Abstract:
OBJECTIVE:The role of nanoscale/submicron morphological features in the process of osseointegration is largely unknown. This study reports the creation of a unique submicrofeatured titanium surface by a combination of anodic oxidation and sandblasting and determines how the addition of this submicrofeature to a microroughened surface affects the early-stage process of osseointegration. MATERIALS AND METHODS:Nonmicroroughened implants were prepared by machining Ti-6Al-4V alloy in a cylindrical form (1 mm diameter and 2 mm long). Microroughened implants were prepared by sandblasting machined implants, while submicrofeatured implants were created by anodic oxidation of the sandblasted implants. Implants were placed into rat femurs and subjected to biomechanical, interfacial, and histological analyses at 1 and 2 weeks post-implantation (n = 6). RESULTS:The submicrotopography was characterized by 50-300 nm nodules and pits in addition to other submicron-level irregularities formed entirely within the sandblast-created microstructures. The biomechanical strength of osseointegration increased continuously from week 1 to 2 for the submicrofeatured implants but not for the microroughened implants. A significant increase in bone-implant contact and bone volume, as well as a reduction in soft tissue intervention, were commonly found for the microroughened surface and the submicrofeatured surface compared with the nonmicroroughened surface. However, there were no differences in these parameters between the microroughened surface and the submicrofeatured surface. An extensive area of bone tissue at the submicrofeatured implant interface was retained intact after biomechanical shear testing, while the microroughened implant-tissue interface showed a gap along the entire axis of the implant, leading to clear separation of the tissue during the shear procedure. CONCLUSIONS:This study demonstrates that a submicrofeatured titanium surface created by a combination of sandblasting and anodic oxidation enhances the strength of early-stage osseointegration, primarily because of the increased resistance of peri-implant bone tissue against external force rather than modulation of bone morphogenesis.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Yamada M,Ueno T,Minamikawa H,Ikeda T,Nakagawa K,Ogawa Tdoi
10.1111/j.1600-0501.2012.02507.xsubject
Has Abstractpub_date
2013-09-01 00:00:00pages
991-1001issue
9eissn
0905-7161issn
1600-0501journal_volume
24pub_type
杂志文章abstract::The aim of the present study was (i) to investigate the relation between specific interleukin-1 (IL-1) gene polymorphisms and peri-implant bone loss at osseointegrated ITI(R) dental implants and (ii) to explore the association between these allelic variants of the IL-1 gene complex and peri-implant mucosal inflammatio...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2003.140102.x
更新日期:2003-02-01 00:00:00
abstract::The aim of the present study was to evaluate the effect of augmenting the maxillary alveolar ridge and the lateral aspect of the mandible with onlay autogeneic cortico-cancellous bone grafts that were covered with e-PTFE membranes. The experiment was carried out in 51 rats. In 15 rats, the edentulous maxillary jaw bet...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130210.x
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVES:To compare the effect of two surgical techniques, lateral condensation and bone drilling, on changes in temperature of the adjacent low-density bone during implant placement into posterior maxilla and to investigate the influence of the host factors - age, gender, region of implantation, bone density, and th...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12191
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate the preference of a patients' population, according to the index of willingness to pay (WTP), against two treatments to restore a single-tooth gap: the implant-supported crown (ISC) and the 3-unit fixed partial denture prosthesis (FPDP) on natural teeth. MATERIALS ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12264
更新日期:2014-11-01 00:00:00
abstract::The aim of the present study was to evaluate if early access to the endosteal bone compartment by removal of the outer cortical bone plate will enhance bone augmentation in a secluded space. Two titanium cylinders were placed on the skull of each of 8 rabbits. Each cylinder was placed into a circular slit, secured to ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVE:To evaluate osseointegration in rabbit tibiae and to investigate surface characteristics of novel zirconia implants made by powder injection molding (PIM) technique, using molds with and without roughened inner surfaces. MATERIAL AND METHODS:A total of 20 rabbits received three types of external hex implants...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02468.x
更新日期:2013-05-01 00:00:00
abstract::This paper reports a 5-year life-table analysis on wide neck (WN) ITI implants placed in a private practice. In 212 patients, 263 implants were placed in the posterior region; 97% rehabilitated the molar area. Implants in the mandible and in the maxilla were 61.2% and 38.8%, respectively; the mean implant length was 9...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2006.01271.x
更新日期:2006-10-01 00:00:00
abstract::Treatment with denture for edentulous people is highly important for maintaining quality of life. However, its effect on the brain is unknown. In this experimental study, we hypothesized that dental prosthesis can recover not only the physical condition of mastication system but also the regional brain activity. We ev...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01171.x
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:The aim of this study was to compare between the effects of resilient liner and clip attachments of bar-implant-retained mandibular overdenture on peri-implant tissues. MATERIALS AND METHODS:In a randomized-controlled clinical trial, 30 edentulous male patients (mean age 62.5 years) were equally assigned to tw...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0501.2009.01879.x
更新日期:2010-05-01 00:00:00
abstract::The information concerning the molecular events taking place in onlay bone grafts are still incipient. The objective of the present study is to correlate the effects of perforation of resident bone bed on (1) the timing of onlay autogenous graft revascularization; (2) the maintenance of volume/density of the graft (as...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01485.x
更新日期:2008-04-01 00:00:00
abstract::The purpose of this study was to compare the clinical and microbiological (microscopic) parameters during the development of experimental gingivitis and experimental peri-implant mucositis. Twenty partially edentulous patients were treated for moderate to advanced periodontal disease. Following active periodontal ther...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1994.050409.x
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVES:To measure in vivo impact of dense bone overheating on implant osseointegration and peri-implant bone resorption comparing different bur irrigation methods vs. no irrigation. MATERIALS AND METHODS:Twenty TI-bone implants were inserted in the inferior edge of mandibles of sheep. Different cooling procedures ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12127
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVES:To compare clinical and radiographic outcomes between transcrestal sinus floor elevation (TSFE) and lateral sinus floor elevation (LSFE) approaches of simultaneous implant placement in atrophic maxilla. MATERIALS AND METHODS:Patients with a residual bone height (RBH) ≤6 mm were enrolled and randomly assigne...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13688
更新日期:2020-11-21 00:00:00
abstract:AIMS/BACKGROUND:Empirically, for implant placement associated with sinus floor augmentation, a minimum of five mm of residual crestal bone height has been recommended in order to achieve sufficient initial implant stability. It has been the aim of the study to test this assumption in an experimental animal trial. MATE...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01570.x
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVES:To study the peri-implant bone organization pattern of immediately loaded (IL) zirconia implants with microgrooved surfaces. MATERIALS AND METHODS:Forty-eight dental implants of 4 mm diameter and 10 mm length were inserted after two months postextraction healing in the edentulous mandible of six dogs. Three...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12461
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:After implant insertion and loading, crestal bone usually undergoes remodeling and resorption. If the horizontal relationship between the outer edge of the implant and a smaller-diameter component ('platform switching') is altered, there seems to be reduced crestal bone loss. Immediate loading allows immedia...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01449.x
更新日期:2008-03-01 00:00:00
abstract::This paper reports on a 7-year life table analysis on ITI titanium plasma-sprayed (TPS) and sandblasted and etched (SLA) implants placed in a private practice and loaded for at least 1 year. In 236 patients, 528 (264 TPS and 264 SLA) implants were placed, 351 (66.5%) implants rehabilitated the posterior region and 71....
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.00978.x
更新日期:2004-04-01 00:00:00
abstract::The aim of this in vitro study was to determine whether the sinus mucosa holds cells with an osteogenic potential. Frozen sections of sinus mucosa from three adult pigs were investigated for the expression of STRO-1, a marker of mesenchymal progenitor cells, and alkaline phosphatase activity, an enzyme expressed by ce...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.01062.x
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVES:Maintaining oral health around titanium implants is essential. The formation of a biofilm on the titanium surface will influence the continuing success of the implant. These concerns have led to modified ultrasonic scaler instruments that look to reduce implant damage while maximising the cleaning effect. Th...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02186.x
更新日期:2012-01-01 00:00:00
abstract:AIMS:To determine whether endoscope-guided sinus elevation procedures can be consistently used to create sufficient bone support for stable implant placement and long-term implant success. MATERIAL AND METHODS:Sixty-two implants were surgically placed into 30 patients (14 men and 16 women) following internal sinus ele...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01561.x
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate a new design of the cervical portion of dental implant with the objective to increase the volume of peri-implant tissues in the crestal area. MATERIALS AND METHODS:Forty-eight tapered dental titanium implants with internal conical connection were implanted in healed alve...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12978
更新日期:2018-07-01 00:00:00
abstract::The aim of the study was to evaluate the early colonization of non-submerged implants over a 6-month period in partially edentulous patients treated for advanced aggressive periodontal disease. In 22 patients treated for advanced aggressive periodontitis and in a supportive maintenance program for a period between 12 ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01175.x
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVES:To evaluate the potential influence of different cone-beam computed tomography (CBCT) devices on the transfer accuracy of an open-source system for computer-aided implantology (CAI). MATERIAL AND METHODS:A total of 108 implants in 18 partially edentulous patient-equivalent models were planned and fully guid...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02272.x
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the bone regenerative properties of a heat treated cross-linked GBR membrane with zinc hydroxyapatite powders in the rat calvarial defect model over a 6-week period. MATERIAL AND METHODS:In vitro physio-chemical characterization involved X-ray diffraction analysis, s...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12520
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To use cone beam computed tomography (CBCT) to assess the alterations of socket dimensions after a 6-month healing period following molar extraction. MATERIALS AND METHODS:Seventeen molars were extracted due to advanced periodontitis. CBCT scans were taken immediately after extraction and once more 6 months ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13418
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVES:To assess the impact of collagen membrane application on bone formation surrounding implants placed simultaneously with the bone ring technique. MATERIAL AND METHODS:Dental implants were inserted simultaneously with the bone ring technique in standardized, vertical alveolar bony defects in the mandible of d...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13543
更新日期:2020-01-01 00:00:00
abstract::The aim of the study was to investigate temperature changes at the implant-bone interface during simulated implant surface decontamination with a 809-nm gallium-aluminium-arsenid (GaAlAs) semiconductor laser. Stepped cylinder implants with a diameter of 3.8 mm and a length of 11 mm with two different surfaces (sand-bl...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2003.140112.x
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:This short communication reports on a novel digital technique designated - the "Fully Digital Technique (FDT)" - to take the impression of the peri-implant soft tissue and emergence profile with an intraoral scanner, digitally capturing both the three dimensional position of the implant platform and the coron...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12599
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:To investigate the role of different levels of pH of artificial saliva under simulated oral environment on the corrosion behavior of commercially pure titanium (cp-Ti) and Ti-6Al-4V alloy. Special attention is given to understand the changes in corrosion kinetics and surface characterization of Ti by using e...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02265.x
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:To assess, based on the existing literature, the benefit of socket preservation therapies in patients with a tooth extraction in the anterior or premolar region as compared with no additional treatment with respect to bone level. MATERIAL AND METHODS:MEDLINE-PubMed and the Cochrane Central Register of contro...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2010.02064.x
更新日期:2011-08-01 00:00:00