Abstract:
OBJECTIVES:An animal study was carried out to investigate the influence of platelet-rich plasma (PRP) on the regeneration of bony defects. MATERIAL AND METHODS:Critical-size defects in the forehead region of a mini-pig were filled with randomly distributed combinations of autogenous bone, tricalcium-phosphate granules (CeraSorb), bovine spongious blocks (BioOss) and a bovine bone inducing collagenous sponge (Colloss) with and without PRP in two preparations (Cusasan, 3i). The animals were killed after 2, 4 and 12 weeks. The specimens were evaluated microradiographically and immunohistologically. RESULTS:Autologous bone (38 +/- 9.9%) and Colloss (52.6 +/- 4.0%) showed the highest remineralization rates at 2 weeks. The initial high expression of BMP-2 in the Colloss-group gives evidence of an early initiation of bony regeneration. At 2 weeks PRP ad modum 3i was able to enhance bone healing significantly (P=0.028) only when applied in combination with autogenous bone (62.8 +/- 1.6%). Four weeks after surgery, both PRP preparations did no longer increase bony regeneration in the autogenous groups. The osteoconductive effect of Bio-Oss (38.7 +/- 5.5%) and CeraSorb (41+/-4.9%) was remarkable as well 4 weeks after surgery. Nevertheless, the addition of PRP hardly influenced bony regeneration, ceramic degradation or cytokine expression when bone substitutes were applied. At 12 weeks, the level of reossification had adjusted similarly in all groups. CONCLUSION:PRP did not add additional benefit when xenogenic bone substitutes were used. However, a significant effect on bone regeneration was found in the autogenous group initially when PRP is added.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Wiltfang J,Kloss FR,Kessler P,Nkenke E,Schultze-Mosgau S,Zimmermann R,Schlegel KAdoi
10.1111/j.1600-0501.2004.00980.xsubject
Has Abstractpub_date
2004-04-01 00:00:00pages
187-93issue
2eissn
0905-7161issn
1600-0501pii
980journal_volume
15pub_type
杂志文章abstract:INTRODUCTION:Maxillary sinus augmentation is a predictable implant site development technique, although several local and systemic factors may influence outcomes. The aim of this study was to evaluate healing patterns and bone remodeling activity following the use of two different graft mixtures for maxillary sinus aug...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0501.2010.02073.x
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:To evaluate how bone-level implants maintain crestal bone stability after thickening of thin mucosal tissues with allogenic membrane. MATERIALS AND METHODS:Ninety-seven bone-level implants of 4.1 mm diameter (Institute Straumann AG, Switzerland) were evaluated in 97 patients (28 men and 69 women, mean age 47...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12301
更新日期:2015-02-01 00:00:00
abstract::The aim of this in vitro study was to determine whether the sinus mucosa holds cells with an osteogenic potential. Frozen sections of sinus mucosa from three adult pigs were investigated for the expression of STRO-1, a marker of mesenchymal progenitor cells, and alkaline phosphatase activity, an enzyme expressed by ce...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.01062.x
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVES:To prospectively evaluate, as part of an ongoing randomized pilot trial, the clinical outcomes of two-piece zirconia implants in comparison with titanium implants 80 months after delivery of all-ceramic (lithium disilicate) single-tooth restorations. MATERIAL AND METHODS:The original sample included 31 (16 ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13576
更新日期:2020-04-01 00:00:00
abstract::Sinus augmentation has been advocated to be a surgical technique with predictable results in peri-implant surgery. Endoscopic surgery of the maxillary sinus so far has been used as diagnostic procedure. In this paper, the use of endoscopy is described as a low invasive adjunctive technique in sinus floor augmentation....
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1997.080612.x
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:The purpose of the present prospective follow-up study was to evaluate the long-term influence of the peri-implant keratinized mucosa (KM) on marginal bone level (MBL), peri-implant tissues health, and brushing discomfort. MATERIAL AND METHODS:Eighty patients were initially recruited during their maintenance...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13381
更新日期:2018-12-01 00:00:00
abstract::Ramírez-Fernández MP, Calvo-Guirado JL, Arcesio Delgado-Ruiz R, Maté-Sánchez del Val JE, Gómez-Moreno G, Guardia J. Experimental model of bone response to xenografts of bovine origin (Endobon® ): a radiological and histomorphometric study. Clin Oral Impl Res. 2011;22: 727-734. The above article, published online on 29...
journal_title:Clinical oral implants research
pub_type: 杂志文章,撤回出版物
doi:10.1111/clr.13085
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of vertical and periosteal-releasing incisions (PRI) on the extension of the buccal flap in a trapezoidal flap design. MATERIAL AND METHODS:Thirty patients scheduled for implant surgery accompanied by bone augmentation were recruited. The amount of flap extension pulled with a minimal...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02244.x
更新日期:2012-08-01 00:00:00
abstract::The present study describes the use of a degradable and a non-degradable material for guided bone regeneration. Forty rabbits were divided into 5 groups. Bicortical defects 15 mm in diameter were prepared in rabbit calvaria. A titanium microplate was placed over the defect to prevent collapse of the membrane. The calv...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1998.090504.x
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVES:To investigate the effect of treated periodontitis on implant outcomes in partially edentulous individuals compared with periodontally healthy patients. MATERIAL AND METHODS:Longitudinal studies reporting on implant survival, success, incidence of peri-implantitis, bone loss and periodontal status, and on p...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/clr.12684
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:Minor sinus floor elevation is a method with relatively high predictability but is technically demanding. Improvement of the technique and increase in the predictability are desirable. MATERIAL AND METHODS:A clinical protocol for minor sinus floor elevation with SLA-ITI (large grit acid-etched implants with...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01161.x
更新日期:2005-10-01 00:00:00
abstract::The aim of the present study was to evaluate the soft tissue response to intra-orally exposed and contaminated titanium surfaces (machined, blasted or polished) after being chemically and/or mechanically cleaned. Eight adult Sprague-Dawley rats were used for histomorphometrical and histological analyses. A total of 44...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2000.011004370.x
更新日期:2000-08-01 00:00:00
abstract:OBJECTIVES:To compare clinical and radiographic outcomes between transcrestal sinus floor elevation (TSFE) and lateral sinus floor elevation (LSFE) approaches of simultaneous implant placement in atrophic maxilla. MATERIALS AND METHODS:Patients with a residual bone height (RBH) ≤6 mm were enrolled and randomly assigne...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13688
更新日期:2020-11-21 00:00:00
abstract:OBJECTIVES:To investigate: (1) sinus membrane thickness in patients receiving lateral window sinus augmentation via cone-beam computed tomography (CBCT) and (2) the influence of Schneiderian membrane thickness upon membrane perforation during lateral window approach. MATERIAL AND METHODS:A total of 73 subjects with 81...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12646
更新日期:2016-05-01 00:00:00
abstract::We tested in a randomized controlled clinical trial the effect of pain and instability of dentures on bite force with different degrees of mucosal support. The trial involved 3 groups who had received: 1) a new conventional denture (CD-group), 2) an implant-mucosa-borne overdenture on 2 IMZ implants (IMZ-group) or 3) ...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-0501.2001.012001046.x
更新日期:2001-02-01 00:00:00
abstract::This review article provides an overview of cone beam (CB) imaging technology and its role in orofacial imaging, including comparison with two-dimensional (2D) radiography and multislice computed tomography (MCT). The radiation dose levels of CB systems are discussed, with reference to those delivered by MCT and commo...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2010.01996.x
更新日期:2010-11-01 00:00:00
abstract:INTRODUCTION:Despite the high success rates of endosseous oral implants, restrictions have been advocated to their placement with regard to the bone available in height and volume. The use of short or nonstandard-diameter implants could be one way to overcome this limitation. MATERIAL AND METHODS:In order to explore t...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2006.01349.x
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVES:Interforaminal implant surgery requires anatomical knowledge of the area and adequate information on the location of the various landmarks of significance such as the mental foramen, the anterior loop of the inferior alveolar nerve and the mandibular incisive canal. Cone beam computed tomography (CBCT) is a ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02261.x
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Different therapeutic concepts and methods have been proposed for improving dental implant outcomes in three specific clinical situations: (i) the fresh extraction socket with alveolar ridge preservation protocols; (ii) the posterior maxilla with limited bone height with either the placement of regular-sized...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12674
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVES:To assess retrospectively, over at least 5 years, the incidences of technical and biological complications and failures in young adult patients with birth defects affecting the formation of teeth. MATERIAL AND METHODS:All insurance cases with a birth defect that had crowns and fixed dental prostheses (FDPs)...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2009.01720.x
更新日期:2009-08-01 00:00:00
abstract:AIM:The objective of the study was to compare (i) esthetic, (ii) clinical and (iii) patient-centered outcomes following immediate (Type 1) and early implant placement (Type 2). MATERIAL AND METHODS:Thirty-eight subjects needing a single extraction (premolar to premolar) were randomly allocated to Type 1 or Type 2 impl...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12577
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:The aim of this systematic review was to investigate the influence of bone mineral density on the primary stability of dental implants. MATERIAL AND METHODS:A search of health science databases (Cochrane Library, MEDLINE-PubMed, ISI Web of Knowledge, EMBASE, LILACS) and grey literature was performed, includi...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2011.02228.x
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To analyze the outcomes of static computer-aided implant placement (sCAIP) compared to partially guided (PGIP) and free-handed (FHIP) implant placement. MATERIAL AND METHODS:This study was registered in PROSPERO (CRD42019131397). A comprehensive literature search was performed by two independent examiners. O...
journal_title:Clinical oral implants research
pub_type: 杂志文章,meta分析
doi:10.1111/clr.13635
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Minimizing crestal bone loss following immediate implant placement is considered the most challenging aspect in implant therapy. Implant surface topography and chemical modifications have been shown to influence the success of Osseointegration. The Straumann Bone Level implant, featuring SLActive surface, ha...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12388
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVES:In regenerative medicine, surface engineering of bioinert synthetic materials is often required in order to introduce bioactive species that can promote cell adhesion, proliferation, viability and enhanced ECM-secretion functions. The aim of this work is to study cell interaction with alumina-modified surfac...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01642.x
更新日期:2009-03-01 00:00:00
abstract::This study was undertaken to evaluate the use of tissue-engineered bone as grafting material for alveolar augmentation with simultaneous implant placement. Twelve adult hybrid dogs were used in this study. One month after the extraction of teeth in the mandible region, bone defects on both sides of the mandible were i...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2006.01246.x
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the influence of the configuration of the marginal aspect of implants placed immediately into extraction sockets on peri-implant hard tissue adaptation. MATERIAL AND METHODS:In 6 Labrador dogs, endodontic treatments of the mesial roots of 1 M1 were performed and the distal roots were removed. 2 P...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12262
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVES:The purpose of this in vitro study was to evaluate fracture loads of implant-supported zirconia-based prostheses fabricated with different veneer materials (resin-based material and lithium disilicate ceramics). MATERIAL AND METHODS:Forty-four zirconia-based molar prostheses were fabricated on dental implan...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13135
更新日期:2018-04-01 00:00:00
abstract::Four different surface modifications were designed. Forty screw-shaped implants were divided into 4 groups, 10 screws in each. Every screw was prepared with 2 different surface topographies. The surface topography was measured with a confocal laser scanning profilometer and the surface roughness was characterized usin...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1998.090102.x
更新日期:1998-02-01 00:00:00
abstract:AIMS/BACKGROUND:Empirically, for implant placement associated with sinus floor augmentation, a minimum of five mm of residual crestal bone height has been recommended in order to achieve sufficient initial implant stability. It has been the aim of the study to test this assumption in an experimental animal trial. MATE...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01570.x
更新日期:2009-08-01 00:00:00