Abstract:
BACKGROUND:The placement of different graft materials and/or the use of occlusive membranes to cover the extraction socket entrance are techniques aimed at preserving/reducing alveolar ridge resorption. The use of grafting materials in fresh extraction sockets has, however, been questioned because particles of the grafted material have been found in alveolar sockets 6-9 months following their insertion. AIM:The aims of the study were to (i). evaluate whether alveolar ridge resorption following tooth extraction could be prevented or reduced by the application of a bioabsorbable polylactide-polyglycolide sponge used as a space filler, compared to natural healing by clot formation, and (ii). evaluate histologically the amount and quality of bone tissue formed in the sockets, 6 months after the use of the bioabsorbable material. MATERIAL AND METHODS:Thirty-six patients, undergoing periodontal therapy, participated in this study. All patients were scheduled for extraction of one or more compromised teeth. Following elevation of full-thickness flaps and extraction of teeth, measurements were taken to evaluate the distance between three landmarks (mesio-buccal, mid-buccal, disto-buccal) on individually prefabricated stents, and the alveolar crest. Twenty-six alveolar sockets (test) were filled with a bioabsorbable polylactide-polyglycolide acid sponge (Fisiograft), while 13 sockets (controls) were allowed to heal without any filling material. The flaps were sutured with no attempt to achieve primary closure of the surgical wound. Re-entry for implant surgery was performed 6 months following the extractions. Thirteen biopsies (10 test and three control sites) were harvested from the sites scheduled for implant placement. RESULTS:The clinical measurements at 6 months revealed, in the mesial-buccal site, a loss of bone height of 0.2 mm (1.4 SD) in the test and 0.6 mm (1.1 SD) in the controls; in the mid-buccal portion a gain of 1.3 mm (1.9 SD) in the test and a loss of 0.8 mm (1.6 SD) in the controls; and in the distal portion a loss of 0.1 mm (1.1 SD) in the test and of 0.8 (1.5 SD) mm in the controls. The biopsies harvested from the test sites revealed that the new bone formed at 6 months was mineralized, mature and well structured. Particles of the grafted material could not be identified in any of the 10 test biopsies. The bone formed in the control sites was also mature and well structured. CONCLUSION:The results of this study indicate that alveolar bone resorption following tooth extraction may be prevented or reduced by the use of a bioabsorbable synthetic sponge of polylactide-polyglycolide acid. The quality of bone formed seemed to be optimal for dental implant insertion.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Serino G,Biancu S,Iezzi G,Piattelli Adoi
10.1034/j.1600-0501.2003.00970.xsubject
Has Abstractpub_date
2003-10-01 00:00:00pages
651-8issue
5eissn
0905-7161issn
1600-0501pii
970journal_volume
14pub_type
临床试验,杂志文章abstract:OBJECTIVE:The purpose of this prospective study was to evaluate one-stage dental implants clinically and radiographically after 10 years in function. MATERIAL AND METHODS:Twenty-five patients with a total of 68 implants [46 hollow screws (HS) and 22 hollow cylinders (HC)] who previously participated in 5-year prospect...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01479.x
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVES:The objective was to evaluate the association between peri-implant bleeding on probing (BoP) and probing depth. Other factors regarding patients, implants, and sites were taken into consideration. MATERIAL AND METHODS:Consecutive adult patients with ≥1 dental implant were eligible. Two calibrated operators ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13001
更新日期:2017-11-01 00:00:00
abstract::This study compared osteoblasts proliferation, differentiation, and protein synthesis on new and used titanium (Ti) disks to test the hypothesis that cleaning and resterilization of previously used Ti disks does not alter cell response to a particular surface. Ti disks of varying roughness were prepared by one of five...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1996.070104.x
更新日期:1996-03-01 00:00:00
abstract::We tested in a randomized controlled clinical trial the effect of pain and instability of dentures on bite force with different degrees of mucosal support. The trial involved 3 groups who had received: 1) a new conventional denture (CD-group), 2) an implant-mucosa-borne overdenture on 2 IMZ implants (IMZ-group) or 3) ...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-0501.2001.012001046.x
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVES:This study aimed to determine bone level changes after 5-6 years of follow-up for a large group of one-stage dental implants consecutively placed in private practice. Potential confounding factors influencing crestal bone loss (CBL) were also assessed. MATERIALS AND METHODS:A total of 378 transmucosal Strau...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12083
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:Using computed tomography, to compare vertical and volumetric bone augmentation after interposition grafting with bovine bone mineral matrix (GEISTLICH BIO-OSS® ) or hydroxyapatite/tricalcium phosphate (STRAUMANN® BONECERAMIC) for atrophic posterior mandible reconstruction through segmental osteotomy. MATERI...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12985
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:Graft consolidation follows a gradient that reflects the properties of bone substitutes at sites of sinus augmentation. Here we present an analytical method to investigate the process of graft consolidation taking the distance from the maxillary host bone into account. MATERIAL AND METHODS:We therefore evalu...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2009.01733.x
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVES:In regenerative medicine, surface engineering of bioinert synthetic materials is often required in order to introduce bioactive species that can promote cell adhesion, proliferation, viability and enhanced ECM-secretion functions. The aim of this work is to study cell interaction with alumina-modified surfac...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01642.x
更新日期:2009-03-01 00:00:00
abstract::For certain surgical procedures (e.g. placement of implants), an accurate localisation of the mandibular canal is of utmost importance to avoid injuries to the neurovascular bundle. The aim of the present study was to evaluate, on human fresh cadavers (n = 6), the accuracy of conventional spiral tomography for the loc...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2001.012003230.x
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND/AIMS:Clinical probing of the soft tissues around oral implants has become a frequently used parameter for clinical monitoring. However, the healing of the disruption of the soft tissue seal as a result of probing has not yet been studied. The purpose of this study was to evaluate the healing events in the pe...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130601.x
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:Non-surgical mechanical therapy of peri-implantitis (PI) with/without adjunctive measures yields limited clinical improvements. AIM:To evaluate the clinical outcomes following non-surgical mechanical therapy of PI with adjunctive application of a diode laser after an observation period ≥2 years. MATERIAL A...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12689
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:This retrospective cross-sectional study aimed to evaluate the prevalence of biologic complications of implants in patients treated by fixed implant supported prosthesis without regular maintenance program. MATERIALS AND METHODS:One hundred thirty-four patients with 478 implants, installed during a 10-year ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12800
更新日期:2017-03-01 00:00:00
abstract::This paper describes a surgical technique that permits the achievement of bilateral simultaneous augmentation of the maxillary sinus floor with the use of autologous bone harvested from the mandibular symphysis alone. Out of a group of 26 partially edentulous patients consecutively treated for sinus augmentation in an...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2003.140210.x
更新日期:2003-04-01 00:00:00
abstract::The present paper describes the clinical and radiographic healing results of 27 implants followed from 1 to 3 years after functional implant loading. Prior to implant placement, alveolar ridges with insufficient bone volume were augmented using autogenous bone grafts and a micro titanium mesh for graft stabilization. ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1998.090208.x
更新日期:1998-04-01 00:00:00
abstract::The aim of this study was to evaluate the soft tissue conditions at osseo-integrated oral implants in relation to the width of masticatory mucosa. Thirty-nine patients who had received a full-arch fixed bridge reconstruction > or = 10 years ago or a partial reconstruction > or = 5 years ago on a total of 171 implants ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1994.050101.x
更新日期:1994-03-01 00:00:00
abstract:OBJECTIVES:As biomaterial-induced modulation of mediators of the immune response may be a potential therapeutic approach to enhance wound healing events, the aim of this study was to delineate the effects of titanium surface modification on macrophage phenotype and function. MATERIAL AND METHODS:Rodent bone marrow-der...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13522
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:An animal study was carried out to investigate the influence of platelet-rich plasma (PRP) on the regeneration of bony defects. MATERIAL AND METHODS:Critical-size defects in the forehead region of a mini-pig were filled with randomly distributed combinations of autogenous bone, tricalcium-phosphate granules...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.00980.x
更新日期:2004-04-01 00:00:00
abstract::Sinus augmentation has been advocated to be a surgical technique with predictable results in peri-implant surgery. Endoscopic surgery of the maxillary sinus so far has been used as diagnostic procedure. In this paper, the use of endoscopy is described as a low invasive adjunctive technique in sinus floor augmentation....
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1997.080612.x
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVES:The objectives of this systematic review were to assess the 5-year survival of resin-bonded bridges (RBBs) and to describe the incidence of technical and biological complications. METHODS:An electronic Medline search complemented by manual searching was conducted to identify prospective and retrospective co...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2007.01527.x
更新日期:2008-02-01 00:00:00
abstract::This review article provides an overview of cone beam (CB) imaging technology and its role in orofacial imaging, including comparison with two-dimensional (2D) radiography and multislice computed tomography (MCT). The radiation dose levels of CB systems are discussed, with reference to those delivered by MCT and commo...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2010.01996.x
更新日期:2010-11-01 00:00:00
abstract::The aim of the present study was to evaluate the soft tissue response to intra-orally exposed and contaminated titanium surfaces (machined, blasted or polished) after being chemically and/or mechanically cleaned. Eight adult Sprague-Dawley rats were used for histomorphometrical and histological analyses. A total of 44...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2000.011004370.x
更新日期:2000-08-01 00:00:00
abstract:AIM:To evaluate surface roughness alterations at the smooth neck of dental implants after the use of eight different prophylactic procedures. MATERIALS AND METHODS:50 tissue level implants (Institut Straumann AG, Basel, Switzerland) were used for the present investigation. The smooth collar of each implant was divided...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12849
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVES:The goal of this study was to enhance the blood responses to titanium (Ti) surfaces used for dental implant application through the formation of a TiO2 nano-mesh surface layer produced by a fast electrochemical anodization treatment. MATERIAL AND METHODS:Electrochemical anodization treatments with different...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02152.x
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION:Immediate functional loading of dental implants for full-arch restoration is a patient-friendly approach, shown to be feasible with a good long-term prognosis in a completely edentulous mandible. For the complete restoration of the maxilla, acceptable long-term clinical follow-up is lacking or based on cas...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0501.2008.01586.x
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES:To assess the bleeding on probing (BOP) tendency and periodontal probe penetration when applying various probing forces at implant sites in patients with a high standard of oral hygiene with well-maintained peri-implant tissues. MATERIAL AND METHODS:Seventeen healthy patients with excellent oral hygiene in ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0501.2008.01601.x
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:Despite the high success rates of endosseous oral implants, restrictions have been advocated to their placement with regard to the bone available in height and volume. The use of short or nonstandard-diameter implants could be one way to overcome this limitation. MATERIAL AND METHODS:In order to explore t...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2006.01349.x
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVES:The present study aimed at evaluating the marginal bone resorption and the peri-implant tissue conditions around Narrow-Neck ITI implants in the implant-prosthetic treatment of the agenesis of maxillary lateral incisors. MATERIAL AND METHODS:Thirty patients affected by monolateral or bilateral agenesis of t...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0501.2005.01188.x
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:In the present study, a new healing cap that could generate a pulsed electromagnetic field (PEMF) around titanium implants to stimulate peri-implant osteogenesis was tested in the rabbit model. MATERIALS AND METHODS:A total of 22 implants were inserted in the proximal tibial metaphysis of 22 rabbits. A heali...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12661
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:To assess the relationship between smooth and roughened implant surfaces of straight and narrow configurations with respect to microdamage of the bone surface during placement of dental implants. MATERIALS AND METHODS:Straight and tapered, rough and smooth surface Nobel Biocare implants were placed into she...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02024.x
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:Protocols of immediate loading have been reported in several studies. It has also been demonstrated that the cause of failure of immediate loaded implants is due to the micromotion on the bone-implant interface induced by immediate loading. There should be a minimum gap between the implant and the peri-impla...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02036.x
更新日期:2011-05-01 00:00:00