Immunohistochemical, tomographic and histological study on onlay iliac grafts remodeling.

Abstract:

:The information concerning the molecular events taking place in onlay bone grafts are still incipient. The objective of the present study is to correlate the effects of perforation of resident bone bed on (1) the timing of onlay autogenous graft revascularization; (2) the maintenance of volume/density of the graft (assessed through tomography); and (3) the occurrence of bone remodeling proteins (using immunohistochemistry technique) delivered in the graft. Thirty-six New Zealand White rabbits were subjected to iliac crest onlay bone grafting on both sides of the mandible. The bone bed was drill-perforated on one side aiming at accelerating revascularization, whereas on the other side it was kept intact. After grafts fixation and flaps suture all animals were submitted to tomography on both mandible sites. Six animals were sacrificed, respectively, at 3, 5, 7, 10, 20 and 60 days after surgery. A second tomography was taken just before sacrifice. Histological slides were prepared from each grafted site for both immunohistochemistry analysis [osteopontin, osteocalcin, type I collagen and vascular endothelial growth factor (VEGF) anti-bodies] and histometric analysis. The values on bone volume measured on tomography showed no statistic significance (P>or=0.05) between perforated and intact sites. Grafts placed on perforated beds showed higher bone density values compared with non-perforated ones at 3 days (P

journal_name

Clin Oral Implants Res

authors

Faria PE,Okamoto R,Bonilha-Neto RM,Xavier SP,Santos AC,Salata LA

doi

10.1111/j.1600-0501.2007.01485.x

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

393-401

issue

4

eissn

0905-7161

issn

1600-0501

pii

CLR1485

journal_volume

19

pub_type

杂志文章
  • Sequential healing of onlay bone grafts using combining biomaterials with cross-linked collagen in dogs.

    abstract:OBJECTIVES:The aim of this study was to observe the sequential healing of onlay grafts in terms of the volumetric and histologic changes using different bone substances and absorbable membranes according to the presence of collagen cross-linking. MATERIAL AND METHODS:Four groups involving onlay grafting with different...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12763

    authors: Cha JK,Joo MJ,Yoon S,Lee JS,Choi SH,Jung UW

    更新日期:2017-01-01 00:00:00

  • Clinical outcomes of magnesium-incorporated oxidised implants: a randomised double-blind clinical trial.

    abstract:OBJECTIVES:This study evaluated implant stability and clinical outcomes obtained with magnesium-incorporated oxidised implants (Mg titanate) and compared them to those blasted magnesium-incorporated oxidised implants (blasted Mg titanate). PATIENTS AND METHODS:Mg titanate was manufactured using the microarc oxidation ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.12091

    authors: Pang KM,Lee JW,Lee JY,Lee JB,Kim SM,Kim MJ,Lee JH

    更新日期:2014-05-01 00:00:00

  • Morbidity of harvesting of chin grafts: a prospective study.

    abstract::In a prospective study, 20 patients who underwent harvesting of chin grafts as outpatients, were followed up for 12 months (3 further patients with incomplete follow-up data were excluded from the study). Preoperatively and 7 days, 1, 3, 6 and 12 months postoperatively, follow-up data were assessed. Evaluation of the ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.2001.120510.x

    authors: Nkenke E,Schultze-Mosgau S,Radespiel-Tröger M,Kloss F,Neukam FW

    更新日期:2001-10-01 00:00:00

  • A prospective, randomized pilot study on the safety and efficacy of recombinant human growth and differentiation factor-5 coated onto β-tricalcium phosphate for sinus lift augmentation.

    abstract:OBJECTIVES:The aim of this prospective, randomized clinical trial was to investigate the potential of recombinant human growth and differentiation factor-5 (rhGDF-5) coated onto β-tricalcium phosphate (β-TCP) (rhGDF-5/β-TCP) to support bone formation after sinus lift augmentation. MATERIAL AND METHODS:In total, 31 pat...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/j.1600-0501.2010.01949.x

    authors: Koch FP,Becker J,Terheyden H,Capsius B,Wagner W

    更新日期:2010-11-01 00:00:00

  • The current use of patient-centered/reported outcomes in implant dentistry: a systematic review.

    abstract:AIM:To provide an update on the use of Patient-Reported Outcome Measures (PROMs) in the field of implant dentistry (1); to compare PROMs for prostheses supported by one or more implants to alternative treatment options or a healthy dentition (2). MATERIALS AND METHODS:The dental literature was searched on PubMed until...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,评审

    doi:10.1111/clr.12634

    authors: De Bruyn H,Raes S,Matthys C,Cosyn J

    更新日期:2015-09-01 00:00:00

  • Soft tissue response to clinically contaminated and thereafter cleaned titanium surfaces. An experimental study in the rat.

    abstract::The aim of the present study was to evaluate the soft tissue response to intra-orally exposed and contaminated titanium surfaces (machined, blasted or polished) after being chemically and/or mechanically cleaned. Eight adult Sprague-Dawley rats were used for histomorphometrical and histological analyses. A total of 44...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.2000.011004370.x

    authors: Ericsson I,Lekholm U,Sennerby L,Holmén A

    更新日期:2000-08-01 00:00:00

  • Implant treatment in immunosuppressed renal transplant patients: A prospective case-controlled study.

    abstract:OBJECTIVES:The aim of this clinical study was to evaluate long-term outcomes of implant therapy in a cohort of immunosuppressed renal transplant patients compared with a matched control group. MATERIAL AND METHODS:Pharmacologically immunosuppressed renal transplant patients received dental implant treatment between 20...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.13437

    authors: Hernández G,Paredes V,López-Pintor RM,de Andrés A,de Vicente JC,Sanz M

    更新日期:2019-06-01 00:00:00

  • Pain and instability during biting with mandibular implant-retained overdentures.

    abstract::We tested in a randomized controlled clinical trial the effect of pain and instability of dentures on bite force with different degrees of mucosal support. The trial involved 3 groups who had received: 1) a new conventional denture (CD-group), 2) an implant-mucosa-borne overdenture on 2 IMZ implants (IMZ-group) or 3) ...

    journal_title:Clinical oral implants research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1600-0501.2001.012001046.x

    authors: Fontijn-Tekamp FA,Slagter AP,van 't Hof MA,Kalk W,Jansen JA

    更新日期:2001-02-01 00:00:00

  • Clinical efficacy of a xenogeneic collagen matrix in augmenting keratinized mucosa around implants: a randomized controlled prospective clinical trial.

    abstract:AIM:The aim of this controlled randomized clinical trial was to evaluate the efficacy of a xenogeneic collagen matrix (CM) to augment the keratinized tissue around implants supporting prosthetic restorations at 6 months when compared with the standard treatment, the connective tissue autograft, CTG). MATERIALS AND MET...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0501.2011.02260.x

    authors: Lorenzo R,García V,Orsini M,Martin C,Sanz M

    更新日期:2012-03-01 00:00:00

  • Randomized clinical trials in implant therapy: relationships among methodological, statistical, clinical, paratextual features and number of citations.

    abstract:OBJECTIVES:The aim of the present study was to investigate the relationships among reported methodological, statistical, clinical and paratextual variables of randomized clinical trials (RCTs) in implant therapy, and their influence on subsequent research. MATERIALS AND METHODS:The material consisted of the RCTs in im...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2007.01350.x

    authors: Nieri M,Clauser C,Franceschi D,Pagliaro U,Saletta D,Pini-Prato G

    更新日期:2007-08-01 00:00:00

  • Does residual cement around implant-supported restorations cause peri-implant disease? A retrospective case analysis.

    abstract:OBJECTIVES:The purpose of this study was to determine the relationship between patients with a history of periodontitis and development of cement-related peri-implant disease. MATERIALS AND METHODS:Seventy-seven patients with 129 implants for this retrospective analysis were selected from completed implant cases that ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2012.02570.x

    authors: Linkevicius T,Puisys A,Vindasiute E,Linkeviciene L,Apse P

    更新日期:2013-11-01 00:00:00

  • Early loading of single crowns supported by 6-mm-long implants with a moderately rough surface: a prospective 2-year follow-up cohort study.

    abstract:AIM:To evaluate prospectively the clinical and radiographic outcomes after 2 years of loading of 6 mm long moderately rough implants supporting single crowns in the posterior regions. MATERIAL AND METHODS:Forty SLActive Straumann short (6 mm) implants were placed in 35 consecutively treated patients. Nineteen implants...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2010.01942.x

    authors: Rossi F,Ricci E,Marchetti C,Lang NP,Botticelli D

    更新日期:2010-09-01 00:00:00

  • Alveolar bone resorption after primary tooth loss has a negative impact on straightforward implant installation in patients with agenesis of the lower second premolar.

    abstract:OBJECTIVES:To compare the alveolar bone dimensions in patients with lower second premolar (P2) agenesis prior to and after primary molar loss on CT scans, and assess the possibility for straightforward implant placement. METHODS:Alveolar bone dimensions were evaluated on 150 mandibular CT scans in three groups: (i) ag...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.13033

    authors: Bertl K,Bertl MH,Heimel P,Burt M,Gahleitner A,Stavropoulos A,Ulm C

    更新日期:2018-02-01 00:00:00

  • Influence of barrier occlusiveness on guided bone augmentation. An experimental study in the rat.

    abstract::The present study was designed to test perforated and non-perforated barriers for their ability to promote augmentation of bone tissue. More specifically, 1 totally occlusive barrier and 6 barriers with perforation sizes of about 10, 25, 50, 75, 100, and 300 microns and 1 group with no barriers placed (open test chamb...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.1998.090406.x

    authors: Lundgren A,Lundgren D,Taylor A

    更新日期:1998-08-01 00:00:00

  • Clinical denture base deformation with different attachments used to stabilize implant overdentures: A crossover study.

    abstract:OBJECTIVES:The aim of this crossover study was to compare clinical denture base deformation with different attachments used for mandibular implant overdentures. MATERIALS AND METHODS:Twenty-four patients with edentulous mandibular ridges received two implants in the former canine regions. Three months thereafter, each...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.13552

    authors: ELsyad MA,Fathe Mahanna F,Samir Khirallah A,Ali Habib A

    更新日期:2020-02-01 00:00:00

  • Transcriptional profiling of "guided bone regeneration" in a critical-size calvarial defect.

    abstract:OBJECTIVES:Guided bone regeneration (GBR) is a commonly utilized surgical technique in the craniofacial region. The transcriptional mechanisms associated with this type of bone regeneration are not well understood. The aim of this study was to characterize the transcriptome associated with GBR of a critical-size calvar...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2010.02104.x

    authors: Ivanovski S,Hamlet S,Retzepi M,Wall I,Donos N

    更新日期:2011-04-01 00:00:00

  • Esthetic, clinical and patient-centered outcomes of immediately placed implants (Type 1) and early placed implants (Type 2): preliminary 3-month results of an ongoing randomized controlled clinical trial.

    abstract:AIM:The objective of the study was to compare (i) esthetic, (ii) clinical and (iii) patient-centered outcomes following immediate (Type 1) and early implant placement (Type 2). MATERIAL AND METHODS:Thirty-eight subjects needing a single extraction (premolar to premolar) were randomly allocated to Type 1 or Type 2 impl...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.12577

    authors: Huynh-Ba G,Meister DJ,Hoders AB,Mealey BL,Mills MP,Oates TW,Cochran DL,Prihoda TJ,McMahan CA

    更新日期:2016-02-01 00:00:00

  • The effect of SLActive surface in guided bone formation in osteoporotic-like conditions.

    abstract:OBJECTIVES:The aim of the study was to evaluate new bone formation under etched titanium (SLA) and modified-etched hydrophilic titanium (modSLA) domes placed on the calvarium of healthy, osteoporotic and osteoporotic treated with bisphosphonates rabbits. METHODS:Experimental osteoporosis was induced by ovariectomy (OV...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2010.02094.x

    authors: Mardas N,Schwarz F,Petrie A,Hakimi AR,Donos N

    更新日期:2011-04-01 00:00:00

  • Sinus augmentation via transcrestal approach: a comparison between the balloon and osteotome technique in a cadaver study.

    abstract:BACKGROUND:The transcrestal approach with osteotomes is a commonly applied and predictable technique for maxillary sinus floor elevation. However, Schneiderian membrane perforation is a common and often inevitable intraoperative complication. Recently, the use of balloons has been proposed to reduce the risk of sinus m...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0501.2012.02506.x

    authors: Chan HL,Oh TJ,Fu JH,Benavides E,Avila-Ortiz G,Wang HL

    更新日期:2013-09-01 00:00:00

  • Impact of human maxillary sinus volume on grafts dimensional changes used in maxillary sinus augmentation: a multislice tomographic study.

    abstract:PURPOSE:To assess the influence of complete maxillary sinus volume on the dimensional changes of different grafts used in maxillary sinus lift. MATERIALS AND METHODS:Analysis of 50 surgical procedures of maxillary sinus lift performed on 43 subjects using different grafting materials: fresh frozen allogenic particulat...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12488

    authors: Favato MN,Vidigal BC,Cosso MG,Manzi FR,Shibli JA,Zenóbio EG

    更新日期:2015-12-01 00:00:00

  • Implant-supported fixed cantilever prostheses in partially edentulous arches. A seven-year prospective study.

    abstract::The purpose of the following study was to evaluate the medium- to long-term prognosis of implant-supported cantilever fixed prostheses, and to establish to what degree this is influenced by factors such as length, type of cantilever (mesial or distal), and opposite dentition versus cantilever prostheses. This study wa...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.2003.120905.x

    authors: Romeo E,Lops D,Margutti E,Ghisolfi M,Chiapasco M,Vogel G

    更新日期:2003-06-01 00:00:00

  • Professional and patient-based evaluation of oral rehabilitation in patients with tooth agenesis.

    abstract:OBJECTIVES:The outcome of oral rehabilitation is usually monitored with clinical tests rather than by patient's perception of change. The aim of this study was to describe the objective measure and subjective perception of oral rehabilitation in patients with tooth agenesis. MATERIAL AND METHODS:The study included 129...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2008.01698.x

    authors: Dueled E,Gotfredsen K,Trab Damsgaard M,Hede B

    更新日期:2009-07-01 00:00:00

  • Influence of the keratinized mucosa on the stability of peri-implant tissues and brushing discomfort: A 4-year follow-up study.

    abstract:OBJECTIVE:The purpose of the present prospective follow-up study was to evaluate the long-term influence of the peri-implant keratinized mucosa (KM) on marginal bone level (MBL), peri-implant tissues health, and brushing discomfort. MATERIAL AND METHODS:Eighty patients were initially recruited during their maintenance...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.13381

    authors: Perussolo J,Souza AB,Matarazzo F,Oliveira RP,Araújo MG

    更新日期:2018-12-01 00:00:00

  • A 5- to 6-year radiological evaluation of titanium plasma sprayed/sandblasted and acid-etched implants: results from private practice.

    abstract:OBJECTIVES:This study aimed to determine bone level changes after 5-6 years of follow-up for a large group of one-stage dental implants consecutively placed in private practice. Potential confounding factors influencing crestal bone loss (CBL) were also assessed. MATERIALS AND METHODS:A total of 378 transmucosal Strau...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12083

    authors: Dam HG,Najm SA,Nurdin N,Bischof M,Finkelman M,Nedir R

    更新日期:2014-02-01 00:00:00

  • Computer-guided implant therapy and soft- and hard-tissue aspects. The Third EAO Consensus Conference 2012.

    abstract:INTRODUCTION:The objectives of this working group were to update the existing knowledge base in computer-guided implant treatment (accuracy and clinical advantages), to search for scientific evidence on the need for keratinized tissue around implants, and to review recent literature in the search for new insights into ...

    journal_title:Clinical oral implants research

    pub_type: 共识发展会议,杂志文章,评审

    doi:10.1111/j.1600-0501.2012.02553.x

    authors: Sicilia A,Botticelli D,Working Group 3.

    更新日期:2012-10-01 00:00:00

  • In vitro cleaning potential of three implant debridement methods. Simulation of the non-surgical approach.

    abstract:OBJECTIVES:To assess the cleaning potential of commonly used implant debridement methods, simulating non-surgical peri-implantitis therapy in vitro. MATERIALS AND METHODS:One-hundred-and-eighty dental implants were ink-stained and mounted in combined soft and hard tissue models, representing peri-implantitis defects w...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12773

    authors: Ronay V,Merlini A,Attin T,Schmidlin PR,Sahrmann P

    更新日期:2017-02-01 00:00:00

  • The influence of abutment macro-design on clinical and radiographic peri-implant tissue changes for guided, placed, and restored implants: A 1-year randomized controlled trial.

    abstract:OBJECTIVES:The aim was to evaluate the peri-implant tissue levels over a 1-year period for implants connected to either convex or concave final abutments at the time of implant placement. MATERIALS AND METHODS:In this randomized, double masked, controlled clinical study, twenty-eight patients with one missing maxillar...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.13493

    authors: Koutouzis T,Adeinat B,Ali A

    更新日期:2019-09-01 00:00:00

  • Attitudes of general dental practitioners towards implant dentistry in an environment with widespread provision of implant therapy.

    abstract:OBJECTIVES:To determine attitudes of general dental practitioners in a community where provision dental implants is a well-known treatment modality; and to identify variations in the attitudes with respect to dentists' factors, training factors and implant provision factors. METHODS:A questionnaire survey to a random ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2012.02537.x

    authors: Lang-Hua BH,Lang NP,Lo EC,McGrath CP

    更新日期:2013-03-01 00:00:00

  • Cumulative costs for the prosthetic reconstructions and maintenance in young adult patients with birth defects affecting the formation of teeth.

    abstract:OBJECTIVES:To assess retrospectively the cumulative costs for the long-term oral rehabilitation of patients with birth defects affecting the development of teeth. METHODS:Patients with birth defects who had received fixed reconstructions on teeth and/or implants > or =5 years ago were asked to participate in a compreh...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2009.01711.x

    authors: Incici E,Matuliene G,Hüsler J,Salvi GE,Pjetursson B,Brägger U

    更新日期:2009-07-01 00:00:00

  • A randomized and controlled clinical trial of two different compositions of deproteinized bovine bone and autogenous bone used for lateral ridge augmentation.

    abstract:OBJECTIVE:The aim of the study was to radiologically and histologically evaluate the graft healing and volumetric changes after lateral augmentation with two different compositions of deproteinized bovine bone (DPBB) and autogenous bone (AB). MATERIAL AND METHODS:Thirteen patients with a mean age of 59.6 ± 12.1 years ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.12143

    authors: Mordenfeld A,Johansson CB,Albrektsson T,Hallman M

    更新日期:2014-03-01 00:00:00