Abstract:
OBJECTIVES:To evaluate the early cellular attachment and viability to modified polyethylene glycol (PEG) hydrogels with the influence of arginine-glycine-aspartic acid (RGD) in an in vitro model system. MATERIAL AND METHODS:Human gingival fibroblasts (HGF-1) were cultured on 6 different modalities of PEG hydrogel in hydrophobic polystyrene wells. A total of 7500 cells/well (10,000 cells/cm(2)) were dispersed over the PEG filled wells and incubated in triplicates for 24 h, 7 and 13 days. Cell numbers were calculated by means of a NucleoCounter. Cell viability was determined by measuring lactate dehydrogenase (LDH). For statistical analysis, nonparametric Kruska-Wallis test followed by Dunetts T3 test were used. RESULTS:All PEG modifications showed good biocompatibility, as demonstrated by low LDH values per cell at the earlier two time points. After 13 days, all PEG modifications showed significantly lower number of cells compared with the controls, and the MX60 configurations demonstrated significantly higher LDH/cell values compared with the other hydrogels. CONCLUSIONS:Modifications of the physio-chemical properties of PEG hydrogels and the addition of RGD and spacers influenced the initial cellular response of cultured HGF-1 cells. With the exception of MX60 after 13 days, all PEG formulations performed similarly well. Early cellular response should be considered when developing PEG-based material for clinical purposes.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Dahlin C,Johansson A,Hoffman M,Molenberg Adoi
10.1111/clr.12076subject
Has Abstractpub_date
2014-01-01 00:00:00pages
16-20issue
1eissn
0905-7161issn
1600-0501journal_volume
25pub_type
杂志文章abstract:AIM:To review the literature on the prevalence and incidence of peri-implantitis. METHODS:Out of 322 potentially relevant publications we identified 29 articles concerning 23 studies, with information on the presence of signs of peri-implantitis in populations of at least 20 cases. RESULTS AND CONCLUSIONS:All studies...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2012.02541.x
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:The important item of aesthetics is rarely included in evaluation studies. The aim of this study was to develop and validate an index for rating aesthetics of implant-supported single crowns and adjacent soft tissues. MATERIAL AND METHODS:Nine items were selected, which have an influence on the aesthetic re...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01128.x
更新日期:2005-12-01 00:00:00
abstract:AIM:This study sought to investigate dimensional changes to the alveolar bone following extraction and application of novel devices used for obturation of socket orifice (socket cap) and space maintenance in sockets with facial dehiscence (socket cage). MATERIAL AND METHODS:Six Macaca fascicularis had six teeth each r...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12521
更新日期:2016-01-01 00:00:00
abstract:AIMS/BACKGROUND:Empirically, for implant placement associated with sinus floor augmentation, a minimum of five mm of residual crestal bone height has been recommended in order to achieve sufficient initial implant stability. It has been the aim of the study to test this assumption in an experimental animal trial. MATE...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01570.x
更新日期:2009-08-01 00:00:00
abstract::The aim of this study was to evaluate the soft tissue conditions at osseo-integrated oral implants in relation to the width of masticatory mucosa. Thirty-nine patients who had received a full-arch fixed bridge reconstruction > or = 10 years ago or a partial reconstruction > or = 5 years ago on a total of 171 implants ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1994.050101.x
更新日期:1994-03-01 00:00:00
abstract:OBJECTIVES:Diabetes mellitus is currently classified as a relative contraindication for implant treatment because of microangiopathies with the consequence of impaired bone regeneration and higher rates of implant failure. The study aim was to investigate peri-implant bone formation in a diabetic animal model in compar...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02380.x
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of immortalized hypertrophic chondrocytes extracellular matrix (HCM) with or without the use of guided bone regeneration (GBR) on the healing of critical-size calvarial defects. MATERIAL AND METHODS:In 42 rats, 5 mm critical-size calvarial defects were surgically created. The animals ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02120.x
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:Recent studies have suggested that magnesium (Mg) ions exert a beneficial effect on implant osseointegration. This study assessed the osseointegration of nanoporous titanium (Ti) surface incorporating the Mg produced by hydrothermal treatment in rabbit cancellous bone to determine whether this surface would f...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02144.x
更新日期:2012-03-01 00:00:00
abstract:AIM:The aim of this biomechanical study was to assess the influence of self-tapping blades in terms of primary implant stability between implants with self-tapping blades and implants without self-tapping blades using five different analytic methods, especially in medium-density bone. MATERIALS AND METHODS:Two differe...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02089.x
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to investigate the relationships among reported methodological, statistical, clinical and paratextual variables of randomized clinical trials (RCTs) in implant therapy, and their influence on subsequent research. MATERIALS AND METHODS:The material consisted of the RCTs in im...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01350.x
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:In the replacement of missing teeth, a paradigm shift is currently observed with immediate implant placement and/or restoration, particularly in the aesthetic zone. In molar sites, however, anatomical, occlusal and biomechanical considerations remain deterrent factors influencing the outcome of this treatmen...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02415.x
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to assess the influence of either recombinant human growth and differentiation factor 5 (rhGDF-5)- or recombinant human bone morphogenetic protein 2 (rhBMP-2)-coated natural bone mineral (NBM) on guided bone regeneration in a rat calvarial defect model. MATERIAL AND METHODS:...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2009.01796.x
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the success rate of chemically modified and conventional sandblasted acid-etched surface (SLA) titanium implants in irradiated oral squamous cell carcinoma patients. MATERIAL AND METHODS:Twenty patients with a mean age of 61.1 years were treated with dental implants after ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0501.2010.02050.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To assess the influence of a collagen membrane placed subjacent to a pristine sinus mucosa on the healing outcome of a sinus floor elevation procedure. MATERIALS AND METHODS:Eight Pelibuey sheep (Cubano rojo) underwent sinus floor elevation on both sides of the maxilla. At a randomly selected side (test), a ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12762
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:Collagen membranes are not limited to be occlusive barriers as they actively support bone regeneration. However, the impact of bone-derived growth factors on their osteoconductive competence has not been examined. METHODS:Twenty adult Sprague Dawley rats were included in the study. Calvaria defects with a d...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13133
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVES:To evaluate the reliability and failure modes of regular and horizontal mismatched platforms for implant-abutment connection varying the implant diameter. MATERIAL AND METHODS:Regular (REG, n = 21, 4.0-mm-diameter implant) and horizontal mismatched (HM, n = 21, 4.6-mm-diameter implant) platform Ti-6Al-4V im...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02257.x
更新日期:2012-09-01 00:00:00
abstract::In the present study, the influence of initial instability on the healing of titanium implants was studied in 9 lop-eared rabbits. Titanium implants (Brånemark System) were inserted in the tibiae, a location with cortical bone only, in such a way that they were either stable (control), rotation-mobile, or totally mobi...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the influence of the crown-to-implant ratio (C/I) ratio and different implant prosthetic treatment modalities on crestal bone loss around dental implants placed in the posterior region. MATERIAL AND METHODS:A total of 192 ITI dental implants were consecutively placed in premolars and molars of 83...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0501.2006.01307.x
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the synergistic effect of bone morphogenetic protein 2 (BMP-2) and vascular endothelial growth factor (VEGF) on the repair of bone defects around dental implants. MATERIAL AND METHODS:Five groups of scaffold were fabricated by a freeze-drying method, including pure chitosan/collagen scaffold; sca...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02164.x
更新日期:2012-04-01 00:00:00
abstract::The present study was designed to test perforated and non-perforated barriers for their ability to promote augmentation of bone tissue. More specifically, 1 totally occlusive barrier and 6 barriers with perforation sizes of about 10, 25, 50, 75, 100, and 300 microns and 1 group with no barriers placed (open test chamb...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1998.090406.x
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVES:Retrospectively, we assessed the likelihood that peri-implantitis was associated with a history of systemic disease, periodontitis, and smoking habits. METHODS:Data on probing pocket depth (PPD), bleeding on probing (BOP), and radiographic bone levels were obtained from individuals with dental implants. Per...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12208
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:This study aimed to determine bone level changes after 5-6 years of follow-up for a large group of one-stage dental implants consecutively placed in private practice. Potential confounding factors influencing crestal bone loss (CBL) were also assessed. MATERIALS AND METHODS:A total of 378 transmucosal Strau...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12083
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:Compare clinical outcomes of two types of dental implants with non-matching implant-abutment junctions loaded with fixed implant-borne reconstructions at 5 years of loading. MATERIALS AND METHODS:In 64 patients, one of two implant systems (S1, S2) was randomly used to support fixed dental prostheses (FDP). ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13526
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to determine the relationship between patients with a history of periodontitis and development of cement-related peri-implant disease. MATERIALS AND METHODS:Seventy-seven patients with 129 implants for this retrospective analysis were selected from completed implant cases that ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02570.x
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:To determine attitudes of general dental practitioners in a community where provision dental implants is a well-known treatment modality; and to identify variations in the attitudes with respect to dentists' factors, training factors and implant provision factors. METHODS:A questionnaire survey to a random ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02537.x
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To compare: (i) the incidence of soft tissue dehiscences; (ii) bone resorption before and after implant placement; and (iii) the survival and success rates of implants placed in two groups of patients with severe bone defects of the jaws reconstructed with autogenous onlay bone grafts alone (control group) or i...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02485.x
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVES:To study the peri-implant bone organization pattern of immediately loaded (IL) zirconia implants with microgrooved surfaces. MATERIALS AND METHODS:Forty-eight dental implants of 4 mm diameter and 10 mm length were inserted after two months postextraction healing in the edentulous mandible of six dogs. Three...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12461
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the reproducibility and the accuracy of volumetric measurements of specimens imitating localized alveolar ridge defects using an optical three-dimensional (3D) system. MATERIAL AND METHODS:Eight pairs of specimens (five with a cuboid and three with a geometrically compl...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01382.x
更新日期:2007-10-01 00:00:00
abstract::In a prospective study, 20 patients who underwent harvesting of chin grafts as outpatients, were followed up for 12 months (3 further patients with incomplete follow-up data were excluded from the study). Preoperatively and 7 days, 1, 3, 6 and 12 months postoperatively, follow-up data were assessed. Evaluation of the ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2001.120510.x
更新日期:2001-10-01 00:00:00
abstract:OBJECTIVE:Graft consolidation follows a gradient that reflects the properties of bone substitutes at sites of sinus augmentation. Here we present an analytical method to investigate the process of graft consolidation taking the distance from the maxillary host bone into account. MATERIAL AND METHODS:We therefore evalu...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2009.01733.x
更新日期:2009-10-01 00:00:00