Abstract：
OBJECTIVE:The influence of progressively high concentrations of platelet-rich plasma (PRP) on human osteoblast hFOB1.19 proliferation was evaluated. MATERIAL AND METHODS:The PRP was obtained from a human source. Two experiments were conducted. In the first one, PRP was diluted to 50%, 25%, 12.5% and 6.125% (v/v) with culture medium (Modified Eagle's Medium (MEM) : Ham's F12 Medium (HAM-F12%) and 1% antibiotics-antimicotic) supplemented with 10% of fetal bovine serum (FBS). In the second experiment, all conditions were identical except for the absence of FBS in the culture medium. RESULTS:The results of the osteoblast proliferation test were higher when stimulated by the 50% PRP dilution, with or without FBS. A further study is suggested to determine if concentrations above 50% could cause higher rates of osteoblast proliferation. In this study, the results were not statistically different (P<0.05) with 12.5% and 6.125% PRP dilutions. Additionally, it was shown that FBS is not necessary for PRP-mediated induction of osteoblast proliferation. CONCLUSION:This study concluded that PRP promotes osteoblast proliferation and suggested its clinical application to bone graft procedures in implant dentistry.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Ferreira CF,Carriel Gomes MC,Filho JS,Granjeiro JM,Oliveira Simões CM,Magini Rde Sdoi
10.1111/j.1600-0501.2005.01145.xsubject
Has Abstractpub_date
2005-08-01 00:00:00pages
456-60issue
4eissn
0905-7161issn
1600-0501pii
CLR1145journal_volume
16pub_type
杂志文章abstract：OBJECTIVES:The aim of this study was to investigate the osteoconductive properties and biological performance of porous titanium granules used in osseous defects adjacent to titanium implants. MATERIAL AND METHODS:In this animal experimental study, calibrated defects were prepared in the tibias of 24 New Zealand rabbi...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2009.01813.x
更新日期：2010-02-01 00:00:00
abstract：:The principle of guided tissue regeneration was applied in an attempt to generate bone to cover a subperiosteal implant. Titanium frame works, casted on individual impressions of the anterior surface of the tibia of 4 Copenhagen White rabbits, were stabilized to the tibia by microscrews, and half of them were covered ...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.1995.060303.x
更新日期：1995-09-01 00:00:00
abstract：:This study details the structural and ultrastructural features of the interfaces between titanium implants and their surrounding tissues. The material stemmed from an experiment in dogs in which guided tissue regeneration with Gore-Tex membranes was used to treat peri-implant, ligature-induced tissue breakdown around ...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.1994.050201.x
更新日期：1994-06-01 00:00:00
abstract：OBJECTIVES:This study set out to make antibiograms of positive bacteria cultures in samples collected when performing maxillary sinus elevations to determine a specific and effective antibiotic in each case. MATERIAL AND METHODS:A total of 174 patients (90 women and 84 men) with a mean age of 55.92 years underwent 227...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/clr.12835
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVES:This prospective clinical study investigates long-term survival and clinical parameters of non-submerged implants with large buccal dehiscences treated with a deproteinized bovine bone mineral xenograft and a non-resorbable membrane in a one-stage approach. MATERIAL AND METHODS:Sixteen consecutive non-subme...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2005.01154.x
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVES:This prospective multicentre study provides clinical experience up to 3 years to support a simplified treatment for mandibular edentulism within 1 week by using one-stage implant surgery and a screw-retained full-arch bridge. METHODS:Two hundred and fifty ITI Monotype® implants were installed in 62 patients...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2008.01540.x-i2
更新日期：2008-07-01 00:00:00
abstract：:The prosthodontic section of the 1997 ITI Consensus Conference in Vitznau, Switzerland, examined a broad spectrum of issues related to the prosthodontic phase of dental implant therapy. Topics included diagnosis and treatment planning, considerations for the use of ITI prosthodontic components, management of the parti...
journal_title：Clinical oral implants research
pub_type： 共识发展会议,杂志文章,评审
doi：10.1034/j.1600-0501.2000.011s1101.x
更新日期：2000-01-01 00:00:00
abstract：:The aim of this controlled, parallel design clinical study was to compare the effectiveness of an Er:YAG laser (ERL) to that of mechanical debridement using plastic curettes and antiseptic therapy for nonsurgical treatment of peri-implantitis. Twenty patients with moderate to advanced peri-implantitis lesions were ran...
journal_title：Clinical oral implants research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1600-0501.2004.01051.x
更新日期：2005-02-01 00:00:00
abstract：OBJECTIVES:Protocols of immediate loading have been reported in several studies. It has also been demonstrated that the cause of failure of immediate loaded implants is due to the micromotion on the bone-implant interface induced by immediate loading. There should be a minimum gap between the implant and the peri-impla...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2010.02036.x
更新日期：2011-05-01 00:00:00
abstract：:Non-submerged ITI Bonefit implants (ITI Dental Implant System) were inserted in edentulous lower jaws of 46 patients. The patients were provided with either a fixed prosthesis or an overdenture, and has been followed during a 2-year-period. At the 1-year examination, the suprastructures were removed permitting test of...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.1996.070406.x
更新日期：1996-12-01 00:00:00
abstract：OBJECTIVES:To evaluate the accuracy of measuring peri-implant buccal bone when using three different computed tomography devices. MATERIALS AND METHODS:Sixty tissue-level or bone-level dental implants were placed in bovine ribs with either buccal bone full coverage, dehiscence or fenestration. For each site, the dista...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/clr.12663
更新日期：2016-08-01 00:00:00
abstract：OBJECTIVES:As biomaterial-induced modulation of mediators of the immune response may be a potential therapeutic approach to enhance wound healing events, the aim of this study was to delineate the effects of titanium surface modification on macrophage phenotype and function. MATERIAL AND METHODS:Rodent bone marrow-der...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/clr.13522
更新日期：2019-11-01 00:00:00
abstract：:A comparative study of 96 Spline and Threadloc implants is presented. The authors examined the possibility of the failure of the retaining screws of two different antirotational systems (the Threadloc system with hexagonal polyhedral extension and the Spline system), and the possible incorrect link between the abutmen...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.2001.012004319.x
更新日期：2001-08-01 00:00:00
abstract：:The aim of this study was to analyse the clinical outcome of two different surgical methods for the reconstruction of narrow edentulous ridges before implant installation: guided bone regeneration with e-PTFE membranes and autologous bone chips or grafting of autologous bone blocks without e-PTFE membranes. Thirty par...
journal_title：Clinical oral implants research
pub_type： 临床试验,杂志文章
doi：10.1034/j.1600-0501.1999.100404.x
更新日期：1999-08-01 00:00:00
abstract：AIM:The aim of this study was to retrospectively analyze the potential influence of implant inclination on marginal bone loss at freestanding, implant-supported, fixed partial dentures (FPDs) over a 5-year period of functional loading. MATERIAL AND METHODS:The material comprised 38 periodontally treated, partially den...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2007.01386.x
更新日期：2007-10-01 00:00:00
abstract：:The information concerning the molecular events taking place in onlay bone grafts are still incipient. The objective of the present study is to correlate the effects of perforation of resident bone bed on (1) the timing of onlay autogenous graft revascularization; (2) the maintenance of volume/density of the graft (as...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2007.01485.x
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVES:A prospective double-blind randomised controlled trial was conducted to test the effect of prophylactic antibiotics on post-operative morbidity and osseointegration of dental implants. MATERIALS AND METHODS:Fifty-five subjects scheduled for implant surgery were enrolled. The patients were randomly assigned ...
journal_title：Clinical oral implants research
pub_type： 杂志文章,随机对照试验
doi：10.1111/clr.12124
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVES:This study was conducted to evaluate the effect of barrier membranes on sandwich bone augmentation (SBA) for the treatment of implant dehiscence defects. MATERIAL AND METHODS:Twenty-six implant-associated buccal dehiscence defects in 22 patients were treated according to the SBA concept - mineralized human ...
journal_title：Clinical oral implants research
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-0501.2007.01408.x
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVE:To analyze the outcomes of static computer-aided implant placement (sCAIP) compared to partially guided (PGIP) and free-handed (FHIP) implant placement. MATERIAL AND METHODS:This study was registered in PROSPERO (CRD42019131397). A comprehensive literature search was performed by two independent examiners. O...
journal_title：Clinical oral implants research
pub_type： 杂志文章,meta分析
doi：10.1111/clr.13635
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to investigate the effects of a nanostructured calcium coating on the surfaces of blasted Ti implants on peri-implant bone formation in the rabbit tibiae. MATERIAL AND METHODS:Threaded implants (3.75 mm in diameter, 6 mm in length) were roughened by hydroxyapatite (HA) blasting ...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2006.01323.x
更新日期：2007-06-01 00:00:00
abstract：:This paper reports on a 7-year life table analysis on ITI titanium plasma-sprayed (TPS) and sandblasted and etched (SLA) implants placed in a private practice and loaded for at least 1 year. In 236 patients, 528 (264 TPS and 264 SLA) implants were placed, 351 (66.5%) implants rehabilitated the posterior region and 71....
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2004.00978.x
更新日期：2004-04-01 00:00:00
abstract：PURPOSE:The purpose of this prospective study on humans were to evaluate (a) the clinical outcome of alveolar distraction osteogenesis for the correction of vertically deficient edentulous mandibular ridges, (b) the clinical outcome of dental implants placed in the distracted areas, and (c) the quality and quantity of ...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2005.01247.x
更新日期：2006-08-01 00:00:00
abstract：AIM:To investigate bone-to-implant bonding for some novel surface modifications with a hierarchic structure and to correlate the in vivo results with surface roughness parameters. MATERIALS AND METHODS:Newly developed implants surfaces were tested in rabbits and compared with the commercially available OsseoSpeed™ (OS...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2011.02233.x
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVES:A removable implant-retained dental prosthesis in an edentulous mandible can use telescopic crowns or a bar superstructure as anchorage elements for an overdenture. The aim of this study was to compare the clinical results for bar-anchored and telescopic crown-retained overdentures in implant prosthetic trea...
journal_title：Clinical oral implants research
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-0501.2007.01500.x
更新日期：2008-05-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to assess the clinical success of dental implants placed in severely atrophic maxilla (residual bone height ≤4 mm) using transalveolar sinus floor elevation (TSFE) without grafting. Furthermore, the implant stability during the healing period was also evaluated. MATERIALS AND METHOD...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/clr.12547
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVES:The present study aimed at evaluating the marginal bone resorption and the peri-implant tissue conditions around Narrow-Neck ITI implants in the implant-prosthetic treatment of the agenesis of maxillary lateral incisors. MATERIAL AND METHODS:Thirty patients affected by monolateral or bilateral agenesis of t...
journal_title：Clinical oral implants research
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-0501.2005.01188.x
更新日期：2006-02-01 00:00:00
abstract：PURPOSE:The aim of this prospective study was to evaluate the soft tissue changes around implants in the aesthetic zone, placed under a trimodal approach (immediate post-extraction placement, flapless, and immediate provisional restoration) and its relationship to gingival/periodontal biotype of the patient. MATERIALS...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1111/j.1600-0501.2012.02516.x
更新日期：2013-10-01 00:00:00
abstract：:A dog model for study of supracrestal bone growth around partially inserted implants is described. The mandibular premolar teeth (P1, P2, P3 and P4) were extracted on both sides of the mandible in four dogs. At a surgical exposure 12 weeks later, two 10 mm titanium implants were partially inserted on each side, 15 mm ...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.2002.130502.x
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVE:To review systematically whether supportive implant treatment during a follow-up of at least 10 years after functional loading is effective in prevention of biological complications and fixture loss. METHODS:A MEDLINE search was conducted for the period of 1965 to April 2006 of longitudinal clinical studies ...
journal_title：Clinical oral implants research
pub_type： 杂志文章,评审
doi：10.1111/j.1600-0501.2007.01447.x
更新日期：2007-06-01 00:00:00
abstract：:In 8 monkeys both the maxillary lateral incisors were extracted. In the 16 extraction sites an Al2O3-ceramic dental implant (Frialit) was immediately inserted. Eight implants were submerged under the oral mucosa and the other 8 were allowed to penetrate through the mucosa during the observation period. None of the imp...
journal_title：Clinical oral implants research
pub_type： 杂志文章
doi：10.1034/j.1600-0501.1995.060206.x
更新日期：1995-06-01 00:00:00
