Abstract:
OBJECTIVES:To describe the early biofilm formation over whole dental implants with its micro- and macrostructure, using an in vitro multispecies biofilm model. MATERIAL AND METHODS:Six bacterial strains (Streptococcus oralis, Actinomyces naeslundii, Veillonella parvula, Fusobacterium nucleatum, Porphyromonas gingivalis, and Aggregatibacter actinomycetemcomitans) were used to develop in vitro biofilms over whole titanium implants (growth times 12, 24, 48, 72, 96, and 120 hr). The morphology of biofilms was studied by confocal laser scanning microscopy and scanning electron microscopy, and the bacterial dynamics through quantitative polymerase chain reaction. As primary outcome variable, numbers of each species [colony-forming units per milliliter (CFU/ml)] at different incubation times were compared using the one-way analysis of variance and post hoc testing with Bonferroni's correction. Furthermore, implants were fixed in methacrylate stents to reproduce the clinical situation and biofilms were developed and analyzed by scanning electron microscopy. RESULTS:Bacteria colonized implants in a short period of time. Biofilms reached a mature state at 96 hr, exhibiting different ratios of live/dead cells depending on their location, being the peaks of the threads the areas harboring more live bacteria. The densities of each bacteria fluctuated in time, reaching its maximum at 96 hr. Even though the coefficients of variation were high, percentages were similar to those published previously using implant surface specimens, rather than whole implants. CONCLUSION:Dental implants can be colonized by different bacterial species, developing into a mature and well-structured biofilm, which depending on the location may exhibit different degree of bacterial vitality.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Bermejo P,Sánchez MC,Llama-Palacios A,Figuero E,Herrera D,Sanz Mdoi
10.1111/clr.13409subject
Has Abstractpub_date
2019-03-01 00:00:00pages
229-241issue
3eissn
0905-7161issn
1600-0501journal_volume
30pub_type
杂志文章abstract:AIM:The aim of this clinical trial was to evaluate the safety and efficiency of a one-piece zirconia oral implant after 1 year of function. MATERIALS AND METHODS:Two centers included 60 subjects in need of implant-supported single-tooth restorations or three-unit bridges. A total of 71 zirconia one-piece implants were...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/clr.12670
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:Primary implant stability is related to local bone density. After insertion of an implant, implant stability is subject to changes due to bone remodeling. In patients who have undergone radiotherapy in the head and neck region, implant stability is impaired because irradiation reduces bone vitality. The curr...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01457.x
更新日期:2008-02-01 00:00:00
abstract::The aim of the present study was to evaluate the soft tissue response to intra-orally exposed and contaminated titanium surfaces (machined, blasted or polished) after being chemically and/or mechanically cleaned. Eight adult Sprague-Dawley rats were used for histomorphometrical and histological analyses. A total of 44...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2000.011004370.x
更新日期:2000-08-01 00:00:00
abstract::For certain surgical procedures (e.g. placement of implants), an accurate localisation of the mandibular canal is of utmost importance to avoid injuries to the neurovascular bundle. The aim of the present study was to evaluate, on human fresh cadavers (n = 6), the accuracy of conventional spiral tomography for the loc...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2001.012003230.x
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND/AIMS:Clinical probing of the soft tissues around oral implants has become a frequently used parameter for clinical monitoring. However, the healing of the disruption of the soft tissue seal as a result of probing has not yet been studied. The purpose of this study was to evaluate the healing events in the pe...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130601.x
更新日期:2002-12-01 00:00:00
abstract:AIM:This study sought to investigate dimensional changes to the alveolar bone following extraction and application of novel devices used for obturation of socket orifice (socket cap) and space maintenance in sockets with facial dehiscence (socket cage). MATERIAL AND METHODS:Six Macaca fascicularis had six teeth each r...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12521
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:To review the literature on mandibular single-implant overdentures (opposing complete maxillary dentures), and present surgical and prosthodontic perspectives of a novel approach for this treatment option. MATERIAL AND METHODS:An electronic search through the databases of Pubmed, Embase and Medline using th...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2008.01666.x
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVES:The aim was to evaluate the peri-implant tissue levels over a 1-year period for implants connected to either convex or concave final abutments at the time of implant placement. MATERIALS AND METHODS:In this randomized, double masked, controlled clinical study, twenty-eight patients with one missing maxillar...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13493
更新日期:2019-09-01 00:00:00
abstract:AIM:To investigate bone-to-implant bonding for some novel surface modifications with a hierarchic structure and to correlate the in vivo results with surface roughness parameters. MATERIALS AND METHODS:Newly developed implants surfaces were tested in rabbits and compared with the commercially available OsseoSpeed™ (OS...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02233.x
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:A precise and scientifically established method for the evaluation of the bone quality/primary stability is the measure of the insertion torque (IT). The aim of this study was a comparison between the IT values and the bone-implant contact percentage (BIC) of human implants retrieved after a 4/8-week healing ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01599.x
更新日期:2009-08-01 00:00:00
abstract::Although a two-stage procedure with symphyseal oral implants can lead to a long-term (15 years) 99% cumulative survival rate, a one-stage approach with immediate loading via prefabricated elements seems to offer a short-term acceptable outcome with significantly lower costs. A series of 50 consecutive patients, not el...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.01069.x
更新日期:2004-06-01 00:00:00
abstract::The present study describes the use of unbiased stereological methods for the quantitative evaluation of the amount of regenerated bone. Using the principle of guided bone regeneration the amount of regenerated bone after placement of degradable or non-degradable membranes covering defects in rabbit calvaria was compa...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1998.090303.x
更新日期:1998-06-01 00:00:00
abstract::This study aimed to investigate the effect of hyperbaric oxygen (HBO) therapy on the tissue reactions to commercially pure (c.p.) titanium implants placed in free autogenous bone graft by a 1-stage procedure. Eighty c.p. titanium implants were placed in the bone grafted from iliac crest to bilateral mandible of 40 Jap...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1996.090604.x
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVES:To appraise the feasibility of loading four implants with a pre-existing denture converted to a fixed dental prosthesis (FDP) on the day of implant surgery compared with waiting for 3- to 4-month healing. METHODS:Patients with an edentulous, fully healed mandible were recruited in a faculty clinic to partak...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12279
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to radiologically and histologically evaluate the graft healing and volumetric changes after lateral augmentation with two different compositions of deproteinized bovine bone (DPBB) and autogenous bone (AB). MATERIAL AND METHODS:Thirteen patients with a mean age of 59.6 ± 12.1 years ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12143
更新日期:2014-03-01 00:00:00
abstract::Bovine mineral spongiosa block (B-SB) was used as a bone substitute in sinus augmentation procedures in 10 consecutive patients. Implants were placed during the same session. The purpose of this study was to histopathologically examine the healing of the grafted site around the implants at 12 months. Radiographic foll...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130411.x
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVE:The purpose of the present prospective follow-up study was to evaluate the long-term influence of the peri-implant keratinized mucosa (KM) on marginal bone level (MBL), peri-implant tissues health, and brushing discomfort. MATERIAL AND METHODS:Eighty patients were initially recruited during their maintenance...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13381
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to explore effects of implant macrodesign and diameter on initial intraosseous stability and interface mechanical properties of immediately placed implants. MATERIAL AND METHOD:Mandibular premolars of four fresh-frozen human cadavers were extracted. Ø 4.1/4.8 mm ITI TE, Ø 4.1 ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.01099.x
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVES:The aim of the present multi-center study was to evaluate the treatment outcome of immediately restored one-piece single-tooth implants with a diameter of 3 mm after 1 year. MATERIAL AND METHODS:A total of 57 one-piece implants (NobelDirect 3.0) were inserted in 47 patients (26 females, 21 males) with a mea...
journal_title:Clinical oral implants research
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1600-0501.2011.02174.x
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the early cellular attachment and viability to modified polyethylene glycol (PEG) hydrogels with the influence of arginine-glycine-aspartic acid (RGD) in an in vitro model system. MATERIAL AND METHODS:Human gingival fibroblasts (HGF-1) were cultured on 6 different modalities of PEG hydrogel in h...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12076
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:To compare ear, nose, and throat (ENT) specialists and dentists assessing health or pathology of maxillary sinuses using cone beam computed tomography (CBCT). MATERIAL AND METHODS:Two ENT specialists and two oral surgeons assessed 100 CBCT datasets of healthy patients referred for dental implant placement i...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13582
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVES:To retrospectively evaluate the conditions of the peri-implant tissues in treated patients with chronic periodontitis (CP) and in patients without chronic periodontitis (noCP). MATERIALS AND METHODS:A chart review was used to evaluate 267 implants, 134 placed in 42 CP treated patients and 133 placed in 46 n...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13712
更新日期:2021-01-16 00:00:00
abstract:OBJECTIVES:Protocols of immediate loading have been reported in several studies. It has also been demonstrated that the cause of failure of immediate loaded implants is due to the micromotion on the bone-implant interface induced by immediate loading. There should be a minimum gap between the implant and the peri-impla...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02036.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:Minor sinus floor elevation is a method with relatively high predictability but is technically demanding. Improvement of the technique and increase in the predictability are desirable. MATERIAL AND METHODS:A clinical protocol for minor sinus floor elevation with SLA-ITI (large grit acid-etched implants with...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01161.x
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:After implant insertion and loading, crestal bone usually undergoes remodeling and resorption. If the horizontal relationship between the outer edge of the implant and a smaller-diameter component ('platform switching') is altered, there seems to be reduced crestal bone loss. Immediate loading allows immedia...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01449.x
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to determine the relationship between patients with a history of periodontitis and development of cement-related peri-implant disease. MATERIALS AND METHODS:Seventy-seven patients with 129 implants for this retrospective analysis were selected from completed implant cases that ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02570.x
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:There is limited knowledge regarding the strength of zirconia abutments with internal and external implant abutment connections and zirconia abutments supported by a titanium resin base (Variobase, Straumann) for narrow diameter implants. OBJECTIVES:To compare the fracture strength of narrow diameter abutme...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13139
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:Recent studies have suggested that magnesium (Mg) ions exert a beneficial effect on implant osseointegration. This study assessed the osseointegration of nanoporous titanium (Ti) surface incorporating the Mg produced by hydrothermal treatment in rabbit cancellous bone to determine whether this surface would f...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02144.x
更新日期:2012-03-01 00:00:00
abstract::Microbial plaque accumulation on titanium dental implant surfaces can result in an inflammatory condition of the surrounding tissues. Cleaning of such a contaminated surface, in vivo, by means of a solution of amino-alcohol, following surgical exposure, has been proposed. However, the tissue healing following treatmen...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1999.100303.x
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess the clinical success of dental implants placed in severely atrophic maxilla (residual bone height ≤4 mm) using transalveolar sinus floor elevation (TSFE) without grafting. Furthermore, the implant stability during the healing period was also evaluated. MATERIALS AND METHOD...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12547
更新日期:2016-01-01 00:00:00