Abstract:
:The 15 patients included in this study each had 2-6 permucosal Branemark osseointegrated implants that had functioned successfully for 18 months or more. They were given a full oral examination which included measurements of probing depth and gingival, bleeding and plaque indices around the implants. Marginal bone reduction during the functional life of the implants was estimated from radiographs. At a separate visit, peri-implant sulcus fluid (PISF) was collected on filter paper strips from the deepest probing site of each implant. PISF volumes were measured and the samples eluted into buffer. Protease activities in the eluates were determined by fluorimetric assay with peptidyl derivatives of 7-amino-4-trifluoromethyl coumarin. Enzyme levels followed the order: cathepsin B/L greater than elastase greater than dipeptidyl peptidase IV greater than trypsin-like activity. Total enzyme activities and concentrations both correlated positively with all clinical parameters in linear regression analysis. This was true on both a patient level using mean patient values and a site level using pooled patient data. Nearly all of the site level correlations were statistically significant, though coefficients were generally higher for total enzyme activities than concentrations. Elastase-like activity gave the best overall correlations of the different proteases measured. Amongst the clinical parameters, correlations were generally best with gingival index and bone reduction. Total enzyme activities had good diagnostic specificity and sensitivity as predictors of clinical parameters and the figures were especially high for elastase-like activity as a marker of bone reduction. PISF proteases may thus be of value in monitoring tissue responses to osseointegrated implants.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Eley BM,Cox SW,Watson RMdoi
10.1034/j.1600-0501.1991.020203.xsubject
Has Abstractpub_date
1991-04-01 00:00:00pages
62-70issue
2eissn
0905-7161issn
1600-0501journal_volume
2pub_type
杂志文章abstract:OBJECTIVES:As biomaterial-induced modulation of mediators of the immune response may be a potential therapeutic approach to enhance wound healing events, the aim of this study was to delineate the effects of titanium surface modification on macrophage phenotype and function. MATERIAL AND METHODS:Rodent bone marrow-der...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13522
更新日期:2019-11-01 00:00:00
abstract:AIMS/BACKGROUND:Empirically, for implant placement associated with sinus floor augmentation, a minimum of five mm of residual crestal bone height has been recommended in order to achieve sufficient initial implant stability. It has been the aim of the study to test this assumption in an experimental animal trial. MATE...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01570.x
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Minimizing crestal bone loss following immediate implant placement is considered the most challenging aspect in implant therapy. Implant surface topography and chemical modifications have been shown to influence the success of Osseointegration. The Straumann Bone Level implant, featuring SLActive surface, ha...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12388
更新日期:2015-09-01 00:00:00
abstract::The aim of this study was to investigate whether a new connective tissue attachment can occur on a surface of hydroxyapatite (HA) when periodontal ligament (PDL)-derived cells with the ability to form new connective tissue attachment are allowed to populate the surface of HA. Six maxillary canines from 3 cats were use...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1993.040303.x
更新日期:1993-09-01 00:00:00
abstract:AIM:To review the literature on the prevalence and incidence of peri-implantitis. METHODS:Out of 322 potentially relevant publications we identified 29 articles concerning 23 studies, with information on the presence of signs of peri-implantitis in populations of at least 20 cases. RESULTS AND CONCLUSIONS:All studies...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2012.02541.x
更新日期:2012-10-01 00:00:00
abstract::The presence of certain glycosaminoglycans in peri-implant sulcus fluid may be an effective means of monitoring changes in bone metabolic activity following initial loading of implant abutments. This study has investigated levels of chondroitin 4 sulphate and hyaluronan in peri-implant sulcus fluid from titanium osseo...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1991.020404.x
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVE:In a prospective pilot study, short< or =10 mm ITI-SLA implants were placed in the resorbed posterior maxilla by means of an osteotome sinus floor elevation (OSFE) procedure without grafting material. This paper presents 3-year data assessing bone-level changes around implants. MATERIAL AND METHODS:Twenty-fi...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01696.x
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVES:The aim of this clinical study was to evaluate long-term outcomes of implant therapy in a cohort of immunosuppressed renal transplant patients compared with a matched control group. MATERIAL AND METHODS:Pharmacologically immunosuppressed renal transplant patients received dental implant treatment between 20...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13437
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:This retrospective study was set to assess the influence of systemic and local bone and intra-oral factors on the occurrence of implant loss from abutment connection up to 2 years. MATERIALS AND METHODS:The files of 700 patients, have been collected randomly from the total patient group treated by means of ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01534.x
更新日期:2008-07-01 00:00:00
abstract::Although a two-stage procedure with symphyseal oral implants can lead to a long-term (15 years) 99% cumulative survival rate, a one-stage approach with immediate loading via prefabricated elements seems to offer a short-term acceptable outcome with significantly lower costs. A series of 50 consecutive patients, not el...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.01069.x
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:There are various alternatives for the management of oral conditions that may lead to or already have lead to partial or full edentulism. Economic evaluations measure the efficiency of alternative healthcare interventions and provide useful information for decision-making and the allocation of scarce resource...
journal_title:Clinical oral implants research
pub_type: 共识发展会议,杂志文章,评审
doi:10.1111/clr.12630
更新日期:2015-09-01 00:00:00
abstract::The study aimed to examine the relationship between the subgingival flora around implants and their periodontal parameters. Plaque samples from 561 implants (279 patients) were analyzed by means of differential phase contrast microscopy and compared with the sample site's probing depth, bleeding tendency on probing, a...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1995.060401.x
更新日期:1995-12-01 00:00:00
abstract:BACKGROUND:Alumina-toughened zirconia (ATZ) is a possible alternative material to titanium for oral implants. No data are available on the fracture strength of ATZ oral implants. PURPOSE:The purpose of this study was to examine one-piece implants made of ATZ ceramic under artificial loading conditions and to compare t...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.01954.x
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVES:The purpose of the present study was to evaluate the survival rate of dental implants in previously failed implant sites. In addition, factors that might affect the outcome of these redo procedures were also explored. MATERIAL AND METHODS:Patients that had failed dental implants, which were replaced with th...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01466.x
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVES:Guided bone regeneration (GBR) is a commonly utilized surgical technique in the craniofacial region. The transcriptional mechanisms associated with this type of bone regeneration are not well understood. The aim of this study was to characterize the transcriptome associated with GBR of a critical-size calvar...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02104.x
更新日期:2011-04-01 00:00:00
abstract:AIM OF THE STUDY:To present the results of a prospective study on the management of infectious complications following maxillary sinus floor elevation procedures with a combined endoscopic (FESS) and intra-oral approach. MATERIALS AND METHODS:From 2005 to 2009, twenty consecutive patients were diagnosed for sinusal ch...
journal_title:Clinical oral implants research
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1600-0501.2012.02440.x
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVES:In regenerative medicine, surface engineering of bioinert synthetic materials is often required in order to introduce bioactive species that can promote cell adhesion, proliferation, viability and enhanced ECM-secretion functions. The aim of this work is to study cell interaction with alumina-modified surfac...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01642.x
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVES:To evaluate the potential influence of different cone-beam computed tomography (CBCT) devices on the transfer accuracy of an open-source system for computer-aided implantology (CAI). MATERIAL AND METHODS:A total of 108 implants in 18 partially edentulous patient-equivalent models were planned and fully guid...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02272.x
更新日期:2012-09-01 00:00:00
abstract:AIM:This study sought to investigate dimensional changes to the alveolar bone following extraction and application of novel devices used for obturation of socket orifice (socket cap) and space maintenance in sockets with facial dehiscence (socket cage). MATERIAL AND METHODS:Six Macaca fascicularis had six teeth each r...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12521
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:Published information regarding the use of rat jawbones for dental implant osseointegration research is limited and often inconsistent. This study assessed the suitability and feasibility of placing dental implants into the rat maxilla and to establish parameters to be used for dental implant research using ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12571
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:To assess the impact of collagen membrane application on bone formation surrounding implants placed simultaneously with the bone ring technique. MATERIAL AND METHODS:Dental implants were inserted simultaneously with the bone ring technique in standardized, vertical alveolar bony defects in the mandible of d...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13543
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:The aims of this study were (i) to evaluate the efficacy of ridge preservation and repair procedures involving the application of SocketKAP(™) and SocketKAGE(™) devices following tooth removal and (ii) to evaluate alveolar bone volumetric changes at 6 months post-extraction in intact sockets or those with fa...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12687
更新日期:2016-06-01 00:00:00
abstract::Sinus augmentation has been advocated to be a surgical technique with predictable results in peri-implant surgery. Endoscopic surgery of the maxillary sinus so far has been used as diagnostic procedure. In this paper, the use of endoscopy is described as a low invasive adjunctive technique in sinus floor augmentation....
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1997.080612.x
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:Information of implant periapical lesion(IPL) is insufficient by now. The aim of this review is to analyze the possible causes of IPL and to find out the proper treatment protocol. MATERIAL AND METHODS:A systematic literature search was carried out (up to June 2012) using relevant search terms in PUBMED. And...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/clr.12232
更新日期:2014-09-01 00:00:00
abstract:AIM:To investigate bone-to-implant bonding for some novel surface modifications with a hierarchic structure and to correlate the in vivo results with surface roughness parameters. MATERIALS AND METHODS:Newly developed implants surfaces were tested in rabbits and compared with the commercially available OsseoSpeed™ (OS...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02233.x
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of enamel matrix derivative in liquid form (EMD-liquid) as adjunct to grafting with natural bovine bone (NBB), on new bone formation and osseointegration in buccal dehiscence defects at dental implants. MATERIAL AND METHODS:In six beagles, 3 months after extraction of the mandibular p...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13512
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:There is limited knowledge regarding the strength of zirconia abutments with internal and external implant abutment connections and zirconia abutments supported by a titanium resin base (Variobase, Straumann) for narrow diameter implants. OBJECTIVES:To compare the fracture strength of narrow diameter abutme...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13139
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:To use cone beam computed tomography (CBCT) to assess the alterations of socket dimensions after a 6-month healing period following molar extraction. MATERIALS AND METHODS:Seventeen molars were extracted due to advanced periodontitis. CBCT scans were taken immediately after extraction and once more 6 months ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13418
更新日期:2019-04-01 00:00:00
abstract::This study compared osteoblasts proliferation, differentiation, and protein synthesis on new and used titanium (Ti) disks to test the hypothesis that cleaning and resterilization of previously used Ti disks does not alter cell response to a particular surface. Ti disks of varying roughness were prepared by one of five...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1996.070104.x
更新日期:1996-03-01 00:00:00
abstract:INTRODUCTION:Maxillary sinus augmentation is a predictable implant site development technique, although several local and systemic factors may influence outcomes. The aim of this study was to evaluate healing patterns and bone remodeling activity following the use of two different graft mixtures for maxillary sinus aug...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0501.2010.02073.x
更新日期:2011-08-01 00:00:00