an effective means of monitoring changes in bone metabolic activity following initial loading of implant abutments. This study has investigated levels of chondroitin 4 sulphate and hyaluronan in peri-implant sulcus fluid from titanium osseo...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1991.020404.x
更新日期:1991-10-01 00:00:00
abstract::The present study describes the use of a degradable and a non-degradable material for guided bone regeneration. Forty rabbits were divided into 5 groups. Bicortical defects 15 mm in diameter were prepared in rabbit calvaria. A titanium microplate was placed over the defect to prevent collapse of the membrane. The calv...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1998.090504.x
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this prospective study was to evaluate one-stage dental implants clinically and radiographically after 10 years in function. MATERIAL AND METHODS:Twenty-five patients with a total of 68 implants [46 hollow screws (HS) and 22 hollow cylinders (HC)] who previously participated in 5-year prospect...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01479.x
更新日期:2008-03-01 00:00:00
abstract:AIM:To spectrophotometrically and visually test whether the peri-implant mucosal color differs from the color of the natural gingiva. MATERIAL AND METHODS:Forty single implants in the incisor and premolar region of 40 patients were assessed 3-7 years after implant placement. The differences of the color components lig...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12781
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVES:To analyze clinical, esthetic, radiographic, and prosthetic outcomes of implants and implant-supported reconstructions using two types of dental implants with non-matching implant abutment junctions. MATERIALS AND METHODS:A total of 64 patients in need of dental implant therapy with fixed reconstructions we...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12721
更新日期:2016-09-01 00:00:00
abstract::The aim of the present study was to evaluate the effect of augmenting the maxillary alveolar ridge and the lateral aspect of the mandible with onlay autogeneic cortico-cancellous bone grafts that were covered with e-PTFE membranes. The experiment was carried out in 51 rats. In 15 rats, the edentulous maxillary jaw bet...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130210.x
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to histologically compare the dynamics of bone healing response between calcium sulphate (CaS) and deproteinized bovine bone mineral (DBBM) particles in guided bone regeneration utilizing an extracellular matrix membrane (ECM) as barrier. MATERIALS AND METHODS:Eighteen rabbits were...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12425
更新日期:2015-05-01 00:00:00
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journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13300
更新日期:2018-10-01 00:00:00
abstract::This paper reports on a 7-year life table analysis on ITI titanium plasma-sprayed (TPS) and sandblasted and etched (SLA) implants placed in a private practice and loaded for at least 1 year. In 236 patients, 528 (264 TPS and 264 SLA) implants were placed, 351 (66.5%) implants rehabilitated the posterior region and 71....
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.00978.x
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVE:To assess the influence of a collagen membrane placed subjacent to a pristine sinus mucosa on the healing outcome of a sinus floor elevation procedure. MATERIALS AND METHODS:Eight Pelibuey sheep (Cubano rojo) underwent sinus floor elevation on both sides of the maxilla. At a randomly selected side (test), a ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12762
更新日期:2016-11-01 00:00:00
abstract::This study aimed to investigate the effect of hyperbaric oxygen (HBO) therapy on the tissue reactions to commercially pure (c.p.) titanium implants placed in free autogenous bone graft by a 1-stage procedure. Eighty c.p. titanium implants were placed in the bone grafted from iliac crest to bilateral mandible of 40 Jap...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1996.090604.x
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVES:The aim of this investigation was to evaluate histologically, histometrically, and histomorphometrically the influence of plaque accumulation on the peri-implant hard tissues. MATERIAL AND METHODS:Twelve fully edentulous subjects were selected for this investigation. Four to five standard titanium screw imp...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-0501.2003.00849.x
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:After implant insertion and loading, crestal bone usually undergoes remodeling and resorption. If the horizontal relationship between the outer edge of the implant and a smaller-diameter component ('platform switching') is altered, there seems to be reduced crestal bone loss. Immediate loading allows immedia...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01449.x
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:The aim was to investigate histomorphometrically whether or not implant surface nanotopography improves the bone response under immediate loading simultaneous to sinus grafting. MATERIALS AND METHODS:Dual acid-etched titanium microimplants with/without crystalline surface deposition of calcium phosphate part...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02398.x
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to investigate the relationships among reported methodological, statistical, clinical and paratextual variables of randomized clinical trials (RCTs) in implant therapy, and their influence on subsequent research. MATERIALS AND METHODS:The material consisted of the RCTs in im...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01350.x
更新日期:2007-08-01 00:00:00