Abstract:
OBJECTIVE:In the present study, a new healing cap that could generate a pulsed electromagnetic field (PEMF) around titanium implants to stimulate peri-implant osteogenesis was tested in the rabbit model. MATERIALS AND METHODS:A total of 22 implants were inserted in the proximal tibial metaphysis of 22 rabbits. A healing cap containing the active device was inserted in half of the implants (11 test implants); an "empty" healing cap was inserted in the other ones (11 control implants). The animals were euthanized after 2 and 4 weeks, and the samples were processed for micro-computed tomography and histology. The peri-implant volume was divided into coronal (where the PEMF was the strongest) and apical regions. RESULTS:Most of the effects of the tested device were confined to the coronal region. Two weeks post-implantation, test implants showed a significant 56% higher trabecular bone fraction (BV/TV), associated with enhanced trabecular number (Tb.N, +37%) and connectivity density (Conn.D, +73%) as compared to the control group; at 4 weeks, the PEMF induced a 69% increase in BV/TV and 34% increase of Tb.N. There was no difference in the trabecular thickness (Tb.Th) at either time point. Furthermore, we observed a 48% higher bone-to-implant contact (BIC) in the test implants vs. controls after 2 weeks; this increase tended to remain stable until the fourth week. Mature trabecular and woven bone were observed in direct contact with the implant surface with no gaps or connective tissue at the bone-implant interface. CONCLUSIONS:These results indicate that the PEMF device stimulated early bone formation around dental implants resulting in higher peri-implant BIC and bone mass already after 2 weeks which suggests an acceleration of the osseointegration process by more than three times.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Barak S,Neuman M,Iezzi G,Piattelli A,Perrotti V,Gabet Ydoi
10.1111/clr.12661subject
Has Abstractpub_date
2016-08-01 00:00:00pages
935-42issue
8eissn
0905-7161issn
1600-0501journal_volume
27pub_type
杂志文章abstract:OBJECTIVE:To evaluate the influence of the configuration of the marginal aspect of implants placed immediately into extraction sockets on peri-implant hard tissue adaptation. MATERIAL AND METHODS:In 6 Labrador dogs, endodontic treatments of the mesial roots of 1 M1 were performed and the distal roots were removed. 2 P...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12262
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:The purpose of the present prospective follow-up study was to evaluate the long-term influence of the peri-implant keratinized mucosa (KM) on marginal bone level (MBL), peri-implant tissues health, and brushing discomfort. MATERIAL AND METHODS:Eighty patients were initially recruited during their maintenance...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13381
更新日期:2018-12-01 00:00:00
abstract:AIM:To test whether an equine bone substitute block used for guided bone regeneration (GBR) of peri-implant defects differs from bovine block or particulate bone substitutes regarding the hard and soft tissue contours of the augmented ridge. MATERIAL & METHODS:Two semi-saddle bone defects were prepared in each side of...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13011
更新日期:2017-11-01 00:00:00
abstract::The prosthodontic section of the 1997 ITI Consensus Conference in Vitznau, Switzerland, examined a broad spectrum of issues related to the prosthodontic phase of dental implant therapy. Topics included diagnosis and treatment planning, considerations for the use of ITI prosthodontic components, management of the parti...
journal_title:Clinical oral implants research
pub_type: 共识发展会议,杂志文章,评审
doi:10.1034/j.1600-0501.2000.011s1101.x
更新日期:2000-01-01 00:00:00
abstract::The 15 patients included in this study each had 2-6 permucosal Branemark osseointegrated implants that had functioned successfully for 18 months or more. They were given a full oral examination which included measurements of probing depth and gingival, bleeding and plaque indices around the implants. Marginal bone red...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1991.020203.x
更新日期:1991-04-01 00:00:00
abstract:OBJECTIVES:The aims of this study were (i) to evaluate the efficacy of ridge preservation and repair procedures involving the application of SocketKAP(™) and SocketKAGE(™) devices following tooth removal and (ii) to evaluate alveolar bone volumetric changes at 6 months post-extraction in intact sockets or those with fa...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12687
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:Retrospectively, we assessed the likelihood that peri-implantitis was associated with a history of systemic disease, periodontitis, and smoking habits. METHODS:Data on probing pocket depth (PPD), bleeding on probing (BOP), and radiographic bone levels were obtained from individuals with dental implants. Per...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12208
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:The aim of this prospective clinical trial was to assess clinical, radiological, and esthetic outcomes of immediate-loaded post-extractive implants after 1 year of follow-up. MATERIALS AND METHODS:Twenty-four consecutive patients (15 females and nine males) with a mean age of 47.27 years (range 35-65) requirin...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1111/clr.12403
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVES:The aim of this prospective, randomized clinical trial was to investigate the potential of recombinant human growth and differentiation factor-5 (rhGDF-5) coated onto β-tricalcium phosphate (β-TCP) (rhGDF-5/β-TCP) to support bone formation after sinus lift augmentation. MATERIAL AND METHODS:In total, 31 pat...
journal_title:Clinical oral implants research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1600-0501.2010.01949.x
更新日期:2010-11-01 00:00:00
abstract::Non-submerged ITI Bonefit implants (ITI Dental Implant System) were inserted in edentulous lower jaws of 46 patients. The patients were provided with either a fixed prosthesis or an overdenture, and has been followed during a 2-year-period. At the 1-year examination, the suprastructures were removed permitting test of...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1996.070406.x
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVE:The aim of this systematic review was to investigate the influence of bone mineral density on the primary stability of dental implants. MATERIAL AND METHODS:A search of health science databases (Cochrane Library, MEDLINE-PubMed, ISI Web of Knowledge, EMBASE, LILACS) and grey literature was performed, includi...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2011.02228.x
更新日期:2012-07-01 00:00:00
abstract::This paper reports on a 7-year life table analysis on ITI titanium plasma-sprayed (TPS) and sandblasted and etched (SLA) implants placed in a private practice and loaded for at least 1 year. In 236 patients, 528 (264 TPS and 264 SLA) implants were placed, 351 (66.5%) implants rehabilitated the posterior region and 71....
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.00978.x
更新日期:2004-04-01 00:00:00
abstract::Bovine mineral spongiosa block (B-SB) was used as a bone substitute in sinus augmentation procedures in 10 consecutive patients. Implants were placed during the same session. The purpose of this study was to histopathologically examine the healing of the grafted site around the implants at 12 months. Radiographic foll...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130411.x
更新日期:2002-08-01 00:00:00
abstract::The information concerning the molecular events taking place in onlay bone grafts are still incipient. The objective of the present study is to correlate the effects of perforation of resident bone bed on (1) the timing of onlay autogenous graft revascularization; (2) the maintenance of volume/density of the graft (as...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01485.x
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVES:To compare ear, nose, and throat (ENT) specialists and dentists assessing health or pathology of maxillary sinuses using cone beam computed tomography (CBCT). MATERIAL AND METHODS:Two ENT specialists and two oral surgeons assessed 100 CBCT datasets of healthy patients referred for dental implant placement i...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13582
更新日期:2020-05-01 00:00:00
abstract:AIM:The aim of the present study was to analyze tissue reactions to plaque formation following ligature removal in experimental peri-implantitis at commercially available implants in dogs. MATERIAL AND METHODS:Mandibular premolars and the three anterior premolars in both sides of the maxilla were extracted in six Labr...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01645.x
更新日期:2009-04-01 00:00:00
abstract:AIM:This study compared the effects of Escherichia-coli-produced recombinant human bone morphogenetic protein 2 (ErhBMP-2) with a biphasic calcium phosphate (BCP) carrier to those of deproteinized bovine bone in human maxillary sinus floor augmentation. MATERIAL AND METHODS:Screening for this clinical trial selected 5...
journal_title:Clinical oral implants research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/clr.12471
更新日期:2015-12-01 00:00:00
abstract:AIM:The objective of the study was to compare (i) esthetic, (ii) clinical and (iii) patient-centered outcomes following immediate (Type 1) and early implant placement (Type 2). MATERIAL AND METHODS:Thirty-eight subjects needing a single extraction (premolar to premolar) were randomly allocated to Type 1 or Type 2 impl...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12577
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:The aim of this clinical study was to evaluate long-term outcomes of implant therapy in a cohort of immunosuppressed renal transplant patients compared with a matched control group. MATERIAL AND METHODS:Pharmacologically immunosuppressed renal transplant patients received dental implant treatment between 20...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13437
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVES:To describe the early biofilm formation over whole dental implants with its micro- and macrostructure, using an in vitro multispecies biofilm model. MATERIAL AND METHODS:Six bacterial strains (Streptococcus oralis, Actinomyces naeslundii, Veillonella parvula, Fusobacterium nucleatum, Porphyromonas gingivali...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13409
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:During the fourth Summer Camp (SC) held by the European Association of Osseointegration (EAO), 20 junior representatives from various European and non-European universities and associations were selected to partake in oral presentation and communication skill development. AIMS:The aim of the EAO Summer Camp...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13625
更新日期:2020-08-01 00:00:00
abstract::The principle of guided tissue regeneration was applied in an attempt to generate bone to cover a subperiosteal implant. Titanium frame works, casted on individual impressions of the anterior surface of the tibia of 4 Copenhagen White rabbits, were stabilized to the tibia by microscrews, and half of them were covered ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1995.060303.x
更新日期:1995-09-01 00:00:00
abstract::This study compared osteoblasts proliferation, differentiation, and protein synthesis on new and used titanium (Ti) disks to test the hypothesis that cleaning and resterilization of previously used Ti disks does not alter cell response to a particular surface. Ti disks of varying roughness were prepared by one of five...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1996.070104.x
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVES:The aim of the present publication was to report on the EAO Workshop group-4 discussions and consensus statements on the five reviews previously prepared. These reviews provided the scientific evidence on the effect of crown-to-implant ratio, on reconstructions with cantilevers in fully and partially edentul...
journal_title:Clinical oral implants research
pub_type: 共识发展会议,杂志文章
doi:10.1111/clr.13284
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:The aim of this crossover study was to compare clinical denture base deformation with different attachments used for mandibular implant overdentures. MATERIALS AND METHODS:Twenty-four patients with edentulous mandibular ridges received two implants in the former canine regions. Three months thereafter, each...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13552
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:We hypothesized that a biomimetic calcium phosphate (CaP) coating which incorporates morphogenetic protein 2 (BMP-2) on the deproteinized bovine bone (DBB) blocks could be used to enhance the vertical alveolar ridge augmentation for the one-stage onlay surgery with simultaneous implants insertion. We aimed to...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13558
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:This prospective multicentre study provides clinical experience up to 3 years to support a simplified treatment for mandibular edentulism within 1 week by using one-stage implant surgery and a screw-retained full-arch bridge. METHODS:Two hundred and fifty ITI Monotype® implants were installed in 62 patients...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01540.x-i2
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVES:To analyze the relationships between peri-implant conditions and periodontal conditions in Chinese patients with dental implants in place for at least 1 year. MATERIAL AND METHODS:Seventy-six patients (mean age, 41 ± 10 years; range, 21-69 years) who received placement of 120 dental implants (Straumann(®) )...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12114
更新日期:2014-03-01 00:00:00
abstract::Bone anchored implants are now being used in dentistry for supporting intraoral and craniofacial prostheses. Although high success rates have been reported, a small number of implants may fail during the early healing phase or lateral in function. Currently available clinical methods to determine implant stability and...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1996.070308.x
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVES:This study set out to make antibiograms of positive bacteria cultures in samples collected when performing maxillary sinus elevations to determine a specific and effective antibiotic in each case. MATERIAL AND METHODS:A total of 174 patients (90 women and 84 men) with a mean age of 55.92 years underwent 227...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12835
更新日期:2018-11-01 00:00:00