Distributions of Magnetic Resonance Diffusion and Spectroscopy Measures with Traumatic Brain Injury.

abstract：:Controlled cortical impact (CCI) is a contemporary model of experimental cerebral contusion. We examined the cerebrovascular and neuropathologic effects of a severe CCI in rats. The utility of magnetic resonance imaging (MRI) for the assessment of contusion volume after severe CCI was also established. Severe CCI (3.0...

journal_title：Journal of neurotrauma

authors： Kochanek PM,Marion DW,Zhang W,Schiding JK,White M,Palmer AM,Clark RS,O'Malley ME,Styren SD,Ho C

更新日期：1995-12-01 00:00:00

abstract：:This study evaluated the utility of the Balance Error Scoring System (BESS) and the Sensory Organization Test (SOT) as tools for the screening and monitoring of Service members (SMs) with mild traumatic brain injury (mTBI) in a deployed setting during the acute and subacute phases of recovery. Patient records (N = 699...

journal_title：Journal of neurotrauma

authors： Haran FJ,Slaboda JC,King LA,Wright WG,Houlihan D,Norris JN

更新日期：2016-04-01 00:00:00

abstract：:Previous studies from our laboratory have shown the neuroprotective potential of ketones after TBI in the juvenile brain. It is our premise that acutely after TBI, glucose may not be the optimum fuel and decreasing metabolism of glucose in the presence of an alternative substrate will improve cellular metabolism and r...

journal_title：Journal of neurotrauma

authors： Prins ML,Hovda DA

更新日期：2009-07-01 00:00:00

abstract：:Traumatic Brain Injury (TBI) can be associated with partial or total smell loss. Recent studies have suggested that olfactory outcome can be positively modulated after olfactory training (OT). This study's aim was to investigate OT's potential role in smell recovery after TBI-induced olfactory loss. A prospective, ran...

journal_title：Journal of neurotrauma

authors： Langdon C,Lehrer E,Berenguer J,Laxe S,Alobid I,Quintó L,Mariño-Sánchez F,Bernabeu M,Marin C,Mullol J

更新日期：2018-11-15 00:00:00

abstract：:The generation of oxygen radicals and the process of lipid peroxidation have become a focus of attention for investigators in the fields of central nervous system (CNS) injury and stroke (e.g., ischemia). While absolute proof for their involvement in the pathophysiology of traumatic and ischemic damage to the CNS rema...

journal_title：Journal of neurotrauma

authors： Braughler JM,Hall ED

更新日期：1992-03-01 00:00:00

abstract：:Pairing vagus nerve stimulation (VNS) with rehabilitation has emerged as a potential strategy to enhance plasticity and improve recovery in a range of neurological disorders. A recent study highlights the therapeutic promise of VNS in promoting motor recovery after spinal cord injury (SCI). We investigated the safety ...

journal_title：Journal of neurotrauma

authors： Sachdeva R,Krassioukov AV,Bucksot JE,Hays SA

更新日期：2020-05-01 00:00:00

abstract：:Traumatic brain injuries (TBI) sustained in combat frequently co-occur with significant bodily injuries. Intuitively, more extensive bodily injuries might be associated with increased symptom reporting. In 2012, however, French et al. demonstrated an inverse relation between bodily injury severity and symptom reportin...

journal_title：Journal of neurotrauma

authors： French LM,Lange RT,Marshall K,Prokhorenko O,Brickell TA,Bailie JM,Asmussen SB,Ivins B,Cooper DB,Kennedy JE

更新日期：2014-10-01 00:00:00

abstract：:Risk factors for head injury are also risk factors for becoming homeless but there is little research on this vulnerable group, who can be neglected by health services that specialize in acquired brain injury. This study investigates the prevalence of admissions to hospital with a head injury in the homeless and assoc...

journal_title：Journal of neurotrauma

authors： McMillan TM,Laurie M,Oddy M,Menzies M,Stewart E,Wainman-Lefley J

更新日期：2015-01-15 00:00:00

abstract：:Many patients with mild traumatic brain injury (MTBI) concurrently sustain extracranial injuries; however, little is known about the impact of these additional injuries on outcome. We assessed the impact of additional injuries on the severity of postconcussional symptoms (PCS) and functional outcome 6 months post-inju...

journal_title：Journal of neurotrauma

authors： Stulemeijer M,van der Werf SP,Jacobs B,Biert J,van Vugt AB,Brauer JM,Vos PE

更新日期：2006-10-01 00:00:00

abstract：:Acute pain is a common symptom experienced after spinal cord injury (SCI). The presence of this pain calls for treatment with analgesics, such as buprenorphine. However, there are concerns that the drug may exert other effects besides alleviation of pain. Among those reported are in vitro changes in gene expression, a...

journal_title：Journal of neurotrauma

authors： Santiago JM,Rosas O,Torrado AI,González MM,Kalyan-Masih PO,Miranda JD

更新日期：2009-10-01 00:00:00

abstract：:This study characterized the Infinite Horizon (IH) Impactor for use in mouse models of contusion spinal cord injury (SCI), and investigated the feasibility and reliability of using magnetic resonance imaging (MRI) as a method to accurately measure lesion volume after mouse contusion SCI. Eight-week-old female C57Bl/6 ...

journal_title：Journal of neurotrauma

authors： Nishi RA,Liu H,Chu Y,Hamamura M,Su MY,Nalcioglu O,Anderson AJ

更新日期：2007-04-01 00:00:00

abstract：:Poor response inhibition is a hallmark of pediatric traumatic brain injury (TBI). We assessed motor response inhibition by measuring commission error rates on Simple (minimized cognitive demands) and Motivation (monetary reward) Go/No-Go tasks, comparing 17 children with chronic TBI (>1 year post-injury) and 14 matche...

journal_title：Journal of neurotrauma

authors： Stephens JA,Salorio CF,Gomes JP,Nebel MB,Mostofsky SH,Suskauer SJ

更新日期：2017-11-15 00:00:00

abstract：:Whiplash injury, commonly encountered in road traffic accidents, is a major cause of morbidity. Its pathophysiology is not well understood, and diagnosis remains clinical. Imaging and electrophysiological methods have not provided objective diagnostic evidence. Availability of a sensitive and specific diagnostic metho...

journal_title：Journal of neurotrauma

authors： Lo YL,Tan YE,Fook-Chong S,Boolsambatra P,Yue WM,Chan LL,Tan SB

更新日期：2007-06-01 00:00:00

abstract：:Despite the shift in demographics of spinal cord injury (SCI) due to an aging population, relatively little has been reported regarding the effect of age on outcomes after SCI. This study examines the potential confounding effect of co-morbidities on the age-related differences in the hospital mortality following acut...

journal_title：Journal of neurotrauma

authors： Furlan JC,Kattail D,Fehlings MG

更新日期：2009-08-01 00:00:00

abstract：:Penetrating traumatic brain injury (PTBI) is one of the major cause of death and disability worldwide. Previous studies with penetrating ballistic-like brain injury (PBBI), a PTBI rat model revealed widespread perilesional neurodegeneration, similar to that seen in humans following gunshot wound to the head, which is ...

journal_title：Journal of neurotrauma

authors： Spurlock MS,Ahmed AI,Rivera KN,Yokobori S,Lee SW,Sam PN,Shear DA,Hefferan MP,Hazel TG,Johe KK,Gajavelli S,Tortella FC,Bullock RM

更新日期：2017-06-01 00:00:00

abstract：:Using diffusion tensor imaging (DTI), we assessed the relationship of white matter integrity and performance on the Boston Naming Test (BNT) in a group of retired professional football players and a control group. We examined correlations between fractional anisotropy (FA) and mean diffusivity (MD) with BNT T-scores i...

journal_title：Journal of neurotrauma

authors： Strain JF,Didehbani N,Spence J,Conover H,Bartz EK,Mansinghani S,Jeroudi MK,Rao NK,Fields LM,Kraut MA,Cullum CM,Hart J Jr,Womack KB

更新日期：2017-01-15 00:00:00

abstract：:Neuroendocrine disturbances are common after traumatic brain injury (TBI) and aneurysmal subarachnoid hemorrhage (SAH), but only a few data exist on long-term anterior pituitary deficiencies after brain injury. We present data from the Structured Data Assessment of Hypopituitarism after TBI and SAH, a multi-center stu...

journal_title：Journal of neurotrauma

authors： Krewer C,Schneider M,Schneider HJ,Kreitschmann-Andermahr I,Buchfelder M,Faust M,Berg C,Wallaschofski H,Renner C,Uhl E,Koenig E,Jordan M,Stalla GK,Kopczak A

更新日期：2016-08-15 00:00:00

abstract：:Neuropathic pain develops in 40-70% of spinal cord injury (SCI) patients and markedly compromises quality of life. We examined plasma from SCI patients for autoantibodies to glial fibrillary acidic protein (GFAP) and collapsin response mediator protein-2 (CRMP2) and evaluated their relationship to the development of n...

journal_title：Journal of neurotrauma

authors： Hergenroeder GW,Redell JB,Choi HA,Schmitt L,Donovan W,Francisco GE,Schmitt K,Moore AN,Dash PK

更新日期：2018-11-01 00:00:00

abstract：:This study created a framework incorporating provider perspectives of best practices for early psychosocial intervention to improve caregiver experiences and outcomes after severe pediatric traumatic brain injury (TBI). A purposive sample of 23 healthcare providers from the emergency, intensive care, and acute care de...

journal_title：Journal of neurotrauma

authors： Erlick MR,Vavilala MS,Jaffe KM,Blayney CB,Moore M

更新日期：2020-11-09 00:00:00

abstract：:Traumatic brain injury (TBI) in humans and in animals leads to an acute and sustained increase in tissue glutamate concentrations within the brain, triggering glutamate-mediated excitotoxicity. Excitatory amino acid transporters (EAATs) are responsible for maintaining extracellular central nervous system glutamate con...

journal_title：Journal of neurotrauma

authors： Fontana AC,Fox DP,Zoubroulis A,Mortensen OV,Raghupathi R

更新日期：2016-06-01 00:00:00

abstract：:Pediatric traumatic brain injury (TBI) research depends on comparisons of profiles and outcomes between brain-injured individuals and groups consisting either of injured controls (e.g., orthopedic injuries, OI) or uninjured, typically developing children recruited from the community (community controls, CC). Children ...

journal_title：Journal of neurotrauma

authors： Beauchamp MH,Landry-Roy C,Gravel J,Beaudoin C,Bernier A

更新日期：2017-09-01 00:00:00

abstract：:The aim of this study was to evaluate the neuroprotective efficacy of the inert gas xenon as a treatment for patients with blast-induced traumatic brain injury in an in vitro laboratory model. We developed a novel blast traumatic brain injury model using C57BL/6N mouse organotypic hippocampal brain-slice cultures expo...

journal_title：Journal of neurotrauma

authors： Campos-Pires R,Koziakova M,Yonis A,Pau A,Macdonald W,Harris K,Edge CJ,Franks NP,Mahoney PF,Dickinson R

更新日期：2018-04-15 00:00:00

abstract：:Glycosylation is a fundamental cellular process that has a dramatic impact on the functionality of glycoconjugates such as proteins or lipids and mediates many different biological interactions including cell migration, cellular signaling, and synaptic interactions in the nervous system. In spinal cord injury (SCI), a...

journal_title：Journal of neurotrauma

authors： Osimanjiang W,Roballo KCS,Houck BD,Ito M,Antonopoulos A,Dell A,Haslam SM,Bushman JS

更新日期：2020-09-15 00:00:00

abstract：:Chronic pain and dysesthesias are debilitating conditions that can arise following spinal cord injury (SCI). Research studies frequently employ rodent models of SCI to better understand the underlying mechanisms and develop better treatments for these phenomena. While evoked withdrawal tests can assess hypersensitivit...

journal_title：Journal of neurotrauma

authors： Hoschouer EL,Finseth T,Flinn S,Basso DM,Jakeman LB

更新日期：2010-05-01 00:00:00

abstract：:The endoplasmic reticulum stress response (ERSR) is activated in a variety of neurodegenerative diseases and/or traumatic injuries. Subsequent restoration of ER homeostasis may contribute to improvement in the functional outcome of these diseases. We recently demonstrated improvements in hindlimb locomotion after thor...

journal_title：Journal of neurotrauma

authors： Saraswat Ohri S,Mullins A,Hetman M,Whittemore SR

更新日期：2018-02-01 00:00:00

abstract：:Death of Central Nervous System (CNS) neurons following traumatic brain injury (TBI) is a complex process arising from a combination of factors, many of which are still unknown. It has been found that inhibition of transient receptor potential (TRP) channels constitutes an effective strategy for preventing death of CN...

journal_title：Journal of neurotrauma

authors： Peters M,Trembovler V,Alexandrovich A,Parnas M,Birnbaumer L,Minke B,Shohami E

更新日期：2012-12-10 00:00:00

abstract：:Brain injury after high-level blast has been established both clinically and experimentally. Less is known about the effects on the brain of exposure to low to moderate blast levels, such as those encountered by military personnel during the firing of weapons. This study investigates if exposure to occupational levels...

journal_title：Journal of neurotrauma

authors： Säljö A,Svensson B,Mayorga M,Hamberger A,Bolouri H

更新日期：2009-08-01 00:00:00

abstract：:The role of Ca2+ in cellular injury has received particular attention in studies of acute spinal cord trauma. In this context, the spatial and temporal distribution of extracellular Ca2+ ([Ca2+]e) may have an important bearing on the development of secondary tissue injury. We therefore studied the spatial-temporal dis...

journal_title：Journal of neurotrauma

authors： Moriya T,Hassan AZ,Young W,Chesler M

更新日期：1994-06-01 00:00:00

abstract：:Mild traumatic brain injury (mTBI) accounts for the majority of head trauma cases. Despite some lasting cognitive, emotional, and behavioral deficits, there are frequently no overt morphological defects, suggesting that changes may result from alterations in the physiology of individual neurons. We investigated hippoc...

journal_title：Journal of neurotrauma

authors： Eakin K,Miller JP

更新日期：2012-04-10 00:00:00

abstract：:Traumatic brain injury (TBI) is known to be accompanied by an increase in intracranial pressure (ICP) and in some cases, by spontaneous generation of cortical spreading depression (CSD) cycles. However, the role of CSD in the pathophysiology of cerebral contusion is still unknown. A multiparametric monitoring assembly...

journal_title：Journal of neurotrauma

authors： Rogatsky GG,Sonn J,Kamenir Y,Zarchin N,Mayevsky A

更新日期：2003-12-01 00:00:00