Abstract:
:This study was undertaken to evaluate the use of tissue-engineered bone as grafting material for alveolar augmentation with simultaneous implant placement. Twelve adult hybrid dogs were used in this study. One month after the extraction of teeth in the mandible region, bone defects on both sides of the mandible were induced using a trephine bar with a diameter of 10 mm. Dog mesenchymal stem cells (dMSCs) were obtained via iliac bone biopsy and cultured for 4 weeks before implantation. After installing the dental implants, the defects were simultaneously implanted with the following graft materials: (i) fibrin, (ii) dMSCs and fibrin (dMSCs/fibrin), (iii) dMSCs, platelet-rich plasma (PRP) and fibrin (dMSCs/PRP/fibrin) and (iv) control (defect only). The implants were assessed by histological and histomorphometric analysis, 2, 4 and 8 weeks after implantation. The implants exhibited varying degrees of bone-implant contact (BIC). The BIC was 17%, 19% and 29% (control), 20%, 22% and 25% (fibrin), 22%, 32% and 42% (dMSCs/fibrin) and 25%, 49% and 53% (dMSCs/PRP/fibrin) after 2, 4 and 8 weeks, respectively. This study suggests that tissue-engineered bone may be of sufficient quality for predictable enhancement of bone regeneration around dental implants when used simultaneous by with implant placement.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Ito K,Yamada Y,Naiki T,Ueda Mdoi
10.1111/j.1600-0501.2006.01246.xsubject
Has Abstractpub_date
2006-10-01 00:00:00pages
579-86issue
5eissn
0905-7161issn
1600-0501pii
CLR1246journal_volume
17pub_type
杂志文章abstract:OBJECTIVES:The outcome of oral rehabilitation is usually monitored with clinical tests rather than by patient's perception of change. The aim of this study was to describe the objective measure and subjective perception of oral rehabilitation in patients with tooth agenesis. MATERIAL AND METHODS:The study included 129...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01698.x
更新日期:2009-07-01 00:00:00
abstract:AIM:To investigate bone-to-implant bonding for some novel surface modifications with a hierarchic structure and to correlate the in vivo results with surface roughness parameters. MATERIALS AND METHODS:Newly developed implants surfaces were tested in rabbits and compared with the commercially available OsseoSpeed™ (OS...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02233.x
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this prospective study was to evaluate one-stage dental implants clinically and radiographically after 10 years in function. MATERIAL AND METHODS:Twenty-five patients with a total of 68 implants [46 hollow screws (HS) and 22 hollow cylinders (HC)] who previously participated in 5-year prospect...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01479.x
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate a new design of the cervical portion of dental implant with the objective to increase the volume of peri-implant tissues in the crestal area. MATERIALS AND METHODS:Forty-eight tapered dental titanium implants with internal conical connection were implanted in healed alve...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12978
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:Protocols of immediate loading have been reported in several studies. It has also been demonstrated that the cause of failure of immediate loaded implants is due to the micromotion on the bone-implant interface induced by immediate loading. There should be a minimum gap between the implant and the peri-impla...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02036.x
更新日期:2011-05-01 00:00:00
abstract::Bone anchored implants are now being used in dentistry for supporting intraoral and craniofacial prostheses. Although high success rates have been reported, a small number of implants may fail during the early healing phase or lateral in function. Currently available clinical methods to determine implant stability and...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1996.070308.x
更新日期:1996-09-01 00:00:00
abstract::The principle of guided tissue regeneration was applied in an attempt to generate bone to cover a subperiosteal implant. Titanium frame works, casted on individual impressions of the anterior surface of the tibia of 4 Copenhagen White rabbits, were stabilized to the tibia by microscrews, and half of them were covered ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1995.060303.x
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVE:The aim of this systematic review was to investigate the influence of bone mineral density on the primary stability of dental implants. MATERIAL AND METHODS:A search of health science databases (Cochrane Library, MEDLINE-PubMed, ISI Web of Knowledge, EMBASE, LILACS) and grey literature was performed, includi...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2011.02228.x
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:The early effect of platelet-rich plasma (PRP) on bone regeneration in combination with dense biphasic hydroxyl apatite (HA)/beta-tricalcium phosphate (TCP) particles (ratio 60%/40%) was evaluated in rat cranial defects with a diameter of 6.2 mm. We hypothesize that PRP exerts its beneficial effect on bone re...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2006.01327.x
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the effect of scan mode of the cone beam computed tomography (CBCT) in the preoperative dental implant measurements. MATERIAL AND METHODS:Completely edentulous mandibles with entirely resorbed alveolar processes were selected for this study. Five regions were selected (i...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12080
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the demographic, radiological and therapeutic parameters that influence the overall clinical performance of palatal implants subjected to orthodontic loading. PATIENTS AND METHODS:The data of all patients who had received an orthodontic palatal implant for skeletal anchorage between January 1998 ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1600-0501.2011.02197.x
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:To evaluate how vertical mucosal tissue thickness affects crestal bone stability around triangular-shaped bone-level implants, restored with low profile titanium bases and monolithic lithium disilicate restorations. MATERIAL AND METHODS:Fifty-five bone-level implants of 4.3 mm diameter were evaluated in 55 p...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13263
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:To evaluate graft remodelling according to the distance from the native bone in maxillary sinuses grafted with anorganic bovine bone (ABB). MATERIAL AND METHODS:Bilateral sinus grafting was performed in twenty patients with residual bone height <5 mm before implant placement. After 8 months, biopsy samples ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13639
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:Data on posterior alveolar ridge resorption (PARR) in patients with two implant supported mandibular overdentures is very heterogeneous. The aim of this prospective study was to observe the PARR after ten years for a study population treated with a titanium bar retained overdenture on two IMZ-implants. MATE...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1111/clr.12393
更新日期:2015-12-01 00:00:00
abstract::In 8 monkeys both the maxillary lateral incisors were extracted. In the 16 extraction sites an Al2O3-ceramic dental implant (Frialit) was immediately inserted. Eight implants were submerged under the oral mucosa and the other 8 were allowed to penetrate through the mucosa during the observation period. None of the imp...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1995.060206.x
更新日期:1995-06-01 00:00:00
abstract:BACKGROUND:During the fourth Summer Camp (SC) held by the European Association of Osseointegration (EAO), 20 junior representatives from various European and non-European universities and associations were selected to partake in oral presentation and communication skill development. AIMS:The aim of the EAO Summer Camp...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13625
更新日期:2020-08-01 00:00:00
abstract::The information concerning the molecular events taking place in onlay bone grafts are still incipient. The objective of the present study is to correlate the effects of perforation of resident bone bed on (1) the timing of onlay autogenous graft revascularization; (2) the maintenance of volume/density of the graft (as...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01485.x
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:The role of nanoscale/submicron morphological features in the process of osseointegration is largely unknown. This study reports the creation of a unique submicrofeatured titanium surface by a combination of anodic oxidation and sandblasting and determines how the addition of this submicrofeature to a microro...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02507.x
更新日期:2013-09-01 00:00:00
abstract:AIM OF THE STUDY:To evaluate the survival and success rate of Straumann Bone Level implants placed in vertically atrophied edentulous jaws previously reconstructed with autogenous onlay bone grafts taken from the calvarium or the mandibular ramus. MATERIALS AND METHODS:From 2007 to 2009, 18 patients presenting with ve...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02262.x
更新日期:2012-09-01 00:00:00
abstract:AIM:The aim of this prospective, randomized, controlled multicenter study was to determine the 3-year efficacy and stability of the soft and hard tissues at implants with a different geometry that were placed in fresh extraction sockets. MATERIAL AND METHODS:Implants with two different configurations, cylindrical (Gro...
journal_title:Clinical oral implants research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/clr.12140
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:Despite the high success rates of endosseous oral implants, restrictions have been advocated to their placement with regard to the bone available in height and volume. The use of short or nonstandard-diameter implants could be one way to overcome this limitation. MATERIAL AND METHODS:In order to explore t...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2006.01349.x
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:Recent studies have suggested that magnesium (Mg) ions exert a beneficial effect on implant osseointegration. This study assessed the osseointegration of nanoporous titanium (Ti) surface incorporating the Mg produced by hydrothermal treatment in rabbit cancellous bone to determine whether this surface would f...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02144.x
更新日期:2012-03-01 00:00:00
abstract::The aim of this study was to compare implant-bone interface stresses and peri-implant principal strains in anisotropic versus isotropic three-dimensional finite element models of an osseointegrated implant in the posterior mandible. We obtained anisotropic (transversely isotropic) elastic constants for mandibular bone...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2001.120614.x
更新日期:2001-12-01 00:00:00
abstract:AIM:The aim of this biomechanical study was to assess the influence of self-tapping blades in terms of primary implant stability between implants with self-tapping blades and implants without self-tapping blades using five different analytic methods, especially in medium-density bone. MATERIALS AND METHODS:Two differe...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02089.x
更新日期:2011-10-01 00:00:00
abstract:INTRODUCTION:Dental implants have traditionally been made from titanium or its alloys, but recently full-ceramic implants have been developed with comparable osseointegration properties and functional strength properties to titanium. These ceramic implants may have advantages in certain patients and situations, for exa...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12598
更新日期:2016-12-01 00:00:00
abstract::Treatment with denture for edentulous people is highly important for maintaining quality of life. However, its effect on the brain is unknown. In this experimental study, we hypothesized that dental prosthesis can recover not only the physical condition of mastication system but also the regional brain activity. We ev...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01171.x
更新日期:2005-12-01 00:00:00
abstract:OBJECTIVE:The influence of progressively high concentrations of platelet-rich plasma (PRP) on human osteoblast hFOB1.19 proliferation was evaluated. MATERIAL AND METHODS:The PRP was obtained from a human source. Two experiments were conducted. In the first one, PRP was diluted to 50%, 25%, 12.5% and 6.125% (v/v) with ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01145.x
更新日期:2005-08-01 00:00:00
abstract:INTRODUCTION:The objectives of this working group were to update the existing knowledge base in computer-guided implant treatment (accuracy and clinical advantages), to search for scientific evidence on the need for keratinized tissue around implants, and to review recent literature in the search for new insights into ...
journal_title:Clinical oral implants research
pub_type: 共识发展会议,杂志文章,评审
doi:10.1111/j.1600-0501.2012.02553.x
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:This study evaluated the influence of oestrogen deficiency and its therapies on bone tissue around osseointegrated implants. METHODS:Implants were placed in 66 female rats tibiae. The animals were assigned into five groups: control (CTL), sham, ovariectomy (OVX), oestrogen (EST), and alendronate (ALE). Whil...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.01989.x
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:Using computed tomography, to compare vertical and volumetric bone augmentation after interposition grafting with bovine bone mineral matrix (GEISTLICH BIO-OSS® ) or hydroxyapatite/tricalcium phosphate (STRAUMANN® BONECERAMIC) for atrophic posterior mandible reconstruction through segmental osteotomy. MATERI...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12985
更新日期:2017-10-01 00:00:00